Cognitive-behavioral therapy for late-life anxiety: Similarities and differences between Veteran and community participants
Open accessAbstract
Cognitive-behavioral therapy (CBT) is an evidence-based treatment for anxiety; however, a growing body of research suggests that CBT effect sizes are smaller in Veteran samples. The aim of this study was to perform secondary data analyses of a randomized controlled trial of CBT for late-life generalized anxiety disorder compared with treatment as usual (TAU) in a Veteran (n = 101) and community-based (n= 122) sample. Veterans had lower income and less education than community participants, greater severity on baseline measures of anxiety and depression, poorer physical health, and higher rates of psychiatric comorbidity. Treatment effects were statistically significant in the community sample (all ps< 0.01), but not in Veterans (all ps> 0.05). Further analyses in Veterans revealed that poorer perceived social support significantly predicted poorer outcomes (all ps< 0.05). Our results underscore the complexity of treating Veterans with anxiety, and suggest that additional work is needed to improve the efficacy of CBT for Veterans, with particular attention to social support. © 2015.
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Claims the paper makes
13 of 47 cited sources checked · 9 supported · 0 flagged · accuracy not yet measured
- Premisecitation
Among VA primary care patients, GAD is highly prevalent.
“GAD is highly prevalent among VA primary care patients”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites Milanak, Gros, Magruder, Brawman-Mintzer & Frueh, 2013 source
- Premisecitation
GAD is associated with substantial impairment in functioning among VA primary care patients.
“is associated with substantial impairment in functioning (Milanak, Gros, Magruder, Brawman-Mintzer & Frueh, 2013)”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites Milanak, Gros, Magruder, Brawman-Mintzer & Frueh, 2013 source
- Premisecitation
This CBT protocol has shown efficacy in previous trials of CBT for late-life generalized anxiety disorder in primary care.
“This protocol has demonstrated efficacy in prior trials of CBT for late-life GAD in primary care (Calleo et al., 2013; Stanley et al., 2003, 2009).”
Quote in the paperSubstantial claim1 of 2 sources checked- cites Calleo et al., 2013 source
The Introduction says earlier trials found positive effects of CBT for late-life GAD in primary care. But it describes this paper’s protocol as an adaptation of earlier interventions, and the Discussion and Results report only preliminary improvements from an uncontrolled pilot. The paper therefore supports promising outcomes for the adapted protocol, not demonstrated efficacy for that same protocol in prior trials. (LLM, conf=0.84)
Experimental — accuracy not yet measured - cites Stanley et al., 2003, 2009
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Premisecitation
Telemedicine collaborative care for depression in Veterans produced smaller symptom-improvement effects than a comparable study in federally qualified health center patients.
“a study of telemedicine-based collaborative care for depression in Veterans (Fortney et al., 2007) found smaller effect sizes for symptom improvement than a similar study of telemedicine-based collaborative care in patients from federally qualified health centers (Fortney et al., 2013)”
Quote in the paperNot a substantial claim1 of 2 sources checked - Premisecitation
Previous studies examining treatment outcome for PTSD between Veteran cohorts suggest poorer treatment outcome in Vietnam-era Veterans than in returning Veterans from Iraq and Afghanistan.
“Previous studies examining treatment outcome for PTSD between Veteran cohorts suggest poorer treatment outcome in Vietnam-era Veterans than in returning Veterans from the wars in Iraq and Afghanistan (Chard, Schumm, Owens, & Cottingham, 2010; Eftekhari et al., 2013; but see Yoder et al., 2012).”
Quote in the paperNot a substantial claim1 of 3 sources checked
- Premisecitation
In an analysis restricted to the two CBT arms, subsample predicted response: community CBT recipients improved more in anxiety and worry than Veteran CBT recipients.
“A secondary examination of only data from the two CBT conditions found that subsample (community vs. Veteran participants) was a predictor of treatment response, such that community participants receiving CBT showed greater improvements in anxiety and worry symptoms than Veteran participants receiving CBT (Hundt et al., 2014)”
Quote in the paperSubstantial claim1 of 1 sources checked- cites Hundt et al., 2014 source
- Findingown data
Treatment effects were not statistically significant in the Veteran sample.
“but not in Veterans (all ps > .05)”
Quote in the paperSubstantial claim - Findingown data
In Veterans, poorer perceived social support significantly predicted poorer outcomes.
“poorer perceived social support significantly predicted poorer outcomes (all ps <.05)”
Quote in the paperSubstantial claim - Findingown data
In the community sample, treatment effects reached statistical significance.
“Treatment effects were statistically significant in the community sample (all ps < .01)”
Quote in the paperSubstantial claim - Findingown data
Veterans had lower income than community participants.
“Veterans had lower income and less education than community participants”
Quote in the paperNot a substantial claim - Findingown data
Veterans had greater baseline depression severity than community participants.
“greater severity on baseline measures of anxiety and depression”
Quote in the paperNot a substantial claim - Findingown data
Veterans had less education than community participants.
“Veterans had lower income and less education than community participants”
Quote in the paperNot a substantial claim - Findingown data
Veterans had greater baseline anxiety severity than community participants.
“greater severity on baseline measures of anxiety and depression”
Quote in the paperNot a substantial claim - Findingown data
Veterans had poorer physical health than community participants.
“poorer physical health”
Quote in the paperNot a substantial claim - Findingown data
Veterans had higher rates of psychiatric comorbidity than community participants.
“higher rates of psychiatric comorbidity”
Quote in the paperNot a substantial claim - Findingown data
The Veteran and community subsamples differed significantly on most demographic and clinical variables and on health service use.
“The Veteran and community subsamples significantly differed on the majority of demographic and clinical variables, as well as health service use.”
Quote in the paperNot a substantial claim - Findingown data
ITT analyses showed significant main effects of treatment for all four measures in the community sample.
“ITT analyses revealed significant main effects of treatment for all four measures in the community sample (all ps < .01), but not in the Veteran sample (all ps > .05; see Table 2).”
Quote in the paperSubstantial claim - Findingown data
Of 223 randomized participants, 21 Veterans (22%) and 14 community participants (17%) did not complete the six-month assessment and were considered dropouts.
“Of the 223 randomized participants, 21 Veterans (22%) and 14 community participants (17%) did not complete the 6 month assessment and were considered dropouts.”
Quote in the paperNot a substantial claim - Findingown data
The difference in dropout rates between Veteran and community participants was not statistically significant.
“This difference was not statistically significant (χ2(1) = 0.74, p = 0.39).”
Quote in the paperNot a substantial claim - Findingown data
There were no significant interactions between any individual predictor variable and treatment condition for the self-report outcomes (all ps > .07).
“There were no significant interactions between any individual predictor variable and treatment condition (all ps > .07, data not reported) for either analysis.”
Quote in the paperSubstantial claim - Findingown data
Veteran and community participants did not differ on perceived levels of social support at baseline.
“Interestingly, Veteran and community participants did not differ on perceived levels of social support at baseline; yet this finding that social support was the sole unique predictor for the Veteran sample suggests that perceived social support is an important factor in Veterans’ recovery, regardless of whether they received CBT or treatment as usual.”
Quote in the paperSubstantial claim - Findingown data
CBT pre-post effect sizes for the Veteran sample were small to moderate (d range = 0.29 - 0.55).
“These analyses revealed small to moderate CBT pre-post effect sizes for the Veteran sample (d range = 0.29 – 0.55), and moderate effect sizes for the civilian sample (d range = 0.63 – 0.73).”
Quote in the paperNot a substantial claim - Findingown data
Completer analyses revealed results similar to the ITT analyses.
“Completer analyses revealed similar results.”
Quote in the paperNot a substantial claim - Findingnone given
Imputed means were not statistically or substantially different from observed values.
“Imputed means were not statistically or substantially different from observed values.”
Quote in the paperNot a substantial claim - Findingown data
In the community sample, social support was not a significant predictor of either self-report or clinician-rated outcomes.
“Both ITT and completer multiple-regression analyses revealed that increased mental health service predicted worse 6-month STAI, GADSS, and SIGH-A scores, but that social support was not a significant predictor of either self-report or clinician-rated outcomes in the community sample.”
Quote in the paperSubstantial claim - Findingown data
In the community sample, increased mental health service use predicted worse 6-month STAI, GADSS, and SIGH-A scores.
“Both ITT and completer multiple-regression analyses revealed that increased mental health service predicted worse 6-month STAI, GADSS, and SIGH-A scores, but that social support was not a significant predictor of either self-report or clinician-rated outcomes in the community sample.”
Quote in the paperNot a substantial claim - Findingown data
UC effects were very small to small in both Veterans (d range = 0.17 - 0.34) and civilians (d range = −0.04 - 0.43).
“Conversely, UC effects were very small to small in both Veterans (d range = 0.17 – 0.34) and civilians (d range = −0.04 – 0.43), suggesting only minimal improvement in worry and anxiety symptoms for participants in usual care.”
Quote in the paperSubstantial claim - Findingown data
Multiple-regression results using ITT methods with GADSS as the dependent variable revealed no significant predictors of clinician-rated GAD severity at 6 months.
“Multiple-regression results using ITT methods with GADSS as the dependent variable revealed no significant predictors of clinician rated GAD severity at 6 months (see Table 4).”
Quote in the paperNot a substantial claim - Findingown data
Effect-size estimates in the Veteran sample suggested small improvements in all outcome measures for CBT relative to UC.
“Effect-size estimates in the Veteran sample suggested small improvements in all outcome measures for CBT relative to UC.”
Quote in the paperSubstantial claim - Findingown data
ITT analyses showed no significant main effects of treatment for any of the four measures in the Veteran sample.
“ITT analyses revealed significant main effects of treatment for all four measures in the community sample (all ps < .01), but not in the Veteran sample (all ps > .05; see Table 2).”
Quote in the paperSubstantial claim - Findingown data
There were no significant interactions between any individual predictor variable and treatment condition for the clinician-rated outcomes (all ps > .32).
“There were no significant interactions between any individual predictor variable and treatment condition (all ps > .32, data not reported) for either analysis.”
Quote in the paperSubstantial claim - Findingown data
Social support was the sole unique predictor for the Veteran sample.
“Interestingly, Veteran and community participants did not differ on perceived levels of social support at baseline; yet this finding that social support was the sole unique predictor for the Veteran sample suggests that perceived social support is an important factor in Veterans’ recovery, regardless of whether they received CBT or treatment as usual.”
Quote in the paperNot a substantial claim - Findingown data
CBT pre-post effect sizes for the civilian sample were moderate (d range = 0.63 - 0.73).
“These analyses revealed small to moderate CBT pre-post effect sizes for the Veteran sample (d range = 0.29 – 0.55), and moderate effect sizes for the civilian sample (d range = 0.63 – 0.73).”
Quote in the paperNot a substantial claim - Findingown data
In the Veteran sample, baseline social support and mental health service use were the only significant and unique predictors of self-report worry and anxiety severity.
“Multiple-regression results using ITT methods suggest that baseline social support and mental health service use were the only significant and unique predictors of self-report worry and anxiety severity (see Table 3).”
Quote in the paperNot a substantial claim - Findingown data
No significant differences in dropout rates between Veteran and community samples were found for either the CBT or UC conditions.
“Similarly, no significant differences in dropout rates between the Veteran and community samples were found for the CBT (χ2(1) = 1.31, p = 0.25) or UC conditions (χ2(1) = 0.09, p = 0.76).”
Quote in the paperNot a substantial claim - Premisecitation
Research suggests that CBT produces smaller effect sizes in Veteran samples than in community samples.
“a growing body of research suggests that CBT effect sizes are smaller in Veteran samples”
- Also stated in: § 1. Introduction · hedged
“growing body of research suggesting that CBT effect sizes for anxiety and depression are smaller for Veteran seeking care in the Veterans Health Administration (VHA) than for community samples (e.g., Bisson et al., 2007).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Bisson et al., 2007 source
- Also stated in: § 1. Introduction · hedged
- Premisecitation
CBT is an evidence-based treatment for anxiety.
“Cognitive-behavioral therapy (CBT) is an evidence-based treatment for anxiety”
- Also stated in: § 1. Introduction · boosted
“Cognitive-behavioral therapy (CBT) is an evidence-based treatment for GAD and has demonstrated efficacy in both younger and older adult civilian populations (Cuijpers et al., 2014).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Cuijpers et al., 2014 source
- Also stated in: § 1. Introduction · boosted
- Interpretationown data
These differences support previous assertions that Veterans tend to have more chronic and severe presentations than non-Veterans.
“the greater psychiatric symptom severity, poorer physical health status, and higher rates of psychiatric comorbidity among the Veteran sample support previous assertions that Veterans tend to have more chronic and severe presentations than non-Veterans (Goodson et al., 2011; Selim et al., 2004).”
Quote in the paperSubstantial claim0 of 2 sources checked - Premisecitation
The original three-arm RCT by our group found that both CBT conditions improved more than usual care at posttreatment across measures of worry, anxiety, depression, sleep, and mental health quality of life.
“Results demonstrated significant improvements in GAD severity, anxiety, depression, insomnia, and mental health quality of life at posttreatment in both CBT conditions relative to UC”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Stanley et al., 2014 source
- Interpretationown data
Participants in usual care showed only minimal improvement in worry and anxiety symptoms.
“Conversely, UC effects were very small to small in both Veterans (d range = 0.17 – 0.34) and civilians (d range = −0.04 – 0.43), suggesting only minimal improvement in worry and anxiety symptoms for participants in usual care.”
Quote in the paperSubstantial claim - Interpretationown data
These data add to growing evidence that standard CBT packages may produce smaller treatment effects for Veterans in the VA healthcare system than for civilians.
“These data add to the growing evidence that treatment effects for standard CBT packages may be smaller for Veterans in the VA healthcare system than for their civilian counterparts.”
Quote in the paperSubstantial claim - Premisecitation
In three meta-analyses of PTSD treatment, Veteran samples showed smaller effect sizes than non-Veteran samples.
“Three meta-analyses of CBT for PTSD found smaller treatment effect sizes for Veteran samples than for non-Veteran samples (Barrera, Mott, Hofstein, & Teng, 2013; Bisson et al., 2007; Bradley, Greene, Russ, Dutra, & Westen, 2005)”
Quote in the paperSubstantial claim0 of 3 sources checked - Premisecitation
When samples from those two studies were combined, Veteran status was a significant moderator of treatment outcome.
“When the samples from these two studies were combined to examine predictors of treatment outcome, Veteran status was a significant moderator (risk factor) for treatment outcome (Grubbs, Fortney, & Pyne, 2014)”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Grubbs, Fortney, & Pyne, 2014
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Interpretationreasoning
Participants from both subsamples with more complex and possibly treatment-refractory presentations were less likely to respond to the CBT intervention.
“Given that mental health service use also predicted treatment outcome in the community sample, this finding suggests that participants from both subsamples with more complex and possibly treatment-refractory presentations were less likely to respond to the CBT intervention.”
Quote in the paperSubstantial claim - Premisecitation
The original trial found no differences in outcomes between the expert-provider and bachelor-level-provider CBT conditions.
“with no differences in outcomes between the PLP and BLP conditions”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Stanley et al., 2014 source
- Premisecitation
CBT has demonstrated efficacy for GAD in younger and older adult civilian populations.
“has demonstrated efficacy in both younger and older adult civilian populations (Cuijpers et al., 2014)”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Cuijpers et al., 2014 source
- Interpretationown data
Complexities in psychiatric presentation and medical comorbidity likely influence Veteran treatment response.
“Complexities in psychiatric presentation and medical comorbidity likely influence Veteran treatment response.”
Quote in the paperSubstantial claim - Premisecitation
A trial of CBT for depression versus usual care in Veterans found no significant effect.
“a randomized controlled trial comparing CBT for depression to treatment as usual in Veterans yielded nonsignificant results (Mohr, Carmody, Erickson, Jin, & Leader, 2011)”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Mohr, Carmody, Erickson, Jin, & Leader, 2011 source
- Interpretationcitation
The unique experiences of the Vietnam Veteran cohort may negatively impact response to treatment.
“The unique experiences of the Vietnam Veteran cohort may negatively impact response to treatment.”
Quote in the paperNot a substantial claim- Rests on an assumption: The majority of CBT studies within Veteran samples have been conducted with Vietnam Veterans.
- Interpretationown data
Perceived social support is an important factor in Veterans' recovery, regardless of whether they received CBT or treatment as usual.
“Interestingly, Veteran and community participants did not differ on perceived levels of social support at baseline; yet this finding that social support was the sole unique predictor for the Veteran sample suggests that perceived social support is an important factor in Veterans’ recovery, regardless of whether they received CBT or treatment as usual.”
Quote in the paperSubstantial claim - Premisecitation
Social support has been identified as an important predictor in the onset and maintenance of anxiety and PTSD in Vietnam Veterans.
“Social support has been identified as an important predictor in the onset and maintenance of anxiety and PTSD in Vietnam Veterans (Boscarino, 1995; Schnurr, Lunney, & Sengupta, 2004) and may, therefore, be important to address directly in treatment.”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites Boscarino, 1995
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Schnurr, Lunney, & Sengupta, 2004 source
- Interpretationown data
The results highlight the challenges in successfully treating older Veterans within the VHA healthcare system.
“The results from this study highlight the challenges in successfully treating older Veterans within the VHA healthcare system.”
Quote in the paperSubstantial claim - Interpretationown data
The overlap in effect size confidence intervals raises the possibility that the differences between samples may not be clinically meaningful.
“While the findings from this study support previous research demonstrating smaller CBT treatment effects for Veterans compared to civilians, the overlap in effect size confidence intervals raises the possibility that these differences may not be clinically meaningful.”
Quote in the paperSubstantial claim - Interpretationnone given
The results from this study may not generalize to other populations, including Veterans of different eras, those seeking care outside the VHA system, and underserved, male, and/or minority individuals in the community.
“Finally, the results from this study may not generalize to other population including Veterans of different eras and those seeking care outside the VHA system, as well as underserved, male, and/or minority individuals in the community.”
Quote in the paperNot a substantial claim - Study design and conductreasoning
A lack of statistical power in detecting significant interactions between baseline sample characteristics and treatment allocation in the Veteran sample restricted the ability to determine whether CBT treatment response in Veterans can be predicted by factors such as demographics, symptom severity, psychiatric comorbidity, or physical health status.
“A lack of statistical power in detecting significant interactions between baseline sample characteristics and treatment allocation in the Veteran sample restricted our ability to determine whether CBT treatment response in Veterans can be predicted by factors such as demographics, symptom severity, psychiatric comorbidity, or physical health status.”
Quote in the paperNot a substantial claim - Study design and conductnone given
A limitation of this work is that it is a secondary data analysis of a study that was not originally powered to detect differences in subsamples.
“Limitations to this work include secondary data analysis of a study that was not originally powered to detect differences in subsamples.”
Quote in the paperSubstantial claim
- May combine two claims. 20
- Classified as probably not a substantial claim. 25
- The quote only partly states this claim. 2
May combine two claims.
Study design and conductcitationThe PSWQ-A can identify GAD in older primary care patients and can detect treatment-related change.
“The PSWQ-A is useful for identifying GAD in older primary care patients (Webb et al., 2008), is capable of demonstrating change following treatment (Stanley et al., 2009; Shrestha et al., 2012)”
Quote in the paperSubstantial claim2 of 3 sources checked- cites Webb et al., 2008 source
- cites Stanley et al., 2009 source
Stanley et al. support the treatment-change portion in part: the Results (Post-treatment Outcomes) report significantly greater improvement after CBT on a worry questionnaire. But the Methods (Measures and Data Collection) specify that this was the 16-item PSWQ, not the PSWQ-A, so the paper does not establish that the abbreviated version detects treatment-related change. The identification claim is attributed to Webb et al., not Stanley et al. (LLM, conf=0.88)
Experimental — accuracy not yet measured - cites Shrestha et al., 2012
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductcitationThe GADSS has adequate psychometric properties among older adults.
“has adequate psychometric properties among older adults (Andreescu et al., 2008; Weiss et al., 2009).”
Quote in the paperNot a substantial claim2 of 2 sources checked- cites Andreescu et al., 2008 source
- cites Weiss et al., 2009 source
The Discussion reports adequate internal consistency and convergent validity, strong inter-rater reliability, and a unidimensional factor structure. But it concludes that psychometric properties were mixed among older adults in primary care, citing poor diagnostic accuracy and weak divergent validity; the unqualified claim overstates the findings. (LLM, conf=0.88)
Experimental — accuracy not yet measured
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductcitationThe PHQ-9 has strong psychometric properties among older adults, and the PHQ-8 and PHQ-9 are highly correlated.
“Psychometric properties of the PHQ-9 are strong among older adults, and the two versions of the scale are highly correlated (Razykov, Ziegelstein, Whooley, & Thombs, 2012).”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites Razykov, Ziegelstein, Whooley, & Thombs, 2012 source
The PHQ-9 Versus the PHQ-8 results (page not provided) report a very high correlation between the scales (r = 0.997). The paper assesses outpatients with coronary artery disease, not older adults as a group, and does not establish that the PHQ-9 has strong psychometric properties among older adults. (LLM, conf=0.88)
Experimental — accuracy not yet measured
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductcitationThe SIGH-A has demonstrated sensitivity to change in clinical trials.
“The SIGH-A is a 14-item measure with demonstrated sensitivity to change in clinical trials (Brenes et al., 2012).”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites Brenes et al., 2012 source
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationRecent data suggest that peer support interventions are valued by Veterans and have the potential to reduce psychiatric symptoms.
“Recent data suggest that peer support interventions are valued by Veterans (Jain, McLean, & Rosen, 2012) and have the potential to reduce psychiatric symptoms (Barber, Rosenheck, Armstrong, & Resnick, 2008; Pfeiffer, Heisler, Piette, Rogers, & Valenstein, 2011).”
Quote in the paperNot a substantial claim1 of 3 sources checkedThe quote only partly states this claim.
Findingown dataCompleter analyses for the self-report predictors revealed similar results.
“Completer analyses revealed similar results.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataITT multiple regression results with SIGH-A as the dependent variable revealed mental health service use as the only significant predictor, with increased use predicting worse clinician-rated anxiety severity.
“ITT multiple regression results with SIGH-A as the dependent variable revealed mental health service use as the only significant predictor, such that increased mental health service use predicted worse clinician-rated anxiety severity.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingnone givenThe Veterans included in this study were primarily of the Vietnam era.
“The Veterans included in this study were primarily of the Vietnam era; and, in fact, the majority of CBT studies within Veteran samples have been conducted with Vietnam Veterans.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataAlthough effect-size estimates were numerically larger in the community sample, overlapping confidence intervals suggest the effects are not statistically different between community and Veteran samples.
“Although the effect-size estimates are numerically larger in the community sample than in the Veteran sample, the overlapping confidence intervals suggest that the effects are not statistically different between community and Veteran samples.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataPoorer perceived social support and increased mental health service use predicted poorer outcomes on self-report measures of worry and anxiety.
“The direction of these relationships indicate that poorer perceived social support and increased use of mental health services predict poorer outcomes on self-report measures of worry and anxiety.”
Quote in the paperNot a substantial claimThe quote only partly states this claim.
Findingown dataCompleter analyses for the clinician-rated predictors revealed similar results.
“Completer analyses revealed similar results.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataEffect-size estimates in the community sample suggested moderate improvements in worry and anxiety and large improvements in GAD symptom severity for CBT relative to UC.
“Effect-size estimates in the community sample suggested moderate improvements in worry and anxiety, and large improvements in GAD symptom severity for CBT relative to UC.”
Quote in the paperSubstantial claimMay combine two claims.
FindingcitationThe Veteran sample had greater psychiatric symptom severity, poorer physical health status, and higher rates of psychiatric comorbidity than the community sample.
“the greater psychiatric symptom severity, poorer physical health status, and higher rates of psychiatric comorbidity among the Veteran sample support previous assertions that Veterans tend to have more chronic and severe presentations than non-Veterans (Goodson et al., 2011; Selim et al., 2004).”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductnone givenAssessments were done by telephone; evaluators did not know treatment assignment and had no other project involvement.
“All assessments were administered via telephone, and IEs were unaware of treatment assignment and not involved in any other way with the project.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationThe CBT protocol used in this study was based on elements of earlier CBT protocols for generalized anxiety disorder in younger adults and was modified for flexible delivery to older adults in primary care.
“The CBT protocol utilized in this study is based on elements of prior CBT protocols for GAD in younger adults (Borkovec & Costello, 1993; Craske, Barlow, & O’Leary, 1992) and modified to include a flexible delivery format to meet the needs of older adults in primary care medical settings (Stanley, Diefenbach, & Hopko, 2004).”
Quote in the paperNot a substantial claim0 of 3 sources checkedProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductcitationThe MSPSS has good psychometric properties in older adults.
“with good psychometric properties in older adults (Stanley, Beck, & Zebb, 1998).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Stanley, Beck, & Zebb, 1998 source
Classified as probably not a substantial claim. May combine two claims.
Study design and conductown dataParticipants were randomly assigned to one of three treatment conditions (CBT by PLP, CBT by BLP, or UC) within each subsample, using a 1:1:1 ratio in blocks of nine.
“Patients were randomly assigned to treatment condition (CBT delivered by PLP, CBT delivered by BLP, or UC) within each subsample (Veteran vs. community) according to a 1:1:1: ratio within blocks of nine.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing), S4 (based).
Interpretationnone givenThese participants may have fared worse without the additional CBT received through this study.
“However, these participants may have fared worse without the additional CBT received through this study.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductnone givenAll analyses controlled for baseline values of the respective outcome measure and for treatment condition.
“All analyses controlled for baseline values of the respective outcome measure, as well as treatment condition.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductnone givenAnalyses were repeated using only data from participants who completed the six-month assessment (n = 180).
“Analyses were then repeated using only data from participants who completed the six-month assessment (n = 180).”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
Study design and conductcitationThe PLP and BLP conditions were combined into a single CBT condition for analysis, based on comparative findings from the primary trial.
“we first collapsed the PLP and BLP conditions into a single CBT condition (based on comparative findings in the primary trial – Stanley et al., 2014) to allow comparison of only two treatment arms: CBT vs. UC.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Stanley et al., 2014 source
Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Interpretationnone givenDisparities in socioeconomic arenas such as education, employment status, and income may contribute to differences in uptake of CBT materials between Veteran and community participants.
“Another possibility is that disparities in socioeconomic arenas, such as education, employment status, and income, may contribute to differences in uptake of CBT materials in Veteran and community participants.”
Quote in the paperNot a substantial claimMay combine two claims.
Study design and conductown dataInter-rater agreement was adequate for GAD (kappa = .68), depression (kappa = .91), and other anxiety disorders (kappa = .75).
“Kappa coefficients indicated adequate agreement for GAD (.68), depression (major depression or dysthymia; .91), and other anxiety disorders (.75).”
Quote in the paperNot a substantial claimMay combine two claims.
Study design and conductcitationThe original study design lacked statistical power to test interactions between treatment condition and subsample, and those interactions were very small to small.
“the original study design was not powered to test treatment condition by subsample interactions, which were very small to small”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Stanley et al., 2014 source
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductcitationAmong older primary care adults, the PCL-C shows good internal consistency and convergent validity.
“The PCL-C has good internal consistency and convergent validity among older adults in primary care (Cook, Elhai & Aréan, 2005).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Cook, Elhai & Aréan, 2005 source
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationAPA and NICE endorse CBT as a first-line intervention for GAD.
“endorsement of CBT as a first-line intervention for GAD by the American Psychiatric Association and The United Kingdom’s National Institute for Health and Clinical Excellence as a first-line intervention (APA, 2010; NICE; 2009)”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites APA, 2010
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites NICE; 2009
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataA random fifth of SCID interviews were audio recorded for a second clinician to rate, allowing assessment of inter-rater agreement.
“All SCID interviews were audio taped so that a random 20% could be rated by a second clinician to assess inter-rater agreement.”
Quote in the paperNot a substantial claimMay combine two claims.
Study design and conductcitationAgreement was excellent for the SIGH-A (ICC = .92) and GADSS (ICC = .87).
“intraclass correlation coefficients indicated excellent agreement for the SIGH-A (.92) and GADSS (.87).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataInitial analyses used intent-to-treat methods with multiple imputation to handle missing six-month data.
“Initial analyses included all observations and used intent-to-treat (ITT) methods with multiple imputation procedures (Proc MI and Proc MIANALYZE, SAS Version 9.3) to address missing data at six months.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataThe second author met regularly with evaluators for calibration and rated one tenth of their recorded interviews to estimate inter-rater agreement.
“The second author held regular calibration meetings with the IEs and rated 10% of each IE’s audiotaped interviews to estimate inter-rater agreement.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationUsing a p-value threshold of 0.25 to select variables for multivariable models allows weakly associated variables that may be important collective predictors to be included.
“Using a more conservative p value of < 0.25 to inform which variables should be included in the multivariable predictor models enables variables that could be important collective predictors of an outcome to be simultaneously included in the model even though they are only weakly associated with the outcome in and of themselves (Bendel & Afifi, 1977).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Bendel & Afifi, 1977 source
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductcitationThe SF-12 PCS has adequate reliability and validity in older adults.
“Adequate reliability and validity of the SF-12 PCS have been demonstrated in older adults (Resnick & Nahm, 2001).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Resnick & Nahm, 2001 source
Classified as probably not a substantial claim.
Study design and conductown dataIdentical outcome analyses were performed separately for the Veteran and community samples.
“Identical outcome analyses were conducted separately within the Veteran and community samples.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductnone givenEach provider (PLP and BLP) delivered CBT to both Veteran and community participants.
“Each PLP and BLP delivered CBT to both Veteran and community participants.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductnone givenOther dimensions of social support, such as social connectedness and enacted social support, were not assessed.
“Other dimensions of social support, such as social connectedness (the quantity and quality of interpersonal relationships) and enacted social support (specific supportive actions), were not assessed.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationThese other dimensions of social support may interact with perceived social support in predicting distress.
“However, these may interact with perceived social support in predicting distress (Wethington & Kessler, 1986).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Wethington & Kessler, 1986 source
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationVeterans with complex psychiatric and social service needs may benefit from a combination of CBT and case management, an approach shown to benefit impoverished older adults with depression.
“Alternatively, Veterans with complex psychiatric and social service needs (e.g., unemployment, homelessness) may benefit from a combination of CBT and case management, an approach shown to benefit impoverished older adults with depression (Areán et al., 2005; 2010).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Areán et al., 2005; 2010
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
The paper relies on this without support.
Before this study, no CBT outcome trial had enrolled both Veteran and community participants together.
“Although no CBT outcome studies have included both Veteran and community participants within the same trial”
“To our knowledge this trial is the first study of CBT for anxiety to include both community and Veteran participants”
The paper relies on this without support.
Few studies have reported predictors of CBT outcomes among Veterans.
“few studies report predictors of CBT outcomes among Veterans.”
The paper relies on this without support.
VA has not issued clinical guidelines for treating GAD.
“the Department of Veterans Affairs has not yet published clinical practice guidelines for the treatment of GAD”
The paper relies on this without support.
Just one RCT of CBT for GAD had previously enrolled Veterans.
“only a single randomized controlled trial of CBT for GAD recently published by our group has included a Veteran sample.”
The paper relies on this without support.
GAD is understudied in Veteran samples.
“Understudied in Veteran samples”
The paper relies on this without support.
This is the first study to include Veteran and community participants within a single CBT trial.
“This is the first study to include Veteran and community participants within a single CBT trial, allowing examination of differences in treatment outcome.”
The paper relies on this without support.
This was the first trial of CBT for GAD to include Veterans.
“This was the first trial of CBT for GAD to include Veterans, and, given our findings suggesting that Veterans may show smaller treatment effects with a standard CBT package than community participants, future work should identify how to better adapt CBT protocols for Veteran populations.”
The paper relies on this without support.
The majority of CBT studies within Veteran samples have been conducted with Vietnam Veterans.
“The Veterans included in this study were primarily of the Vietnam era; and, in fact, the majority of CBT studies within Veteran samples have been conducted with Vietnam Veterans.”
Statistics recomputed
Every reported test result, recomputed from its test statistic and degrees of freedom. A result shows as not adding up only once an independent check has confirmed it.
- Consistentχ²(1) = 0.74reported p = .39 · recomputed p = .390
“χ2(1) = 0.74, p = .39”
- Consistentχ²(1) = 1.31reported p = .25 · recomputed p = .252
“χ2(1) = 1.31, p = .25”
- Consistentχ²(1) = 0.09reported p = .76 · recomputed p = .764
“χ2(1) = 0.09, p = .76”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Completer sample size conflicts with dropout counts
MajorOne passage says 21 Veterans and 14 community participants dropped out of the 223 randomized participants, implying 188 completers. Another passage explicitly says the completer analyses used n = 180, which contradicts that arithmetic.
“Of the 223 randomized participants, 21 Veterans (22%) and 14 community participants (17%) did not complete the 6 month assessment and were considered dropouts.”
“Analyses were then repeated using only data from participants who completed the six-month assessment (n = 180).”
Community dropout percentage does not match enrollment
MinorThe paper reports 122 enrolled community participants. Fourteen dropouts among 122 participants is 11.5%, not the stated 17%.
Reported 17 · recomputed 11.47541
“Of the 223 randomized participants, 21 Veterans (22%) and 14 community participants (17%) did not complete the 6 month assessment and were considered dropouts.”
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Sensitivity and False Alarm Rate of a Fall Sensor in Long-Term Fall Detection in the Elderly
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Development and validation of the Penn State Worry Questionnaire
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Psychometric Characteristics of the Multidimensional Scale of Perceived Social Support
Zimet, G. D., Powell, S. S., Farley, G. K., Werkman, S., & Berkoff, K. A. (1990) · Journal of Personality Assessment · doi:10.1080/00223891.1990.9674095 · Cited by 4,855 · see citing works
A Multidimensional Meta-Analysis of Psychotherapy for PTSD
Bradley, R., Greene, J., Russ, E., Dutra, L., & Westen, D. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.2.214 · Cited by 1,938 · see citing works
Perceived support, received support, and adjustment to stressful life events
Wethington, E., & Kessler, R. C. (1986) · Journal of Health and Social Behavior · doi:10.2307/2136504 · Cited by 1,431 · cited 1× · see citing works
“However, these may interact with perceived social support in predicting distress (Wethington & Kessler, 1986).”
BackgroundPRACTICE GUIDELINE FOR THE Treatment of Patients With Major Depressive Disorder
Gelenberg, A. J., Freeman, P. B., Markowitz, J. C., Rosenbaum, J. F., Thase, M. E., Trivedi, M. H., & Rhoads, R. S. (2010) · Cited by 1,372 · see citing works
Bisson, J. I., Ehlers, A., Matthews, R., Pilling, S., Richards, D., & Turner, S. (2007) · British Journal of Psychiatry · doi:10.1192/bjp.bp.106.021402 · Cited by 900 · cited 2× · see citing works
“…of CBT for PTSD found smaller treatment effect sizes for Veteran samples than for non-Veteran samples (Barrera, Mott, Hofstein, & Teng, 2013; Bisson et al., 2007; Bradley, Greene, Russ, Dutra, & Westen, 2005), and a randomized controlled trial comparing CBT for depression to treatment as…”
BackgroundComparison of Stopping Rules in Forward “Stepwise” Regression
Bendel, R. B., & Afifi, A. A. (1977) · Journal of the American Statistical Association · doi:10.1080/01621459.1977.10479905 · Cited by 885 · cited 1× · see citing works
“…which variables should be included in the multivariable predictor models enables variables that could be important collective predictors of an outcome to be simultaneously included in the model even though they are only weakly associated with the outcome in and of themselves (Bendel & Afifi, 1977).”
BackgroundBorkovec, T. D., & Costello, E. (1993) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.61.4.611 · Cited by 756 · cited 1× · see citing works
“The CBT protocol utilized in this study is based on elements of prior CBT protocols for GAD in younger adults (Borkovec & Costello, 1993; Craske, Barlow, & O’Leary, 1992) and modified to include a flexible delivery format to meet the needs of older adults in primary care medical settings (Stanley,…”
MethodAre Patients at Veterans Affairs Medical Centers Sicker?
Agha, Z., Lofgren, R. P., VanRuiswyk, J. V., & Layde, P. M. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.21.3252 · Cited by 744 · cited 2× · see citing works
“This difference was not statistically significant (χ2(1) = 0.”
BackgroundPsychological treatment of generalized anxiety disorder: A meta-analysis
Cuijpers, P., Sijbrandij, M., Koole, S., Huibers, M., Berking, M., & Andersson, G. (2014) · Clinical Psychology Review · doi:10.1016/j.cpr.2014.01.002 · Cited by 527 · cited 1× · see citing works
“Cognitive-behavioral therapy (CBT) is an evidence-based treatment for GAD and has demonstrated efficacy in both younger and older adult civilian populations (Cuijpers et al., 2014).”
BackgroundPTSD Checklist—Civilian Version
Weathers, F. W., Litz, B., Herman, D., Juska, J., & Keane, T. (2012) · PsycTESTS Dataset · doi:10.1037/t02622-000 · Cited by 527 · see citing works
Efficacy of peer support interventions for depression: a meta-analysis
Pfeiffer, P. N., Heisler, M., Piette, J. D., Rogers, M. A. M., & Valenstein, M. (2011) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2010.10.002 · Cited by 484 · see citing works
Shear, M. K., Vander Bilt, J., Rucci, P., Endicott, J., Lydiard, B., Otto, M. W., Pollack, M. H., Chandler, L., Williams, J., Ali, A., et al. (2001) · Depression and Anxiety · doi:10.1002/da.1033 · Cited by 483 · see citing works
Campbell, D. G., Felker, B. L., Liu, C.-F., Yano, E. M., Kirchner, J. E., Chan, D., Rubenstein, L. V., & Chaney, E. F. (2007) · Journal of General Internal Medicine · doi:10.1007/s11606-006-0101-4 · Cited by 458 · cited 1× · see citing works
“…Veterans (Mohr et al., 2011; Selim et al., 2004), higher rates of psychiatric and medical comorbidity (Agha, Lofgren, Van Ruiswyk, & Layde; 2000; Campbell et al., 2007), lack of social support (Tsai, Harpaz-Rotem, Pietrzak, & Southwick, 2012; Pietrzak & Cook; 2013), and, although…”
BackgroundEffectiveness of national implementation of prolonged exposure therapy in Veterans affairs care
Eftekhari, A., Ruzek, J. I., Crowley, J. J., Rosen, C. S., Greenbaum, M. A., & Karlin, B. E. (2013) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2013.36 · Cited by 338 · cited 1× · see citing works
“Previous studies examining treatment outcome for PTSD between Veteran cohorts suggest poorer treatment outcome in Vietnam-era Veterans than in returning Veterans from the wars in Iraq and Afghanistan (Chard, Schumm, Owens, & Cottingham, 2010; Eftekhari et al., 2013; but see Yoder et al., 2012).”
ResultA randomized trial of telemedicine-based collaborative care for depression
Fortney, J. C., Pyne, J. M., Edlund, M. J., Williams, D. K., Robinson, D. E., Mittal, D., & Henderson, K. L. (2007) · Journal of General Internal Medicine · doi:10.1007/s11606-007-0201-9 · Cited by 315 · cited 1× · see citing works
“Similarly, a study of telemedicinebased collaborative care for depression in Veterans (Fortney et al., 2007) found smaller effect sizes for symptom improvement than a similar study of telemedicine-based collaborative care in patients from federally qualified health centers (Fortney et al., 2013).”
BackgroundFortney, J. C., Pyne, J. M., Mouden, S. B., Mittal, D., Hudson, T. J., Schroeder, G. W., Williams, D. K., Bynum, C. A., Mattox, R., & Rost, K. M. (2013) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2012.12050696 · Cited by 296 · see citing works
Risk factors for the development versus maintenance of posttraumatic stress disorder
Schnurr, P. P., Lunney, C. A., & Sengupta, A. (2004) · Journal of Traumatic Stress · doi:10.1023/b:jots.0000022614.21794.f4 · Cited by 275 · see citing works
Hopko, D. R., Reas, D. L., Beck, J. G., Stanley, M. A., Wetherell, J. L., Novy, D. M., & Averill, P. M. (2003) · Psychological Assessment · doi:10.1037/1040-3590.15.2.173 · Cited by 271 · see citing works
Self-citationBoscarino, J. A. (1995) · Journal of Traumatic Stress · doi:10.1007/bf02109567 · Cited by 260 · cited 2× · see citing works
“The Veterans included in this study were primarily of the Vietnam era; and, in fact, the majority of CBT studies within Veteran samples have been conducted with Vietnam Veterans.”
BackgroundReliability and validity testing of the revised 12-item Short-Form Health Survey in older adults
Resnick, B., & Nahm, E. S. (2001) · Journal of Nursing Measurement · doi:10.1891/1061-3749.9.2.151 · Cited by 255 · cited 1× · see citing works
“Adequate reliability and validity of the SF-12 PCS have been demonstrated in older adults (Resnick & Nahm, 2001).”
BackgroundTsai, J., Harpaz-Rotem, I., Pietrzak, R. H., & Southwick, S. M. (2012) · Psychiatry: Interpersonal and Biological Processes · doi:10.1521/psyc.2012.75.2.135 · Cited by 255 · see citing works
Stanley, M. A., Wilson, N. L., Novy, D. M., Rhoades, H. M., Wagener, P. D., Greisinger, A. J., Cully, J. A., & Kunik, M. E. (2009) · JAMA · doi:10.1001/jama.2009.458 · Cited by 247 · cited 2× · see citing works
“The PSWQ-A is useful for identifying GAD in older primary care patients (Webb et al., 2008), is capable of demonstrating change following treatment (Stanley et al., 2009; Shrestha et al., 2012), and is advantageous for older adults because of its brevity and simplicity (Hopko, et al 2003).”
MethodSelf-citationCognitive-behavioral treatment of late-life generalized anxiety disorder
Stanley, M. A., Beck, J. G., Novy, D. M., Averill, P. M., Swann, A. C., Diefenbach, G. J., & Hopko, D. R. (2003) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.71.2.309 · Cited by 247 · cited 1× · see citing works
“This protocol has demonstrated efficacy in prior trials of CBT for late-life GAD in primary care (Calleo et al., 2013; Stanley et al., 2003, 2009).”
MethodSelf-citationPietrzak, R. H., & Cook, J. M. (2013) · Depression and Anxiety · doi:10.1002/da.22083 · Cited by 215 · see citing works
Assessment of anxiety in older adults: A systematic review of commonly used measures
Therrien, Z., & Hunsley, J. D. (2011) · Aging & Mental Health · doi:10.1080/13607863.2011.602960 · Cited by 204 · cited 1× · see citing works
“The STAI-T is a 20-item measure of general anxiety, used commonly in studies of older adults (Therrien & Hunsley, 2012).”
MethodRazykov, I., Ziegelstein, R. C., Whooley, M. A., & Thombs, B. D. (2012) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2012.06.001 · Cited by 188 · see citing works
A comparison of OEF and OIF Veterans and Vietnam Veterans receiving cognitive processing therapy
Chard, K. M., Schumm, J. A., Owens, G. P., & Cottingham, S. M. (2010) · Journal of Traumatic Stress · doi:10.1002/jts.20500 · Cited by 175 · see citing works
Psychometric properties of the MSPSS in older adults
STANLEY, M. A., BECK, J. G., & ZEBB, B. J. (1998) · Aging & Mental Health · doi:10.1080/13607869856669 · Cited by 161 · see citing works
Self-citationThe health status of elderly Veteran enrollees in the Veterans Health Administration
Selim, A. J., Berlowitz, D. R., Fincke, G., Cong, Z., Rogers, W., Haffer, S. C., Ren, X. S., Lee, A., Qian, S. X., Miller, D. R., et al. (2004) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2004.52355.x · Cited by 119 · cited 2× · see citing works
“Potential explanations for Veterans’ poorer treatment response include greater chronicity and symptom severity among Veterans (Mohr et al., 2011; Selim et al., 2004), higher rates of psychiatric and medical comorbidity (Agha, Lofgren, Van Ruiswyk, & Layde; 2000; Campbell et al., 2007), lack of…”
BackgroundBarrera, T. L., Mott, J. M., Hofstein, R. F., & Teng, E. J. (2013) · Clinical Psychology Review · doi:10.1016/j.cpr.2012.09.005 · Cited by 103 · see citing works
Self-citationFrueh, B. C., Grubaugh, A. L., Elhai, J. D., & Buckley, T. C. (2007) · American Journal of Public Health · doi:10.2105/ajph.2007.115436 · Cited by 103 · cited 1× · see citing works
“…& Layde; 2000; Campbell et al., 2007), lack of social support (Tsai, Harpaz-Rotem, Pietrzak, & Southwick, 2012; Pietrzak & Cook; 2013), and, although controversial, the potential for reinforcement of symptom maintenance through the VHA service-connected disability program (Frueh et al., 2007).”
BackgroundPsychometric properties of the PTSD Checklist with older primary care patients
Cook, J. M., Elhai, J. D., & Areán, P. A. (2005) · Journal of Traumatic Stress · doi:10.1002/jts.20038 · Cited by 101 · see citing works
Yoder, M., Tuerk, P. W., Price, M., Grubaugh, A. L., Strachan, M., Myrick, H., & Acierno, R. (2012) · Psychological Services · doi:10.1037/a0026279 · Cited by 96 · cited 1× · see citing works
“Previous studies examining treatment outcome for PTSD between Veteran cohorts suggest poorer treatment outcome in Vietnam-era Veterans than in returning Veterans from the wars in Iraq and Afghanistan (Chard, Schumm, Owens, & Cottingham, 2010; Eftekhari et al., 2013; but see Yoder et al., 2012).”
ResultStanley, M. A., Wilson, N. L., Amspoker, A. B., Kraus-Schuman, C., Wagener, P. D., Calleo, J. S., Cully, J. A., Teng, E., Rhoades, H. M., Williams, S., et al. (2014) · Depression and Anxiety · doi:10.1002/da.22239 · Cited by 96 · cited 5× · see citing works
“Method 2.1 Participants Detailed information about study design and recruitment is reported in Stanley et al. (2014).”
BackgroundMethodResultInfluentialSelf-citationTreatment of depression in low-income older adults
Areán, P. A., Gum, A., McCulloch, C. E., Bostrom, A., Gallagher-Thompson, D., & Thompson, L. (2005) · Psychology and Aging · doi:10.1037/0882-7974.20.4.601 · Cited by 90 · cited 1× · see citing works
“Alternatively, Veterans with complex psychiatric and social service needs (e.g., unemployment, homelessness) may benefit from a combination of CBT and case management, an approach shown to benefit impoverished older adults with depression (Areán et al., 2005; 2010).”
BackgroundTreatment of posttraumatic stress disorder in U.S. combat Veterans: a meta-analytic review
Goodson, J., Helstrom, A., Halpern, J. M., Ferenschak, M. P., Gillihan, S. J., & Powers, M. B. (2011) · Psychological Reports · doi:10.2466/02.09.15.16.pr0.109.5.573-599 · Cited by 90 · cited 1× · see citing works
“…the greater psychiatric symptom severity, poorer physical health status, and higher rates of psychiatric comorbidity among the Veteran sample support previous assertions that Veterans tend to have more chronic and severe presentations than non-Veterans (Goodson et al., 2011; Selim et al., 2004).”
BackgroundBrenes, G. A., Miller, M. E., Williamson, J. D., McCall, W. V., Knudson, M., & Stanley, M. A. (2012) · The American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e31822ccd3e · Cited by 77 · cited 1× · see citing works
“The SIGH-A is a 14-item measure with demonstrated sensitivity to change in clinical trials (Brenes et al., 2012).”
BackgroundSelf-citationGeneralized anxiety disorder severity scale (GADSS): a preliminary validation study
Shear, K. M., Belnap, B. H., Mazumdar, S., Houck, P. R., & Rollman, B. L. (2006) · Depression and Anxiety · doi:10.1002/da.20149 · Cited by 73 · see citing works
Monitoring the dissemination of peer support in the VA Healthcare System
Barber, J. A., Rosenheck, R. A., Armstrong, M., & Resnick, S. G. (2008) · Community Mental Health Journal · doi:10.1007/s10597-008-9146-7 · Cited by 68 · see citing works
Milanak, M. E., Gros, D. F., Magruder, K. M., Brawman-Mintzer, O., & Frueh, B. C. (2013) · Psychiatry Research · doi:10.1016/j.psychres.2013.03.031 · Cited by 62 · see citing works
Stanley, M. A., Diefenbach, G. J., & Hopko, D. R. (2004) · Behavior Modification · doi:10.1177/0145445503259259 · Cited by 54 · see citing works
Self-citationTreating depression in disabled, low‐income elderly: a conceptual model and recommendations for care
Areán, P. A., Mackin, S. R., Vargas‐Dwyer, E., Raue, P. J., Sirey, J. A., Kanellopolos, D., & Alexopoulos, G. S. (2010) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.2556 · Cited by 53 · cited 1× · see citing works
“Alternatively, Veterans with complex psychiatric and social service needs (e.g., unemployment, homelessness) may benefit from a combination of CBT and case management, an approach shown to benefit impoverished older adults with depression (Areán et al., 2005; 2010).”
BackgroundMohr, D. C., Carmody, T., Erickson, L., Jin, L., & Leader, J. (2011) · Journal of Consulting and Clinical Psychology · doi:10.1037/a0022395 · Cited by 50 · cited 1× · see citing works
“Potential explanations for Veterans’ poorer treatment response include greater chronicity and symptom severity among Veterans (Mohr et al., 2011; Selim et al., 2004), higher rates of psychiatric and medical comorbidity (Agha, Lofgren, Van Ruiswyk, & Layde; 2000; Campbell et al., 2007), lack of…”
BackgroundFletcher, T. L., Mott, J. M., Hundt, N. E., Mignogna, J., Yu, H., Stanley, M. A., & Cully, J. A. (2013) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2013.10.013 · Cited by 45 · cited 1× · see citing works
“…GAD among Veterans in the Veterans Health Administration (VHA) system (more than 22,000 Veterans were newly diagnosed with GAD in fiscal year 2012; Barrera et al., 2014), the Department of Veterans Affairs has not yet published clinical practice guidelines for the treatment of GAD and only a…”
BackgroundSelf-citationGeneralized Anxiety Disorder Severity Scale validation in older adults
Andreescu, C., Belnap, B. H., Rollman, B. L., Houck, P., Ciliberti, C., Mazumdar, S., Shear, M. K., & Lenze, E. J. (2008) · The American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e31817c6aab · Cited by 35 · cited 1× · see citing works
“…GAD severity was rated with the Generalized Anxiety Disorder Severity Scale (GADSS; Shear, Belnap, Mazumdar, Houck, & Rollman, 2006), a six-item measure that assesses DSM-IV criteria and has adequate psychometric properties among older adults (Andreescu et al., 2008; Weiss et al., 2009).”
MethodJain, S., McLean, C., & Rosen, C. S. (2012) · Military Medicine · doi:10.7205/milmed-d-11-00401 · Cited by 34 · see citing works
Predictors of CBT outcome in older adults with GAD
Hundt, N. E., Amspoker, A. B., Kraus-Schuman, C., Cully, J. A., Rhoades, H., Kunik, M. E., & Stanley, M. A. (2014) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2014.09.012 · Cited by 33 · cited 1× · see citing works
“…data from the two CBT conditions found that subsample (community vs. Veteran participants) was a predictor of treatment response, such that community participants receiving CBT showed greater improvements in anxiety and worry symptoms than Veteran participants receiving CBT (Hundt et al., 2014).”
ResultSelf-citationComparison of Self-report Measures for Identifying Late-life Generalized Anxiety in Primary Care
Webb, S. A., Diefenbach, G., Wagener, P., Novy, D. M., Kunik, M., Rhoades, H. M., & Stanley, M. A. (2008) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988708324936 · Cited by 32 · cited 1× · see citing works
“The PSWQ-A is useful for identifying GAD in older primary care patients (Webb et al., 2008), is capable of demonstrating change following treatment (Stanley et al., 2009; Shrestha et al., 2012), and is advantageous for older adults because of its brevity and simplicity (Hopko, et al 2003).”
MethodSelf-citationSpoont, M. R., Sayer, N. A., Nelson, D. B., & Nugent, S. M. (2007) · Military Medicine · doi:10.7205/milmed.172.6.572 · Cited by 25 · see citing works
Weiss, B. J., Calleo, J., Rhoades, H. M., Novy, D. M., Kunik, M. E., Lenze, E. J., & Stanley, M. A. (2009) · Depression and Anxiety · doi:10.1002/da.20520 · Cited by 18 · cited 1× · see citing works
“…GAD severity was rated with the Generalized Anxiety Disorder Severity Scale (GADSS; Shear, Belnap, Mazumdar, Houck, & Rollman, 2006), a six-item measure that assesses DSM-IV criteria and has adequate psychometric properties among older adults (Andreescu et al., 2008; Weiss et al., 2009).”
MethodSelf-citationTreating Late-Life Generalized Anxiety Disorder in Primary Care: An Effectiveness Pilot Study
Calleo, J. S., Bush, A. L., Cully, J. A., Wilson, N. L., Kraus-Schuman, C., Rhoades, H. M., Novy, D. M., Masozera, N., Williams, S., Horsfield, M., et al. (2013) · Journal of Nervous & Mental Disease · doi:10.1097/nmd.0b013e31828e0fd6 · Cited by 17 · cited 1× · see citing works
“This protocol has demonstrated efficacy in prior trials of CBT for late-life GAD in primary care (Calleo et al., 2013; Stanley et al., 2003, 2009).”
MethodSelf-citationPilot Findings from a Community-based Treatment Program for Late-Life Anxiety
Shrestha, S., Armento, M. E. A., Bush, A. L., Huddleston, C., Zeno, D., Jameson, J., Evans-Hudnall, G. L., Harris, T., Scott-Gurnell, K., Kunik, M., et al. (2012) · doi:10.5750/ijpcm.v2i3.130 · Cited by 14
Self-citationBoscarino, J. A. (1995) · Journal of Traumatic Stress · doi:10.1002/jts.2490080211
Flagged first, then by citations
3 of the 67 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Hall, J., Kellett, S., Berrios, R., Bains, M. K., & Scott, S. (2016) · The American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2016.06.006 · Cited by 157 · see citing works
Brenes, G. A., Danhauer, S. C., Lyles, M. F., Hogan, P. E., & Miller, M. E. (2015) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2015.1154 · Cited by 143 · see citing works
Long-Term Effects of Telephone-Delivered Psychotherapy for Late-Life GAD
Brenes, G. A., Danhauer, S. C., Lyles, M. F., Anderson, A., & Miller, M. E. (2017) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2017.05.013 · Cited by 71 · see citing works
Toward Robust Anxiety Biomarkers: A Machine Learning Approach in a Large-Scale Sample
Boeke, E. A., Holmes, A. J., & Phelps, E. A. (2020) · Biological Psychiatry: Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2019.05.018 · Cited by 50 · see citing works
Evidence Review—Social Determinants of Health for Veterans
Duan‐Porter, W., Martinson, B. C., Greer, N. L., Taylor, B. C., Ullman, K. E., McKenzie, L. G., Rosebush, C. E., MacDonald, R. H., Falde, S., & Wilt, T. J. (2018) · Journal of General Internal Medicine · doi:10.1007/s11606-018-4566-8 · Cited by 38 · see citing works
Gobin, R. L., Mackintosh, M., Willis, E. A., Allard, C. B., Kloezeman, K. C., & Morland, L. A. (2017) · Psychological Trauma Theory Research Practice and Policy · doi:10.1037/tra0000266 · Cited by 36 · see citing works
“, 2015), depression (Hundt, Barrera, Robinson, & Cully, 2014), and generalized anxiety disorder (Barrera et al., 2015).”
BackgroundAmati, F., Banks, C., Greenfield, G., & Green, J. (2017) · Journal of Public Health · doi:10.1093/pubmed/fdx168 · Cited by 35 · see citing works
Brenes, G. A., Divers, J., Miller, M. E., Anderson, A., Hargis, G., & Danhauer, S. C. (2020) · Depression and Anxiety · doi:10.1002/da.23107 · Cited by 27 · see citing works
“A scores (Barrera et al., 2015; Roseman et al., 2011; Stanley et al., 2009), a 3‐point decrease in PROMIS‐Anxiety T‐Scores (Kroenke et al., 2019), and a 6‐point decrease in ISI scores from baseline to postintervention (Yang et al., 2009).”
BackgroundThakur, E. R., Sansgiry, S., Petersen, N. J., Stanley, M. A., Kunik, M. E., Naik, A. D., & Cully, J. A. (2017) · International Journal of Behavioral Medicine · doi:10.1007/s12529-017-9663-2 · Cited by 24 · see citing works
Self-citationFreshour, J. S., Amspoker, A. B., Yi, M., Kunik, M. E., WILSON, N. L., Kraus-Schuman, C. A., Cully, J. A., Teng, E. J., Williams, S., Masozera, N., et al. (2016) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.4431 · Cited by 22 · see citing works
Self-citationLee, A. A., Sripada, R. K., Hale, A. C., Ganoczy, D. A., TRIVEDI, R. B., Arnow, B. A., & Pfeiffer, P. N. (2021) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000645 · Cited by 20 · see citing works
Fletcher, T. L., Boykin, D. M., Helm, A., Dawson, D. B., Ecker, A. H., Freshour, J., Teng, E., Lindsay, J., & Hundt, N. E. (2022) · Military Psychology · doi:10.1080/08995605.2021.1970983 · Cited by 19 · see citing works
“Psychotherapy trials for other disorders in Veterans often show attenuated effect sizes compared to civilian populations (Barrera et al., 2015; Hundt, Barrera, Robinson, & Cully, 2014), underscoring the impact of the large treatment effects for OCD and PTSD in the current study.”
BackgroundSelf-citationHendriks, G., Janssen, N., Robertson, L., van Balkom, A. J. L. M., van Zelst, W. H., Wolfe, S., Voshaar, R. C. O., & Uphoff, E. (2024) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007674.pub3 · Cited by 20 · see citing works
Long-Term Effects of Cognitive-Behavioral Therapy and Yoga for Worried Older Adults
Danhauer, S. C., Miller, M. E., Divers, J., Anderson, A., Hargis, G., & Brenes, G. A. (2022) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2022.02.002 · Cited by 13 · see citing works
Huddleston, C., Martin, L., Woods, K., & Dindo, L. (2018) · Military Medicine · doi:10.1093/milmed/usx090 · Cited by 11 · see citing works
Ding, H., Li, J., Chen, Y., et al. (2020) · World Journal of Surgical Oncology · doi:10.1186/s12957-020-1801-7 · Cited by 11 · see citing works
“Therefore, we believe that, in addition to guiding patients with regular anal function exercise, it is also important to give patients more humanistic care, help them to strengthen their understanding [32] and acceptance [19] of their own condition, and establish a more positive and optimistic attitude toward diagnosi…”
BackgroundJohnco, C. J., Wuthrich, V. M., Brenes, G. A., Wetherell, J. L., & Mohlman, J. (2021) · International Psychogeriatrics · doi:10.1017/s1041610221000351 · Cited by 9 · see citing works
Grubbs, K. M., Fortney, J. C., Pyne, J. M., D, D. M. M., Ray, J., & Hudson, T. J. (2018) · Psychiatric Services · doi:10.1176/appi.ps.201700067 · Cited by 10 · see citing works
“Veteran status is an important dimension to explore because emerging research suggests that veterans may experience more treatment-resistant mental health problems (11,12) and a poorer response to psychotherapy (13,14).”
BackgroundMcIngvale, E., Kirk, N. P. V., Amspoker, A. B., Stanley, M. A., & Fletcher, T. L. (2019) · Journal of Cognitive Psychotherapy · doi:10.1891/0889-8391.33.1.11 · Cited by 9 · see citing works
Self-citationGuided Self-Management Targeting Anxiety and Activity Participation in Older Veterans
Gould, C., Carlson, C., Wetherell, J., O'Hara, R., Goldstein, M., Loup, J., Ma, F., & Beaudreau, S. (2020) · Aging & Mental Health · doi:10.1080/13607863.2020.1758905 · Cited by 6 · see citing works
“This finding dovetails with findings of diminished effects of CBT for anxiety found in Veterans compared with non-Veterans (Barrera et al., 2015).”
ResultSchmidt, A., Grey, N., Strauss, C., & Gaysina, D. (2024) · Clinical Psychology Review · doi:10.1016/j.cpr.2024.102463 · Cited by 9 · see citing works
Obsessive-Compulsive Disorder in Veterans: An Introduction to the Special Issue
Fletcher, T. L. (2019) · Journal of Cognitive Psychotherapy · doi:10.1891/0889-8391.33.1.4 · Cited by 3 · see citing works
“Underscoring the need for empirical examination of the treatment of OCD in veterans is research indicating that veterans’ response to cognitive behavioral treatment for other disorders, including PTSD, anxiety, and depression, may be less robust than civilians’ (Barrera, Mott, Hoftstein, & Teng, 2013; Barrera et al.,…”
BackgroundSelf-citationKelso, K. C., & Grös, D. F. (2024) · Journal of Psychopathology and Behavioral Assessment · doi:10.1007/s10862-024-10157-w · Cited by 1 · see citing works
“This may be especially important for veterans who struggle with IU and RNT. IU predicts symptom severity among veterans with emotional disorders (Hunt et al., 2022) and they report smaller reductions in RNT following treatment relative to civilians (Barrera et al., 2015; Hundt et al., 2014).”
Wuthrich, V. M., Huang-Smith, T., Rapee, R. M., Kangas, M., & Jones, M. (2026) · Cognitive Therapy and Research · doi:10.1007/s10608-025-10703-0 · Cited by 1 · see citing works
Siffert, V., Riahi, C., Stanley, M. A., & Fletcher, T. L. (2019) · Journal of Cognitive Psychotherapy · doi:10.1891/0889-8391.33.1.71 · Cited by 1 · see citing works
“Given that veterans often respond differently to psychotherapy interventions than civilians do (Barrera et al., 2015; Barrera, Mott, Hofstein, & Teng, 2013; Hundt, Barrera, Robinson, & Cully, 2014), and also face many logistic and stigma-related barriers to engaging in mental health care (Hundt, et al.”
BackgroundSelf-citationWozniak, E. E., Hare, D. J., Gregg, L., & Wittkowski, A. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1424010 · Cited by 2 · see citing works
Obsessive-Compulsive Disorder Among Veterans: Discussion and Future Directions
Stanley, M. A. (2019) · Journal of Cognitive Psychotherapy · doi:10.1891/0889-8391.33.1.8
“As noted in the introduction to this special issue, clinical trials of other disorders suggest treatments effective for mental health conditions in civilians are not always effective for veterans (e.g., Barrera et al., 2015; Mohr, Carmody, Erickson, Jin, & Leader, 2011).”
BackgroundSelf-citationPonzini, G. T., Hundt, N. E., Christie, I. C., Chen, P. V., Ecker, A. H., Lindsay, J. A., Teng, E. J., Storch, E. A., Myers, U. S., Roussev, M. S., et al. (2024) · Contemporary Clinical Trials · doi:10.1016/j.cct.2024.107445
Self-citation
- Authors
- Barrera, T. L., Cully, J. A., Amspoker, A. B., Wilson, N. L., Kraus-Schuman, C., Wagener, P. D., Calleo, J. S., Teng, E. J., Rhoades, H. M., Masozera, N., Kunik, M. E., & Stanley, M. A.
- Affiliations
- Michael E. DeBakey VA Medical Center (US)
- The University of Texas Health Science Center at Houston (US)
- Venue
- Journal of Anxiety Disorders
- Publisher
- Elsevier BV
- Published
- 2015-06
- Volume
- 33
- Pages
- 72-80
- ISSN
- 0887-6185 (ISSN-L)
- PMC
- PMC4479977
- OpenAlex
- W236121655
- Cited by
- 28
- References
- 67
- Citations by year
- 2026: 1 · 2024: 5 · 2022: 1 · 2021: 3 · 2020: 3 · 2019: 5 · 2018: 3 · 2017: 4 · 2016: 2 · 2015: 1
- FWCI
- 5.02
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Anxiety Disorders (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (MH053932)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Assessments
- Keywords
- cognitive behavioral therapy, late-life anxiety, generalized anxiety disorder, veterans, community sample, treatment effect heterogeneity, perceived social support, psychiatric comorbidity, usual care, older adults
- MeSH terms
- Aged, Anxiety Disorders, Depressive Disorder, Female, Humans, Male, Patient Acceptance of Health Care, Social Support, Veterans, Cognitive Behavioral Therapy, Treatment Outcome
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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