Frailty: An Emerging Research and Clinical Paradigm--Issues and Controversies

Frailty in Older Adults: Evidence for a Phenotype

Fried, L. P., Tangen, C. M., Walston, J., Newman, A. B., Hirsch, C., Gottdiener, J., Seeman, T., Tracy, R., Kop, W. J., Burke, G., et al. (2001) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/56.3.m146 · Cited by 24,907 · see citing works

Untangling the concepts of disability, frailty, and comorbidity: Implications for improved targeting and care

Fried, L. P., Ferrucci, L., Darer, J., Williamson, J. D., & Anderson, G. (2004) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/59.3.m255 · Cited by 4,032 · see citing works

A life course approach to chronic disease epidemiology: conceptual models, empirical challenges and interdisciplinary perspectives

Ben-Shlomo, Y. (2002) · International Journal of Epidemiology · doi:10.1093/ije/31.2.285 · Cited by 3,038 · see citing works

Living with the Past: Evolution, Development, and Patterns of Disease

Gluckman, P. D., & Hanson, M. A. (2004) · Science · doi:10.1126/science.1095292 · Cited by 1,921 · see citing works

Impact of the Metabolic Syndrome on Mortality From Coronary Heart Disease, Cardiovascular Disease, and All Causes in United States Adults

Malik, S., Wong, N. D., Franklin, S. S., Kamath, T. V., L'Italien, G. J., Pio, J. R., & Williams, G. R. (2004) · Circulation · doi:10.1161/01.cir.0000140677.20606.0e · Cited by 1,845 · see citing works

Research Agenda for Frailty in Older Adults: Toward a Better Understanding of Physiology and Etiology: Summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults

Walston, J., Hadley, E. C., Ferrucci, L., Guralnik, J. M., Newman, A. B., Studenski, S. A., Ershler, W. B., Harris, T., & Fried, L. P. (2006) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2006.00745.x · Cited by 1,605 · see citing works

Loss of 'Complexity' and Aging

Lipsitz, L. A. (1992) · JAMA · doi:10.1001/jama.1992.03480130122036 · Cited by 1,268 · see citing works

Phenotype of frailty: characterization in the women's health and aging studies

Bandeen-Roche, K., Xue, Q.-L., Ferrucci, L., Walston, J., Guralnik, J. M., Chaves, P., Zeger, S. L., & Fried, L. P. (2006) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/61.3.262 · Cited by 1,215 · see citing works

Principles of Geriatric Medicine and Gerontology.

(1991) · Annals of Internal Medicine · doi:10.7326/0003-4819-114-9-817_6 · Cited by 1,056 · see citing works

Frailty: Emergence and Consequences in Women Aged 65 and Older in the Women's Health Initiative Observational Study

Fugate Woods, N., LaCroix, A. Z., Gray, S. L., Aragaki, A., Cochrane, B. B., Brunner, R. L., Masaki, K., Murray, A., & Newman, A. B. (2005) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2005.53405.x · Cited by 1,040 · see citing works

Designing Randomized, Controlled Trials Aimed at Preventing or Delaying Functional Decline and Disability in Frail, Older Persons: A Consensus Report

Ferrucci, L., Guralnik, J. M., Studenski, S., Fried, L. P., Cutler, G. B., Walston, J. D., & The Interventions on Frailty Working Group (2004) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2004.52174.x · Cited by 1,027 · see citing works

Fetal programming and adult health

Godfrey, K. M., & Barker, D. J. P. (2001) · Public Health Nutrition · doi:10.1079/phn2001145 · Cited by 987 · see citing works

Frailty and Activation of the Inflammation and Coagulation Systems With and Without Clinical Comorbidities<subtitle>Results From the Cardiovascular Health Study</subtitle>

Walston, J. (2002) · Archives of Internal Medicine · doi:10.1001/archinte.162.20.2333 · Cited by 940 · see citing works

A program to prevent functional decline in physically frail, elderly persons who live at home

Gill, T. M., Baker, D. I., Gottschalk, M., Peduzzi, P. N., Allore, H., & Byers, A. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa020423 · Cited by 871 · see citing works

Improving memory in old age through implicit self-stereotyping.

Levy, B. R. (1996) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.71.6.1092 · Cited by 841 · see citing works

Depressive Symptoms and Physical Decline in Community-Dwelling Older Persons

Penninx, B. W. J. H. (1998) · JAMA · doi:10.1001/jama.279.21.1720 · Cited by 809 · see citing works

Associations of Subclinical Cardiovascular Disease With Frailty

Newman, A. B., Gottdiener, J. S., McBurnie, M. A., Hirsch, C. H., Kop, W. J., Tracy, R. P., Walston, J. D., & Fried, L. P. (2001) · The Journals of Gerontology Series A · doi:10.1093/gerona/56.3.m158 · Cited by 803 · see citing works

Frailty, fitness and late-life mortality in relation to chronological and biological age

Mitnitski, A. B., Graham, J., Mogilner, A. J., & Rockwood, K. J. (2002) · BMC Geriatrics · doi:10.1186/1471-2318-2-1 · Cited by 711 · see citing works

Preventing Frail Health

Büchner, D. M., & Wagner, E. H. (1992) · Clinics in Geriatric Medicine · doi:10.1016/s0749-0690(18)30494-4 · Cited by 667 · see citing works

Cytokines and cognition–the case for a head-to-toe inflammatory paradigm.

Wilson, C. J., Finch, C. E., & Cohen, H. J. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50619.x · Cited by 637 · see citing works

Improving memory in old age through implicit self-stereotyping.

Levy, B. R. (1996) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.71.6.1092 · Cited by 618 · see citing works

Old or frail: what tells us more?

Schuurmans, H., Steverink, N., Lindenberg, S., Frieswijk, N., & Slaets, J. P. J. (2004) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/59.9.m962 · Cited by 491 · see citing works

Long‐Term Risks of Death and Institutionalization of Elderly People in Relation to Deficit Accumulation at Age 70

Rockwood, K., Mitnitski, A., Song, X., Steen, B., & Skoog, I. (2006) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2006.00738.x · Cited by 481 · see citing works

Antecedents of Frailty Over Three Decades in an Older Cohort

Strawbridge, W. J., Shema, S. J., Balfour, J. L., Higby, H. R., & Kaplan, G. A. (1998) · The Journals of Gerontology Series B · doi:10.1093/geronb/53b.1.s9 · Cited by 454 · see citing works

The Association Between Obesity and the Frailty Syndrome in Older Women: The Women's Health and Aging Studies

Blaum, C. S., Xue, Q., Michelon, E., Semba, R. D., & Fried, L. P. (2005) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2005.53300.x · Cited by 433 · see citing works

The metabolic syndrome: requiescat in pace

Reaven, G. M. (2005) · Clinical Chemistry · doi:10.1373/clinchem.2005.048611 · Cited by 427 · see citing works

Models, Definitions, and Criteria of Frailty

Hogan, D. B. (2006) · Elsevier eBooks · doi:10.1016/b978-012369391-4/50051-5 · Cited by 410 · see citing works

Serum interleukin-6 and hemoglobin as physiological correlates in the geriatric syndrome of frailty: a pilot study

Leng, S., Chaves, P., Koenig, K., & Walston, J. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50315.x · Cited by 387 · see citing works

What would make a definition of frailty successful?

Rockwood, K. J. (2005) · Age and Ageing · doi:10.1093/ageing/afi146 · Cited by 382 · see citing works

The presence of frailty in elderly persons with chronic renal insufficiency

Shlipak, M. G., Stehman‐Breen, C. O., Fried, L. F., Song, X., Siscovick, D. S., Fried, L. P., Psaty, B. M., & Newman, A. B. (2004) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2003.12.049 · Cited by 364 · see citing works

Independent predictors of cognitive decline in healthy elderly persons

Marquis, S., Moore, M. M., Howieson, D. B., Sexton, G., Payami, H., Kaye, J. A., & Camicioli, R. (2002) · Archives of Neurology · doi:10.1001/archneur.59.4.601 · Cited by 344 · see citing works

Cytokines: abnormalities in major depression and implications for pharmacological treatment

O’Brien, S. M., Scott, L. V., & Dinan, T. G. (2004) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.609 · Cited by 321 · see citing works

Endocrine and inflammatory markers as predictors of frailty

Puts, M. T. E., Visser, M., Twisk, J. W. R., Deeg, D. J. H., & Lips, P. (2005) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2005.02355.x · Cited by 316 · see citing works

Motor slowing precedes cognitive impairment in the oldest old

Camicioli, R. M., Howieson, D. B., Oken, B., Sexton, G. J., & Kaye, J. A. (1998) · Neurology · doi:10.1212/wnl.50.5.1496 · Cited by 282 · see citing works

Serum levels of insulin-like growth factor-I (IGF-I) and dehydroepiandrosterone sulfate (DHEA-S), and their relationships with serum interleukin-6, in the geriatric syndrome of frailty

Leng, S. X., Cappola, A. R., Andersen, R. E., Blackman, M. R., Koenig, K., Blair, M., & Walston, J. D. (2004) · Aging Clinical and Experimental Research · doi:10.1007/bf03324545 · Cited by 270 · see citing works

The Estimation of Relative Fitness and Frailty in Community-Dwelling Older Adults Using Self-Report Data

Mitnitski, A. B., Song, X., & Rockwood, K. J. (2004) · The Journals of Gerontology Series A · doi:10.1093/gerona/59.6.m627 · Cited by 268 · see citing works

The mortality rate as a function of accumulated deficits in a frailty index

Mitnitski, A. B., Mogilner, A. J., MacKnight, C., & Rockwood, K. J. (2002) · Mechanisms of Ageing and Development · doi:10.1016/s0047-6374(02)00082-9 · Cited by 264 · see citing works

Clinical Global Impression of Change in Physical Frailty: Development of a Measure Based on Clinical Judgment

Studenski, S., Hayes, R. P., Leibowitz, R. Q., Bode, R., Lavery, L., Walston, J., Duncan, P., & Perera, S. (2004) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2004.52423.x · Cited by 252 · see citing works

The Power of Ageism on Physical Function of Older Persons: Reversibility of Age‐Related Gait Changes

Hausdorff, J. M., Levy, B. R., & Wei, J. Y. (1999) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1999.tb07437.x · Cited by 249 · see citing works

To be or Not to be: The Effects of Aging Stereotypes on the Will to Live

Levy, B. R., Ashman, O., & Dror, I. E. (2000) · OMEGA - Journal of Death and Dying · doi:10.2190/y2ge-bvyq-nf0e-83vr · Cited by 242 · see citing works

Does Sarcopenia Originate in Early Life? Findings From the Hertfordshire Cohort Study

Sayer, A. A., Syddall, H. E., Gilbody, H., Dennison, E. M., & Cooper, C. C. (2004) · The Journals of Gerontology Series A · doi:10.1093/gerona/59.9.m930 · Cited by 214 · see citing works

Functional Status of Centenarians in Tokyo, Japan: Developing Better Phenotypes of Exceptional Longevity

Gondo, Y., Hirose, N., Arai, Y., Inagaki, H., Masui, Y., Yamamura, K., Shimizu, K.-I., Takayama, M., Ebihara, Y., Nakazawa, S., et al. (2006) · The Journals of Gerontology Series A · doi:10.1093/gerona/61.3.305 · Cited by 206 · see citing works

The Course of Functional Decline in Older People with Persistently Elevated Depressive Symptoms: Longitudinal Findings from the Cardiovascular Health Study

Lenze, E. J., Schulz, R., Martire, L. M., Zdaniuk, B., Glass, T. A., Kop, W. J., Jackson, S., & Reynolds, C. F. (2005) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2005.53202.x · Cited by 204 · see citing works

The frailty syndrome: a critical issue in geriatric oncology

Ferrucci, L., Guralnik, J. M., Cavazzini, C., Bandinelli, S., Lauretani, F., Bartali, B., Repetto, L., & Longo, D. L. (2003) · Critical Reviews in Oncology/Hematology · doi:10.1016/s1040-8428(02)00177-4 · Cited by 182 · see citing works

Birth Weight, Childhood Size, and Muscle Strength in Adult Life: Evidence from a Birth Cohort Study

Kuh, D. J. (2002) · American Journal of Epidemiology · doi:10.1093/aje/kwf099 · Cited by 180 · see citing works

The Accumulation of Deficits with Age and Possible Invariants of Aging

Mitnitski, A. B., Mogilner, A. J., MacKnight, C., & Rockwood, K. J. (2002) · The Scientific World JOURNAL · doi:10.1100/tsw.2002.861 · Cited by 175 · see citing works

Frailty in Older Mexican Americans

Ottenbacher, K. J., Ostir, G. V., Peek, M. K., Snih, S. A., Raji, M. A., & Markides, K. S. (2005) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2005.53511.x · Cited by 174 · see citing works

Static and dynamic measures of frailty predicted decline in performance-based and self-reported physical functioning

Puts, M. T. E., Lips, P. T. A. M., & Deeg, D. J. H. (2005) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2005.03.008 · Cited by 172 · see citing works

MANAGEMENT OF POLYCYTHÆMIA VERA

NORMAN-WILLIAMS, C. M. (1965) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1965.tb19294.x · Cited by 171 · see citing works

The social construction of frailty: An anthropological perspective

Kaufman, S. R. (1994) · Journal of Aging Studies · doi:10.1016/0890-4065(94)90018-3 · Cited by 166 · see citing works

Childhood Socioeconomic Status Predicts Physical Functioning a Half Century Later

Guralnik, J. M., Butterworth, S., Wadsworth, M. E. J., & Kuh, D. J. (2006) · The Journals of Gerontology Series A · doi:10.1093/gerona/61.7.694 · Cited by 155 · see citing works

Developmental Origins of Midlife Grip Strength: Findings From a Birth Cohort Study

Kuh, D. J., Hardy, R., Butterworth, S., Okell, L., Wadsworth, M. E. J., Cooper, C. C., & Sayer, A. A. (2006) · The Journals of Gerontology Series A · doi:10.1093/gerona/61.7.702 · Cited by 146 · see citing works

What Is A Geriatric Syndrome Anyway?

Flacker, J. M. (2003) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2003.51174.x · Cited by 144 · see citing works

The Physics of Frailty

Bortz, W. M. (1993) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1993.tb06769.x · Cited by 133 · see citing works

Developmental Origins of Midlife Physical Performance: Evidence from a British Birth Cohort

Kuh, D. J., Hardy, R., Butterworth, S., Okell, L., Richards, M., Wadsworth, M. E. J., Cooper, C. C., & Sayer, A. A. (2006) · American Journal of Epidemiology · doi:10.1093/aje/kwj193 · Cited by 127 · see citing works

Age-related mitochondrial DNA deletion in human heart: Its relationship with cardiovascular diseases

Arai, T., Nakahara, K., Matsuoka, H., Sawabe, M., Chida, K., Matsushita, S., Takubo, K., Honma, N., Nakamura, K., Izumiyama, N., et al. (2003) · Aging Clinical and Experimental Research · doi:10.1007/bf03324472 · Cited by 99 · see citing works

AKEntAnnos. The Sardinia Study of Extreme Longevity

Deiana, L., Ferrucci, L., Pes, G. M., Carru, C., Delitala, G., Ganau, A., Mariotti, S., Nieddu, A., Pettinato, S., Putzu, P. F., et al. (1999) · Aging Clinical and Experimental Research · doi:10.1007/bf03399655 · Cited by 97 · see citing works

Développement d'un cadre de travail pour comprendre et étudier la fragilité

Bergman, H., Béland, F., Karunananthan, S., Hummel, S., Hogan, D. B., & Wolfson, C. M. (2004) · Gérontologie et société · doi:10.3917/gs.109.0015 · Cited by 95 · see citing works

Ill or just old? Towards a conceptual framework of the relation between ageing and disease

Izaks, G. J., & Westendorp, R. G. (2003) · BMC Geriatrics · doi:10.1186/1471-2318-3-7 · Cited by 89 · see citing works

FRAILTY CRITERIA GIVE HETEROGENEOUS RESULTS WHEN APPLIED IN CLINICAL PRACTICE

van Iersel, M. B., & Rikkert, M. G. M. O. (2006) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2006.00668_14.x · Cited by 81 · see citing works

Point: The Metabolic Syndrome Still Lives

Grundy, S. M. (2005) · Clinical Chemistry · doi:10.1373/clinchem.2005.050989 · Cited by 72 · see citing works

Serum C-Reactive Protein and Cognitive Function in Healthy Elderly Italian Community Dwellers

Ravaglia, G., Forti, P., Maioli, F., Brunetti, N., Martelli, M., Servadei, L., Bastagli, L., Bianchin, M., & Mariani, E. (2005) · The Journals of Gerontology Series A · doi:10.1093/gerona/60.8.1017 · Cited by 59 · see citing works

Disease, Disability, and Age in Cognitively Intact Seniors: Results From the Canadian Study of Health and Aging

Hogan, D. B., Ebly, E. M., & Fung, T. S. (1999) · The Journals of Gerontology Series A · doi:10.1093/gerona/54.2.m77 · Cited by 57 · see citing works

THE CONCEPT OF PRE-DEATH

Isaacs, B., Mckechan, A., Gunn, J., et al. (1971) · The Lancet · doi:10.1016/s0140-6736(71)91851-4 · Cited by 49 · see citing works

Frailty and the Foolishness of Eos

Ferrucci, L., Mahallati, A., & Simonsick, E. M. (2006) · The Journals of Gerontology Series A · doi:10.1093/gerona/61.3.260 · Cited by 26 · see citing works

Frailty in the medical literature

Swinne, C. J., Cornette, P., Schoevaerdts, D., et al. (1998) · Age and Ageing · doi:10.1093/ageing/27.3.411-a · Cited by 14 · see citing works

Inflammatory Proteins in Plasma and the Risk of Dementia: The Rotterdam Study

Engelhart, M. J., Geerlings, M. I., Meijer, J., Kiliaan, A., Ruitenberg, A., van Swieten, J. C., Stijnen, T., Hofman, A., Witteman, J. C. M., & Breteler, M. M. B. (2004) · Archives of Neurology · doi:10.1001/archneur.61.5.668 · Cited by 10 · see citing works

Shared Risk Factors for Falls, Incontinence, and Functional Dependence: Unifying the Approach to Geriatric Syndromes

Tinetti, M. E. (1995) · JAMA · doi:10.1001/jama.1995.03520410042024 · Cited by 6 · see citing works

Screening instruments for depression in elderly subjects

MacKnight, C., BOYDON, A., & Rockwood, K. J. (1998) · Age and Ageing · doi:10.1093/ageing/27.3.411 · Cited by 1 · see citing works

Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty

Ferrucci, L., & Fabbri, E. (2018) · Nature Reviews Cardiology · doi:10.1038/s41569-018-0064-2 · Cited by 3,690 · see citing works

A standard procedure for creating a frailty index

Searle, S. D., Mitnitski, A., Gahbauer, E. A., Gill, T. M., & Rockwood, K. (2008) · BMC Geriatrics · doi:10.1186/1471-2318-8-24 · Cited by 3,568 · see citing works

Resistance Training for Older Adults: Position Statement From the National Strength and Conditioning Association

Fragala, M. S., Cadore, E. L., Dorgo, S., Izquierdo, M., Kraemer, W. J., Peterson, M. D., & Ryan, E. D. (2019) · Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000003230 · Cited by 1,290 · see citing works

Frailty Assessment in the Cardiovascular Care of Older Adults

Afilalo, J., Alexander, K. P., Mack, M. J., Maurer, M. S., Green, P., Allen, L. A., Popma, J. J., Ferrucci, L., & Forman, D. E. (2014) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.09.070 · Cited by 1,173 · see citing works

Objectively measured physical capability levels and mortality: systematic review and meta-analysis

Cooper, R., Kuh, D., Hardy, R., Mortality Review Group, & teams, O. B. O. T. F. A. H. S. (2010) · BMJ · doi:10.1136/bmj.c4467 · Cited by 1,166 · see citing works

Prevalence and 10‐Year Outcomes of Frailty in Older Adults in Relation to Deficit Accumulation

Song, X., Mitnitski, A., & Rockwood, K. (2010) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2010.02764.x · Cited by 1,104 · see citing works

The I.A.N.A. task force on frailty assessment of older people in clinical practice

Van Kan, G. A., Rolland, Y., Bergman, H., Morley, J. E., Kritchevsky, S. B., & Vellas, B. (2008) · The Journal of nutrition, health and aging · doi:10.1007/bf02982161 · Cited by 1,099 · see citing works

The Continuum of Aging and Age-Related Diseases: Common Mechanisms but Different Rates

Franceschi, C., Garagnani, P., Morsiani, C., Conte, M., Santoro, A., Grignolio, A., Monti, D., Capri, M., & Salvioli, S. (2018) · Frontiers in Medicine · doi:10.3389/fmed.2018.00061 · Cited by 945 · see citing works

Effects of different exercise interventions on risk of falls, gait ability, and balance in physically frail older adults: a systematic review

Cadore, E. L., Rodríguez-Mañas, L., Sinclair, A., & Izquierdo, M. (2013) · Rejuvenation Research · doi:10.1089/rej.2012.1397 · Cited by 954 · see citing works

European Society for Swallowing Disorders – European Union Geriatric Medicine Society white paper: oropharyngeal dysphagia as a geriatric syndrome

Baijens, L. W., Clavé, P., Cras, P., Ekberg, O., Forster, A., Kolb, G., Leners, J. C., Masiero, S., Mateos del Nozal, J., Ortega, O., et al. (2016) · Clinical Interventions in Aging · doi:10.2147/cia.s107750 · Cited by 773 · see citing works

Gait Speed as an Incremental Predictor of Mortality and Major Morbidity in Elderly Patients Undergoing Cardiac Surgery

Afilalo, J., Eisenberg, M. J., Morin, J.-F., Bergman, H., Monette, J., Noiseux, N., Perrault, L. P., Alexander, K. P., Langlois, Y., Dendukuri, N., et al. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.06.039 · Cited by 746 · see citing works

Evidence for the Domains Supporting the Construct of Intrinsic Capacity

Cesari, M., Araujo de Carvalho, I., Amuthavalli Thiyagarajan, J., Cooper, C., Martin, F. C., Reginster, J.-Y., Vellas, B., & Beard, J. R. (2018) · The Journals of Gerontology: Series A · doi:10.1093/gerona/gly011 · Cited by 745 · see citing works

Role of Frailty in Patients With Cardiovascular Disease

Afilalo, J., Karunananthan, S., Eisenberg, M. J., Alexander, K. P., & Bergman, H. (2009) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2009.01.375 · Cited by 616 · see citing works

Cumulative deficits better characterize susceptibility to death in elderly people than phenotypic frailty: lessons from the Cardiovascular Health Study

Kulminski, A. M., Ukraintseva, S. V., Kulminskaya, I. V., Arbeev, K. G., Land, K., & Yashin, A. I. (2008) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2008.01656.x · Cited by 434 · see citing works

Prognostic significance of potential frailty criteria

Rothman, M. D., Leo‐Summers, L., & Gill, T. M. (2008) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2008.02008.x · Cited by 428 · see citing works

Frailty and the role of inflammation, immunosenescence and cellular ageing in the very old: Cross-sectional findings from the Newcastle 85+ Study

Collerton, J., Martin-Ruiz, C., Davies, K., Hilkens, C. M., Isaacs, J., Kolenda, C., Parker, C., Dunn, M., Catt, M., Jagger, C., et al. (2012) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2012.05.005 · Cited by 420 · see citing works

Inflammation and frailty measures in older people

Hubbard, R. E., O’Mahony, M. S., Savva, G. M., Calver, B. L., & Woodhouse, K. W. (2009) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2009.00733.x · Cited by 393 · see citing works

Frailty and sarcopenia - newly emerging and high impact complications of diabetes

Sinclair, A. J., Abdelhafiz, A. H., & Rodríguez-Mañas, L. (2017) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2017.05.003 · Cited by 276 · see citing works

How should we grade frailty in nursing home patients?

Rockwood, K., Abeysundera, M. J., & Mitnitski, A. (2007) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2007.07.012 · Cited by 249 · see citing works

The unmet need in the elderly: How immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines

McElhaney, J. E., Zhou, X., Talbot, H. K., Soethout, E., Bleackley, R. C., Granville, D. J., & Pawelec, G. (2012) · Vaccine · doi:10.1016/j.vaccine.2012.01.015 · Cited by 229 · see citing works

Fatigue in older adults: an early indicator of the aging process?

Avlund, K. (2010) · Aging Clinical and Experimental Research · doi:10.1007/bf03324782 · Cited by 226 · see citing works

Futility, Benefit, and Transcatheter Aortic Valve Replacement

Lindman, B. R., Alexander, K. P., O'Gara, P. T., & Afilalo, J. (2014) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2014.01.167 · Cited by 222 · see citing works

Neuroinflammation and Cognitive Aging

Ownby, R. L. (2010) · Current Psychiatry Reports · doi:10.1007/s11920-009-0082-1 · Cited by 212 · see citing works

Frailty in childhood cancer survivors

Ness, K. K., Armstrong, G. T., Kundu, M., Wilson, C. L., Tchkonia, T., & Kirkland, J. L. (2015) · Cancer · doi:10.1002/cncr.29211 · Cited by 188 · see citing works

Frailty and muscle metabolism dysregulation in the elderly

Evans, W. J., Paolisso, G., Abbatecola, A. M., Corsonello, A., Bustacchini, S., Strollo, F., & Lattanzio, F. (2010) · Biogerontology · doi:10.1007/s10522-010-9297-0 · Cited by 173 · see citing works

The psychometric properties of three self-report screening instruments for identifying frail older people in the community

Metzelthin, S. F., Daniëls, R., van Rossum, E., de Witte, L., van den Heuvel, W. J., & Kempen, G. I. (2010) · BMC Public Health · doi:10.1186/1471-2458-10-176 · Cited by 169 · see citing works

Positive effects of resistance training in frail elderly patients with dementia after long-term physical restraint

Cadore, E. L., Moneo, A. B. B., Mensat, M. M., Muñoz, A. R., Casas-Herrero, A., Rodriguez-Mañas, L., & Izquierdo, M. (2014) · AGE · doi:10.1007/s11357-013-9599-7 · Cited by 151 · see citing works

Frailty: different tools for different purposes?

Martin, F. C., & Brighton, P. (2008) · Age and Ageing · doi:10.1093/ageing/afn011 · Cited by 147 · see citing works

Screening for frailty in Canada’s health care system: A time for action

Muscedere, J., Andrew, M. K., Bagshaw, S. M., Estabrooks, C., Hogan, D., Holroyd-Leduc, J., Howlett, S., Lahey, W., Maxwell, C., McNally, M., et al. (2016) · Canadian Journal on Aging / La Revue canadienne du vieillissement · doi:10.1017/s0714980816000301 · Cited by 112 · see citing works

Functional capacity, muscle fat infiltration, power output, and cognitive impairment in institutionalized frail oldest old

Casas-Herrero, A., Cadore, E. L., Zambom-Ferraresi, F., Idoate, F., Millor, N., Martínez-Ramirez, A., Gómez, M., Rodriguez-Mañas, L., Marcellán, T., de Gordoa, A. R., et al. (2013) · Rejuvenation Research · doi:10.1089/rej.2013.1438 · Cited by 105 · see citing works

Reallocating Accelerometer-Assessed Sedentary Time to Light or Moderate- to Vigorous-Intensity Physical Activity Reduces Frailty Levels in Older Adults: An Isotemporal Substitution Approach in the TSHA Study

Mañas, A., del Pozo-Cruz, B., Guadalupe-Grau, A., Marín-Puyalto, J., Alfaro-Acha, A., Rodríguez-Mañas, L., García-García, F. J., & Ara, I. (2018) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2017.11.003 · Cited by 86 · see citing works

A correspondence analysis revealed frailty deficits aggregate and are multidimensional

Sourial, N., Wolfson, C., Bergman, H., Zhu, B., Karunananthan, S., Quail, J., Fletcher, J., Weiss, D., Bandeen-Roche, K., & Béland, F. (2010) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2009.08.007 · Cited by 85 · see citing works

Are Older Adults Who Volunteer to Participate in an Exercise Study Fitter and Healthier Than Nonvolunteers? The Participation Bias of the Study Population

Barreto, P. D. S., Ferrandez, A.-M., & Saliba-Serre, B. (2013) · Journal of Physical Activity and Health · doi:10.1123/jpah.10.3.359 · Cited by 64 · see citing works

Type 2 diabetes and impaired physical function: a growing problem

Ahmad, E., Sargeant, J. A., Yates, T., Webb, D. R., & Davies, M. J. (2022) · Diabetology · doi:10.3390/diabetology3010003 · Cited by 52 · see citing works

Depressive symptoms and frailty

St. John, P. D., Tyas, S. L., & Montgomery, P. R. (2013) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.3866 · Cited by 51 · see citing works

Development, Construct Validity, and Predictive Validity of a Continuous Frailty Scale: Results From 2 Large US Cohorts

Wu, C., Geldhof, G. J., Xue, Q.-L., Kim, D. H., Newman, A. B., & Odden, M. C. (2018) · American Journal of Epidemiology · doi:10.1093/aje/kwy041 · Cited by 45 · see citing works

High prevalence of frailty in patients with adrenal adenomas and adrenocortical hormone excess: a cross-sectional multi-centre study with prospective enrolment

Dogra, P., Šambula, L., Saini, J., Thangamuthu, K., Athimulam, S., Delivanis, D. A., Baikousi, D. A., Nathani, R., Zhang, C. D., Genere, N., et al. (2023) · European Journal of Endocrinology · doi:10.1093/ejendo/lvad113 · Cited by 38 · see citing works

The Incremental Health Care Costs of Frailty Among Home Care Recipients With and Without Dementia in Ontario, Canada: A Cohort Study

Mondor, L., Maxwell, C. J., Hogan, D. B., Bronskill, S. E., Campitelli, M. A., Seitz, D. P., & Wodchis, W. P. (2019) · Medical Care · doi:10.1097/mlr.0000000000001139 · Cited by 39 · see citing works

Older men’s definitions of frailty – the Manitoba follow-up study

St. John, P. D., McClement, S. S., Swift, A. U., & Tate, R. B. (2019) · Canadian Journal on Aging / La Revue canadienne du vieillissement · doi:10.1017/s0714980818000405 · Cited by 10 · see citing works

ИСПОЛЬЗОВAНИЕ ПОТЕНЦИAЛA СОЦИAЛЬНЫХ ПAРТНЕРОВ В ПОДГОТОВКЕ БУДУЩИХ ПЕДAГОГОВ

Атабекова, Б. Б. (2024) · Habaršy. Pedagogika ġylymdary seriâsy · doi:10.51889/2959-5762.2023.80.4.019

Susquehanna Chorale Spring Concert "Roots and Wings"

Hawkins, D. (2017)

Personality correlates and utilitarian judgments in the everyday context: Psychopathic traits and differential effects of empathy, social dominance orientation, and dehumanization beliefs

Takamatsu, R. (2019) · Personality and Individual Differences · doi:10.1016/j.paid.2019.03.029 · Cited by 22 · see citing works

Amount of altruistic punishment accounts for subsequent emotional gratification in participants with primary psychopathy

Masui, K., Iriguchi, S., Nomura, M., & Ura, M. (2011) · Personality and Individual Differences · doi:10.1016/j.paid.2011.07.006 · Cited by 14 · see citing works

The Relationship between Personality Advantage and Happiness among College Students: The Moderating Effect of Stressful Life Events

钟, 沛. (2024) · Advances in Psychology · doi:10.12677/ap.2024.148572