National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

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Items 401–500 of 1,029

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2. A critical review of chronic traumatic encephalopathy
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3. Comparison of ¹⁸F‐florbetaben quantification results using the standard Centiloid, MR‐based, and MR‐less CapAIBL^® approaches: Validation against histopathology
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4. β-Amyloid PET and neuropathology in dementia with Lewy bodies
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5. Contribution of mixed pathology to medial temporal lobe atrophy in Alzheimer's disease
   Robin de Florès, Laura E.M. Wisse, Sandhitsu R. Das, Long Xie, Corey T. McMillan, John Q. Trojanowski, John L. Robinson, Murray Grossman, Edward B. Lee, David John Irwin et al. · 2020 · Alzheimer s & Dementia
6. Inflammatory Cascade in Alzheimer’s Disease Pathogenesis: A Review of Experimental Findings
   Jade de Oliveira, Ewa Kucharska, Michelle Lima Garcez, Matheus Scarpatto Rodrigues, João Quevedo, Inés Moreno‐González, Josiane Budni · 2021 · Cells
7. Patterns of microglial cell activation in frontotemporal lobar degeneration
   Lant, Suzannah B., Robinson, Andrew C., Thompson, Jennifer C., Rollinson, Sara, Pickering‐Brown, Stuart, Snowden, Julie S., Davidson, Yvonne S., Gerhard, Alexander, Mann, David M. A. · 2014 · Neuropathology and Applied Neurobiology
8. CSF β-Amyloid 1-42 Predicts Progression to Cognitive Impairment in Newly Diagnosed Parkinson Disease
   Mark Terrelonge, Karen S. Marder, Daniel A. Weintraub, Roy N. Alcalay · 2015 · Journal of Molecular Neuroscience
9. Pathogenesis and Disease-modifying Therapy in Alzheimer's Disease: The Flat Line of Progress
   Rudy J. Castellani, George L. Perry · 2012 · Archives of Medical Research
10. Capillary cerebral amyloid angiopathy in Alzheimer’s disease: association with allocortical/hippocampal microinfarcts and cognitive decline
    M. Hecht, Lara Maria Krämer, Christine Arnim, M. Otto, D. Thal · 2018 · Acta Neuropathologica
11. NIA commentary on the NIA‐AA Research Framework: Towards a biological definition of Alzheimer's disease
    Nina B. Silverberg, Cerise L. Elliott, Laurie M. Ryan, Eliezer Masliah, Richard J. Hodes · 2018 · Alzheimer s & Dementia
12. Characteristics of Tau and Its Ligands in PET Imaging
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13. Cryptic exon incorporation occurs in Alzheimer’s brain lacking TDP-43 inclusion but exhibiting nuclear clearance of TDP-43
    Mingkuan Sun, William Bell, Katherine D. LaClair, Jonathan P. Ling, Heather Han, Yusuke Kageyama, Olga Pletniková, Juan Carlos Troncoso, Philip C. Wong, Liam L. Chen · 2017 · Acta Neuropathologica
14. Differentiation of Alzheimer's disease based on local and global parameters in personalized Virtual Brain models
    Joelle Zimmermann, Alistair Perry, Michael J Breakspear, Michael Schirner, Perminder Singh Sachdev, W. Wen, Nicole A. Kochan, M. Mapstone, Petra Ritter, Anthony Randal McIntosh et al. · 2018 · NeuroImage Clinical
15. Protein Expression of Angiotensin-Converting Enzyme 2 (ACE2) is Upregulated in Brains with Alzheimer’s Disease
    Qiyue Ding, Nataliia V. Shults, Sergiy G. Gychka, Brent T. Harris, Yuichiro Suzuki · 2021 · International Journal of Molecular Sciences
16. Blood phosphorylated tau for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis
    Joseph Therriault, Wagner Scheeren Brum, Lydia Trudel, Arthur C. Macedo, Fernando Valentim Bitencourt, Carolina Castro Martins, Martin Nakouzi, Ilaria Pola, Matthew Wai Kin Wong, Przemysław Radosław Kac et al. · 2025 · The Lancet Neurology
17. Plaque-associated local toxicity increases over the clinical course of Alzheimer disease
    Serrano-Pozo, Alberto, Betensky, Rebecca A., Frosch, Matthew P., Hyman, Bradley T. · 2016 · The American Journal of Pathology
18. Amyloid PET in clinical practice: Its place in the multidimensional space of Alzheimer's disease
    Vandenberghe, Rik, Adamczuk, Katarzyna, Dupont, Patrick, Laere, Koen Van, Chételat, Gaël · 2013 · NeuroImage: Clinical
19. Spreading of amyloid, tau, and microvascular pathology in Alzheimer’s disease: Findings from neuropathological and neuroimaging studies.
    Thal, Dietmar Rudolf, Attems, Johannes, Ewers, Michael · 2014 · Journal of Alzheimer s Disease
20. Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator
    Snehajyoti Chatterjee, Raphaelle Cassel, Anne Schneider‐Anthony, Karine Mérienne, Brigitte Cosquer, Laura Tzeplaeff, Sarmistha Halder Sinha, Manoj Kumar, Piyush Chaturbedy, Muthusamy Eswaramoorthy et al. · 2018 · EMBO Molecular Medicine
21. Entorhinal cortex tau, amyloid-β, cortical thickness and memory performance in non-demented subjects
    David S. Knopman, Emily S. Lundt, Terry M. Therneau, Prashanthi Vemuri, Val J. Lowe, Kejal Kantarci, Jeffrey L. Gunter, Matthew L. Senjem, Michelle M. Mielke, Mary M. Machulda et al. · 2019 · Brain
22. Mitochondrial biogenesis as a therapeutic target for traumatic and neurodegenerative CNS diseases
    Epiphani C. Simmons, Natalie E. Scholpa, Rick G. Schnellmann · 2020 · Experimental Neurology
23. Frontal white matter lesions in Alzheimer’s disease are associated with both small vessel disease and AD-associated cortical pathology
    Kirsty E. McAleese, Mohi Miah, Sophie Graham, Georgina M. Hadfield, Lauren Walker, Mary Ann Johnson, Sean J. Colloby, Alan J. Thomas, Charles S DeCarli, David J. Koss et al. · 2021 · Acta Neuropathologica
24. Post-mortem histopathology underlying β-amyloid PET imaging following flutemetamol F 18 injection
    Miloš D. Ikonomović, Christopher J. Buckley, Kerstin Heurling, Paul F. Sherwin, Paul A. Jones, Michelle Zanette, Chester A. Mathis, William Edward Klunk, Aruna Chakrabarty, James W. Ironside et al. · 2016 · Acta Neuropathologica Communications
25. [18F]AV‐1451 clustering of entorhinal and cortical uptake in Alzheimer's disease
    Jennifer Louise Whitwell, Jonathan Graff‐Radford, Nirubol Tosakulwong, Stephen D. Weigand, Mary M. Machulda, Matthew L. Senjem, Christopher G. Schwarz, Anthony J. Spychalla, David Thomas Jones, Daniel A. Drubach et al. · 2018 · Annals of Neurology
26. A nonhuman primate model of early Alzheimer's disease pathologic change: Implications for disease pathogenesis
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27. A brief history of “Alzheimer disease”
    David S. Knopman, Ronald Carl Petersen, Clifford R. Jack · 2019 · Neurology
28. Structure and Mechanism of Action of Tau Aggregation Inhibitors
    Katryna K. Cisek, Grace Cooper, Carol J. Huseby, Jeff Kuret · 2014 · Current Alzheimer Research
29. Absence of amyloid β oligomers at the postsynapse and regulated synaptic Zn2+ in cognitively intact aged individuals with Alzheimer’s disease neuropathology
    Bjorklund, Nicole L, Reese, Lindsay C, Sadagoparamanujam, V-M, Ghirardi, Valeria, Woltjer, Randall L, Taglialatela, Giulio · 2012 · Molecular Neurodegeneration
30. ABCA7 Mediates Phagocytic Clearance of Amyloid-β in the Brain
    YuHong Fu, Jen-Hsiang T. Hsiao, George Paxinos, Glenda Margaret Halliday, Woojin Scott Kim · 2016 · Journal of Alzheimer s Disease
31. Characteristics of patients misdiagnosed with Alzheimer’s disease and their medication use: an analysis of the NACC-UDS database
    Gaugler, Joseph E, Ascher-Svanum, Haya, Roth, David L, Fafowora, Tolulope, Siderowf, Andrew, Beach, Thomas G · 2013 · BMC Geriatrics
32. Characterization of tau prion seeding activity and strains from formaldehyde-fixed tissue
    Sarah K. Kaufman, Talitha L. Thomas, Kelly Del Tredici, Heiko Braak, Marc I. Diamond · 2017 · Acta Neuropathologica Communications
33. Neuroprotective effects of a biodegradable poly(lactic-co-glycolic acid)-ginsenoside Rg3 nanoformulation: a potential nanotherapy for Alzheimer’s disease?
    Ravikumar Aalinkeel, Hilliard L. Kutscher, Ajay Kumar Singh, Katherine Cwiklinski, Noor Khechen, Stanley A. Schwartz, Paras N. Prasad, Supriya D. Mahajan · 2017 · Journal of drug targeting
34. Resistance and resilience to Alzheimer’s disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort
    Caitlin S. Latimer, Bridget Teevan Burke, Nicole F. Liachko, Heather N. Currey, Mitchell D. Kilgore, Laura E. Gibbons, Jonathan C. Henriksen, Martin Darvas, Kimiko Domoto‐Reilly, Suman Jayadev et al. · 2019 · Acta Neuropathologica Communications
35. Evaluating the relationship between amyloid-β and α-synuclein phosphorylated at Ser129 in dementia with Lewy bodies and Parkinson’s disease
    Marta Swirski, James Scott Miners, Rohan de Silva, Tammaryn Lashley, Helen Ling, Janice L. Holton, Tamás Révész, Seth Love · 2014 · Alzheimer s Research & Therapy
36. Efficacy and Safety of Plasma Exchange with 5% Albumin to Modify Cerebrospinal Fluid and Plasma Amyloid-β Concentrations and Cognition Outcomes in Alzheimer’s Disease Patients: A Multicenter, Randomized, Controlled Clinical Trial
    Boada, Mercè, Anaya, Fernando, Ortiz, Pilar, Olazarán, Javier, Shua-Haim, Joshua R., Obisesan, Thomas O., Hernández, Isabel, Muñoz, Joan, Buendia, Mar, Alegret, Montserrat et al. · 2017 · Journal of Alzheimer’s Disease
37. Lesions without symptoms: understanding resilience to Alzheimer disease neuropathological changes
    Gómez-Isla, Teresa, Frosch, Matthew P. · 2022 · Nature Reviews Neurology
38. Understanding the roles of mutations in the amyloid precursor protein in Alzheimer disease
    Hunter, S, Brayne, C · 2018 · Molecular Psychiatry
39. The Potential Role of MicroRNA-124 in Cerebral Ischemia Injury
    Xiaolu Liu, Zhitao Feng, Lipeng Du, Ya-Guang Huang, Jinwen Ge, Yihui Deng, Zhigang Mei · 2019 · International Journal of Molecular Sciences
40. Limbic-predominant age-related TDP-43 encephalopathy, ADNC pathology, and cognitive decline in aging
    Alifiya Kapasi, Lei Yu, Patricia A. Boyle, Lisa Laverne Barnes, David Alan Bennett, Julie A. Schneider · 2020 · Neurology
41. Considerations in the clinical use of amyloid PET and CSF biomarkers for Alzheimer's disease
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42. A preliminary study of the whole-genome expression profile of sporadic and monogenic early-onset Alzheimer's disease
    Anna Antonell, Albert Lladó, Jordi Altirriba, Teresa Botta‐Orfila, Mircea Balasa, Manel Fernández, Isidró Ferrer, Raquel Sánchez‐Valle, José Luís Molinuevo · 2013 · Neurobiology of Aging
43. Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease
    Timothy A. Couttas, Nupur Kain, Alexandra K. Suchowerska, Lake‐Ee Quek, Nigel A. Turner, Thomas Fath, Brett Garner, Anthony Simon Don · 2016 · Neurobiology of Aging
44. Frontotemporal dementia with the V337M <i>MAPT</i> mutation: Tau-PET and pathology correlations
    Spina, Salvatore, Schonhaut, Daniel R., Boeve, Bradley F., Seeley, William W., Ossenkoppele, Rik, O'Neil, James P., Lazaris, Andreas, Rosen, Howard J., Boxer, Adam L., Perry, David C. et al. · 2017 · Neurology
45. Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer’s dementia
    Sepulveda-Falla, Diego, Sanchez, Justin S., Almeida, Maria Camila, Boassa, Daniela, Acosta-Uribe, Juliana, Vila-Castelar, Clara, Ramirez-Gomez, Liliana, Baena, Ana, Aguillon, David, Villalba-Moreno, Nelson David et al. · 2022 · Acta Neuropathologica
46. Amyloid plaque structure and cell surface interactions of β-amyloid fibrils revealed by electron tomography
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47. Accuracy of Clinical Diagnosis of Dementia with Lewy Bodies versus Neuropathology
    Ragnhild Eide Skogseth, Tibor Hortobágyi, Hogne Soennesyn, Luiza Jadwiga Chwiszczuk, Dominic H Ffytche, Arvid Rongve, Clive G. Ballard, Dag Aarsland · 2017 · Journal of Alzheimer s Disease
48. CXCR4 involvement in neurodegenerative diseases
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49. Microstructural White Matter Alterations in Mild Cognitive Impairment and Alzheimer’s Disease
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50. Higher CSF Tau Levels Are Related to Hippocampal Hyperactivity and Object Mnemonic Discrimination in Older Adults
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51. Chronic Traumatic Encephalopathy in the Brains of Military Personnel
    David S. Priemer, Diego Iacono, C. Harker Rhodes, Cara H. Olsen, Daniel P. Perl · 2022 · New England Journal of Medicine
52. Comorbidities in Neurology: Is adenosine the common link?
    Detlev Boison, Eleonora Aronica · 2015 · Neuropharmacology
53. An intronic VNTR affects splicing of ABCA7 and increases risk of Alzheimer’s disease
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54. Sex differences in the genetic predictors of Alzheimer’s pathology
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55. The intact postsynaptic protein neurogranin is reduced in brain tissue from patients with familial and sporadic Alzheimer’s disease
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56. New fluid biomarkers tracking non-amyloid-β and non-tau pathology in Alzheimer’s disease
    Sun Ah Park, Song Mi Han, Chae Eun Kim · 2020 · Experimental & Molecular Medicine
57. The Longitudinal Early‐onset Alzheimer's Disease Study (LEADS): Framework and methodology
    Liana G. Apostolova, Paul S. S Aisen, Ani Eloyan, Anne M. Fagan, Keith N. Fargo, Tatiana Foroud, Constantine A. Gatsonis, Lea T. Grinberg, Clifford R. Jack, Joel H. Kramer et al. · 2021 · Alzheimer s & Dementia
58. ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology
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59. Neuroimaging correlates with neuropathologic schemes in neurodegenerative disease
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60. Increased occurrence of protein kinase CK2 in astrocytes in Alzheimer’s disease pathology
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61. Spread of pathology in amyotrophic lateral sclerosis: assessment of phosphorylated TDP-43 along axonal pathways
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62. Frequency of Biologically Defined Alzheimer Disease in Relation to Age, Sex, <i>APOE</i> ε4, and Cognitive Impairment
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63. Amyloid and tau accumulate across distinct spatial networks and are differentially associated with brain connectivity
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64. Three-dimensional mapping of neurofibrillary tangle burden in the human medial temporal lobe
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65. Cognitive and emotional alterations in App knock-in mouse models of Aβ amyloidosis
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66. Mediators of cerebral hypoperfusion and blood‐brain barrier leakiness in Alzheimer’s disease, vascular dementia and mixed dementia
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67. Microglial morphology in Alzheimer’s disease and after Aβ immunotherapy
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68. Evidence for a neuroprotective microRNA pathway in amnestic mild cognitive impairment
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69. How early can we diagnose Alzheimer disease (and is it sufficient)?
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70. Neuronal injury biomarkers and prognosis in ADNI subjects with normal cognition
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71. The informed road map to prevention of Alzheimer Disease: a call to arms
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72. Nonlinear Association Between Cerebrospinal Fluid and Florbetapir F-18 β-Amyloid Measures Across the Spectrum of Alzheimer Disease
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73. Alzheimer's disease neuropathologic change, Lewy body disease, and vascular brain injury in clinic- and community-based samples
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74. PART and SNAP
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75. Porphyromonas gingivalis is a Strong Risk Factor for Alzheimer’s Disease
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76. Alzheimer’s disease – the journey of a healthy brain into organ failure
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77. Neuropathology of Dementia Disorders
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78. Molecular imaging in dementia: Past, present, and future
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79. Performance of [¹⁸F]flutemetamol amyloid imaging against the neuritic plaque component of CERAD and the current (2012) NIA‐AA recommendations for the neuropathologic diagnosis of Alzheimer's disease
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80. Oligomers, fact or artefact? SDS-PAGE induces dimerization of β-amyloid in human brain samples
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81. CCL11 is increased in the CNS in chronic traumatic encephalopathy but not in Alzheimer’s disease
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82. Soluble TREM2 changes during the clinical course of Alzheimer’s disease: A meta-analysis
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83. Unique α-synuclein pathology within the amygdala in Lewy body dementia: implications for disease initiation and progression
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84. The central role of tau in Alzheimer’s disease: From neurofibrillary tangle maturation to the induction of cell death
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85. Traumatic Brain Injury and Risk of Long-Term Brain Changes, Accumulation of Pathological Markers, and Developing Dementia: A Review
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86. Dementia with Lewy bodies — from scientific knowledge to clinical insights
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87. Neuropathological correlates of cortical superficial siderosis in cerebral amyloid angiopathy
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88. Amyloid-β Positron Emission Tomography Imaging Probes: A Critical Review
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89. Decreased IL-8 levels in CSF and serum of AD patients and negative correlation of MMSE and IL-1β
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90. Molecular subtypes of Alzheimer’s disease
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91. Alzheimer’s Disease Neuropathological Comorbidities are Common in the Younger-Old
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92. Mild behavioral impairment is associated with progression to Alzheimer's disease: A clinicopathological study
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93. Advances in Alzheimer's disease research over the past two decades
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94. Recent Progress in Alzheimer’s Disease Research, Part 1: Pathology
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95. Integrating Gene and Protein Expression Reveals Perturbed Functional Networks in Alzheimer’s Disease
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96. Altered Waste Disposal System in Aging and Alzheimer’s Disease: Focus on Astrocytic Aquaporin-4
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97. Neuropathological assessment of the Alzheimer spectrum
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98. What is ‘Alzheimer's disease’? The neuropathological heterogeneity of clinically defined Alzheimer's dementia
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99. Tau isoforms are differentially expressed across the hippocampus in chronic traumatic encephalopathy and Alzheimer’s disease
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100. Natural Compounds May Open New Routes to Treatment of Amyloid Diseases
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