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Effect of extraction solvent on total phenol content, total flavonoid content, and antioxidant activity of Limnophila aromatica
Open accessAbstract
Limnophila aromatica is commonly used as a spice and a medicinal herb in Southeast Asia. In this study, water and various concentrations (50%, 75%, and 100%) of methanol, ethanol, and acetone in water were used as solvent in the extraction of L. aromatica. The antioxidant activity, total phenolic content, and total flavonoid content of the freeze-dried L. aromatica extracts were investigated using various in vitro assays. The extract obtained by 100% ethanol showed the highest total antioxidant activity, reducing power and DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging activity. The same extract also exhibited the highest phenolic content (40.5 mg gallic acid equivalent/g of defatted L. aromatica) and the highest flavonoid content (31.11 mg quercetin equivalent/g of defatted L. aromatica). The highest extraction yield was obtained by using 50% aqueous acetone. These results indicate that L. aromatica can be used in dietary applications with a potential to reduce oxidative stress.
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Research works printed but not linked: 29
- Pérez-Jiménez, 2008, Updated methodology to determine antioxidant capacity in plant foods, oils and beverages: extraction, measurement and expression of results, Food Res Int, 41, 274, 10.1016/j.foodres.2007.12.004 · DOI · Paper page
- Miliauskas, 2004, Screening of radical scavenging activity of some medicinal and aromatic plant extracts, Food Chem, 85, 231, 10.1016/j.foodchem.2003.05.007 · DOI · Paper page
- King, 1999, Characteristics and occurrence of phenolic phytochemicals, J Am Diet Assoc, 99, 213, 10.1016/S0002-8223(99)00051-6 · DOI · Paper page
- Turkmen, 2006, Effects of extraction solvents on concentration and antioxidant activity of black and black mate tea polyphenols determined by ferrous tartrate and Folin–Ciocalteu methods, Food Chem, 99, 835, 10.1016/j.foodchem.2005.08.034 · DOI · Paper page
- Dai, 2010, Plant phenolics: extraction, analysis and their antioxidant and anticancer properties, Molecules, 15, 7313, 10.3390/molecules15107313 · DOI · Paper page
- Bonoli, 2004, Antioxidant phenols in barley (Hordeum vulgare L.) flour: comparative spectrophotometric study among extraction methods of free and bound phenolic compounds, J Agric Food Chem, 52, 5195, 10.1021/jf040075c · DOI · Paper page
- Wang, 2001, Determination of flavonols in green and black tea leaves and green tea infusions by high-performance liquid chromatography, Food Res Int, 34, 223, 10.1016/S0963-9969(00)00156-3 · DOI · Paper page
- Venkata Rao, 1989, Antimicrobial activity of the essential oil of Limnophila gratissima, Fitoterapia, 60, 376
- Krishnan, 1999, Uncommon 8-oxygenated flavonoids from Limnophila aromatica (Scrophulariaceae), Indian J Chem, 38B, 1009
- Bui, 2004, Uncommon 8-oxygenated flavonoids from Limnophila aromatica (Scrophulariaceae), Biochem Syst Ecol, 32, 943, 10.1016/j.bse.2004.03.001 · doi:10.1016/j.bse.2004.03.001
- McDonald, 2001, Phenolic content and antioxidant activity of olive extracts, Food Chem, 73, 73, 10.1016/S0308-8146(00)00288-0 · DOI · Paper page
- Chang, 2002, Estimation of total flavonoid content in propolis by two complementary colorimetric methods, J Food Drug Anal, 10, 178
- Govindarajan, 2003, Studies on the antioxidant activities of Desmodium gangeticum, Biol Pharm Bull, 26, 1424, 10.1248/bpb.26.1424 · DOI · Paper page
- Subhasree, 2009, Evaluation of antioxidant potential in selected green leafy vegetables, Food Chem, 115, 1213, 10.1016/j.foodchem.2009.01.029 · DOI · Paper page
- Chu, 2000, Flavonoid content of several vegetables and their antioxidant activity, J Sci Food Agric, 80, 561, 10.1002/(SICI)1097-0010(200004)80:5<561::AID-JSFA574>3.0.CO;2-# · DOI · Paper page
- Shimada, 1992, Antioxidative properties of xanthan on the autoxidation of soybean oil in cyclodextrin emulsion, J Agric Food Chem, 40, 945, 10.1021/jf00018a005 · DOI · Paper page
- Stalikas, 2007, Extraction, separation, and detection methods for phenolic acids and flavonoids, J Sep Sci, 30, 3268, 10.1002/jssc.200700261 · DOI · Paper page
- Zieliński, 2000, Antioxidant activity and total phenolics in selected cereal grains and their different morphological fractions, J Agric Food Chem, 48, 2008, 10.1021/jf990619o · DOI · Paper page
- Chatha, 2006, Evaluation of the antioxidant activity of rice bran extracts using different antioxidant assays, Grasas Aceites, 57, 328, 10.3989/gya.2006.v57.i3.56 · doi:10.3989/gya.2006.v57.i3.56
- Sultana, 2009, Effect of extraction solvent/technique on the antioxidant activity of selected medicinal plant extracts, Molecules, 14, 2167, 10.3390/molecules14062167 · DOI · Paper page
- Alothman, 2009, Antioxidant capacity and phenolic content of selected tropical fruits from Malaysia, extracted with different solvents, Food Chem, 115, 785, 10.1016/j.foodchem.2008.12.005 · DOI · Paper page
- Yang, 2010, Antioxidant activities of malt extract from barley (Hordeum vulgare L.) toward various oxidative stress in vitro and in vivo, Food Chem, 118, 84, 10.1016/j.foodchem.2009.04.094 · DOI · Paper page
- Hseu, 2008, Antioxidant activities of toona sinensis leaves extracts using different antioxidant models, Food Chem Toxicol, 46, 105, 10.1016/j.fct.2007.07.003 · DOI · Paper page
- Zhu, 2011, Antioxidant activities and total phenolic contents of various extracts from defatted wheat germ, Food Chem, 126, 1122, 10.1016/j.foodchem.2010.11.144 · DOI · Paper page
- Liu, 2009, Antioxidant properties of various solvent extracts from lychee (Litchi chinenesis sonn.) flowers, Food Chem, 114, 577, 10.1016/j.foodchem.2008.09.088 · DOI · Paper page
- Wijekoon, 2011, Effect of extraction solvents on the phenolic compounds and antioxidant activities of bunga kantan (Etlingera elatior Jack.) inflorescence, J Food Compos Anal, 24, 615, 10.1016/j.jfca.2010.09.018 · DOI · Paper page
- Pinelo, 2004, Interaction among phenols in food fortification: negative synergism on antioxidant capacity, J Agric Food Chem, 52, 1177, 10.1021/jf0350515 · DOI · Paper page
- Arabshahi-D, 2007, Evaluation of antioxidant activity of some plant extracts and their heat, pH and storage stability, Food Chem, 100, 1100, 10.1016/j.foodchem.2005.11.014 · DOI · Paper page
- Robards, 2003, Strategies for the determination of bioactive phenols in plants, fruit and vegetables, J Chromatogr A, 1000, 657, 10.1016/S0021-9673(03)00058-X · DOI · Paper page
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Metadata
- Authors
- Do, Q. D., Angkawijaya, A. E., Tran-Nguyen, P. L., Huynh, L. H., Soetaredjo, F. E., Ismadji, S., & Ju, Y.-H.
- Venue
- Journal of Food and Drug Analysis
- Published
- 2014-09
- Volume
- 22
- Issue
- 3
- Pages
- 296-302
- ISSN
- 1021-9498 (ISSN-L)
- OpenAlex
- W2159548807
- Cited by
- 1,909
- References
- 0
- FWCI
- 9.86
- Type
- journal article
- Language
- en
- Open access
- hybrid
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- creativecommons.org/licenses/by-nc-nd/4.0/ (vor, 682 d)
- Funders
- National Taiwan University of Science and Technology (101H451403)
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- The paper
- Do, Q. D., Angkawijaya, A. E., Tran-Nguyen, P. L., Huynh, L. H., Soetaredjo, F. E., Ismadji, S., & Ju, Y.-H. (2014). Effect of extraction solvent on total phenol content, total flavonoid content, and antioxidant activity of Limnophila aromatica. Journal of Food and Drug Analysis. https://doi.org/10.1016/j.jfda.2013.11.001
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