Improving patient adherence: a three-factor model to guide practice

DiMatteo, M. Robin; Haskard-Zolnierek, Kelly B.; Martin, Leslie R.

doi:10.1080/17437199.2010.537592

Cited by 288Medication Adherence and CompliancePatient-Provider Communication in HealthcareDiabetes Management and Education

Improving patient adherence: a three-factor model to guide practice

DiMatteo, M. Robin, Haskard-Zolnierek, Kelly B., Martin, Leslie R.·2012·Health Psychology Review

DOI 10.1080/17437199.2010.537592

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Abstract

Patient nonadherence is widespread and costly. This paper provides a brief narrative review of research on (non)adherence and validates a clinically useful three-factor heuristic model to guide practitioners as they work with patients to improve adherence. This model is based on the most stable findings from meta-analyses and large-scale empirical studies, reflects the realities of medical practice and offers recommendations for assessing and enhancing patient adherence, particularly in chronic disease management. The model comprises three important clinical actions: (1) insuring that patients have the right information and know how to adhere – including listening to patients’ concerns, encouraging their participation and partnership in decision-making, building trust and empathy, and enhancing recall; (2) helping patients believe in their treatment and become motivated to commit to it – that is, addressing the cognitive, social, cultural normative and contextual factors that affect patients’ beliefs, attitudes and motivation; and (3) assisting patients to overcome practical barriers to treatment adherence and develop a workable strategy for long-term disease management – including assessing and enhancing patients’ social support, identifying and treating their depression and helping patients overcome cost-related treatment barriers.

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The association between medication-adherence behaviours and health outcomes can vary by disease and by the suitability and efficacy of the prescribed treatment.
“As Di Matteo, Haskard-Zolnierek and Martin (2012) point out, the correlation between the behaviours involved in medication adherence and health outcomes may vary with the disease condition and the appropriateness and efficacy of the treatment prescribed.”
From Theories and techniques of behaviour change: Developing a cumulative science of behaviour change (2012) · cites this paper as Di Matteo, Haskard-Zolnierek and Martin (2012)
Adherence has a significant effect on treatment outcomes and a major impact in managing chronic conditions such as hypertension, cardiovascular disease, and diabetes.
“Adherence has been shown to have a significant effect on treatment outcomes [3,4] and has a major impact in managing chronic conditions such as hypertension, cardiovascular disease, and diabetes.”
From Impact of Social Determinants of Health and Demographics on Refill Requests by Medicare Patients Using a Conversational Artificial Intelligence Text Messaging Solution: Cross-Sectional Study (2019) · cites this paper as [4]

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Authors: DiMatteo, M. R., Haskard-Zolnierek, K. B., & Martin, L. R.
Affiliations: University of California, Riverside (US)
La Sierra University (US)
Corresponding author: Martin, Leslie R.
ORCID: Martin, Leslie R.
Venue: Health Psychology Review
Publisher: Informa UK Limited
Published: 2012-03
Volume: 6
Issue: 1
Pages: 74-91
ISSN: 1743-7199 (ISSN-L)
1743-7202
DOI: 10.1080/17437199.2010.537592
OpenAlex: W1970746596
Cited by: 288
References: 114
Citations by year: 2026: 14 · 2025: 25 · 2024: 17 · 2023: 13 · 2022: 29 · 2021: 24 · 2020: 21 · 2019: 15 · 2018: 24 · 2017: 21 · 2016: 22 · 2015: 26 · 2014: 18 · 2013: 13 · 2012: 5
FWCI: 10.89
Type: journal article
Language: en
Open access: closed
Locations: Health Psychology Review (publishedVersion)
Topics: Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
Health Sciences › Health Professions › General Health Professions › Patient-Provider Communication in Healthcare
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
Keywords: medication adherence, patient non-adherence, three-factor model, chronic disease management, patient-provider communication, shared decision-making, treatment motivation, social support, depression, patient recall, health beliefs and attitudes

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Improving patient adherence: a three-factor model to guide practice

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