Assessing transient cross-frequency coupling in EEG data
Abstract
Synchronization of oscillatory EEG signals across different frequency bands is receiving waxing interest in cognitive neuroscience and neurophysiology, and cross-frequency coupling is being increasingly linked to cognitive and perceptual processes. Several methods exist to examine cross-frequency coupling, although each has its limitations, typically by being flexible only over time or over frequency. Here, a method for assessing transient cross-frequency coupling is presented, which allows one to test for the presence of multiple, dynamic, and flexible cross-frequency coupling structure over both time and frequency. The method is applied to intracranial EEG data, and strong coupling between gamma ( approximately 40-80 Hz) and upper theta ( approximately 7-9 Hz) was observed. This method might have useful applications in uncovering the electrophysiological correlates of cognitive processes.
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- Authors
- Cohen, M. X.
- Affiliations
- University of Bonn (DE)
- Corresponding author
- Cohen, Michael X
- ORCID
- Cohen, Michael X
- Venue
- Journal of Neuroscience Methods
- Publisher
- Elsevier BV
- Published
- 2008-03
- Volume
- 168
- Issue
- 2
- Pages
- 494-499
- ISSN
- 0165-0270 (ISSN-L)
- OpenAlex
- W2002704374
- Cited by
- 262
- References
- 25
- Citations by year
- 2026: 10 · 2025: 7 · 2024: 13 · 2023: 14 · 2022: 25 · 2021: 26 · 2020: 24 · 2019: 27 · 2018: 14 · 2017: 20 · 2016: 17 · 2015: 13 · 2014: 6 · 2013: 9 · 2012: 16
- FWCI
- 1.84
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Neuroscience Methods (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cognitive Neuroscience › EEG and Brain-Computer Interfaces
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Keywords
- cross-frequency coupling, EEG synchronization, gamma oscillations, intracranial EEG, time-frequency analysis, cognitive processes
- MeSH terms
- Adult, Algorithms, Cognition, Data Interpretation, Statistical, Electrodes, Implanted, Electroencephalography, Epilepsy, Humans, Male, Perception, Theta Rhythm
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