The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Soy, phytoestrogens and metabolism: A review
Open accessAbstract
Of any plant, soy contains the largest concentration of isoflavones, a class of phytoestrogens. Phytoestrogens are structurally similar to estradiol and mimic its effects. Soy and phytoestrogens receive increasing attention due to the health benefits associated with their consumption. Here we review the data collected on the effects of soy and phytoestrogens on glucose and lipid metabolism and their possible mechanisms of action. Overall, there is a suggestive body of evidence that soy and dietary phytoestrogens favorably alter glycemic control, improve weight and fat loss, lower triglycerides, low density lipoprotein (LDL) cholesterol and total cholesterol. However, these results must be interpreted with care, and additional evidence is needed before a firm conclusion can be drawn. In particular, since not all activities related to soy can be assigned to the estrogenic-like activity, further studies are needed to identify firstly which soy constituent(s) improve metabolic parameters when ingested and secondly, which are the mechanisms whereby dietary soy improves metabolic-related conditions like obesity and diabetes. Finally, the potential detrimental effects of soy and phytoestrogens are briefly discussed.
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Cites
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Cited by
Serum level of sex steroid hormone is associated with diversity and profiles of human gut microbiome
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Systematic review and meta-analysis on the effect of soy on thyroid function
Otun, J., Sahebkar, A., Östlundh, L., Atkin, S. L., & Sathyapalan, T. (2019) · Scientific Reports · doi:10.1038/s41598-019-40647-x · Cited by 68
Nozue, M., Shimazu, T., Sasazuki, S., Charvat, H., Mori, N., Mutoh, M., Sawada, N., Iwasaki, M., Yamaji, T., Inoue, M., et al. (2017) · The Journal of Nutrition · doi:10.3945/jn.117.250282 · Cited by 66
Metadata
- Authors
- Cederroth, C. R., & Nef, S.
- Venue
- Molecular and Cellular Endocrinology
- Publisher
- Elsevier BV
- Published
- 2009-05-25
- Volume
- 304
- Issue
- 1-2
- Pages
- 30-42
- ISSN
- 0303-7207 (ISSN-L)
- OpenAlex
- W2103495222
- Cited by
- 351
- References
- 12
- FWCI
- 20.61
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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