Epidemiology of DSM-5 bipolar I disorder: Results from the National Epidemiologic Survey on Alcohol and Related Conditions – III

Blanco, Carlos; Compton, Wilson M.; Saha, Tulshi D.; Goldstein, Benjamin I.; Ruan, W. June; Huang, Boji; Grant, Bridget F.

doi:10.1016/j.jpsychires.2016.10.003

Cited by 150Bipolar Disorder and TreatmentPersonality Disorders and PsychopathologyMental Health Treatment and Access

Epidemiology of DSM-5 bipolar I disorder: Results from the National Epidemiologic Survey on Alcohol and Related Conditions – III

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Blanco, Carlos, Compton, Wilson M., Saha, Tulshi D., Goldstein, Benjamin I., Ruan, W. June, Huang, Boji, Grant, Bridget F.·2017·Journal of Psychiatric Research

DOI 10.1016/j.jpsychires.2016.10.003PMC PMC7416534

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Abstract

Background The objective of this study was to present 12-month and lifetime prevalence, correlates, comorbidity, treatment and disability of DSM-5 bipolar I disorder. Methods Nationally representative U.S. adult sample (N = 36,309), the 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions - III. Results Prevalences of 12-month and lifetime DSM-5 bipolar I disorder were 1.5% and 2.1% and did not differ between men (1.6% and 2.2%) and women (1.5% and 2.0%). Prevalences of bipolar I disorder were greater among Native Americans, and lower among Blacks, Hispanics and Asians/Pacific Islanders than whites. Rates were also lower among younger than older individuals, those previously married than currently married and with lower education and income relative to higher education and income. Bipolar I disorder was more strongly related to borderline and schizotypal personality disorders (adjusted odds ratios (AORS) = 2.2-4.7)), than to anxiety disorders (AORs = 1.3-2.9), and substance use disorders (AORs = 1.3-2.1) overall and among men and women. Quality of life was lower among individuals with bipolar I disorder relative to those without the disorder. Treatment rates among individuals with bipolar I disorder were low in the total sample (46%, SE = 2.63), among men (36.7%, SE = 3.82) and among women (55.8%, SE = 3.32). Conclusions Bipolar I disorder continues to be common disabling and highly comorbid disorder among men and women, contributing substantially to low quality of life and burden of disease in our society.

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Goldstein, B. I. (2012) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpediatrics.2011.832 · Cited by 45 · see citing works
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Júnior, J. C. D., Basso, L. A., Argimon, I. I. D. L., & Arteche, A. X. (2013) · Trends in Psychiatry and Psychotherapy · doi:10.1590/s2237-60892013000200002 · Cited by 44 · see citing works
Effect of First Episode Axis I Disorders on Quality of Life
Rubio, J. M., Olfson, M., Pérez-Fuentes, G., Garcı́a-Toro, M., Wang, S., & Blanco, C. (2014) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000000117 · Cited by 41 · see citing works
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The Canadian Network for Mood and Anxiety Treatments (CANMAT) task force recommendations for the management of patients with mood disorders and comorbid substance use disorders
Beaulieu, S., Saury, S., Sareen, J., Tremblay, J., Schütz, C. G., McIntyre, R. S., & Schaffer, A. (2012) · Annals of Clinical Psychiatry · doi:10.1177/104012371202400105 · Cited by 38 · see citing works
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Handbook of Diagnosis and Treatment of Bipolar Disorders
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Are there distinct biochemical subtypes of depression? EEG characteristics of clinically defined on-drug responders and non-responders
Ulrich, G., Haug, H.-J., Stieglitz, R., & Fähndrich, E. (1988) · Journal of Affective Disorders · doi:10.1016/0165-0327(88)90088-2 · Cited by 21 · see citing works
Advances in Treatment of Bipolar Disorders
(2015) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615378210 · Cited by 14 · see citing works
The Canadian Network for Mood and Anxiety Treatments (CANMAT) task force recommendations for the management of patients with mood disorders and comorbid personality disorders
Rosenbluth, M., MacQueen, G., McIntyre, R. S., Beaulieu, S., & Schaffer, A. (2012) · Annals of Clinical Psychiatry · doi:10.1177/104012371202400106 · Cited by 12 · see citing works
Late-onset Bipolar I Disorder
Salem, A., Shah, N. K., Geraldi-Samara, D., Elangovan, N., & Krzyzak, M. (2018) · Cureus · doi:10.7759/cureus.3242 · Cited by 4 · see citing works

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Epidemiology of Adult DSM-5 Major Depressive Disorder and Its Specifiers in the United States
Hasin, D. S., Sarvet, A. L., Meyers, J. L., Saha, T. D., Ruan, W. J., Stohl, M., & Grant, B. F. (2018) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2017.4602 · Cited by 1,737 · see citing works
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Bipolar disorders
Vieta, E., Berk, M., Schulze, T. G., Carvalho, A. F., Suppes, T., Calabrese, J. R., Gao, K., Miskowiak, K. W., & Grande, I. (2018) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2018.8 · Cited by 891 · see citing works
Epidemiology and risk factors for bipolar disorder
Rowland, T., & Marwaha, S. (2018) · Therapeutic Advances in Psychopharmacology · doi:10.1177/2045125318769235 · Cited by 513 · see citing works
Bipolar depression: the clinical characteristics and unmet needs of a complex disorder
McIntyre, R. S., & Calabrese, J. R. (2019) · Current Medical Research and Opinion · doi:10.1080/03007995.2019.1636017 · Cited by 211 · see citing works
Cariprazine Treatment of Bipolar Depression: A Randomized Double-Blind Placebo-Controlled Phase 3 Study
Earley, W. R., Burgess, M. V., Rekeda, L., Dickinson, R., Szatmári, B., Németh, G., McIntyre, R. S., Sachs, G. S., & Yatham, L. N. (2019) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2018.18070824 · Cited by 177 · see citing works
The Economic Burden of Bipolar Disorder in the United States: A Systematic Literature Review
Bessonova, L., Ogden, K., Doane, M. J., O'Sullivan, A. K., & Tohen, M. (2020) · ClinicoEconomics and Outcomes Research · doi:10.2147/ceor.s259338 · Cited by 147 · see citing works
Molecular Mechanisms of Bipolar Disorder: Progress Made and Future Challenges
Kim, Y., Santos, R., Gage, F. H., & Marchetto, M. C. (2017) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2017.00030 · Cited by 120 · see citing works
Polygenic risk scores for schizophrenia and bipolar disorder associate with addiction
Reginsson, G. W., Ingason, A., Euesden, J., Bjornsdottir, G., Olafsson, S., Sigurdsson, E., Oskarsson, H., Tyrfingsson, T., Runarsdottir, V., Hansdottir, I., et al. (2018) · Addiction Biology · doi:10.1111/adb.12496 · Cited by 112 · see citing works
Risk and coaggregation of major psychiatric disorders among first-degree relatives of patients with bipolar disorder: a nationwide population-based study
Chen, M.-H., Hsu, J.-W., Huang, K.-L., Su, T.-P., Li, C.-T., Lin, W.-C., Tsai, S.-J., Cheng, C.-M., Chang, W.-H., Pan, T.-L., et al. (2019) · Psychological Medicine · doi:10.1017/s003329171800332x · Cited by 106 · see citing works
Efficacy of Active vs Sham Intermittent Theta Burst Transcranial Magnetic Stimulation for Patients With Bipolar Depression: A Randomized Clinical Trial
McGirr, A., Vila-Rodriguez, F., Cole, J., Torres, I. J., Arumugham, S. S., Keramatian, K., Saraf, G., Lam, R. W., Chakrabarty, T., & Yatham, L. N. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.0963 · Cited by 76 · see citing works
Where Sex Meets Gender: How Sex and Gender Come Together to Cause Sex Differences in Mental Illness
Christiansen, D. M., McCarthy, M. M., & Seeman, M. V. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.856436 · Cited by 65 · see citing works
The importance and implications of comparator selection in pharmacoepidemiologic research
D’Arcy, M. E., Stürmer‎, T., & Lund, J. L. (2018) · Current Epidemiology Reports · doi:10.1007/s40471-018-0155-y · Cited by 59 · see citing works
Associations among Substance Use, Mental Health Disorders, and Self-Harm in a Prison Population: Examining Group Risk for Suicide Attempt
Gates, M., Turney, A., Ferguson, E., Walker, V., & Staples-Horne, M. (2017) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph14030317 · Cited by 58 · see citing works
Suicidal behavior across a broad range of psychiatric disorders
Xu, Y. E., Barron, D. A., Sudol, K., Zisook, S., & Oquendo, M. A. (2023) · Molecular Psychiatry · doi:10.1038/s41380-022-01935-7 · Cited by 58 · see citing works
Prevalence of childhood trauma among adults with affective disorder using the Childhood Trauma Questionnaire: A meta-analysis
Zhang, S., Lin, X., Yang, T., Zhang, S., Pan, Y., Lu, J., & Liu, J. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.07.001 · Cited by 49 · see citing works
Pharmacotherapeutic interventions for bipolar disorder type II: addressing multiple symptoms and approaches with a particular emphasis on strategies in lower and middle-income countries
Godman, B., Grobler, C., Van-De-Lisle, M., Wale, J., Barbosa, W. B., Massele, A. Y., Opondo, P. R., Petrova, G. I., Tachkov, K., Sefah, I. A., et al. (2019) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2019.1684473 · Cited by 48 · see citing works
Pharmacological Treatment of Mood Disorders and Comorbid Addictions: A Systematic Review and Meta-Analysis: Traitement Pharmacologique des Troubles de L’humeur et des Dépendances Comorbides: Une Revue Systématique et une Méta-Analyse
Stokes, P. R. A., Jokinen, T., Amawi, S. O., Qureshi, M. M., Husain, M. I., Yatham, L. N., Strang, J., & Young, A. H. (2020) · The Canadian Journal of Psychiatry · doi:10.1177/0706743720915420 · Cited by 46 · see citing works
Metabolic Syndrome Impairs Executive Function in Bipolar Disorder
Dalkner, N., Bengesser, S., Birner, A., Fellendorf, F. T., Fleischmann, E., Großschädl, K., Lenger, M., Maget, A., Platzer, M., Queissner, R., et al. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.717824 · Cited by 45 · see citing works
Role of obesity in systemic low-grade inflammation and cognitive function in patients with bipolar I disorder or major depressive disorder
Chen, M., Hsu, J.-W., Huang, K., Tsai, S., Su, T., Li, C., Lin, W.-C., Tu, P., & Bai, Y. (2020) · CNS Spectrums · doi:10.1017/s1092852920001534 · Cited by 43 · see citing works
Systematic literature review on patterns of pharmacological treatment and adherence among patients with bipolar disorder type I in the USA
Greene, M., Paladini, L. M., Lemmer, T., Piedade, A., Touya, M., & Clark, O. A. C. (2018) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s166730 · Cited by 44 · see citing works
The prevalence of subthreshold psychiatric symptoms and associations with alcohol and substance use disorders: from a nationally representative survey of 36,309 adults
Johnson, J. C. S., Byrne, G. J., & Pelecanos, A. M. (2022) · BMC Psychiatry · doi:10.1186/s12888-022-03834-1 · Cited by 36 · see citing works
Cancer risk in patients with bipolar disorder and unaffected siblings of such patients: A nationwide population‐based study
Chen, M., Tsai, S., Su, T., Li, C., Lin, W., Cheng, C., Chen, T., & Bai, Y. (2021) · International Journal of Cancer · doi:10.1002/ijc.33914 · Cited by 29 · see citing works
Bipolar disorder in the International Classification of Diseases-Eleventh version: A review of the changes, their basis, and usefulness
Chakrabarti, S. (2022) · World Journal of Psychiatry · doi:10.5498/wjp.v12.i12.1335 · Cited by 29 · see citing works
A pooled post hoc analysis evaluating the safety and tolerability of cariprazine in bipolar depression
Earley, W. R., Burgess, M. V., Rekeda, L., Hankinson, A. L., McIntyre, R. S., Suppes, T. M., Calabrese, J. R., & Yatham, L. N. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.11.098 · Cited by 27 · see citing works
Patterns and clinical correlates of lifetime alcohol consumption in women and men with bipolar disorder: Findings from the UK Bipolar Disorder Research Network
Gordon‐Smith, K., Lewis, K. S., Auñón, F. M. V., Florio, A. D., Perry, A., Craddock, N. J., Jones, I. R., & Jones, L. A. (2020) · Bipolar Disorders · doi:10.1111/bdi.12905 · Cited by 28 · see citing works
COVID-19: Implications for bipolar disorder clinical care and research
Xue, S., Husain, M. I., Ortiz, A., Husain, M. O., Daskalakis, Z. J., & Mulsant, B. H. (2020) · SAGE Open Medicine · doi:10.1177/2050312120981178 · Cited by 25 · see citing works
Revisiting the wandering womb: Oxytocin in endometriosis and bipolar disorder
Dinsdale, N. L., & Crespi, B. J. (2017) · Hormones and Behavior · doi:10.1016/j.yhbeh.2017.09.005 · Cited by 27 · see citing works
Chapter 44. Mood Disorders
Wai, J. M., Shulman, M., & Nunes, E. V. (2021) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615373970.kb44 · Cited by 23 · see citing works
A Randomized, Double-blind, Placebo-controlled Proof-of-Concept Trial to Evaluate the Efficacy and Safety of Non-racemic Amisulpride (SEP-4199) for the Treatment of Bipolar I Depression
Loebel, A. D., Koblan, K. S., Tsai, J., Deng, L., D, M. F. M., KENT, J. M., & Hopkins, S. C. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.09.109 · Cited by 23 · see citing works
Regulation of Inositol Biosynthesis: Balancing Health and Pathophysiology
Case, K. C., Salsaa, M., Yu, W., & Greenberg, M. L. (2018) · Handbook of experimental pharmacology · doi:10.1007/164_2018_181 · Cited by 22 · see citing works
Role of appetite hormone dysregulation in the cognitive function among patients with bipolar disorder and major depressive disorder
Chen, M., Hsu, J.-W., Huang, K., Tsai, S., Su, T., Li, C., Lin, W.-C., Tu, P., & Bai, Y. (2020) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2020.1819566 · Cited by 19 · see citing works
Psychological and behavioral response on the COVID-19 pandemic in individuals with bipolar disorder: A multicenter study
Dalkner, N., Ratzenhofer, M., Fleischmann, E., Fellendorf, F. T., Bengesser, S., Birner, A., Maget, A., Großschädl, K., Lenger, M., Platzer, M., et al. (2022) · Psychiatry Research · doi:10.1016/j.psychres.2022.114451 · Cited by 18 · see citing works
Efficacy of cariprazine in bipolar I depression across patient characteristics: a post hoc analysis of pooled randomized, placebo-controlled studies
Patel, M., Jain, R., Tohen, M. F., Maletic, V., Earley, W. R., & Yatham, L. N. (2020) · International Clinical Psychopharmacology · doi:10.1097/yic.0000000000000344 · Cited by 19 · see citing works
Inhibition of the dopamine transporter as an animal model of bipolar disorder mania: Locomotor response, neuroimmunological profile and pharmacological modulation
Bastos, J. D. R., Perico, K. M., Vieira, É. L. M., Teixeira, A. L., Machado, F. S., de Miranda, A. S., & Moreira, F. A. (2018) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2018.04.004 · Cited by 17 · see citing works
Mood Disorders
Datta, S., Suryadevara, U., & Cheong, J. (2021) · CONTINUUM Lifelong Learning in Neurology · doi:10.1212/con.0000000000001051 · Cited by 18 · see citing works
Pharmacological Treatment of Bipolar Disorder with Comorbid Alcohol Use Disorder
Naglich, A. C., Adinoff, B. H., & Brown, E. S. (2017) · CNS Drugs · doi:10.1007/s40263-017-0449-5 · Cited by 18 · see citing works
Construct validity of DSM-5 cannabis use disorder diagnosis and severity levels in adults with problematic substance use
Fink, D. S., Shmulewitz, D., Mannes, Z. L., Stohl, M., Livne, O., Wall, M. M., & Hasin, D. S. (2022) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2022.09.016 · Cited by 16 · see citing works
Candidate risk genes for bipolar disorder are highly conserved during evolution and highly interconnected
Franklin, C., & Dwyer, D. S. (2020) · Bipolar Disorders · doi:10.1111/bdi.12996 · Cited by 16 · see citing works
Acetylsalicylic Acid and Mood Disorders: A Systematic Review
Dominiak, M., Gędek, A., Sikorska, M., Mierzejewski, P., Wojnar, M., & Antosik-Wójcińska, A. Z. (2022) · Pharmaceuticals · doi:10.3390/ph16010067 · Cited by 15 · see citing works
The U-shaped relationship between parental age and the risk of bipolar disorder in the offspring: A systematic review and meta-analysis
Fico, G., Oliva, V., Prisco, M. D., Giménez‐Palomo, A., Sagué‐Vilavella, M., Gomes‐da‐Costa, S., Garriga, M., Solé, E., Valentí, M., Fanelli, G., et al. (2022) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2022.05.004 · Cited by 15 · see citing works
Home-based transcranial direct current stimulation in bipolar depression: an open-label treatment study of clinical outcomes, acceptability and adverse events
Ghazi-Noori, A.-R., Woodham, R. D., Rezaei, H., Sharif, M. S., Bramon, E., Ritter, P. S., Bauer, M., Young, A. H., & Fu, C. H. Y. (2024) · International Journal of Bipolar Disorders · doi:10.1186/s40345-024-00352-9 · Cited by 14 · see citing works
Bipolar and Related Disorders
(2022) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9780890425787.x03_bipolar_and_related_disorders · Cited by 14 · see citing works
Predictors of quality of life in bipolar disorder: A path analytical study
Cotrena, C., Branco, L. D., Shansis, F., & Fonseca, R. P. (2020) · Psychiatry Research · doi:10.1016/j.psychres.2020.112846 · Cited by 14 · see citing works
Effectiveness of Repetitive Transcranial Magnetic Stimulation in the Treatment of Bipolar Disorder in Comparison to the Treatment of Unipolar Depression in a Naturalistic Setting
Alhelali, A., Almheiri, E., Abdelnaim, M. A., Weber, F. C., Langguth, B., Schecklmann, M., & Hebel, T. (2022) · Brain Sciences · doi:10.3390/brainsci12030298 · Cited by 14 · see citing works
Culturally competent, safe and equitable clinical care for Ma¯ori with bipolar disorder in New Zealand: The expert critique of Ma¯ori patients and Wha¯nau
Haitana, T., Pitama, S. G., Cormack, D. M., Clark, M. T. R., & Lacey, C. J. (2021) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/00048674211031490 · Cited by 14 · see citing works
Are caregivers ready for digital? Caregiver preferences for health technology tools to monitor medication adherence among patients with serious mental illness
Forma, F. M., Chiu, K., Shafrin, J. T., Boskovic, D. H., & Veeranki, S. P. (2022) · Digital Health · doi:10.1177/20552076221084472 · Cited by 12 · see citing works
‘It absolutely needs to move out of that structure’: Māori with bipolar disorder identify structural barriers and propose solutions to reform the New Zealand mental health system
Haitana, T., Pitama, S. G., Cormack, D. M., Clark, M. T. R., & Lacey, C. J. (2022) · Ethnicity and Health · doi:10.1080/13557858.2022.2027884 · Cited by 12 · see citing works
Fire and Darkness: On the Assessment and Management of Bipolar Disorder
Nikolitch, K., Saraf, G., Solmi, M., Kroenke, K., & Fiedorowicz, J. G. (2022) · Medical Clinics of North America · doi:10.1016/j.mcna.2022.04.002 · Cited by 12 · see citing works
Racial differences in the major clinical symptom domains of bipolar disorder
Li, K. D., Richards, E. M., & Goes, F. S. (2023) · International Journal of Bipolar Disorders · doi:10.1186/s40345-023-00299-3 · Cited by 11 · see citing works
Emotional regulation neural circuitry abnormalities in adult bipolar disorder: dissociating effects of long-term depression history from relationships with present symptoms
Bertocci, M. A., Bergman, J., Santos, J. P. L., Iyengar, S., Bonar, L. K., Gill, M. K., Abdul‐waalee, H., Bebko, G. M., Stiffler, R. S., Lockovich, J., et al. (2020) · Translational Psychiatry · doi:10.1038/s41398-020-01048-1 · Cited by 11 · see citing works
Cariprazine as a Treatment Option for Depressive Episodes Associated with Bipolar 1 Disorder in Adults: An Evidence-Based Review of Recent Data
Tohen, M. F. (2021) · Drug Design Development and Therapy · doi:10.2147/dddt.s240860 · Cited by 11 · see citing works
Co-occurring Mood and Substance Use Disorders
Wai, J. M., Shulman, M., Nunes, E. V., Hasin, D. S., & Weiss, R. D. (2020) · Springer eBooks · doi:10.1007/978-3-030-36391-8_91 · Cited by 11 · see citing works
The course of bipolar disorder as a function of the presence and sequence of onset of comorbid alcohol use disorders in outpatients attending the Fondamental Advanced Centres of Expertise
Icick, R., Gard, S., M’Baïlara, K., Biseul, I., Samalin, L., Brousse, G., Flaudias, V., Llorca, P., Loftus, J., Cussac, I., et al. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.03.041 · Cited by 11 · see citing works
Real-World Patterns of Utilization and Costs Associated with Second-Generation Oral Antipsychotic Medication for the Treatment of Bipolar Disorder: A Literature Review
Doane, M. J., Ogden, K., Bessonova, L., O’Sullivan, A. K., & Tohen, M. F. (2021) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s280051 · Cited by 10 · see citing works
Percutaneous transport of psychotropic agents
Ita, K. B. (2017) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2017.04.009 · Cited by 10 · see citing works
Bipolar disorder and addictions: The elephant in the room
Stokes, P. R. A., Kalk, N. J., & Young, A. H. (2017) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.116.193912 · Cited by 10 · see citing works
Timing of risk factors, prodromal features, and comorbidities of dementia from a large health claims case–control study
Teipel, S. J., Akmatov, M. K., Michalowsky, B., Riedel-Heller, S. G., Bohlken, J., & Holstiege, J. (2025) · Alzheimer s Research & Therapy · doi:10.1186/s13195-024-01662-x · Cited by 9 · see citing works
An epidemiological profile of bipolar disorder among older adults with complex needs: A national cross‐sectional study
Schlüter, P. J., Lacey, C. J., Porter, R., & Jamieson, H. A. (2017) · Bipolar Disorders · doi:10.1111/bdi.12511 · Cited by 8 · see citing works
Real-world retrospective study of repetitive transcranial magnetic stimulation (TMS) treatment for bipolar and unipolar depression using TMS registry data in Tokyo
Ikawa, H., Osawa, R., Takeda, Y., Sato, A., Mizuno, H., & Noda, Y. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e27288 · Cited by 8 · see citing works
Ethanol-induced cognitive dysfunction is associated with alterations in the mammalian target of rapamycin signalling pathway in the hippocampus of male mice
Yang, X., & Zou, D. (2018) · Neuroreport · doi:10.1097/wnr.0000000000001104 · Cited by 8 · see citing works
Believing processes during the COVID-19 pandemic in individuals with bipolar disorder: An exploratory study
Tietz, S., Wagner‐Skacel, J., Angel, H., Ratzenhofer, M., Fellendorf, F. T., Fleischmann, E., Körner, C., Reininghaus, E. Z., Seitz, R. J., & Dalkner, N. (2022) · World Journal of Psychiatry · doi:10.5498/wjp.v12.i7.929 · Cited by 9 · see citing works
Cost–effectiveness of long-acting injectable aripiprazole once-monthly 400 mg in bipolar I disorder in the USA
Augusto, M., Greene, M., Touya, M., Sweeney, S. M., & Waters, H. C. (2018) · Journal of Comparative Effectiveness Research · doi:10.2217/cer-2018-0010 · Cited by 8 · see citing works
Efficacy, Effectiveness, and Safety of Transcranial Magnetic Stimulation for Bipolar Depression: A Systematic Review and Meta-Analysis
Ventura, F., Frias, P., da Silva, D. R., McGirr, A., Cotovio, G., & Oliveira-Maia, A. J. (2025) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2025.100618 · Cited by 7 · see citing works
Why religion and spirituality are important in human biological research
Lynn, C. D., & Schell, L. M. (2024) · American Journal of Human Biology · doi:10.1002/ajhb.24106 · Cited by 8 · see citing works
Cannabis use and social anxiety disorder in emerging adulthood: Results from a nationally representative sample
Single, A. N., Alcolado, G. M., Keough, M. T., & Mota, N. P. (2023) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2023.102808 · Cited by 7 · see citing works
Physical and mental health status of former smokers and non‐smokers patients with bipolar disorder
Nobile, B., Godin, O., Gard, S., Samalin, L., Brousse, G., Loftus, J., Aubin, V., Belzeaux-R, R., Dubertret, C., Strat, Y. L., et al. (2023) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.13535 · Cited by 7 · see citing works
Genetics of Bipolar Spectrum Disorders: Focus on Family Studies Using Whole Exome Sequencing
Kasyanov, E. D., Merkulova, T. V., Kibitov, A. O., & Mazo, G. E. (2020) · Russian Journal of Genetics · doi:10.1134/s1022795420070054 · Cited by 6 · see citing works
Long-Term Healthcare Utilization and the Cost of Bipolar Disorder Among Participants in a Large Employer's Health Benefit Plan
Leung, N., Bernacki, S. E., Kalia, N., Bernacki, E. J., & Almeida, J. R. C. (2021) · Journal of Occupational and Environmental Medicine · doi:10.1097/jom.0000000000002465 · Cited by 7 · see citing works
Differences in intracellular protein levels in monocytes and CD4+ lymphocytes between bipolar depressed patients and healthy controls: A pilot study with tyramine-based signal-amplified flow cytometry
Gao, K., Ayati, M., Kaye, N. M., Koyutürk, M., Calabrese, J. R., Ganocy, S. J., Lazarus, H. M., Christian, E., & Kaplan, D. R. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.02.058 · Cited by 6 · see citing works
Clinical characteristics and impacts of HIV infection in people with bipolar disorders
Yalın, N., Conti, I., Bagchi, S., Essig, A., Bird, C., Adlington, K., Everall, I., & Stokes, P. R. A. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.07.077 · Cited by 6 · see citing works
Place of care and costs associated with acute episodes and remission in bipolar I disorder
McIntyre, R. S., Higa, S., Doan, Q. V., Amari, D. T., Oliveri, D., Gillard, P. J., & Harrington, A. (2022) · Journal of Medical Economics · doi:10.1080/13696998.2022.2120264 · Cited by 6 · see citing works
Editorial: Comorbidity in bipolar disorder and schizophrenia, volume III
Martinotti, G., Fornaro, M., & Berardis, D. D. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1356817 · Cited by 6 · see citing works
Budget impact analysis of long-acting injectable aripiprazole once-monthly 400 mg in bipolar I disorder in the USA
Augusto, M., Greene, M., Touya, M., Sweeney, S. M., & Waters, H. C. (2018) · Journal of Comparative Effectiveness Research · doi:10.2217/cer-2018-0009 · Cited by 5 · see citing works
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Authors: Blanco, C., Compton, W. M., Saha, T. D., Goldstein, B. I., Ruan, W. J., Huang, B., & Grant, B. F.
Affiliations: National Institute on Drug Abuse (US)
National Institutes of Health (US)
Sunnybrook Health Science Centre (CA)
Corresponding author: Saha, Tulshi D.
ORCID: Blanco, Carlos
Compton, Wilson M.
Goldstein, Benjamin I.
Ruan, W. June
Venue: Journal of Psychiatric Research
Publisher: Elsevier BV
Published: 2017-01
Volume: 84
Pages: 310-317
ISSN: 0022-3956 (ISSN-L)
DOI: 10.1016/j.jpsychires.2016.10.003
PMC: PMC7416534
OpenAlex: W2529367653
Cited by: 149
References: 85
Citations by year: 2026: 13 · 2025: 16 · 2024: 18 · 2023: 10 · 2022: 23 · 2021: 18 · 2020: 17 · 2019: 9 · 2018: 16 · 2017: 8
FWCI: 9.77
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Journal of Psychiatric Research (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute on Alcohol Abuse and Alcoholism
National Institute on Drug Abuse
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
Keywords: bipolar I disorder, prevalence, DSM-5, comorbidities, borderline personality disorder, schizotypal personality disorder, substance use disorders, anxiety disorders, quality of life, treatment rates, disability, socioeconomic factors, racial and ethnic disparities, sex differences, NESARC
MeSH terms: Adolescent, Adult, Age Factors, Aged, Bipolar Disorder, Disability Evaluation, Female, Humans, Interview, Psychological, Male, Middle Aged, Quality of Life, Sex Factors, Socioeconomic Factors, United States, Comorbidity, Prevalence, Diagnostic and Statistical Manual of Mental Disorders, Young Adult

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Epidemiology of DSM-5 bipolar I disorder: Results from the National Epidemiologic Survey on Alcohol and Related Conditions – III

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