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ASCL1- and DLX2-induced GABAergic neurons from hiPSC-derived NPCs
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“Disease-agnostic analyses reveal that transcription factors and nucleic acid binding proteins are overwhelmingly driven by LOF mutations, whereas signaling molecules, enzymes, receptors and transporters more frequently incur dominant GOF mutations55.”
From Phenotypic complexities of rare heterozygous neurexin-1 deletions (2025) · cites this paper as [55]
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Model of autism: increased ratio of excitation/inhibition in key neural systems
Rubenstein, J. L. R., & Merzenich, M. M. (2003) · Genes, Brain and Behavior · doi:10.1034/j.1601-183x.2003.00037.x · Cited by 2,768
Development and Functional Diversification of Cortical Interneurons
Lim, L., Mi, D., Llorca, A., & Marín, O. (2018) · Neuron · doi:10.1016/j.neuron.2018.10.009 · Cited by 714 · cited 1×
“Most GABAergic cortical interneurons originate from progenitors within the medial, caudal and lateral ganglion eminences (MGE, CGE, LGE) of the ventral telencephalon (Kelsom and Lu, 2013; Lim et al., 2018).”
BackgroundGenetic identification of brain cell types underlying schizophrenia
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Skene, N. G., Bryois, J., Bakken, T. E., Breen, G., Crowley, J. J., Gaspar, H. A., Giusti-Rodriguez, P., Hodge, R. D., Miller, J. A., et al. (2018) · Nature Genetics · doi:10.1038/s41588-018-0129-5 · Cited by 651
Generation of pure GABAergic neurons by transcription factor programming
Yang, N., Chanda, S., Marro, S., Ng, Y.-H., Janas, J. A., Haag, D., Ang, C. E., Tang, Y., Flores, Q., Mall, M., et al. (2017) · Nature Methods · doi:10.1038/nmeth.4291 · Cited by 341
Research works printed but not linked: 32
- Akbarian, 1995, Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics, Arch. Gen. Psychiatry, 52, 258, 10.1001/archpsyc.1995.03950160008002 · DOI · Paper page
- Al-Jaberi, 2015, The early fetal development of human neocortical GABAergic interneurons, Cereb. Cortex, 25, 631, 10.1093/cercor/bht254 · DOI
- Brennand, 2015, Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia, Mol. Psychiatry, 20, 361, 10.1038/mp.2014.22 · DOI · Paper page
- Castro, 2011, A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targets, Genes Dev., 25, 930, 10.1101/gad.627811 · DOI
- Colasante, 2015, Rapid conversion of fibroblasts into functional forebrain GABAergic interneurons by direct genetic reprogramming, Cell Stem Cell, 17, 719, 10.1016/j.stem.2015.09.002 · DOI
- Coyle, 2004, The GABA-glutamate connection in schizophrenia: which is the proximate cause?, Biochem. Pharmacol., 68, 1507, 10.1016/j.bcp.2004.07.034 · DOI
- Ho, 2016, Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells, Methods, 101, 113, 10.1016/j.ymeth.2015.11.019 · DOI · Paper page
- Ho, 2017, Evaluating synthetic activation and repression of neuropsychiatric-related genes in hiPSC-Derived NPCs, neurons, and astrocytes, Stem Cell Rep., 9, 615, 10.1016/j.stemcr.2017.06.012 · DOI
- Hoffman, 2017, Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains, Nat. Commun., 8, 2225, 10.1038/s41467-017-02330-5 · DOI
- Jacob, 2016, Cortical interneuron dysfunction in epilepsy associated with autism spectrum disorders, Epilepsia, 57, 182, 10.1111/epi.13272 · DOI
- Kanehisa, 2019, New approach for understanding genome variations in KEGG, Nucleic Acids Res., 47, D590, 10.1093/nar/gky962 · DOI
- Kelsom, 2013, Development and specification of GABAergic cortical interneurons, Cell Biosci., 3, 19, 10.1186/2045-3701-3-19 · DOI
- Kim, 2014, Efficient specification of interneurons from human Pluripotent stem cells by dorsoventral and rostrocaudal modulation, Stem Cells, 32, 1789, 10.1002/stem.1704 · DOI
- Liu, 2013, Directed differentiation of forebrain GABA interneurons from human pluripotent stem cells, Nat. Protoc., 8, 1670, 10.1038/nprot.2013.106 · DOI
- Mancarci, 2017, Cross-laboratory analysis of brain cell type transcriptomes with applications to interpretation of bulk tissue data, eNeuro, 4, 10.1523/ENEURO.0212-17.2017 · DOI
- Manuel, 2010, The transcription factor Foxg1 regulates the competence of telencephalic cells to adopt subpallial fates in mice, Development, 137, 487, 10.1242/dev.039800 · DOI
- Maroof, 2013, Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells, Cell Stem Cell, 12, 559, 10.1016/j.stem.2013.04.008 · DOI · Paper page
- Martínez, 2017, Anatomical and electrophysiological clustering of superficial medial entorhinal cortex interneurons, eNeuro, 4, 10.1523/ENEURO.0263-16.2017 · DOI
- McCarthy, 2012, Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation, Nucleic Acids Res., 40, 4288, 10.1093/nar/gks042 · DOI · Paper page
- Nicholas, 2013, Functional maturation of hPSC-Derived forebrain interneurons requires an extended timeline and mimics human neural development, Cell Stem Cell, 12, 573, 10.1016/j.stem.2013.04.005 · DOI
- O’Doherty, 2000, Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding, J. Virol., 74, 10074, 10.1128/JVI.74.21.10074-10080.2000 · DOI
- Ogata, 1999, KEGG: kyoto encyclopedia of genes and genomes, Nucleic Acids Res., 27, 29, 10.1093/nar/27.1.29 · DOI · Paper page
- Pla, 2018, Dlx1 and Dlx2 promote interneuron GABA synthesis, synaptogenesis, and dendritogenesis, Cereb. Cortex, 28, 3797, 10.1093/cercor/bhx241 · DOI
- Poitras, 2007, The proneural determinant MASH1 regulates forebrain Dlx1/2 expression through the I12b intergenic enhancer, Development, 134, 1755, 10.1242/dev.02845 · DOI
- Powell, 2017, Application of CRISPR/Cas9 to the study of brain development and neuropsychiatric disease, Mol. Cell. Neurosci., 82, 157, 10.1016/j.mcn.2017.05.007 · DOI
- Ritchie, 2015, Limma powers differential expression analyses for RNA-sequencing and microarray studies, Nucleic Acids Res., 43, e47, 10.1093/nar/gkv007 · DOI · Paper page
- Robertson, 2016, Reduced GABAergic action in the autistic brain, Curr. Biol., 26, 80, 10.1016/j.cub.2015.11.019 · DOI · Paper page
- Robinson, 2010, edgeR: a Bioconductor package for differential expression analysis of digital gene expression data, Bioinformatics, 26, 139, 10.1093/bioinformatics/btp616 · DOI · Paper page
- Ross, 2003, Basic helix-loop-Helix factors in cortical development, Neuron, 39, 13, 10.1016/S0896-6273(03)00365-9 · DOI
- Smid, 2018, Gene length corrected trimmed mean of M-values (GeTMM) processing of RNA-seq data performs similarly in intersample analyses while improving intrasample comparisons, BMC Bioinformatics, 19, 236, 10.1186/s12859-018-2246-7 · DOI
- Sun, 2016, Direct induction and functional maturation of forebrain GABAergic neurons from human pluripotent stem cells, Cell Rep., 16, 10.1016/j.celrep.2016.07.035 · DOI
- Tiscornia, 2006, Production and purification of lentiviral vectors, Nat. Protoc., 1, 241, 10.1038/nprot.2006.37 · DOI
Cited by
Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants
Zhang, S., Zhang, H., Zhou, Y., Qiao, M., Zhao, S., Kozlova, A., Shi, J., Sanders, A. R., Wang, G., Luo, K., et al. (2020) · Science · doi:10.1126/science.aay3983 · Cited by 127
Self-citationPhenotypic complexities of rare heterozygous neurexin-1 deletions
Fernando, M. B., Fan, Y., Zhang, Y., Tokolyi, A., Murphy, A. N., Kammourh, S., Deans, P. J. M., Ghorbani, S., Onatzevitch, R., Pero, A., et al. (2025) · Nature · doi:10.1038/s41586-025-08864-9 · Cited by 30
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Metadata
- Authors
- Barretto, N., Zhang, H., Powell, S. K., Fernando, M. B., Zhang, S., Flaherty, E. K., Ho, S.-M., Slesinger, P. A., Duan, J., & Brennand, K. J.
- Venue
- Journal of Neuroscience Methods
- Publisher
- Elsevier BV
- Published
- 2020-03
- Volume
- 334
- Pages
- 108548
- ISSN
- 0165-0270
- PMC
- PMC7426253
- Cited by
- 45
- References
- 4
- Language
- en
- Funders
- National Institute of Mental Health
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
