Cited by 16Psychotherapy Techniques and ApplicationsAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesMusculoskeletal pain and rehabilitation

Randomized controlled trial of interpersonal psychotherapy versus enhanced treatment as usual for women with co-occurring depression and pelvic pain

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Poleshuck, Ellen L., Gamble, Stephanie A., Bellenger, Kelly, Lu, Naiji, Tu, Xin, Sörensen, Silvia, Giles, Donna E., Talbot, Nancy L.·2014·Journal of Psychosomatic Research

Abstract

Objective Our study assessed the effectiveness of Interpersonal Psychotherapy (IPT) tailored for biomedical patients with depression and pain. IPT was compared to enhanced treatment as usual (E-TAU) among women with co-occurring depression and chronic pain presenting for care at a women's health or family medicine practice. We hypothesized that women presenting to urban medical practices with depression and chronic pain would benefit from IPT tailored to address their needs to a greater degree than from E-TAU.Methods We conducted a randomized controlled psychotherapy trial of 61 women from 2 urban medical practices who met criteria for major depressive disorder and chronic pelvic pain. Participants were assigned to receive either 8 sessions of IPT or a facilitated psychotherapy referral to a community mental health center, and assessed for depression, social interactions, and pain at 0-, 12-, 24-, and 36-weeks, with score on the Hamilton Rating Scale for Depression as the primary outcome. Both intent-to-treat (ITT) and causal modeling analyses correcting for treatment attendance were conducted.Results ITT analyses were not significant. In causal modeling analyses, participants assigned to IPT showed significantly more improvement for depression and social interactions, but not for pain.Conclusion IPT may be a viable option as part of a comprehensive treatment program for women in medical practices with depression and chronic pain.Clinical trials registration ClinicalTrials.gov, NCT00895999.

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Crossref · 10.1016/j.jpsychores.2014.07.016

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  • In Poleshuck et al. (2014), at post-treatment, compared to E-TAU, the IPT-P group had significantly lower occurrence of MDD (estimate = .19, SE = .10, P < .05).

    “- occurrence of MDD (estimate = .19, SE = .10, P < .05)”

    From The Effectiveness of Interventions for Improving Chronic Pain Symptoms Among People With Mental Illness: A Systematic Review (2024) · cites this paper as Poleshuck et al, (2014)

    The Results > Outcomes section says the causal models found significantly lower post-treatment occurrence of major depressive disorder in the IPT-P group than in E-TAU. It also says the intent-to-treat analysis found no significant effect, so the result depends on the causal-model analysis. The passages available from our copy do not verify the stated estimate of .19 or SE of .10. (LLM, conf=0.85)

    Experimental — accuracy not yet measured
  • In Poleshuck et al. (2014), there was no significant between-group difference on pain interference at post-treatment (estimate = .33, SE = -.20, P > .05).

    “- pain interference (estimate = .33, SE = -.20, P > .05) at post-treatment”

    From The Effectiveness of Interventions for Improving Chronic Pain Symptoms Among People With Mental Illness: A Systematic Review (2024) · cites this paper as Poleshuck et al, (2014)

    The Results > Outcomes section says the causal models found no significant between-group difference for pain at post-treatment, and the Methods section identifies pain interference as a measured outcome. The passages do not report the claimed estimate or standard error; in particular, they do not substantiate the negative value given for SE. (LLM, conf=0.86)

    Experimental — accuracy not yet measured
  • In Poleshuck et al. (2014), at post-treatment, compared to E-TAU, the IPT-P group had significantly lower adjusted depression scores (estimate = 2.13, SE = 1.05 P < .05 for HRSD; estimate = 3.89, SE = 2.19, P < .05 for BDI).

    “At post-treatment, compared to E-TAU, the IPT-P group had significantly lower - adjusted depression scores (estimate = 2.13, SE = 1.05 P < .05 for HRSD; estimate = 3.89, SE = 2.19, P < .05 for BDI)”

    From The Effectiveness of Interventions for Improving Chronic Pain Symptoms Among People With Mental Illness: A Systematic Review (2024) · cites this paper as Poleshuck et al, (2014)

    The Results > Outcomes section reports that, in causal-model analyses, IPT-P participants had significantly lower adjusted depression scores than E-TAU participants at post-treatment. Our copy does not provide the quoted HRSD and BDI estimates, standard errors, or individual P values, so those numbers cannot be verified. The same section notes that the intent-to-treat analyses found no significant intervention effects. (LLM, conf=0.86)

    Experimental — accuracy not yet measured
  • Additional improvements in illness impact, social interactions, as well as interpersonal sensitivity and ambivalence were found.

    “Other tertiary outcomes were examined in 8 out of 11 trials. Improved QoL was reported in 5 out of 6 trials. 21,22,25,32,42 Additional improvements in illness impact, social interactions, 42 as well as interpersonal sensitivity and ambivalence 31 were found, but these outcomes were only reported in 1 RCT.”
  • Only one trial evaluated IPT and included a sample of less than 100.

    “with only one trial evaluating an IPT 31 and including a sample of less than 100”

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Cites

1 retracted

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Research works printed but not linked: 1

  1. [41]First MB, Spitzer RL, Gibbon M, Williams JBW, and Benjamin L (1996). User’s Guide for the Structured Clinical Interview for DSM-IV Personality Disorders (SCID II). Washington DC: American Psychiatric Press Inc.

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Authors
Poleshuck, E. L., Gamble, S. A., Bellenger, K., Lu, N., Tu, X., Sörensen, S., Giles, D. E., & Talbot, N. L.
Affiliations
University of Rochester Medicine (US)
Corresponding author
Poleshuck, Ellen L.
Venue
Journal of Psychosomatic Research
Publisher
Elsevier BV
Published
2014-10
Volume
77
Issue
4
Pages
264-272
ISSN
0022-3999 (ISSN-L)
OpenAlex
W2034588706
Cited by
16
References
62
Citations by year
2026: 1 · 2025: 3 · 2024: 1 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 1 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 3
FWCI
1.58
Type
journal article
Language
en
Open access
Locations
  • Journal of Psychosomatic Research (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institute of Mental Health (K23-MH079347)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
Keywords
interpersonal psychotherapy, depression, chronic pelvic pain, women's health, usual care, social interaction, pain intensity, primary care
MeSH terms
Adult, Depression, Depressive Disorder, Major, Major Depressive Disorder, Family Practice, Female, Humans, Interpersonal Relations, Middle Aged, Psychotherapy, Surveys and Questionnaires, Research Design, Severity of Illness Index, Time Factors, Urban Population, Comorbidity, Treatment Outcome, Pelvic Pain, Chronic Pain

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