The DOI matches its Crossref record; 151 of the 151 references it cites were found in a registry or an index.
Application of nanotechnology in improving bioavailability and bioactivity of diet-derived phytochemicals
Open accessAbstract
Nanotechnology is an innovative approach that has potential applications in nutraceutical research. Phytochemicals have promising potential for maintaining and promoting health, as well as preventing and potentially treating some diseases. However, the generally low solubility, stability, bioavailability and target specificity, together with the side-effects seen when used at high levels, have limited their application. Indeed, nanoparticles can increase solubility and stability of phytochemicals, enhance their absorption, protect them from premature degradation in the body, and prolong their circulation time. Moreover, these nanoparticles exhibit high differential uptake efficiency in the target cells (or tissue) over normal cells (or tissue)through preventing them from prematurely interacting with the biological environment, enhanced permeation and retention effect in disease tissues, and improving their cellular uptake, resulting in decreased toxicity, In this review we outline the commonly used biocompatible and biodegradable nanoparticles including liposomes, emulsions, solid lipid nanoparticles, nanostructured lipid carriers, micelles and poly (lactic-co-glycolic acid) (PLGA) nanoparticles. We then summarize studies that have used these nanoparticles as carriers for EGCG, quercetin, resveratrol and curcuminadministration to enhance their aqueous solubility, stability, bioavailability, target specificity, and bioactivities.
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2 retracted
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Bioavailability of curcumin: Problems and promises
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PLGA-based nanoparticles: An overview of biomedical applications
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Cited by
Antioxidant Phytochemicals for the Prevention and Treatment of Chronic Diseases
Zhang, Y.-J., Gan, R.-Y., Li, S., Zhou, Y., Li, A.-N., Xu, D.-P., & Li, H.-B. (2015) · Molecules · doi:10.3390/molecules201219753 · Cited by 1,369
Solid Lipid Nanoparticles and Nanostructured Lipid Carriers: Structure, Preparation and Application
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Nanotechnologies in Food Science: Applications, Recent Trends, and Future Perspectives
Nile, S. H., Baskar, V., Selvaraj, D., Nile, A., Xiao, J., & Kai, G. (2020) · Nano-Micro Letters · doi:10.1007/s40820-020-0383-9 · Cited by 631
Neuropharmacological Effects of Quercetin: A Literature-Based Review
Islam, M. S., Quispe, C., Hossain, R., Islam, M. T., Al-Harrasi, A., Al-Rawahi, A., Martorell, M., Mamurova, A., Seilkhan, A., Altybaeva, N., et al. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.665031 · Cited by 165
Protective Effects of Epigallocatechin-3-Gallate from Green Tea in Various Kidney Diseases
Kanlaya, R., & Thongboonkerd, V. (2019) · Advances in Nutrition · doi:10.1093/advances/nmy077 · Cited by 99
Metadata
- Authors
- Wang, S., Su, R., Nie, S., Sun, M., Zhang, J., Wu, D., & Moustaid-Moussa, N.
- Venue
- The Journal of Nutritional Biochemistry
- Publisher
- Elsevier BV
- Published
- 2014-04
- Volume
- 25
- Issue
- 4
- Pages
- 363-376
- ISSN
- 0955-2863 (ISSN-L)
- OpenAlex
- W2125049757
- Cited by
- 531
- References
- 151
- FWCI
- 12.49
- Type
- journal article
- Language
- en
- Open access
- green
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- Wang, S., Su, R., Nie, S., Sun, M., Zhang, J., Wu, D., & Moustaid-Moussa, N. (2014). Application of nanotechnology in improving bioavailability and bioactivity of diet-derived phytochemicals. The Journal of Nutritional Biochemistry. https://doi.org/10.1016/j.jnutbio.2013.10.002
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
