Preparation and application of pH-responsive drug delivery systems

New developments in liposomal drug delivery

Pattni, B. S., Chupin, V. V., & Torchilin, V. P. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00046 · Cited by 1,600

Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems

Karimi, M., Ghasemi, A., Zangabad, P. S., Rahighi, R., Basri, S. M. M., Mirshekari, H., Amiri, M., Shafaei, Z., Aslani, A., Bozorgomid, M., et al. (2016) · Chemical Society Reviews · doi:10.1039/c5cs00798d · Cited by 1,557

pH-Sensitive nano-systems for drug delivery in cancer therapy

Liu, J., Huang, Y., Kumar, A., Tan, A., Jin, S., Mozhi, A., & Liang, X.-J. (2014) · Biotechnology Advances · doi:10.1016/j.biotechadv.2013.11.009 · Cited by 1,121

Dual-Dynamic-Bond Cross-Linked Antibacterial Adhesive Hydrogel Sealants with On-Demand Removability for Post-Wound-Closure and Infected Wound Healing

Liang, Y., Li, Z., Huang, Y. P., Yu, R., & Guo, B. (2021) · ACS Nano · doi:10.1021/acsnano.1c00204 · Cited by 1,089

Tumour acidosis: from the passenger to the driver's seat

Corbet, C., & Féron, O. (2017) · Nature reviews. Cancer · doi:10.1038/nrc.2017.77 · Cited by 1,028

Mechanisms and biomaterials in pH-responsive tumour targeted drug delivery: A review

Kanamala, M., Wilson, W. R., Yang, M., Palmer, B. D., & Wu, Z. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.01.061 · Cited by 1,004

Ph sensitive hydrogels in drug delivery: brief history, properties, swelling, and release mechanism, material selection and applications

Rizwan, M., Yahya, R., Hassan, A., Yar, M., Azzahari, A., Selvanathan, V., Sonsudin, F., & Abouloula, C. (2017) · Polymers · doi:10.3390/polym9040137 · Cited by 844

Preparation and anti-triple-negative breast cancer cell effect of a nanoparticle for the codelivery of paclitaxel and gemcitabine

Yang, F., Fan, Z., Zhang, L., He, Y., Hu, R., Xiang, J., Fu, S., Wang, G., Wang, J., Tao, X., et al. (2023) · Discover Nano · doi:10.1186/s11671-023-03899-1 · Cited by 13

Endogenous stimuli-responsive drug delivery nanoplatforms for kidney disease therapy

Fang, H., Xu, S., Wang, Y., Yang, H., & Su, D. (2023) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2023.113598 · Cited by 13

Biocompatible Rhamnolipid Self‐Assemblies with pH‐Responsive Antimicrobial Activity

Kadakia, P., Valentin, J. D. P., Hong, L., Watts, S., Hameed, O. A., Walch, M., & Salentinig, S. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202302596 · Cited by 13

Self-adaptive pyroptosis-responsive nanoliposomes block pyroptosis in autoimmune inflammatory diseases

Xu, K., Huang, Y., Fang, J., Qiu, K., Shen, H., Huang, G., Zheng, Q., Wang, C., Xu, T., Yu, X., et al. (2024) · Bioactive Materials · doi:10.1016/j.bioactmat.2024.02.022 · Cited by 13

Light‐Driven Multi‐Core/Shell Microdroplets as a Targeted Drug Delivery System

Yuan, S., Yao, B., Yang, G., & Lei, H. (2024) · Advanced Functional Materials · doi:10.1002/adfm.202401905 · Cited by 13

Rational Engineering of Cytosolic Delivery Systems for Protein Therapeutics

Lv, J., Liu, X., Yin, L., & Cheng, Y. (2024) · Accounts of Materials Research · doi:10.1021/accountsmr.4c00149 · Cited by 13

Strategies to prepare polymers with cleavable linkages releasing active agents in acidic media

Kongkatigumjorn, N., & Crespy, D. (2024) · Polymer Chemistry · doi:10.1039/d4py00854e · Cited by 13

Multifunctional nanoparticles potentiate in-situ tumor vaccines via reversing insufficient Photothermal therapy by disrupting tumor vasculature

Zhao, L., Liu, Y., Jin, F., Hu, K., Lv, M., Zhou, Y., Zhao, W., Hu, Y., Wu, J., Yang, Y., et al. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.10.017 · Cited by 13

Review and Future Perspectives of Stimuli-Responsive Bridged Polysilsesquioxanes in Controlled Release Applications

Zhang, X., Zhang, H., Liu, X., Wang, J., Li, S., & Gao, P. (2024) · Polymers · doi:10.3390/polym16223163 · Cited by 13

Injectable hydrogel-assisted local lipopolysaccharide delivery improves immune checkpoint blockade therapy

Li, J., Mao, K., Meng, X., Wang, J., Zhao, M., Lv, Y., Xin, Y., Sun, H., Zhang, Y., Yang, Y.-G., et al. (2025) · Acta Biomaterialia · doi:10.1016/j.actbio.2025.01.021 · Cited by 13

Research progress on preparation, loading, and application of nanogels to protect food bioactive ingredients

Wang, D., Liu, Y., Ren, L., Jiang, Y., Meng, Y., Ma, R., Wang, S., Li, X., Cui, F., Li, J., et al. (2025) · Nano Today · doi:10.1016/j.nantod.2025.102690 · Cited by 13

The Role of Inorganic Nanomaterials in Overcoming Challenges in Colorectal Cancer Diagnosis and Therapy

Wang, J., Wang, H., Zou, F., Gu, J., Deng, S., Cao, Y., & Cai, K. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17040409 · Cited by 16

Iron–Doxorubicin Hyaluronan Nanogel as an Effective Targeted Chemotherapy with Modulated Cardiotoxicity

Guo, H. B., Wang, H., Zhang, Y., Deng, H. X., Tung, C., & Zhang, W. (2025) · Biomacromolecules · doi:10.1021/acs.biomac.4c01397 · Cited by 12

Targeting tumor acidity: pH-responsive phosphazene-COFs for synergistic co-delivery of curcumin and paclitaxel

Majeed, S., Cui, G., Zhao, D., Keshta, B. E., Khan, A. M., Wu, Z., Wang, X., & Liu, W. (2025) · Inorganic Chemistry Communications · doi:10.1016/j.inoche.2025.115215 · Cited by 12

The progress and perspective of nanomedicine in modulating the tumor immune microenvironment

Lin, N., Tan, K., Wei, Y., Xie, S., Liu, J., & Ma, X. (2025) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2025.10.002 · Cited by 13

Advances in the applications of stimulus-responsive nanomedicines for anti-cancer therapy

Tan, X., Wang, S., Zhou, X., & Yang, M. (2025) · Nanomedicine · doi:10.1080/17435889.2025.2598331 · Cited by 12

Biobased adhesive hydrogels for wound management and tissue repair: From materials to advanced applications

Miao, D., Gao, Y., Shi, B., Zhou, W., Wang, D., Zhang, J., Song, J., Cui, M., & Shi, S. (2026) · APL Bioengineering · doi:10.1063/5.0312916 · Cited by 13

Stimuli-responsive nanocarriers for precision targeted and controlled antimicrobial drug delivery in drug-resistant infections

Dai, L., & Sun, X. (2026) · Frontiers in Microbiology · doi:10.3389/fmicb.2026.1803769 · Cited by 15

Nanomedicines Based on Responsive Nanocarriers for Cancer Therapy

Liu, Z., Wen, J., Huang, C., Zhang, P., Miao, Y., Cheng, H. B., & Li, S. (2023) · Advanced Therapeutics · doi:10.1002/adtp.202300223 · Cited by 12

“Click” amphotericin B in prodrug nanoformulations for enhanced systemic fungemia treatment

Guo, D., Shi, C., Suo, L., Ji, X., Yue, H., Yuan, D., & Luo, J. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.05.003 · Cited by 13

Smart hydrogels in Lab-on-a-Chip (LOC) applications

Tevlek, A., & Cetin, E. A. (2024) · Reactive and Functional Polymers · doi:10.1016/j.reactfunctpolym.2024.106023 · Cited by 12

Self‐Assembly of Amorphous 2D Polymer Nanodiscs with Tuneable Size, pH‐Responsive Degradation and Controlled Drug Release

Zeng, H., Zeng, P., Baek, J., Kim, B., & Müllner, M. (2025) · Angewandte Chemie International Edition · doi:10.1002/anie.202424269 · Cited by 12

Dual-drug loaded hyaluronic acid conjugates coated polydopamine nanodrugs for synergistic chemo-photothermal therapy in triple negative breast cancer

Li, M., Chu, K., Zhou, Q., Wang, H., Zhang, W., Zhang, Y., Lv, J., Zhou, H., An, J., Wu, Z., et al. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.142559 · Cited by 12

Next-Generation Transformable Nanomedicines: Revolutionizing Cancer Drug Delivery and Theranostics

Shinde, S. D., Shah, S., Famta, P., Wagh, S. S., Pandey, G., Sharma, A., Vambhurkar, G. B., Jain, A., & Srivastava, S. (2025) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.4c01495 · Cited by 13

Mesoporous Potassium-Based Metal–Organic Framework as a Drug Carrier

Fang, B., Shan, T., Chen, S. Z., Pan, F., Yang, X., Xiao, D. Q., Huang, F., & Mao, Z. (2025) · ACS Central Science · doi:10.1021/acscentsci.5c00904 · Cited by 11

Enhancing lipid nanoparticles-mediated RNA delivery to glioblastoma via targeted strategies

Wang, N., Qing, Q., Xue, Y., Cai, S., Zheng, M., Zhang, D., & Ismail, M. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.114472 · Cited by 14

Recent Advances in Smart Stimulus-Responsive Hydrogels for Precision Drug Delivery in Tumours

Zuo, H., Jiao, Y., Chen, J., Tong, S., Li, Y., & Zhao, W. (2026) · Gels · doi:10.3390/gels12020098 · Cited by 11

pH/GSH dual-responsive supramolecular nanomedicine for hypoxia-activated combination therapy

Du, C., Wang, C., Jiang, S., Zheng, X., Li, Z., Yao, Y. S., Ding, Y., Chen, T., & Huan, Y. (2023) · Biomaterials Science · doi:10.1039/d3bm00519d · Cited by 11

One-Pot Synthesis of Affordable Redox-Responsive Drug Delivery System Based on Trithiocyanuric Acid Nanoparticles

Kopoleva, E., Lebedev, M. D., Postovalova, A. S., Rogova, A. S., Fatkhutdinova, L. I., Epifanovskaya, O., Goncharenko, A. A., Kremleva, A. V., Domracheva, N., Bukatin, A., et al. (2023) · Nano Letters · doi:10.1021/acs.nanolett.3c02933 · Cited by 11

Folic acid-targeted redox responsive polylactic acid-based nanoparticles co-delivering pirarubicin and salinomycin suppress breast cancer tumor growth in vivo

Gupta, P., Bansal, A., Kaur, H., Anees, M., Singh, N., & Singh, H. (2024) · Nanoscale · doi:10.1039/d4nr02365j · Cited by 11

Precise Regulations at the Subcellular Level through Intracellular Polymerization, Assembly, and Transformation

He, L., Meng, F., Chen, R., Qin, J., Sun, M., Fan, Z., & Du, J. (2024) · JACS Au · doi:10.1021/jacsau.4c00849 · Cited by 11

Advanced Bioresponsive Drug Delivery Systems for Promoting Diabetic Vascularized Bone Regeneration

Zhou, X., Chen, S., Pich, A., & He, C. (2024) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.4c02037 · Cited by 11

Advances on Albumin‐Based Carriers for Anticancer Drug Delivery

Zhou, R., Zhong, R., Luo, Z., Wei, H., & Yu, C. (2025) · Advanced NanoBiomed Research · doi:10.1002/anbr.202500011 · Cited by 11

Eco-friendly biopolymers and their biomedical applications: A review

Thakare, N. R., & Hazarika, S. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.147225 · Cited by 15

Synthesis of Hollow Calcium Carbonate Microspheres by a Template Method for DOX Loading and Release with Carbon Dots Photosensitivity

Mo, F., Chen, Q., & Zhang, X. (2022) · Materials · doi:10.3390/ma15248768 · Cited by 11

A New Paradigm for Precision Drug Delivery in Inflammatory Bowel Disease: Effective Transfer, Enhanced Retention, and Pathology‐Targeting Treatment via Biomaterials and Engineered Platforms

Gan, R., Ni, E., Li, G., & Chen, W. (2025) · MedComm – Biomaterials and Applications · doi:10.1002/mba2.70022 · Cited by 10

Stimuli-Responsive MXene Nanomaterials for Advanced Antitumor Drug Delivery Systems

Deng, P., Ling, Z., Fang, F., Ruan, J., Yang, C., Hu, R., Zhou, J., & Xiong, P. (2025) · International Journal of Nanomedicine · doi:10.2147/ijn.s552112 · Cited by 10

Fabricated soft materials for cell biology and tissue engineering applications: A review

Yang, X., Cao, H., & Li, X. (2024) · Materials Today Communications · doi:10.1016/j.mtcomm.2024.108563 · Cited by 10

ROS‐Responsive and Self‐Tumor Curing Methionine Polymer Library Based Nanoparticles with Self‐Accelerated Drug Release and Hydrophobicity/Hydrophilicity Switching Capability for Enhanced Cancer Therapy

Liu, J., You, X., Wang, L., Zeng, J., Huang, H. W., & Wu, J. (2024) · Small · doi:10.1002/smll.202401438 · Cited by 10

Boosting TNBC immune checkpoint blockade with an imaging-therapy coupled ozone delivery nano system

Song, L., Liu, Z., He, X., Xu, T., Chen, M., Xu, Z., Zhao, H., Suo, J., Wang, A., Yang, Z., et al. (2024) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.153188 · Cited by 10

Boosting disassembly of π–π stacked supramolecular nanodrugs under tumor microenvironment by introducing stimuli‐responsive drug‐mates

Xu, W., Yang, R., Xue, Y., Chen, Y., Liu, S., Zhang, S., Wang, Y., Liu, Y., & Zhang, H. (2024) · Aggregate · doi:10.1002/agt2.648 · Cited by 10

Advances in carbohydrate-based nanoparticles for targeted therapy of inflammatory bowel diseases: A review

Liang, W., Zhang, W., Tian, J., Zhang, X., Lv, X., Qu, A., Chen, J., & Wu, Z. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.136392 · Cited by 11

Bioresponsive Polymeric Nanoparticles: From Design, Targeted Therapy to Cancer Immunotherapy

Sun, H., & Zhong, Z. (2024) · Biomacromolecules · doi:10.1021/acs.biomac.4c01257 · Cited by 10

Co-delivery of doxorubicin and glycyrrhetinic acid via acid/glutathione dual responsive nano-prodrug with sodium bicarbonate carry-on for advanced combinational cancer treatment

Hu, C., Ma, J., Su, Z., Wang, J., Zhang, X., Pang, L., Qu, Y., Shi, J., & Zhang, J. (2025) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2025.02.045 · Cited by 10

Microneedles for non-transdermal drug delivery: design strategies and current applications

Xu, J., Liao, X., Chen, D., Jia, X., & Niu, X. (2025) · Bio-Design and Manufacturing · doi:10.1631/bdm.2300352 · Cited by 9

pH-responsive magnetic Fe3O4 modified chitosan nanoparticles loaded with β-acids to improve colorectal cancer treatment

Guo, S., Qiao, X., Ding, L., Liu, J., Xu, Y., Cao, J., Tian, W., Ma, D., Zhang, X., & Tian, B. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.102151 · Cited by 11

Bench-to-bedside translation of podophyllotoxin-based nanomedicines for cancer treatment: utopias and reality?

Wang, Z., Song, X.-Q., Sun, M., Zhang, R., & Yang, L. (2025) · Microstructures · doi:10.20517/microstructures.2025.71 · Cited by 11

Boolean logic-gated protein presentation through autonomously compiled molecular topology

Gharios, R., Ross, M. L., Li, A., Kottantharayil, S. P., Hoye, J. W., & DeForest, C. (2025) · Nature Chemical Biology · doi:10.1038/s41589-025-02037-5 · Cited by 12

An MMP-2 sensitive and reduction-responsive prodrug amphiphile for actively targeted therapy of cancer by hierarchical cleavage

Zhang, X., Dai, L., Ding, Y., Liu, Q., Li, X., Liu, M., Meng, M., Pan, J., Xi, R., & Yin, Y. (2022) · Chemical Communications · doi:10.1039/d2cc05586d · Cited by 10

Bibliometric and visualization analysis of the application of inorganic nanomaterials to autoimmune diseases

Zhang, B., Guo, Y., Yu, L., Ma, D., Wang, X., & Zhang, L. (2024) · Biomaterials Science · doi:10.1039/d3bm02015k · Cited by 10

Functionalities of pH-responsive DNA nanostructures in tumor-targeted strategies

Wen, L., & Wang, M. (2024) · Journal of Materials Chemistry B · doi:10.1039/d4tb01883d · Cited by 10

Assembled pH-Responsive Gastric Drug Delivery Systems Based on 3D-Printed Shells

Bei, H., Zhao, P., Shen, L. G., Yang, Q., & Yang, Y. (2024) · Pharmaceutics · doi:10.3390/pharmaceutics16060717 · Cited by 9

Recent composition and applications of liposomes in cancer therapy

Khan, I. N., Arshad, N., Shaheen, F., Shakoor, R., Hassan, A., & Waqar, M. A. (2024) · International Journal of Polymeric Materials · doi:10.1080/00914037.2024.2368896 · Cited by 9

Stable Porous Organic Cage Nanocapsules for pH-Responsive Anticancer Drug Delivery for Precise Tumor Therapy

Deng, Y., Du, Z., Du, S., Li, N., Wang, W., Su, K., & Yuan, D. (2024) · ACS Applied Bio Materials · doi:10.1021/acsabm.4c01123 · Cited by 9

Advances in Cytosolic Delivery of Proteins: Approaches, Challenges, and Emerging Technologies

Zhang, W., Liu, H., Zhu, B., Li, W., Han, X., Fu, J., Luo, R., Wang, H., & Wang, J. (2025) · Chemistry & Biodiversity · doi:10.1002/cbdv.202401713 · Cited by 10

Inhaled pH-Responsive polymyxin B-loaded albumin nanoparticles against pneumonia caused by carbapenem resistant Klebsiella pneumoniae

Li, Z., Lei, H., Hu, J., Zhou, T., Yuan, S., Ma, X., Zhu, Y., Liu, C., Wang, D., Wu, Y., et al. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.101590 · Cited by 9

Engineered Probiotics with Low Oxygen Targeting Porphyromonas gingivalis and Gingival Fibroblasts for the Treatment of Periodontitis

Li, S., Fan, Z., Zheng, K., Wu, Y., Zhong, G., & Xu, X. (2025) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.5c00111 · Cited by 9

Immune microenvironment modulation for treating inflammatory periodontal bone defects using a dynamic dual-responsive hydrogel

Yao, J., Zhang, C., Yu, C., Wu, L., Tan, L., Li, W., Gao, L., & Zhao, C. (2025) · Journal of Materials Chemistry B · doi:10.1039/d5tb00784d · Cited by 9

Engineering next-generation smart delivery materials for dentistry

Ghosh, S. K., Liang, C., Lee, S. J., & Qiao, W. (2025) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2025.103607 · Cited by 12

4D printed hydrogels for precision delivery of bioactive molecules in cancer

Gato-Diaz, U., Concheiro, Á., Alvarez‐Lorenzo, C., & Blanco‐Fernandez, B. (2025) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2025.2539959 · Cited by 9

Recent progress on composite hydrogels and their integrated devices for atmospheric water harvesting

Wu, X., He, J., Lao, Z., Ning, X., Zhu, J., & Zhang, L. (2025) · Composites Communications · doi:10.1016/j.coco.2025.102601 · Cited by 9

Nano-Drug Delivery System Targeting the Oxidative Stress Microenvironment: A Prospective Strategy for Intervertebral Disc Degeneration Treatment

Wang, Y., Wen, P., Zhang, B.-F., Hu, S., & Yang, Z. (2025) · International Journal of Nanomedicine · doi:10.2147/ijn.s529127 · Cited by 9

Hyaluronidase-responsive polymeric nanomaterials for targeted antimicrobial therapy: Structure–function relationships and biomaterial design strategy

Tabassum, N., Banicod, R. J. S., Javaid, A., Kim, Y. M., & Khan, F. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.148561 · Cited by 10

Hydrogel-Based intraperitoneal drug delivery platforms for peritoneal metastasis: strategies, advances, and prospects

Chen, X., Wei, Y., Chen, X., Zheng, L., Zhao, Y., You, J., Cheng, Y., & Yang, X. (2025) · Drug Delivery · doi:10.1080/10717544.2025.2576199 · Cited by 9

pH‐Triggered and Targeted Delivery of Curcumin: From Dendritic Polymers to Natural and Synthetic Nanocarriers

Chai, T., Zhang, M., Su, P., Wang, Z., Shao, S., Lu, C., & Jin, G. (2025) · Advanced Healthcare Materials · doi:10.1002/adhm.202504018 · Cited by 9

Engineering nanomedicine for STING pathway activation: Advancing cancer immunotherapy

Li, Z., Zhang, H., Gong, Q., & Luo, K. (2026) · Journal of Controlled Release · doi:10.1016/j.jconrel.2026.114957 · Cited by 9

Nano-drug delivery system targeting FAP for the combined treatment of oral leukoplakia

Li, R., Zhao, Y., Liu, T., Li, Y., Wan, C., Gao, R., Liu, C., Li, X., & Li, B. (2023) · Drug Delivery and Translational Research · doi:10.1007/s13346-023-01397-6 · Cited by 9

pH/GSH-responsive diselenide-containing micelle via backbone ketoxime cross-links for efficient drug delivery and controlled release

Zhou, C., Yin, W., Zhao, Y., Li, Y. Y., & Lang, M. (2024) · European Polymer Journal · doi:10.1016/j.eurpolymj.2024.112907 · Cited by 8

Role of sirtuins in cerebral ischemia-reperfusion injury: Mechanisms and therapeutic potential

Li, Z., & Xing, J. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.143591 · Cited by 8

Double-layer nanopesticide for duckweed management: Employing natural α-Terthienyl to disrupt the leaf epidermal to enhance the efficacy of prometryn

Hou, R., Fu, G., Ma, S., Tang, S., Guo, F., Wang, Y., Huang, S., Cheng, D., Zhang, Z., & Chen, Z. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.163805 · Cited by 8

Advances in Debondable Adhesives: A Focus on pH-Dependent Reversible Bonding Technologies

Muqaddas, M., Bibi, I., Atif, M. M., Asrar, M., Imtiaz, R., Tariq, H., Gohar, M. S., Kubra, K. T., & Aslam, N. (2025) · Journal of macromolecular science. Part C, Reviews in macromolecular chemistry and physics/Journal of macromolecular science. Reviews in macromolecular chemistry and physics · doi:10.1080/15583724.2025.2509209 · Cited by 8

pH sensitive loading and release of doxorubicin by chitosan-graphene quantum dots hybridized material

Ren, H., Xu, J., Lai, Y., Xu, R., Li, J., Shen, J., & Chen, J. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.145375 · Cited by 8

Overcoming the tumor microenvironment in pancreatic cancer via barrier-specific nanoparticle drug delivery

Yang, J., Kato, R., & Choi, J. H. (2025) · Nanoscale · doi:10.1039/d5nr01067e · Cited by 8

Responsive biomaterials for therapeutic strategies of hepatocellular carcinoma

Liao, X., Zhou, J., Feng, L., Wang, L., Wu, H., Li, J., Jia, Y., Wu, Q., & Shen, S. Y. (2025) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2025.1673134 · Cited by 8

A pH-responsive polycarbonate nanoplatform enables sequential drug release for enhanced apoptotic cascade synergy in non-small cell lung cancer therapy

Li, J., Liao, H., Tian, S., Liu, L., Xu, H., & Yan, L. (2025) · Acta Biomaterialia · doi:10.1016/j.actbio.2025.09.001 · Cited by 8

Chemical design of organelle-targeting molecular rotors for intracellular viscosity imaging

Han, J. J., Fang, Z., Yu, Q., Yang, N., Liu, J., & He, W. (2026) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2026.118675 · Cited by 8

Tumor Microenvironment‐Responsive PROTAC Prodrugs: A Pioneering Strategy for Precision Cancer Therapy

Yao, H., Zhang, Y., Liu, M., Gao, S., Yang, J., Xing, D., & Wang, C. (2026) · Advanced Functional Materials · doi:10.1002/adfm.202527321 · Cited by 8

Phenylboronic acid-installed poly(isobutene-alt-maleic anhydride) polymeric micelles for pH-dependent release of amphotericin B

Song, Z., Zhu, L., Xu, H., Wen, Y., & Feng, R. (2023) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2023.104225 · Cited by 7

Challenges and Opportunities of Nanomedicine: Novel Comprehensive Approaches for Brain Metastasis

Xiang, Y., Li, Z., Pan, D., Gong, Q., Luo, K., & Liu, Y. (2023) · Small Structures · doi:10.1002/sstr.202300148 · Cited by 8

Tailoring cell-inspired biomaterials to fuel cancer therapy

Wang, Q., Cheng, S., Han, C.-Y., Yang, S., Gao, S.-R., Yin, W., & Song, W.-Z. (2024) · Materials Today Bio · doi:10.1016/j.mtbio.2024.101381 · Cited by 9

MoSe2 and Al-Doped MoSe2 as targeted carriers for anti-tuberculosis drug delivery with controlled release: A first-principles DFT study

Arnab, S. R., Halder, J., & Islam, M. S. (2025) · Inorganic Chemistry Communications · doi:10.1016/j.inoche.2025.113979 · Cited by 8

Responsive Zwitterionic Materials for Enhanced Drug Delivery

Zheng, K., Ouyang, X., Hong, X., & Peng, S. (2025) · Langmuir · doi:10.1021/acs.langmuir.4c04809 · Cited by 8

Enzyme/pH dual stimuli-responsive nanoplatform co-deliver disulfiram and doxorubicin for effective treatment of breast cancer lung metastasis

Xiao, P., Tao, X., Wang, H., Liu, H., Feng, Y., Zhu, Y., Jiang, Z., Yin, T., Zhang, Y. X., He, H., et al. (2023) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2023.2237888 · Cited by 8

Stimuli-Responsive Nodal Dual-Drug Polymer Nanoparticles for Cancer Therapy

Kuang, G., Ding, J., Xie, W., Ye, Z., & Zhang, Q. (2025) · International Journal of Nanomedicine · doi:10.2147/ijn.s517291 · Cited by 7

Strategies of tea polyphenol-mediated delivery systems based on Mannich reaction for precision nutrition.

Song, Y.-K., Zhang, X.-M., Chen, Y.-P., Chen, Y.-N., Wang, H.-H., Su, W.-T., Cheng, S.-S., Wang, H.-T., & Tan, M.-Q. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.114135 · Cited by 7

Hydrogels from Renewable Resources: Advances in 3D Networks Based on Cellulose and Hemicellulose

Ciolacu, D. E. (2025) · Polymers · doi:10.3390/polym17202760 · Cited by 7

Advances of soft robotics for gastrointestinal tract applications

Du, M., Xie, Z., & Wang, X. (2025) · Soft Science · doi:10.20517/ss.2025.61 · Cited by 7

Structure- or size-transformable peptide-based antibacterial biomaterials: Design strategies, functions, and applications

Chen, Z., Zhao, G., Qu, Y., Tang, Q., Yang, S., Zhou, C., Li, M., Kang, Y., Tan, P., & Ma, X. (2025) · Acta Biomaterialia · doi:10.1016/j.actbio.2025.10.035 · Cited by 7

Photosensitizing Lipid Nanoparticles for Ferroptosis‐Enhanced Photodynamic Cancer Therapy via GPX4 Silencing

Bae, G., Shin, S., Park, J. D., Koh, E., Ko, S., Han, J., Park, C. G., Kim, D., Na, K., & Park, W. (2025) · Advanced Healthcare Materials · doi:10.1002/adhm.202503748 · Cited by 7

Polysaccharide hydrogel loaded with dual-drug liposomes for accelerating diabetic wound healing through mitochondrial protection and anti-inflammatory activity

Guo, Q., Tian, J., Huang, Y., Wu, H., Men, J., Xiang, T., & Li, K. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.148969 · Cited by 7

Stimuli-responsive nanomedicines for hepatic diseases: mechanism, design, recent advances, and clinical translation

Wang, L., Zhang, X., Li, Y., Zhao, M., Xu, G., Duan, Z., Gong, Q., & Luo, K. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.114522 · Cited by 9

Piezo-type mechanosensitive ion channel component 1: a mechano-bioenergetic transducer in the tumour microenvironment

Zhang, Y., Gao, C., Li, Y., Fu, Q., Liu, Y., Mo, N., Yue, J., & Wang, Y. (2025) · Annals of Medicine · doi:10.1080/07853890.2025.2603022 · Cited by 8

Design Principles of Oral Nanomedicines to Overcome the Delivery Barriers

Yang, K., Li, B., Jiang, A., Shi, X., Nie, G., & Xiao, B. (2026) · ACS Nano · doi:10.1021/acsnano.5c14045 · Cited by 8

Applications of Stimuli‐Responsive Hydrogels in Renewable Energy: A Review

Song, X., Dong, X., Liu, H., Wang, Z., & Cao, Q. (2026) · ChemSusChem · doi:10.1002/cssc.202501440 · Cited by 7

Smart natural polymer-based hydrogels for chronic wound management: advances in real-time monitoring and stimuli-responsive therapy

Liu, Y.-Q., Luo, J.-H., Xu, Z.-J., Wang, R., Yan, M., Kang, Z.-F., Wang, Z., Ren, B.-B., Xu, J., & Li, Z.-M. (2026) · Journal of Materials Chemistry B · doi:10.1039/d5tb02894a · Cited by 7

Dendrimers in cancer therapy: emerging clinical design strategies

li, J., & Kwok, H. F. (2026) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2026.04.005 · Cited by 7

Cyano-modulated Zn(II)-Schiff base complexes for lysosome-targeted fluorescence imaging and pH-responsive camptothecin delivery

Zhang, X., Sun, W., Li, X., Li, Y., Xiang, S., Zhang, L., & Yang, Y. (2026) · International Journal of Pharmaceutics X · doi:10.1016/j.ijpx.2026.100594 · Cited by 7

Revolutionizing lung cancer treatment with smart pulmonary drug delivery nanosystems

Gamal, O., Agamey, A. T., Mohamed, Z. A., & El-sherbiny, I. M. (2024) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2024.106158 · Cited by 7

The Construction of pH-Sensitive Starch-Based Carrier to Control the Delivery of Curcumin for Fish Preservation

Guo, X., Liu, S., Yang, L., Zhao, C., Liu, S., Xiong, G., Chen, L., Chen, S., Wu, W., & Wang, L. (2024) · Food and Bioprocess Technology · doi:10.1007/s11947-024-03389-x · Cited by 6

pH-Responsive Micro/Nano Drug Delivery

Nouri, B., Montazer, M., & Malek, R. M. A. (2024) · CRC Press eBooks · doi:10.1201/9781003468424-15

pH-sensitive drug delivery systems

Ghaffar, A., Yameen, B., Latif, M., & Malik, M. I. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-816960-5.00014-8 · Cited by 23

Ph-responsive drug delivery systems as intelligent carriers for targeted drug therapy: brief history, properties, synthesis, mechanism and application

Bami, M. S., Raeisi Estabragh, M. A., Khazaeli, P., Ohadi, M., & Dehghannoudeh, G. (2022) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2021.102987 · Cited by 101

Microenvironment-Activated Smart Drug Delivery System: An Integrated Review of pH-Responsive Polymers, Nanocarriers and Dual-Stimuli Innovation

Vanitha S*, B. A. (2026) · Zenodo (CERN European Organization for Nuclear Research) · doi:10.5281/zenodo.20839250

pH-Sensitive Nanomaterials for Smart Release of Drugs

Meher, M. K., & Poluri, K. M. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-817830-0.00002-3 · Cited by 10