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Cited by 800Skin Protection and AgingAntioxidant Activity and Oxidative Stressmelanin and skin pigmentation

The DOI matches its Crossref record; 83 of the 83 references it cites were found in a registry or an index.

Role of antioxidants in the skin: Anti-aging effects

Masaki, Hitoshi·2010·Journal of Dermatological Science
DOI 10.1016/j.jdermsci.2010.03.003
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Abstract

Intracellular and extracellular oxidative stress initiated by reactive oxygen species (ROS) advance skin aging, which is characterized by wrinkles and atypical pigmentation. Because UV enhances ROS generation in cells, skin aging is usually discussed in relation to UV exposure. The use of antioxidants is an effective approach to prevent symptoms related to photo-induced aging of the skin. In this review, the mechanisms of ROS generation and ROS elimination in the body are summarized. The effects of ROS generated in the skin and the roles of ROS in altering the skin are also discussed. In addition, the effects of representative antioxidants on the skin are summarized with a focus on skin aging.

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Crossref · 10.1016/j.jdermsci.2010.03.003

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Metadata

Authors
Masaki, H.
Affiliations
Cosmos Technical Center Co., Ltd. (Japan) (JP)
Corresponding author
Masaki, Hitoshi
ORCID
Masaki, Hitoshi
Venue
Journal of Dermatological Science
Publisher
Elsevier BV
Published
2010-05
Volume
58
Issue
2
Pages
85-90
ISSN
0923-1811 (ISSN-L)
DOI
10.1016/j.jdermsci.2010.03.003
OpenAlex
W2078923345
Cited by
788
References
83
Citations by year
2026: 48 · 2025: 71 · 2024: 77 · 2023: 61 · 2022: 87 · 2021: 73 · 2020: 56 · 2019: 58 · 2018: 53 · 2017: 36 · 2016: 37 · 2015: 36 · 2014: 37 · 2013: 17 · 2012: 18
FWCI
3.25
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Journal of Dermatological Science (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Dermatology › Skin Protection and Aging
  • Health Sciences › Medicine › Biochemistry (medical) › Antioxidant Activity and Oxidative Stress
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
Keywords
antioxidants, skin aging, oxidative stress, reactive oxygen species, photoaging, ultraviolet radiation, wrinkles, hyperpigmentation, reactive oxygen species scavenging
MeSH terms
Aging, Antioxidants, Ascorbic Acid, Carotenoids, Flavonoids, Humans, Inflammation, Models, Biological, Phenols, Sebaceous Glands, Skin, Ultraviolet Rays, Vitamin E, Skin Aging, Reactive Oxygen Species, Oxidative Stress, Polyphenols

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