Effects of post-ICU follow-up on subject outcomes: A systematic review and meta-analysis
Abstract
Purpose The present systematic review and meta-analysis aimed to synthesize data on subject outcomes associated with post-ICU follow-up.Materials and methods MEDLINE, PsycINFO, CINAHL, Cochrane CENTRAL, and EMBASE databases were searched according to pre-specified criteria (PROSPERO- CRD42017074734). Non-randomized and randomized studies assessing patient and family outcomes associated with post-ICU follow-up were included.Results Twenty-six studies were included. Sixteen (61%) were randomized trials; of these, 15 were meta-analyzed. Non-randomized studies reported benefits in survival, functional status, anxiety, depression, and posttraumatic stress disorder (PTSD) symptoms, and satisfaction. In randomized trials, post-ICU follow-up models focusing on physical therapy were associated with fewer depression symptoms (mean difference [MD], -1.21 (see Fig. 2); 95% confidence interval [CI], -2.31 to -0.11; I 2 = 0%) and better mental health-related quality of life scores (standardized MD [SMD], 0.26; 95%CI, 0.02 to 0.51; I 2 = 6%) in the short term. Post-ICU follow-up models focusing on psychological or medical management interventions were associated with fewer PTSD symptoms (SMD, -0.21; 95%CI, -0.37 to -0.05; I 2 = 0%) in the medium term.Conclusions Post-ICU follow-up may improve depression symptoms and mental health-related quality of life in the short term for models focusing on physical therapy and PTSD symptoms in the medium term for models focusing on psychological or medical management interventions.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Two of the follow-up reviews reported that the interventions could be helpful to improve psychological outcomes.
“Two of the studies114 115 reported that the interventions could be helpful to improve psychological outcomes.”
From Impact of healthcare interventions on distress following acute musculoskeletal/orthopaedic injury: A scoping review of systematic reviews (2024) · cites this paper as [115]
Cites
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823 · see citing works
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & The PRISMA Group (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000097 · Cited by 64,042 · see citing works
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859 · see citing works
The Cochrane Collaboration's tool for assessing risk of bias in randomised trials
Higgins, J. P. T., Altman, D. G., Gotzsche, P. C., Juni, P., Moher, D., Oxman, A. D., Savovic, J., Schulz, K. F., Weeks, L., Sterne, J. A. C., et al. (2011) · BMJ · doi:10.1136/bmj.d5928 · Cited by 33,817 · see citing works
Rayyan-a web and mobile app for systematic reviews.
Ouzzani, M., Hammady, H., Fedorowicz, Z., & Elmagarmid, A. (2016) · Systematic Reviews · doi:10.1186/s13643-016-0384-4 · Cited by 26,092 · see citing works
Process evaluation of complex interventions: Medical Research Council guidance
Moore, G. F., Audrey, S., Barker, M., Bond, L., Bonell, C., Hardeman, W., Moore, L., O'Cathain, A., Tinati, T., Wight, D., et al. (2015) · BMJ · doi:10.1136/bmj.h1258 · Cited by 6,204 · see citing works
Needham, D. M., Davidson, J., Cohen, H., Hopkins, R. O., Weinert, C., Wunsch, H., Zawistowski, C., Bemis-Dougherty, A., Berney, S. C., Bienvenu, O. J., et al. (2012) · Critical Care Medicine · doi:10.1097/ccm.0b013e318232da75 · Cited by 2,639 · see citing works
Long-term cognitive impairment and functional disability among survivors of severe sepsis.
Iwashyna, T. J., Ely, E. W., Smith, D. M., & Langa, K. M. (2010) · JAMA · doi:10.1001/jama.2010.1553 · Cited by 2,582 · see citing works
Newcastle-Ottawa Scale: comparing reviewers’ to authors’ assessments
Lo, C. K.-L., Mertz, D., & Loeb, M. (2014) · BMC Medical Research Methodology · doi:10.1186/1471-2288-14-45 · Cited by 2,477 · see citing works
Enhancing Recovery From Sepsis: A Review
Prescott, H. C., & Angus, D. C. (2018) · JAMA · doi:10.1001/jama.2017.17687 · Cited by 1,059 · see citing works
Long-term complications of critical care
Desai, S. V., Law, T. J., & Needham, D. M. (2010) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181fd66e5 · Cited by 870 · see citing works
Cuthbertson, B. H., Rattray, J., Campbell, M. K., Gager, M., Roughton, S., Smith, A., Hull, A., Breeman, S., Norrie, J., Jenkinson, D., et al. (2009) · BMJ · doi:10.1136/bmj.b3723 · Cited by 488 · see citing works
Rehabilitation after critical illness: A randomized, controlled trial.
Jones, C., Skirrow, P., Griffiths, R. D., Humphris, G. H., Ingleby, S., Eddleston, J., Waldmann, C., & Gager, M. (2003) · Critical Care Medicine · doi:10.1097/01.ccm.0000089938.56725.33 · Cited by 446 · see citing works
Myhren, H., Ekeberg, Ø., Tøien, K., Karlsson, S., & STOKLAND, O. (2010) · Critical Care · doi:10.1186/cc8870 · Cited by 344 · see citing works
Post-traumatic stress disorder-related symptoms in relatives of patients following intensive care
Jones, C., Skirrow, P. M., Griffiths, R. D., Humphris, G., Ingleby, S., EDDLESTON, J. M., Waldmann, C. S., & Gager, M. (2004) · Intensive Care Medicine · doi:10.1007/s00134-003-2149-5 · Cited by 340 · see citing works
Jackson, J. C., Ely, E. W., Morey, M. C., Anderson, V. M., Denne, L. B., Clune, J., Siebert, C. S., Archer, K. R., Torres, R., Janz, D., et al. (2012) · Critical Care Medicine · doi:10.1097/ccm.0b013e3182373115 · Cited by 318 · see citing works
Walsh, T. S., Salisbury, L. G., Merriweather, J. L., Boyd, J. A., Griffith, D. M., Huby, G., Kean, S., Mackenzie, S. J., Krishan, A., Lewis, S. C., et al. (2015) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2015.0822 · Cited by 301 · see citing works
Reported burden on informal caregivers of ICU survivors: a literature review
van Beusekom, I., Bakhshi‐Raiez, F., de Keizer, N. F., Dongelmans, D. A., & van der Schaaf, M. (2016) · Critical Care · doi:10.1186/s13054-016-1185-9 · Cited by 293 · see citing works
Five-Year Mortality and Hospital Costs Associated with Surviving Intensive Care
Lone, N., Gillies, M., Haddow, C., Dobbie, R., Rowan, K., Wild, S. H., Murray, G. D., & Walsh, T. S. (2016) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201511-2234oc · Cited by 251 · see citing works
Elliott, D., McKinley, S., Alison, J., Aitken, L. M., King, M., Leslie, G. D., Kenny, P., Taylor, P., Foley, R., & Burmeister, E. (2011) · Critical Care · doi:10.1186/cc10265 · Cited by 250 · see citing works
Knowles, R. J., & Tarrier, N. (2008) · Critical Care Medicine · doi:10.1097/ccm.0b013e31819287f7 · Cited by 216 · see citing works
Jensen, J. F., Thomsen, T., Overgaard, D., Bestle, M. H., Christensen, D., & Egerod, I. (2015) · Intensive Care Medicine · doi:10.1007/s00134-015-3689-1 · Cited by 185 · see citing works
Schmidt, K., Worrack, S., Von Korff, M., Davydow, D., Brunkhorst, F., Ehlert, U., Pausch, C., Mehlhorn, J., Schneider, N., Scherag, A., et al. (2016) · JAMA · doi:10.1001/jama.2016.7207 · Cited by 179 · see citing works
Recovery after critical illness: putting the puzzle together—a consensus of 29
Azoulay, É., Vincent, J., Angus, D. C., Arabi, Y. M., Brochard, L. J., Brett, S. J., Citerio, G., Cook, D. J., Curtis, J. R., dos Santos, C. C., et al. (2017) · Critical Care · doi:10.1186/s13054-017-1887-7 · Cited by 165 · see citing works
Jensen, J. F., Egerod, I., Bestle, M. H., Christensen, D. F., Elklit, A., Hansen, R. L., Knudsen, H., Grode, L. B., & Overgaard, D. (2016) · Intensive Care Medicine · doi:10.1007/s00134-016-4522-1 · Cited by 150 · see citing works
Chao, P.-W., Shih, C.-J., Lee, Y.-J., Tseng, C.-M., Kuo, S., Shih, Y.-N., Chou, K., Tarng, D., Li, S., Ou, S., et al. (2014) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201406-1170oc · Cited by 121 · see citing works
Critical Care Follow-up Clinics
Lasiter, S., Oles, S. K., Mundell, J., London, S. K., & Khan, B. A. (2016) · Clinical Nurse Specialist · doi:10.1097/nur.0000000000000219 · Cited by 121 · see citing works
Early and Late Unplanned Rehospitalizations for Survivors of Critical Illness*
Hua, M. S., Gong, M. N., Brady, J. E., & Wunsch, H. (2014) · Critical Care Medicine · doi:10.1097/ccm.0000000000000717 · Cited by 107 · see citing works
Jones, C., EDDLESTON, J. M., McCairn, A., Dowling, S., McWilliams, D. J., Coughlan, E., & Griffiths, R. D. (2015) · Journal of Critical Care · doi:10.1016/j.jcrc.2015.05.002 · Cited by 96 · see citing works
Batterham, A. M., Bonner, S., Wright, J., Howell, S. J., Hugill, K., & Danjoux, G. (2014) · British Journal of Anaesthesia · doi:10.1093/bja/aeu051 · Cited by 92 · see citing works
Khan, B. A., Lasiter, S., & Boustani, M. A. (2015) · AJN American Journal of Nursing · doi:10.1097/01.naj.0000461807.42226.3e · Cited by 91 · see citing works
Follow-up after intensive care: a single center study
Kvåle, R., Ulvik, A., & Flaatten, H. K. (2003) · Intensive Care Medicine · doi:10.1007/s00134-003-2034-2 · Cited by 88 · see citing works
McDowell, K., O'Neill, B., Blackwood, B., Clarke, C., Gardner, E., Johnston, P., Kelly, M., McCaffrey, J., Mullan, B., Murphy, S., et al. (2017) · Thorax · doi:10.1136/thoraxjnl-2016-208723 · Cited by 84 · see citing works
Douglas, S. L., Daly, B. J., Kelley, C. G., O’Toole, E., & Montenegro, H. (2007) · American Journal of Critical Care · doi:10.4037/ajcc2007.16.5.447 · Cited by 82 · see citing works
Connolly, B., Thompson, A., Douiri, A., Moxham, J., & Hart, N. (2015) · Journal of Critical Care · doi:10.1016/j.jcrc.2015.02.002 · Cited by 81 · see citing works
Post-intensive care outpatient clinic: Is it feasible and effective? A literature review.
Teixeira, C., & Rosa, R. G. (2018) · Revista Brasileira de Terapia Intensiva · doi:10.5935/0103-507x.20180016 · Cited by 77 · see citing works
Self-citationMcWilliams, D. J., Atkinson, D., Carter, A., Foex, B. A., Benington, S., & Conway, D. H. (2009) · Physiotherapy Theory and Practice · doi:10.3109/09593980802668076 · Cited by 75 · see citing works
McWilliams, D. J., Benington, S., & Atkinson, D. (2016) · Physiotherapy Theory and Practice · doi:10.3109/09593985.2015.1137663 · Cited by 61 · see citing works
Samuelson, K. A. M., & Corrigan, I. (2009) · Nursing in Critical Care · doi:10.1111/j.1478-5153.2009.00336.x · Cited by 54 · see citing works
Schandl, A. R., Bottai, M., Hellgren, E., Sundin, Ö., & Sackey, P. (2012) · Critical Care · doi:10.1186/cc11338 · Cited by 41 · see citing works
Rosa, R. G., Kochhann, R., Berto, P. P., Biason, L., Maccari, J. G., de Leon, P., Dutra, F. H., da Silva, S. F., Sganzerla, D., Schneider, D., et al. (2018) · Intensive Care Medicine · doi:10.1007/s00134-018-5146-4 · Cited by 34 · see citing works
Self-citationvan Beusekom, I., Bakhshi‐Raiez, F., van der Schaaf, M., Busschers, W. B., de Keizer, N. F., & Dongelmans, D. A. (2019) · Critical Care Medicine · doi:10.1097/ccm.0000000000003576 · Cited by 25 · see citing works
Jónasdóttir, R. J., Jones, C., Sigurdsson, G. H., & Jónsdóttir, H. (2017) · Journal of Advanced Nursing · doi:10.1111/jan.13485 · Cited by 22 · see citing works
Bohart, S., Egerod, I., Bestle, M. H., Overgaard, D., Christensen, D. F., & Jensen, J. F. (2018) · Intensive and Critical Care Nursing · doi:10.1016/j.iccn.2018.03.002 · Cited by 20 · see citing works
Dettling-Ihnenfeldt, D. S., de Graaff, A. E., Nollet, F., & van der Schaaf, M. (2015) · PubMed · Cited by 19 · see citing works
Choi, S., Lee, J., Shin, Y., Lee, J., Jung, J., Han, M., Son, J., Jung, Y., Lee, S., Hong, S., et al. (2016) · Journal of Evaluation in Clinical Practice · doi:10.1111/jep.12485 · Cited by 16 · see citing works
Intensive after care after intensive care
Waldmann, C. S. (1998) · Current Anaesthesia and Critical Care · doi:10.1016/s0953-7112(98)80007-0 · Cited by 13 · see citing works
Herridge, M. S. (2000) · Current Opinion in Critical Care · doi:10.1097/00075198-200006000-00005 · Cited by 2 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Sim, A., McNeilage, A. G., Gholamrezaei, A., Rebbeck, T., & Ashton-James, C. (2024) · BMJ Open · doi:10.1136/bmjopen-2024-085778 · Cited by 8 · see citing works
- Authors
- Rosa, R. G., Ferreira, G. E., Viola, T. W., Robinson, C. C., Kochhann, R., Berto, P. P., Biason, L., Cardoso, P. R., Falavigna, M., & Teixeira, C.
- Affiliations
- The University of Sydney (AU)
- Pontifícia Universidade Católica do Rio Grande do Sul (BR)
- Hospital de Clínicas de Porto Alegre (BR)
- Hospital Moinhos de Vento (BR)
- ORCID
- Venue
- Journal of Critical Care
- Publisher
- Elsevier BV
- Published
- 2019-08
- Volume
- 52
- Pages
- 115-125
- ISSN
- 0883-9441 (ISSN-L)
- OpenAlex
- W2940064345
- Cited by
- 170
- References
- 48
- Citations by year
- 2026: 25 · 2025: 32 · 2024: 36 · 2023: 29 · 2022: 16 · 2021: 19 · 2020: 8 · 2019: 4
- FWCI
- 2.70
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Critical Care (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Brazilian Ministry of Health
- Topics
- Health Sciences › Health Professions › Radiological and Ultrasound Technology › Family and Patient Care in Intensive Care Units
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Intensive Care Unit Cognitive Disorders
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Keywords
- post-ICU follow-up, intensive care unit survivors, physiotherapy, depression, post-traumatic stress disorder, mental health-related quality of life, anxiety, family outcomes, patient outcomes, long-term follow-up
- MeSH terms
- Anxiety, Clinical Trials as Topic, Critical Care, Depression, Follow-Up Studies, Humans, Intensive Care Units, Patient Discharge, Quality of Life, Risk, Stress Disorders, Post-Traumatic, Physical Therapy Modalities
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
