Effects of platelet-rich plasma on in vitro hair follicle germ preparation for hair regenerative medicine

Autologous platelets as a source of proteins for healing and tissue regeneration

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WNT Signals Are Required for the Initiation of Hair Follicle Development

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Molecular Mechanisms Regulating Hair Follicle Development

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Platelet-Rich Plasma Injection for Chronic Achilles Tendinopathy

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Platelet-rich plasma preparation for regenerative medicine: optimization and quantification of cytokines and growth factors

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Control of hair growth and follicle size by VEGF-mediated angiogenesis

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Platelet‐rich plasma: intra‐articular knee injections produced favorable results on degenerative cartilage lesions

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Platelet Rich Plasma: a short overview of certain bioactive components

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Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth

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Mesenchymal–epithelial interactions during hair follicle morphogenesis and cycling

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The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial

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Effects of platelet‐rich plasma on bone healing in combination with autogenous bone and bone substitutes in critical‐size defects

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The Effect of Autologous Activated Platelet Rich Plasma (AA-PRP) Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation

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Fully functional hair follicle regeneration through the rearrangement of stem cells and their niches

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Selective activation of the versican promoter by epithelial– mesenchymal interactions during hair follicle development

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Enhanced Effect of Platelet-Rich Plasma Containing a New Carrier on Hair Growth

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Hair cycle-specific expression of versican in human hair follicles

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Hair follicle regeneration using grafted rodent and human cells

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Therapeutic strategy for hair regeneration: hair cycle activation, niche environment modulation, wound-induced follicle neogenesis, and stem cell engineering

Chueh, S., Lin, S., Chen, C., Lei, M., Wang, L. M., Widelitz, R. B., Hughes, M. W., Jiang, T., & Chuong, C. (2013) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2013.739601 · Cited by 91 · see citing works

Spontaneous hair follicle germ (HFG) formation in vitro, enabling the large-scale production of HFGs for regenerative medicine

Kageyama, T., Yoshimura, C., Myasnikova, D., Kataoka, K., Nittami, T., Maruo, S., & Fukuda, J. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2017.10.056 · Cited by 80 · see citing works

Strategies to enhance epithelial–mesenchymal interactions for human hair follicle bioengineering

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Platelet-derived growth factor signaling modulates adult hair follicle dermal stem cell maintenance and self-renewal

González, R., Moffatt, G. E., Hagner, A., Sinha, S., Shin, W., Rahmani, W. M., Chojnacki, A. K., & Biernaskie, J. A. (2017) · npj Regenerative Medicine · doi:10.1038/s41536-017-0013-4 · Cited by 56 · see citing works

As a carrier–transporter for hair follicle reconstitution, platelet-rich plasma promotes proliferation and induction of mouse dermal papilla cells

Xiao, S., Miao, Y., Wang, J., Jiang, W., Fan, Z., Liu, X., & Hu, Z. (2017) · Scientific Reports · doi:10.1038/s41598-017-01105-8 · Cited by 49 · see citing works

Engineering the niche for hair regeneration — A critical review

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Segmental Igfbp5 expression is specifically associated with the bent structure of zigzag hairs

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The mRNA for Protease Nexin-1 is Expressed in Human Dermal Papilla Cells and its Level is Affected by Androgen

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Evaluation of Animal Models for the Hair-Inducing Capacity of Cultured Human Dermal Papilla Cells

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Platelet-rich plasma promotes cell viability of human hair dermal papilla cells (HHDPCs) in vitro.

Wang, Y., Tang, L., Zhu, F., & Jia, M. (2017) · PubMed Central · Cited by 7 · see citing works

Reprogramming of three-dimensional microenvironments for in vitro hair follicle induction

Kageyama, T., Shimizu, A., Anakama, R., Nakajima, R., Suzuki, K., Okubo, Y., & Fukuda, J. (2022) · Science Advances · doi:10.1126/sciadv.add4603 · Cited by 73 · see citing works

Effects of the PI3K/Akt signaling pathway on the hair inductivity of human dermal papilla cells in hair beads

Yamane, M., Seo, J., Zhou, Y., Asaba, T., Tu, S., Nanmo, A., Kageyama, T., & Fukuda, J. (2022) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2022.03.010 · Cited by 46 · see citing works

Bioprinting of Hair Follicle Germs for Hair Regenerative Medicine

Nanmo, A., Yan, L., Asaba, T., Wan, L., Kageyama, T., & Fukuda, J. (2022) · Acta Biomaterialia · doi:10.1016/j.actbio.2022.06.021 · Cited by 37 · see citing works

Design of In Vitro Hair Follicles for Different Applications in the Treatment of Alopecia—A Review

Žnidarič, M., Žurga, Ž. M., & Maver, U. (2021) · Biomedicines · doi:10.3390/biomedicines9040435 · Cited by 27 · see citing works

Regenerative Cosmetics: Skin Tissue Engineering for Anti-Aging, Repair, and Hair Restoration

Pleguezuelos‐Beltrán, P., Herráiz-Gil, S., Martínez‐Moreno, D., Medraño-Fernández, I., León, C., & Guerrero‐Aspizua, S. (2024) · Cosmetics · doi:10.3390/cosmetics11040121 · Cited by 22 · see citing works

Cells, growth factors and biomaterials used in tissue engineering for hair follicles regeneration

Xu, K., Yu, E., Wu, M., Wei, P., & Yin, J. (2022) · Regenerative Therapy · doi:10.1016/j.reth.2022.11.003 · Cited by 22 · see citing works

Potential application of PBM use in hair follicle organoid culture for the treatment of androgenic alopecia

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Expansion Culture of Hair Follicle Stem Cells through Uniform Aggregation in Microwell Array Devices

Hirano, S., Kageyama, T., Yamanouchi, M., Yan, L., Suzuki, K., Ebisawa, K., Kasai, K., & Fukuda, J. (2023) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.2c01141 · Cited by 18 · see citing works

Impact of adipose-derived stem cells on engineering hair follicle germ-like tissue grafts for hair regenerative medicine

Nakajima, R., Tate, Y., Yan, L., Kageyama, T., & Fukuda, J. (2021) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2021.02.001 · Cited by 16 · see citing works

Impacts of manipulating cell sorting on in vitro hair follicle regeneration

Kageyama, T., Anakama, R., Togashi, H., & Fukuda, J. (2022) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2022.09.004 · Cited by 15 · see citing works

Large-Scale Preparation of Hair Follicle Germs Using a Microfluidic Device

Sugiyama, E., Nanmo, A., Nie, X., Chang, S., Hashimoto, M., Suzuki, A., Kageyama, T., & Fukuda, J. (2024) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.3c01346 · Cited by 14 · see citing works

Recent Trends in Macromolecule‐Based Approaches for Hair Loss Treatment

Kang, M. S., Park, T. E., Jo, H. J., Kang, M. S., Lee, S. B., Hong, S. W., Kim, K. S., & Han, D. (2023) · Macromolecular Bioscience · doi:10.1002/mabi.202300148 · Cited by 11 · see citing works

Development of in vitro hair pigmentation model using hair follicle organoids

Tu, S., Kageyama, T., Seo, J., Zhou, Y., & Fukuda, J. (2024) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2024.11.003 · Cited by 11 · see citing works

Innovative strategies for the discovery of new drugs against androgenetic alopecia

McElwee, K. J., & Sundberg, J. P. (2025) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2025.2473905 · Cited by 9 · see citing works

Emerging biomedical engineering strategies for hair follicle regeneration

Cao, X., Lu, M., Li, N., Cai, L., Wang, Y., & Zhao, Y. (2025) · Bioactive Materials · doi:10.1016/j.bioactmat.2025.06.051 · Cited by 11 · see citing works

Hair Follicle Organoids Using Human iPSC-Derived Ectodermal Precursor Cells for Hair Regenerative Medicine

Kageyama, T., Anakama, R., Hamano, S., Tu, S., Migita, Y., Asaba, T., Nanmo, A., Ishikawa, K., Yan, L., Seo, J., et al. (2026) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.5c01780 · Cited by 6 · see citing works

In Vitro and Ex Vivo Hair Follicle Models to Explore Therapeutic Options for Hair Regeneration

Bertolini, M., Piccini, I., & McElwee, K. J. (2022) · Stem cell biology and regenerative medicine · doi:10.1007/978-3-030-98331-4_8 · Cited by 5 · see citing works

The promising prospect of human hair follicle regeneration in the shadow of new tissue engineering strategies

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Cryopreservation of engineered hair follicle germs for hair regenerative medicine

Aoki, M., Yokota, R., Maruo, S., Kageyama, T., & Fukuda, J. (2023) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2023.06.006 · Cited by 2 · see citing works

Global Research Trends for Platelet-Rich Plasma: A Science Mapping with Machine Learning Techniques

Küme, T., Damar, M., ÇETİNKAYA, M. A. A. Ü., Takyaci, M., & Aydın, M. A. (2025) · Journal of AI · doi:10.61969/jai.1819178

Injectable platelet rich fibrin facilitates hair follicle regeneration by promoting human dermal papilla cell proliferation, migration, and trichogenic inductivity

Lu, K., Han, Q., Ma, Z., Yan, Q., Pei, Y., Shi, P., Zhang, J., Rong, K., Ma, K., Li, P., et al. (2021) · Experimental Cell Research · doi:10.1016/j.yexcr.2021.112888 · Cited by 29 · see citing works

As a carrier–transporter for hair follicle reconstitution, platelet-rich plasma promotes proliferation and induction of mouse dermal papilla cells

Xiao, S., Miao, Y., Wang, J., Jiang, W., Fan, Z., Liu, X., & Hu, Z. (2017) · Scientific Reports · doi:10.1038/s41598-017-01105-8 · Cited by 49 · see citing works

Spontaneous hair follicle germ (HFG) formation in vitro, enabling the large-scale production of HFGs for regenerative medicine

Kageyama, T., Yoshimura, C., Myasnikova, D., Kataoka, K., Nittami, T., Maruo, S., & Fukuda, J. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2017.10.056 · Cited by 80 · see citing works

Platelet sonicates activate hair follicle stem cells and mediate enhanced hair follicle regeneration

Zhu, M., Kong, D., Tian, R., Pang, M., Mo, M., Chen, Y., Yang, G., Cheng, H., Lei, X., Fang, K., et al. (2019) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.14873 · Cited by 40 · see citing works

Hair follicle germs containing vascular endothelial cells for hair regenerative medicine

Kageyama, T., Chun, Y., & Fukuda, J. (2021) · Scientific Reports · doi:10.1038/s41598-020-79722-z · Cited by 50 · see citing works