Role of glucocorticoids in dopamine-related neuropsychiatric disorders
Abstract
'Psychoneuroendocrinology' is now quickly emerging as a hot interdisciplinary research field that addresses the interplay between neuronal and endocrine signaling in psychiatric diseases. Both glucocorticoid hormones and dopamine have an important role in maintaining normal brain functions. In this review, molecular and mechanistic aspects of glucocorticoid effects on brain function and behavior will be discussed with specific reference to dopamine signaling.
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Receptors for CRF and glucocorticoids are distributed throughout the brain's reward circuitry, and their activation or blockade influences reward-related neurotransmission and behavior.
“receptors for CRF and glucocorticoids are located throughout the reward circuitry of the brain, with their activation or blockade affecting reward-sensitive neurotransmission and behaviors (Bryce and Floresco, 2016; Craenenbroeck et al., 2005; Walsh et al., 2014).”
From The effects of early life stress on reward processing (2018) · cites this paper as Craenenbroeck et al., 2005
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Boika, A. V., Ponomarev, V. V., Mazurenka, K., & Михневич, И. И. (2018) · Journal of the Grodno State Medical University · doi:10.25298/2221-8785-2018-16-2-159-164 · Cited by 1 · see citing works
Omega‐3, 6 and 9 Fatty Acids, Inflammation and Neurodegenerative Diseases
Song, C. (2010) · doi:10.1002/9781444323351.ch19 · Cited by 1 · see citing works
Jones‐Mason, K. (2011) · eScholarship (California Digital Library) · Cited by 1 · see citing works
Smaga, I., Krzyżanowska, W., Pomierny, B., Maciejska, A., Skórkowska, A., Budziszewska, B., Pilc, A., & Nowak, G. (2021) · Springer eBooks · doi:10.1007/978-3-030-71519-9_176-1
Behavioral medical epigenetics
Cox, O., & Lee, R. S. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-823928-5.00017-7
- Authors
- Craenenbroeck, K. V., Bosscher, K. D., Berghe, W. V., Vanhoenacker, P., & Haegeman, G.
- Affiliations
- Ghent University (BE)
- Corresponding author
- Haegeman, Guy
- Venue
- Molecular and Cellular Endocrinology
- Publisher
- Elsevier BV
- Published
- 2005-12
- Volume
- 245
- Issue
- 1-2
- Pages
- 10-22
- ISSN
- 0303-7207 (ISSN-L)
- OpenAlex
- W2002630309
- Cited by
- 64
- References
- 147
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 3 · 2022: 3 · 2021: 4 · 2020: 3 · 2019: 1 · 2018: 6 · 2016: 6 · 2015: 2 · 2014: 7 · 2013: 7 · 2012: 2
- FWCI
- 0.13
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Molecular and Cellular Endocrinology (publishedVersion)
- PubMed (publishedVersion)
- Ghent University Academic Bibliography (Ghent University) (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- glucocorticoids, dopamine signaling, neuropsychiatric disorders, psychoneuroendocrinology, brain function, behavior, neuroendocrine signaling, glucocorticoid receptor
- MeSH terms
- Animals, Mental Disorders, Depressive Disorder, Major, Major Depressive Disorder, Dopamine, Gene Expression Regulation, Glucocorticoids, Humans, Parkinson Disease, Receptors, Dopamine, Receptors, Glucocorticoid, Schizophrenia, Signal Transduction, Behavior, Addictive, Neurotransmitter Agents, Receptor Cross-Talk, Epigenesis, Genetic
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