Cited by 157Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPsychotherapy Techniques and ApplicationsPsychological Treatments and Assessments

Efficacy of Cognitive Behavioral Therapy for Generalized Anxiety Disorder in Older Adults: Systematic Review, Meta-Analysis, and Meta-Regression

Hall, Jo, Kellett, Stephen, Berrios, Raul, Bains, Manreesh Kaur, Scott, Shonagh·2016·The American Journal of Geriatric Psychiatry

Abstract

Objective Generalized anxiety disorder (GAD) is a common disorder in older adults producing functional impairment, and psychotherapy is the preferred treatment option. Meta-analytic methods sought to determine the efficacy of outpatient cognitive behavioral therapy (CBT) with respect to the hallmark feature of GAD-uncontrolled and excessive worry. In order to optimize clinical applicability, variables associated with GAD treatment outcomes were also examined.Methods Systematic search of relevant databases and iterative searches of references from articles retrieved. All studies were required to have been a randomized control trial (RCT), to have used the Penn State Worry Questionnaire (PSWQ) or its abbreviated version (PSWQ-A) as an outcome measure, and to have conducted CBT with outpatient older adults. Fourteen RCTs (N = 985) were suitable and random-effects meta-analyses and univariate meta-regressions were conducted.Results At the end of treatment, and at 6-month follow-up, significant treatment effects favoring CBT were found in comparison to a waitlist or treatment-as-usual. When CBT was compared with active controls, a small nonsignificant treatment advantage was found for CBT at the end of treatment, with equivalence of outcomes at follow-up. Treatment effect size of CBT for GAD was significantly associated with attrition rates and depression outcomes.Conclusions CBT is more helpful than having no treatment for GAD in later life. Nevertheless, whether CBT shows long-term durability, or is superior to other commonly available treatments (such as supportive psychotherapy), remains to be tested. The relationship between treatment effects for GAD and depression following CBT warrants further research.

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  1. [37]37. Stanley MA, Wilson NL, Amspoker AB: Lay providers can deliver effective cognitive behavior therapy for older adults with generalized anxiety disorder: A randomized trial. Depress Anxiety 2014; 31:391-401

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Authors
Hall, J., Kellett, S., Berrios, R., Bains, M. K., & Scott, S.
Affiliations
  • University of Sheffield (GB)
  • Sheffield Health and Social Care NHS Foundation Trust (GB)
Corresponding author
Hall, Jo
Venue
The American Journal of Geriatric Psychiatry
Publisher
Elsevier BV
Published
2016-11
Volume
24
Issue
11
Pages
1063-1073
ISSN
1064-7481 (ISSN-L)
OpenAlex
W2429546986
Cited by
157
References
74
Citations by year
2026: 8 · 2025: 19 · 2024: 17 · 2023: 23 · 2022: 17 · 2021: 22 · 2020: 21 · 2019: 11 · 2018: 9 · 2017: 9 · 2016: 1
FWCI
1.31
Type
journal article
Language
en
Open access
closed
Locations
  • American Journal of Geriatric Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
  • White Rose Research Online (University of Leeds, The University of Sheffield, University of York) (acceptedVersion)
Topics
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
  • Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Assessments
Keywords
generalized anxiety disorder, cognitive behavioral therapy, older adults, outpatient psychotherapy, Penn State Worry Questionnaire, worry, treatment discontinuation, depression, treatment durability, psychotherapy efficacy
MeSH terms
Aged, Anxiety Disorders, Humans, Regression Analysis, Cognitive Behavioral Therapy, Treatment Outcome

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