Cited by 1,026Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and MetabolismCardiovascular Disease and Adiposity

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Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome

Maury, E., Brichard, S.M.·2010·Molecular and Cellular Endocrinology

DOI 10.1016/j.mce.2009.07.031

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Abstract

Obesity plays a causative role in the pathogenesis of the metabolic syndrome. Adipokines may link obesity to its co-morbidities. Most adipokines with pro-inflammatory properties are overproduced with increasing adiposity, while some adipokines with anti-inflammatory or insulin-sensitizing properties, like adiponectin are decreased. This dysregulation of adipokine production may promote obesity-linked metabolic disorders and cardiovascular disease. Besides considering adipokines, this review will also highlight the cellular key players and molecular mechanisms involved in adipose inflammation. Targeting the changes in the cellular composition of adipose tissue, the underlying molecular mechanisms, and the altered production of adipokines may have therapeutic potential in the management of the metabolic syndrome.

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Hotamisligil, G. S., Shargill, N. S., & Spiegelman, B. M. (1993) · Science · doi:10.1126/science.7678183 · Cited by 7,518
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Xu, H., Barnes, G. T., Yang, Q., Tan, G., Yang, D., Chou, C. J., Sole, J., Nichols, A., Ross, J. S., Tartaglia, L. A., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319451 · Cited by 6,760
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Cani, P. D., Amar, J., Iglesias, M. A., Poggi, M., Knauf, C., Bastelica, D., Neyrinck, A. M., Fava, F., Tuohy, K. M., Chabo, C., et al. (2007) · Diabetes · doi:10.2337/db06-1491 · Cited by 6,638
The gut microbiota as an environmental factor that regulates fat storage
Bäckhed, F., Ding, H., Wang, T., Hooper, L. V., Koh, G. Y., Nagy, A., Semenkovich, C. F., & Gordon, J. I. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407076101 · Cited by 6,245
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Authors: Maury, E., & Brichard, S. M.
Affiliations: UCLouvain (BE)
Corresponding author: Brichard, S.M.
ORCID: Maury, E.
Venue: Molecular and Cellular Endocrinology
Publisher: Elsevier BV
Published: 2010-01-15
Volume: 314
Issue: 1
Pages: 1-16
ISSN: 0303-7207 (ISSN-L)
DOI: 10.1016/j.mce.2009.07.031
OpenAlex: W2094498915
Cited by: 1,026
References: 230
Citations by year: 2026: 20 · 2025: 33 · 2024: 40 · 2023: 38 · 2022: 44 · 2021: 64 · 2020: 69 · 2019: 71 · 2018: 51 · 2017: 61 · 2016: 70 · 2015: 93 · 2014: 73 · 2013: 97 · 2012: 85
FWCI: 44.31
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Molecular and Cellular Endocrinology (publishedVersion)
PubMed (publishedVersion)
Digital Access to Libraries (submittedVersion)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
Health Sciences › Medicine › Physiology (medical) › Adipose Tissue and Metabolism
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
Keywords: adipokines, adipose tissue inflammation, metabolic syndrome, obesity, adiponectin, insulin sensitivity, adipose tissue composition, cardiovascular disease, adipokine dysregulation, therapeutic target
MeSH terms: Apelin, Adipose Tissue, Humans, Inflammation, Insulin, Macrophages, Obesity, Tumor Necrosis Factor-alpha, Signal Transduction, Cytokines, Adipocytes, Chemokines, Metabolic Syndrome, Intercellular Signaling Peptides and Proteins, Body Fat Distribution, Adiponectin, Adipokines, Nicotinamide Phosphoribosyltransferase

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Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome

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