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Cited by 560

The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.

Perfusion Assessment in Laparoscopic Left-Sided/Anterior Resection (PILLAR II): A Multi-Institutional Study

Open access
Jafari, Mehraneh D., Wexner, Steven D., Martz, Joseph E., McLemore, Elisabeth C., Margolin, David A., Sherwinter, Danny A., Lee, Sang W., Senagore, Anthony J., Phelan, Michael J., Stamos, Michael J.·2015·Journal of the American College of Surgeons

Abstract

BACKGROUND: Our primary objective was to demonstrate the utility and feasibility of the intraoperative assessment of colon and rectal perfusion using fluorescence angiography (FA) during left-sided colectomy and anterior resection. Anastomotic leak (AL) after colorectal resection increases morbidity, mortality, and, in cancer cases, recurrence rates. Inadequate perfusion may contribute to AL. The PINPOINT Endoscopic Fluorescence Imaging System allows for intraoperative assessment of anastomotic perfusion. STUDY DESIGN: This is a prospective, multicenter, open-label, clinical trial that assessed the feasibility and utility of FA for intraoperative perfusion assessment during left-sided colectomy and anterior resection at 11 centers in the United States. RESULTS: A total of 147 patients were enrolled, of whom 139 were eligible for analysis. Diverticulitis (44%), rectal cancer (25%), and colon cancer (21%) were the most prevalent indications for surgery. The mean level of anastomosis was 10 ± 4 cm from the anal verge. Splenic-flexure mobilization was performed in 81% and high ligation of the inferior mesenteric artery in 61.9% of patients. There was a 99% success rate for FA, and FA changed surgical plans in 11 (8%) patients, with the majority of changes occurring at the time of transection of the proximal margin (7%). Overall morbidity rates were 17%. The anastomotic leak rate was 1.4% (n = 2). There were no anastomotic leaks in the 11 patients who had a change in surgical plan based on intraoperative perfusion assessment with FA. CONCLUSIONS: PINPOINT is a safe and feasible tool for intraoperative assessment of tissue perfusion during colorectal resection. There were no anastomotic leaks in patients in whom the anastomosis was revised based on inadequate perfusion with FA.

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Metadata

Authors
Jafari, M. D., Wexner, S. D., Martz, J. E., McLemore, E. C., Margolin, D. A., Sherwinter, D. A., Lee, S. W., Senagore, A. J., Phelan, M. J., & Stamos, M. J.
Venue
Journal of the American College of Surgeons
Published
2015-01
Volume
220
Issue
1
Pages
82-92e1
ISSN
1072-7515 (ISSN-L)
OpenAlex
W2103925331
Cited by
560
References
28
FWCI
11.35
Type
journal article
Language
en
Open access
hybrid

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Jafari, M. D., Wexner, S. D., Martz, J. E., McLemore, E. C., Margolin, D. A., Sherwinter, D. A., Lee, S. W., Senagore, A. J., Phelan, M. J., & Stamos, M. J. (2015). Perfusion Assessment in Laparoscopic Left-Sided/Anterior Resection (PILLAR II): A Multi-Institutional Study. Journal of the American College of Surgeons. https://doi.org/10.1016/j.jamcollsurg.2014.09.015

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.