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Cited by 482

The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.

Iron management in chronic kidney disease: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference

Open access
Macdougall, Iain C., Bircher, Andreas J., Eckardt, Kai-Uwe, Obrador, Gregorio T., Pollock, Carol A., Stenvinkel, Peter, Swinkels, Dorine W., Wanner, Christoph, Weiss, Günter, Chertow, Glenn M., Adamson, John W., Akizawa, Tadao, Anker, Stefan D., Auerbach, Michael, Bárány, Peter, Besarab, Anatole, Bhandari, Sunil, Cabantchik, Ioav, Collins, Alan J., Coyne, Daniel W., de Francisco, Ángel L.M., Fishbane, Steven, Gaillard, Carlo A.J.M., Ganz, Tomas, Goldsmith, David J., Hershko, Chaim, Jankowska, Ewa A., Johansen, Kirsten L., Kalantar-Zadeh, Kamyar, Kalra, Philip A., Kasiske, Bertram L., Locatelli, Francesco, Małyszko, Jolanta, Mayer, Gert, McMahon, Lawrence P., Mikhail, Ashraf, Nemeth, Elizabeta, Pai, Amy Barton, Parfrey, Patrick S., Pecoits-Filho, Roberto, Roger, Simon D., Rostoker, Guy, Rottembourg, Jacques, Singh, Ajay K., Slotki, Itzchak, Spinowitz, Bruce S., Tarng, Der-Cherng, Tentori, Francesca, Toblli, Jorge E., Tsukamoto, Yusuke, Vaziri, Nosratola D., Winkelmayer, Wolfgang C., Wheeler, David C., Zakharova, Elena·2016·Kidney International
DOI 10.1016/j.kint.2015.10.002
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Abstract

Before the introduction of erythropoiesis-stimulating agents (ESAs) in 1989, repeated transfusions given to patients with end-stage renal disease caused iron overload, and the need for supplemental iron was rare. However, with the widespread introduction of ESAs, it was recognized that supplemental iron was necessary to optimize hemoglobin response and allow reduction of the ESA dose for economic reasons and recent concerns about ESA safety. Iron supplementation was also found to be more efficacious via intravenous compared to oral administration, and the use of intravenous iron has escalated in recent years. The safety of various iron compounds has been of theoretical concern due to their potential to induce iron overload, oxidative stress, hypersensitivity reactions, and a permissive environment for infectious processes. Therefore, an expert group was convened to assess the benefits and risks of parenteral iron, and to provide strategies for its optimal use while mitigating the risk for acute reactions and other adverse effects.

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Metadata

Authors
Macdougall, I. C., Bircher, A. J., Eckardt, K.-U., Obrador, G. T., Pollock, C. A., Stenvinkel, P., Swinkels, D. W., Wanner, C., Weiss, G., Chertow, G. M., Adamson, J. W., Akizawa, T., Anker, S. D., Auerbach, M., Bárány, P., Besarab, A., Bhandari, S., Cabantchik, I., Collins, A. J., Coyne, D. W., de Francisco, Á. L. M., Fishbane, S., Gaillard, C. A. J. M., Ganz, T., Goldsmith, D. J., Hershko, C., Jankowska, E. A., Johansen, K. L., Kalantar-Zadeh, K., Kalra, P. A., Kasiske, B. L., Locatelli, F., Małyszko, J., Mayer, G., McMahon, L. P., Mikhail, A., Nemeth, E., Pai, A. B., Parfrey, P. S., Pecoits-Filho, R., Roger, S. D., Rostoker, G., Rottembourg, J., Singh, A. K., Slotki, I., Spinowitz, B. S., Tarng, D.-C., Tentori, F., Toblli, J. E., Tsukamoto, Y., Vaziri, N. D., Winkelmayer, W. C., Wheeler, D. C., & Zakharova, E.
Venue
Kidney International
Publisher
Elsevier BV
Published
2016-01
Volume
89
Issue
1
Pages
28-39
ISSN
0085-2538 (ISSN-L)
DOI
10.1016/j.kint.2015.10.002
OpenAlex
W2222807855
Cited by
482
References
52
FWCI
35.02
Type
journal article
Language
en
Open access
hybrid

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