Supplementation with a whey protein hydrolysate enhances recovery of muscle force-generating capacity following eccentric exercise
Abstract
There is evidence that protein hydrolysates can speed tissue repair following damage and may therefore be useful for accelerating recovery from exercise induced muscle damage. The potential for a hydrolysate (WPI(HD)) of whey protein isolate (WPI) to speed recovery following eccentric exercise was evaluated by assessing effects on recovery of peak isometric torque (PIT). In a double-blind randomised parallel trial, 28 sedentary males had muscle soreness (MS), serum creatine kinase (CK) activity, plasma TNFalpha, and PIT assessed at baseline and after 100 maximal eccentric contractions (ECC) of their knee extensors. Participants then consumed 250 ml of flavoured water (FW; n=11), or FW containing 25 g WPI (n=11) or 25 g WPI(HD) (n=6) and the assessments were repeated 1, 2, 6 and 24h later. PIT decreased approximately 23% following ECC, remained suppressed in FW and WPI, but recovered fully in WPI(HD) by 6h (P=0.006, treatment x time interaction). MS increased following ECC (P<0.001 for time), and remained elevated with no difference between groups (P=0.61). TNFalpha and CK did not change (P>0.45). WPI(HD) may be a useful supplement for assisting athletes to recover from fatiguing eccentric exercise.
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A ~30 g dose of a hydrolyzed whey protein isolate resulted in a more rapid recovery of muscle force-generating capacity following eccentric exercise, compared with a flavored water placebo or a non-hydrolyzed form of the same whey protein isolate.
“Buckley and colleagues [207] found that a ~ 30 g dose of a hydrolyzed whey protein isolate resulted in a more rapid recovery of muscle force-generating capacity following eccentric exercise, compared with a flavored water placebo or a non-hydrolyzed form of the same whey protein isolate.”
From International Society of Sports Nutrition Position Stand: protein and exercise (2017) · cites this paper as [207]
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“Buckley and colleagues [207] found that a ~ 30 g dose of a hydrolyzed whey protein isolate resulted in a more rapid recovery of muscle force-generating capacity following eccentric exercise, compared with a flavored water placebo or a non-hydrolyzed form of the same whey protein isolate.”
BackgroundInternational Society of Sports Nutrition position stand: protein and exercise
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- Authors
- Buckley, J. D., Thomson, R. L., Coates, A. M., Howe, P. R. C., DeNichilo, M. O., & Rowney, M. K.
- Affiliations
- University of South Australia (AU)
- Venue
- Journal of Science and Medicine in Sport
- Publisher
- Elsevier BV
- Published
- 2010-01
- Volume
- 13
- Issue
- 1
- Pages
- 178-181
- ISSN
- 1440-2440 (ISSN-L)
- OpenAlex
- W2047519843
- Cited by
- 164
- References
- 0
- Citations by year
- 2026: 10 · 2025: 5 · 2024: 4 · 2023: 29 · 2022: 4 · 2021: 10 · 2020: 13 · 2019: 13 · 2018: 10 · 2017: 13 · 2016: 8 · 2015: 9 · 2014: 10 · 2013: 4 · 2012: 4
- FWCI
- 2.47
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of science and medicine in sport (publishedVersion)
- PubMed (publishedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- Funders
- Division of Electrical, Communications and Cyber Systems
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
- Keywords
- whey protein hydrolysate, whey protein isolate, exercise-induced muscle damage, eccentric exercise, muscle recovery, muscle soreness, creatine kinase, TNF-α, isometric torque, knee extensors, dietary supplementation
- MeSH terms
- Whey Proteins, Adolescent, Adult, Analysis of Variance, Creatine Kinase, Double-Blind Method, Exercise Test, Physical Exertion, Humans, Isometric Contraction, Knee Joint, Male, Milk Proteins, Pain Measurement, Exercise, Muscle, Skeletal, Muscle Fatigue, Muscle Strength Dynamometer, Young Adult
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