The role of estrogen-metabolizing enzymes and estrogen receptors in human epidermis

Estrogen Receptor Status by Immunohistochemistry Is Superior to the Ligand-Binding Assay for Predicting Response to Adjuvant Endocrine Therapy in Breast Cancer

Harvey, J. M., Clark, G. M., Osborne, C. K., & Allred, D. C. (1999) · Journal of Clinical Oncology · doi:10.1200/jco.1999.17.5.1474 · Cited by 2,054 · see citing works

Aromatase Cytochrome P450, The Enzyme Responsible for Estrogen Biosynthesis*

SIMPSON, E. R., Mahendroo, M., Means, G., Kilgore, M. W., Hinshelwood, M. M., Graham-Lorence, S. E., Amarneh, B., Ito, Y., Fisher, C. R., Michael, M. D., et al. (1994) · Endocrine Reviews · doi:10.1210/edrv-15-3-342 · Cited by 1,534 · see citing works

Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis

Simpson, E. R. (1994) · Endocrine Reviews · doi:10.1210/er.15.3.342 · Cited by 482 · see citing works

Intracrinology: Role of the family of 17 beta-hydroxysteroid dehydrogenases in human physiology and disease

Labrie, F., Luu-The, V, Lin, S., Simard, J., Labrie, C., El-Alfy, M., Pelletier, G., & Belanger, A. (2000) · Journal of Molecular Endocrinology · doi:10.1677/jme.0.0250001 · Cited by 278 · see citing works

Adipose Tissue Intracrinology: Potential Importance of Local Androgen/Estrogen Metabolism in the Regulation of Adiposity

Bélanger, C., Luu-The, V., Dupont, P., & Tchernof, A. (2002) · Hormone and Metabolic Research · doi:10.1055/s-2002-38265 · Cited by 246 · see citing works

Biology of estrogens in skin: implications for skin aging

Verdier‐Sévrain, S., Bonté, F., & Gilchrest, B. A. (2005) · Experimental Dermatology · doi:10.1111/j.1600-0625.2005.00377.x · Cited by 222 · see citing works

Intratumoral Estrogens and Estrogen Receptors in Human Non–Small Cell Lung Carcinoma

Niikawa, H., Suzuki, T., Miki, Y., Suzuki, S., Nagasaki, S., Akahira, J., Honma, S., Evans, D. B., Hayashi, S., Kondo, T., et al. (2008) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-07-1950 · Cited by 195 · see citing works

Gender Differences in Mouse Skin Morphology and Specific Effects of Sex Steroids and Dehydroepiandrosterone

Azzi, L., El-Alfy, M., Martel, C., & Labrie, F. (2005) · Journal of Investigative Dermatology · doi:10.1111/j.0022-202x.2004.23545.x · Cited by 178 · see citing works

Estrogen promotes cutaneous wound healing via estrogen receptor β independent of its antiinflammatory activities

Campbell, L., Emmerson, E., Davies, F., Gilliver, S. C., Krust, A., Chambon, P., Ashcroft, G. S., & Hardman, M. J. (2010) · Journal of Experimental Medicine · doi:10.1084/jem.20100500 · Cited by 175 · see citing works

Systemic Distribution of Steroid Sulfatase and Estrogen Sulfotransferase in Human Adult and Fetal Tissues

Miki, Y., Nakata, T., Suzuki, T., Darnel, A. D., Moriya, T., Kaneko, C., Hidaka, K., Shiotsu, Y., Kusaka, H., & Sasano, H. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-020670 · Cited by 171 · see citing works

Wound Healing and Aging

Goodson, W. H., & Hunt, T. K. (1979) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12532775 · Cited by 140 · see citing works

Aromatase Localization in Human Breast Cancer Tissues: Possible Interactions between Intratumoral Stromal and Parenchymal Cells

Miki, Y., Suzuki, T., Tazawa, C., Yamaguchi, Y., Kitada, K., Honma, S., Moriya, T., Hirakawa, H., Evans, D. B., Hayashi, S., et al. (2007) · Cancer Research · doi:10.1158/0008-5472.can-06-3105 · Cited by 133 · see citing works

Steroid sulfatase of human leukocytes and epidermis and the diagnosis of recessive X-linked ichthyosis.

Epstein, E. H., & LEVENTHAL, M. (1981) · Journal of Clinical Investigation · doi:10.1172/jci110153 · Cited by 113 · see citing works

Intermolecular interactions identify ligand-selective activity of estrogen receptor α/β dimers

Powell, E., & Xu, W. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0807274105 · Cited by 107 · see citing works

Elucidation of estrogen receptor function in bone with the use of mouse models

Windahl, S. H., Andersson, G. N., & Gustafsson, J.-Å. (2002) · Trends in Endocrinology and Metabolism · doi:10.1016/s1043-2760(02)00594-5 · Cited by 102 · see citing works

Intracrinology of estrogens and androgens in breast carcinoma

Sasano, H., Suzuki, T., Miki, Y., & Moriya, T. (2007) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2007.09.012 · Cited by 93 · see citing works

Expression profiles of phases 1 and 2 metabolizing enzymes in human skin and the reconstructed skin models Episkin™ and full thickness model from Episkin™

Luu-The, V., Duché, D., Ferraris, C., et al. (2009) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2009.05.011 · Cited by 92 · see citing works

Increased intratumoral androgens in human breast carcinoma following aromatase inhibitor exemestane treatment

Takagi, K., Miki, Y., Nagasaki, S., Hirakawa, H., Onodera, Y., Akahira, J., Ishida, T., Watanabe, M., Kimijima, I., Hayashi, S., et al. (2010) · Endocrine Related Cancer · doi:10.1677/erc-09-0257 · Cited by 80 · see citing works

Unique multifunctional HSD17B4 gene product: 17beta-hydroxysteroid dehydrogenase 4 and D-3-hydroxyacyl-coenzyme A dehydrogenase/hydratase involved in Zellweger syndrome

de Launoit, Y., & Adamski, J. (1999) · Journal of Molecular Endocrinology · doi:10.1677/jme.0.0220227 · Cited by 79 · see citing works

5α‐Reductase type 1 and aromatase in breast carcinoma as regulators of in situ androgen production

Suzuki, T., Miki, Y., Moriya, T., Akahira, J., Ishida, T., Hirakawa, H., Yamaguchi, Y., Hayashi, S., & Sasano, H. (2006) · International Journal of Cancer · doi:10.1002/ijc.22317 · Cited by 78 · see citing works

Estrogen receptor β expression in human prostate tissue

Pasquali, D., Staibano, S., Prezioso, D., et al. (2001) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(01)00418-x · Cited by 70 · see citing works

Aromatase in bone: roles of Vitamin D3 and androgens

Yanase, T., Suzuki, S., Goto, K., Nomura, M., Okabe, T., Takayanagi, R., & Nawata, H. (2003) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/s0960-0760(03)00349-2 · Cited by 65 · see citing works

Steroid Sulfatase and Estrogen Sulfotransferase in Colon Carcinoma: Regulators of Intratumoral Estrogen Concentrations and Potent Prognostic Factors

Sato, R., Suzuki, T., Katayose, Y., Miura, K., Shiiba, K., Tateno, H., Miki, Y., Akahira, J., Kamogawa, Y., Nagasaki, S., et al. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-0906 · Cited by 60 · see citing works

17β-Hydroxysteroid Dehydrogenase Types 1 and 2 in Human Placenta: An Immunohistochemical Study with Correlation to Placental Development¹

Takeyama, J., Sasano, H., Suzuki, T., Iinuma, K., Nagura, H., & Andersson, S. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.10.5212 · Cited by 54 · see citing works

Differential expression of oestrogen receptor isoforms and androgen receptor in the normal vulva and vagina compared with vulval lichen sclerosus and chronic vaginitis

Taylor, A. H., Guzail, M., & Al‐Azzawi, F. (2007) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2007.08371.x · Cited by 54 · see citing works

Age-related changes in the expression of ER-β mRNA in the female rat brain

Yamaguchi, N., & Yuri, K. (2007) · Brain Research · doi:10.1016/j.brainres.2007.04.016 · Cited by 49 · see citing works

Female sex hormone stimulates cultured human keratinocyte proliferation and its RNA- and protein-synthetic activities

Urano, R., Sakabe, K., Seiki, K., & Ohkido, M. (1995) · Journal of Dermatological Science · doi:10.1016/0923-1811(94)00375-o · Cited by 46 · see citing works

In situ production of sex steroids in human breast carcinoma

Suzuki, T., Miki, Y., Moriya, T., Akahira, J., Hirakawa, H., Ohuchi, N., & Sasano, H. (2007) · Medical Molecular Morphology · doi:10.1007/s00795-007-0365-8 · Cited by 43 · see citing works

Estrogen Receptor β Is a Novel Therapeutic Target for Photoaging

Chang, K. C. N., Wang, Y., Oh, I. G., Jenkins, S. F., Freedman, L. P., Thompson, C. C., Chung, J. H., & Nagpal, S. (2010) · Molecular Pharmacology · doi:10.1124/mol.109.062877 · Cited by 42 · see citing works

Immunocytochemical Studies of Aromatase in Early and Full-Term Human Placental Tissues: Comparison with Biochemical Assays1

Inkster, S. E., & Brodie, A. M. H. (1989) · Biology of Reproduction · doi:10.1095/biolreprod41.5.889 · Cited by 41 · see citing works

Semi-quantitative immunohistochemical analysis of aromatase expression in ductal carcinoma in situ of the breast

Zhang, Z., Yamashita, H., Toyama, T., Hara, Y., Omoto, Y., Sugiura, H., Kobayashi, S., Harada, N., & Iwase, H. (2002) · Breast Cancer Research and Treatment · doi:10.1023/a:1016022314608 · Cited by 40 · see citing works

Expression of 3β-hydroxysteroid dehydrogenase type 1, P450 aromatase, and 17β-hydroxysteroid dehydrogenase types 1, 2, 5 and 7 mRNAs in human early and mid-gestation placentas

Li, Y., ISOMAA, V. V., Pulkka, A. E., Herva, R., Peltoketo, H., & Vihko, P. (2004) · Placenta · doi:10.1016/j.placenta.2004.07.008 · Cited by 34 · see citing works

Steroid metabolism and profile of steroidogenic gene expression in Episkin™: High similarity with human epidermis

Luu-The, V., Ferraris, C., Duché, D., Bélanger, P., Leclaire, J., & Labrie, F. (2007) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2007.03.036 · Cited by 22 · see citing works

Steroidogenic acute regulatory protein: its presence and function in brain neurosteroidogenesis

Kim, H. J., Kang, S. S., Cho, G. J., & Choi, W. S. (2004) · Archivum histologicum japonicum · doi:10.1679/aohc.67.383 · Cited by 16 · see citing works

Skin aging and oxidative stress: Equol’s anti-aging effects via biochemical and molecular mechanisms

Lephart, E. D. (2016) · Ageing Research Reviews · doi:10.1016/j.arr.2016.08.001 · Cited by 325 · see citing works

The role of estrogen in cutaneous ageing and repair

Wilkinson, H. N., & Hardman, M. J. (2017) · Maturitas · doi:10.1016/j.maturitas.2017.06.026 · Cited by 162 · see citing works

The role of estrogen deficiency in skin ageing and wound healing

Emmerson, E., & Hardman, M. J. (2012) · Biogerontology · doi:10.1007/s10522-011-9322-y · Cited by 118 · see citing works

A review of the role of estrogen in dermal aging and facial attractiveness in women

Lephart, E. D. (2018) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.12508 · Cited by 114 · see citing works

Platelets induce increased estrogen production through NF-κB and TGF-β1 signaling pathways in endometriotic stromal cells

Qi, Q., Liu, X., Zhang, Q., & Guo, S.-W. (2020) · Scientific Reports · doi:10.1038/s41598-020-57997-6 · Cited by 44 · see citing works

Dual Aromatase−Steroid Sulfatase Inhibitors

Woo, L. W. L., Bubert, C., Sutcliffe, O. B., Smith, A., Chander, S. K., Mahon, M. F., Purohit, A., Reed, M. J., & Potter, B. V. L. (2007) · Journal of Medicinal Chemistry · doi:10.1021/jm061462b · Cited by 80 · see citing works

First Dual Aromatase-Steroid Sulfatase Inhibitors

Woo, L. W. L., Sutcliffe, O. B., Bubert, C., Grasso, A., Chander, S. K., Purohit, A., Reed, M. J., & Potter, B. V. L. (2003) · Journal of Medicinal Chemistry · doi:10.1021/jm034033b · Cited by 69 · see citing works

Hybrid Dual Aromatase-Steroid Sulfatase Inhibitors with Exquisite Picomolar Inhibitory Activity

Woo, L. W. L., Bubert, C., Purohit, A., et al. (2010) · ACS Medicinal Chemistry Letters · doi:10.1021/ml100273k · Cited by 38 · see citing works

Aromatase and steroid sulfatase mRNA expression in fine needle aspirates from benign and malignant breast disorders

Gao, Lei, L., Qi, et al. (2012) · 中国科学通报：英文版

Aromatase and Dual Aromatase‐Steroid Sulfatase Inhibitors from the Letrozole and Vorozole Templates

Wood, P. M., Woo, L. W. L., THOMAS, M. P., Mahon, M. F., Purohit, A., & Potter, B. V. L. (2011) · ChemMedChem · doi:10.1002/cmdc.201100145 · Cited by 64 · see citing works