Cited by 149Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental DisordersRNA Research and Splicing

The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.

Differential expression and dendritic transcript localization of Shank family members: identification of a dendritic targeting element in the 3′ untranslated region of Shank1 mRNA

Böckers, Tobias M., Segger-Junius, Mailin, Iglauer, Peter, Bockmann, Jürgen, Gundelfinger, Eckart D., Kreutz, Michael R., Richter, Dietmar, Kindler, Stefan, Kreienkamp, Hans-Jürgen·2004·Molecular and Cellular Neuroscience

DOI 10.1016/j.mcn.2004.01.009

Open this paper in CoChat — free account

Abstract

Shank proteins are scaffolding proteins in the postsynaptic density of excitatory synapses in the mammalian brain. In situ hybridization revealed that Shank1/SSTRIP and Shank2/ProSAP1 mRNAs are widely expressed early in postnatal brain development whereas Shank3/ProSAP2 expression increases during postnatal development especially in the cerebellum and thalamus. Shank1 and Shank3 (but not Shank2) mRNAs are present in the molecular layers of the hippocampus, consistent with a dendritic transcript localization. Shank1 and Shank2 transcripts are detectable in the dendritic fields of Purkinje cells, whereas Shank3 mRNA is restricted to cerebellar granule cells. The appearance of dendritic Shank mRNAs in cerebellar Purkinje cells coincides with the onset of dendrite formation. Expression of reporter transcripts in hippocampal neurons identifies a 200-nucleotide dendritic targeting element (DTE) in the Shank1 mRNA. The widespread presence of Shank mRNAs in dendrites suggests a role for local synthesis of Shanks in response to stimuli that induce alterations in synaptic morphology.

Integrity signals

Registry

Crossref · 10.1016/j.mcn.2004.01.009

Cites

38 of 38 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Culturing nerve cells
Banker, G. A., & Goslin, K. (1998) · Cited by 1,290
Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites
Lyford, G. L., Yamagata, K., Kaufmann, W. E., Barnes, C. A., Sanders, L. K., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Lanahan, A. A., & Worley, P. F. (1995) · Neuron · doi:10.1016/0896-6273(95)90299-6 · Cited by 1,212
Coupling of mGluR/Homer and PSD-95 Complexes by the Shank Family of Postsynaptic Density Proteins
Tu, J. C., Xiao, B., Naisbitt, S. R., Yuan, J. P., Petralia, R. S., Brakeman, P., Doan, A., Aakalu, V. K., Lanahan, A. A., Sheng, M., et al. (1999) · Neuron · doi:10.1016/s0896-6273(00)80810-7 · Cited by 1,079
Shank, a Novel Family of Postsynaptic Density Proteins that Binds to the NMDA Receptor/PSD-95/GKAP Complex and Cortactin
Naisbitt, S., Kim, E., Tu, J. C., Xiao, B., Sala, C., Valtschanoff, J., Weinberg, R. J., Worley, P. F., & Sheng, M. (1999) · Neuron · doi:10.1016/s0896-6273(00)80809-0 · Cited by 1,009
A Requirement for Local Protein Synthesis in Neurotrophin-Induced Hippocampal Synaptic Plasticity
Kang, H., & Schuman, E. M. (1996) · Science · doi:10.1126/science.273.5280.1402 · Cited by 996
Regulation of Dendritic Spine Morphology and Synaptic Function by Shank and Homer
Sala, C., Piëch, V., Wilson, N. R., Passafaro, M., Liu, G., & Sheng, M. (2001) · Neuron · doi:10.1016/s0896-6273(01)00339-7 · Cited by 716
Somatodendritic expression of an immediate early gene is regulated by synaptic activity.
Link, W., Konietzko, U., Kauselmann, G., Krug, M., Schwanke, B., Frey, U., & Kuhl, D. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.12.5734 · Cited by 710
Preferential localization of polyribosomes under the base of dendritic spines in granule cells of the dentate gyrus
Steward, O., & Levy, W. (1982) · The Journal of Neuroscience · doi:10.1523/jneurosci.02-03-00284.1982 · Cited by 676
Cloning of a novel glutamate receptor subunit, GluR5: Expression in the nervous system during development
Bettler, B., Boulter, J., Hermans-Borgmeyer, I., O'Shea-Greenfield, A., Deneris, E. S., Moll, C., Borgmeyer, U., Hollmann, M., & Heinemann, S. (1990) · Neuron · doi:10.1016/0896-6273(90)90213-y · Cited by 649
In situ hybridization histochemistry of Ca2+/calmodulin-dependent protein kinase in developing rat brain
Burgin, K., Waxham, M., Rickling, S., Westgate, S., Mobley, W. C., & Kelly, P. (1990) · Journal of Neuroscience · doi:10.1523/jneurosci.10-06-01788.1990 · Cited by 564

Show all 38 references

Sorted by citations

The neuronal microRNA system
Kosik, K. S. (2006) · Nature reviews. Neuroscience · doi:10.1038/nrn2037 · Cited by 834
The local transcriptome in the synaptic neuropil revealed by deep sequencing and high-resolution imaging
Cajigas, I. J., Tushev, G., Will, T. J., tom Dieck, S., Fuerst, N., & Schuman, E. M. (2012) · Neuron · doi:10.1016/j.neuron.2012.02.036 · Cited by 709
Cell-free Formation of RNA Granules: Bound RNAs Identify Features and Components of Cellular Assemblies
Han, T. W., Kato, M., Xie, S., Wu, L. C., Mirzaei, H., Pei, J., Chen, M., Xie, Y., Allen, J. D., Xiao, G., et al. (2012) · Cell · doi:10.1016/j.cell.2012.04.016 · Cited by 773
BDNF-induced local protein synthesis and synaptic plasticity
Leal, G., Comprido, D., & Duarte, C. B. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.04.005 · Cited by 705
SHANK proteins: roles at the synapse and in autism spectrum disorder
Monteiro, P., & Feng, G. (2017) · Nature Reviews Neuroscience · doi:10.1038/nrn.2016.183 · Cited by 681
The Central Dogma Decentralized: New Perspectives on RNA Function and Local Translation in Neurons
Holt, C. E., & Schuman, E. M. (2013) · Neuron · doi:10.1016/j.neuron.2013.10.036 · Cited by 525
Modeling Autism by SHANK Gene Mutations in Mice
Jiang, Y.-H., & Ehlers, M. D. (2013) · Neuron · doi:10.1016/j.neuron.2013.03.016 · Cited by 488
MECHANISMS OF VERTEBRATE SYNAPTOGENESIS
Waites, C. L., Craig, A. M., & Garner, C. C. (2005) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.27.070203.144336 · Cited by 483
The 22q13.3 Deletion Syndrome (Phelan-McDermid Syndrome)
Phelan, K., & McDermid, H. E. (2011) · Molecular Syndromology · doi:10.1159/000334260 · Cited by 460
Smaller Dendritic Spines, Weaker Synaptic Transmission, but Enhanced Spatial Learning in Mice Lacking Shank1
Hung, A. Y., Futai, K., Sala, C., Valtschanoff, J. G., Ryu, J., Woodworth, M. A., Kidd, F. L., Sung, C. C., Miyakawa, T., Bear, M. F., et al. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.3032-07.2008 · Cited by 350
To localize or not to localize: mRNA fate is in 3′UTR ends
Andreassi, C., & Riccio, A. (2009) · Trends in Cell Biology · doi:10.1016/j.tcb.2009.06.001 · Cited by 351
Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects
Zhou, Y., Kaiser, T., Monteiro, P., Zhang, X., Van der Goes, M. S., Wang, D., Barak, B., Zeng, M., Li, C., Lu, C., et al. (2016) · Neuron · doi:10.1016/j.neuron.2015.11.023 · Cited by 325
Shank Expression Is Sufficient to Induce Functional Dendritic Spine Synapses in Aspiny Neurons
Roussignol, G., Ango, F., Romorini, S., Tu, J. C., Sala, C., Worley, P. F., Bockaert, J., & Fagni, L. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.4354-04.2005 · Cited by 293
Reduction in parvalbumin expression not loss of the parvalbumin-expressing GABA interneuron subpopulation in genetic parvalbumin and shank mouse models of autism
Filice, F., Vörckel, K. J., Sungur, A. Ö., Wöhr, M., & Schwaller, B. (2016) · Molecular Brain · doi:10.1186/s13041-016-0192-8 · Cited by 240
The emerging role of SHANK genes in neuropsychiatric disorders
Guilmatre, A., Huguet, G., Delorme, R., & Bourgeron, T. (2014) · Developmental Neurobiology · doi:10.1002/dneu.22128 · Cited by 237
Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies
Grabrucker, A. M., Schmeisser, M. J., Schoen, M., & Boeckers, T. M. (2011) · Trends in Cell Biology · doi:10.1016/j.tcb.2011.07.003 · Cited by 233
Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice
Peter, S., ten Brinke, M. M., Stedehouder, J., Reinelt, C. M., Wu, B., Zhou, H., Zhou, K., Boele, H., Kushner, S. A., Lee, M. G., et al. (2016) · Nature Communications · doi:10.1038/ncomms12627 · Cited by 225
Sociability and motor functions in Shank1 mutant mice
Silverman, J. L., Turner, S. M., Barkan, C. L., Tolu, S. S., Saxena, R., Hung, A. Y., Sheng, M., & Crawley, J. N. (2011) · Brain Research · doi:10.1016/j.brainres.2010.09.026 · Cited by 218
Communication impairments in mice lacking Shank1: reduced levels of ultrasonic vocalizations and scent marking behavior
Wöhr, M., Roullet, F. I., Hung, A. Y., Sheng, M., & Crawley, J. N. (2011) · PLoS ONE · doi:10.1371/journal.pone.0020631 · Cited by 220
RNA TRANSPORT AND LOCAL CONTROL OF TRANSLATION
Kindler, S., Wang, H., Richter, D., & Tiedge, H. (2005) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.21.122303.120653 · Cited by 215
Self-citation
Local Protein Synthesis and Spine Morphogenesis: Fragile X Syndrome and Beyond
Grossman, A. W., Aldridge, G. M., Weiler, I. J., & Greenough, W. T. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.1790-06.2006 · Cited by 177
SHANK3 as an autism spectrum disorder-associated gene
Uchino, S., & Waga, C. (2013) · Brain and Development · doi:10.1016/j.braindev.2012.05.013 · Cited by 176
Shank synaptic scaffold proteins: keys to understanding the pathogenesis of autism and other synaptic disorders
Sala, C., Vicidomini, C., Bigi, I., Mossa, A., & Verpelli, C. (2015) · Journal of Neurochemistry · doi:10.1111/jnc.13232 · Cited by 182
Local Sharing as a Predominant Determinant of Synaptic Matrix Molecular Dynamics
Tsuriel, S., Geva, R., Zamorano, P. L., Dresbach, T., Boeckers, T. M., Gundelfinger, E. D., Garner, C. C., & Ziv, N. E. (2006) · PLoS Biology · doi:10.1371/journal.pbio.0040271 · Cited by 164
Self-citation
Fragile X Mental Retardation Protein Regulates the Levels of Scaffold Proteins and Glutamate Receptors in Postsynaptic Densities
Schütt, J., Falley, K., Richter, D., Kreienkamp, H., & Kindler, S. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.042663 · Cited by 158
Self-citation
Cerebellar associative sensory learning defects in five mouse autism models
Kloth, A. D., Badura, A., Li, A., Cherskov, A., Connolly, S. G., Giovannucci, A., Bangash, M. A., Grasselli, G., Peñagarikano, O., Piochon, C., et al. (2015) · eLife · doi:10.7554/elife.06085 · Cited by 148
Uncovering Molecular Biomarkers That Correlate Cognitive Decline with the Changes of Hippocampus' Gene Expression Profiles in Alzheimer's Disease
Ravetti, M. G., Rosso, O. A., Berretta, R. E., & Moscato, P. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010153 · Cited by 144
Developmental vulnerability of synapses and circuits associated with neuropsychiatric disorders
Penzes, P., Buonanno, A., Passafaro, M., Sala, C., & Sweet, R. A. (2013) · Journal of Neurochemistry · doi:10.1111/jnc.12261 · Cited by 125
Phelan–McDermid Syndrome and SHANK3: Implications for Treatment
Costales, J. L., & Kolevzon, A. (2015) · Neurotherapeutics · doi:10.1007/s13311-015-0352-z · Cited by 130
Cerebellar Shank2 Regulates Excitatory Synapse Density, Motor Coordination, and Specific Repetitive and Anxiety-Like Behaviors
Ha, S., Lee, D., Cho, Y. S., Chung, C., Yoo, Y.-E., Kim, J., Lee, J., Kim, W., Kim, H., Bae, Y. C., et al. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.1849-16.2016 · Cited by 110
Functional Consequences of Mutations in Postsynaptic Scaffolding Proteins and Relevance to Psychiatric Disorders
Ting, J. T., Peça, J., & Feng, G. (2012) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-062111-150442 · Cited by 110
Degradation of Postsynaptic Scaffold GKAP and Regulation of Dendritic Spine Morphology by the TRIM3 Ubiquitin Ligase in Rat Hippocampal Neurons
Hung, A. Y., Sung, C. C., Brito, I. L., & Sheng, M. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009842 · Cited by 106
Scaffolding proteins at the postsynaptic density: shank as the architectural framework
Kreienkamp, H. J. (2008) · Handbook of experimental pharmacology · doi:10.1007/978-3-540-72843-6_15 · Cited by 105
Self-citation
The Cerebellar Involvement in Autism Spectrum Disorders: From the Social Brain to Mouse Models
Mapelli, L., Soda, T., D'Angelo, E. U., & Prestori, F. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23073894 · Cited by 114
A role for zinc in postsynaptic density asSAMbly and plasticity?
Gundelfinger, E. D., Boeckers, T. M., Baron, M. K., & Bowie, J. U. (2006) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2006.05.007 · Cited by 98
Self-citation
Cellular and synaptic network defects in autism
Peça, J., & Feng, G. (2012) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2012.02.015 · Cited by 96
Direct interaction of post‐synaptic density‐95/Dlg/ZO‐1 domain‐containing synaptic molecule Shank3 with GluR1 α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazole propionic acid receptor
Uchino, S., Wada, H., Honda, S., Nakamura, Y., Ondo, Y., Uchiyama, T., Tsutsumi, M., Suzuki, E., Hirasawa, T., & Kohsaka, S. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.03831.x · Cited by 95
Postsynaptic Shank Antagonizes Dendrite Branching Induced by the Leucine-Rich Repeat Protein Densin-180
Quitsch, A., Berhörster, K., Liew, C. W., Richter, D., & Kreienkamp, H.-J. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.2699-04.2005 · Cited by 95
Self-citation
Comparison of SHANK3 deficiency in animal models: phenotypes, treatment strategies, and translational implications
Delling, J. P., & Boeckers, T. M. (2021) · Journal of Neurodevelopmental Disorders · doi:10.1186/s11689-021-09397-8 · Cited by 104
Scaffold Proteins at the Postsynaptic Density
Verpelli, C., Schmeisser, M. J., Sala, C., & Boeckers, T. M. (2012) · Advances in Experimental Medicine and Biology · doi:10.1007/978-3-7091-0932-8_2 · Cited by 92
Isoform cell-type specificity in the mouse primary motor cortex
Booeshaghi, A. S., Yao, Z., van Velthoven, C. T. J., Smith, K. A., Tasic, B., Zeng, H., & Pachter, L. S. (2021) · Nature · doi:10.1038/s41586-021-03969-3 · Cited by 81
Think locally: control of ubiquitin‐dependent protein degradation in neurons
Segref, A., & Hoppe, T. (2008) · EMBO Reports · doi:10.1038/embor.2008.229 · Cited by 72
Identification of 22q13 genes most likely to contribute to Phelan McDermid syndrome
Mitz, A. R., Philyaw, T. J., Boccuto, L., Shcheglovitov, A., Sarasua, S. M., Kaufmann, W. E., & Thurm, A. E. (2018) · European Journal of Human Genetics · doi:10.1038/s41431-017-0042-x · Cited by 72
Deficiency of Shank2 causes mania-like behavior that responds to mood stabilizers
Pappas, A. L., Bey, A. L., Wang, X., Rossi, M. A., Kim, Y. H., Yan, H., Porkka, F., Duffney, L. J., Phillips, S. M., Cao, X., et al. (2017) · JCI Insight · doi:10.1172/jci.insight.92052 · Cited by 76
The PSD protein ProSAP2/Shank3 displays synapto-nuclear shuttling which is deregulated in a schizophrenia-associated mutation
Grabrucker, S., Proepper, C., Mangus, K., Eckert, M., Chhabra, R., Schmeißer, M. J., Boeckers, T. M., & Grabrucker, A. M. (2014) · Experimental Neurology · doi:10.1016/j.expneurol.2013.12.015 · Cited by 66
Asymmetric mRNA localization contributes to fidelity and sensitivity of spatially localized systems
Weatheritt, R. J., Gibson, T. J., & Babu, M. M. (2014) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2876 · Cited by 61
Distinct Phenotypes of Shank2 Mouse Models Reflect Neuropsychiatric Spectrum Disorders of Human Patients With SHANK2 Variants
Eltokhi, A., Rappold, G., & Sprengel, R. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00240 · Cited by 63
FMRP interacts with G-quadruplex structures in the 3’-UTR of its dendritic target Shank1 mRNA
Zhang, Y., Gaetano, C. M., Williams, K. R., Bassell, G. J., & Mihailescu, M. (2014) · RNA Biology · doi:10.1080/15476286.2014.996464 · Cited by 59
Zinc Stabilizes Shank3 at the Postsynaptic Density of Hippocampal Synapses
Tao-Cheng, J.-H., Toy, D., Winters, C. A., Reese, T. S., & Döṣemeci, A. (2016) · PLoS ONE · doi:10.1371/journal.pone.0153979 · Cited by 59
Distinct spatiotemporal expression of SAPAP transcripts in the developing rat brain: a novel dendritically localized mRNA
Kindler, S., Rehbein, M., Classen, B., Richter, D., & Böckers, T. M. (2004) · Molecular Brain Research · doi:10.1016/j.molbrainres.2004.03.014 · Cited by 56
Self-citation
Digital expression profiling of the compartmentalized translatome of Purkinje neuronsPreprint
Kratz, A., Béguin, P., Kaneko, M., Chimura, T., Suzuki, A. M., Matsunaga, A., Kato, S., Bertin, N., Lassmann, T., Vigot, R., et al. (2014) · Genome Research · doi:10.1101/gr.164095.113 · Cited by 55
Dendritic mRNA Targeting and Translation
Kindler, S., & Kreienkamp, H. (2012) · Advances in experimental medicine and biology · doi:10.1007/978-3-7091-0932-8_13 · Cited by 54
Self-citation
RNA‐binding proteins involved in RNA localization and their implications in neuronal diseases
Tolino, M., Köhrmann, M., & Kiebler, M. A. (2012) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2012.08160.x · Cited by 51
Contributions of T-Type Voltage-Gated Calcium Channels to Postsynaptic Calcium Signaling within Purkinje Neurons
Isope, P., Hildebrand, M. E., & Snutch, T. P. (2010) · The Cerebellum · doi:10.1007/s12311-010-0195-4 · Cited by 58
Postsynaptic recruitment of Dendrin depends on both dendritic mRNA transport and synaptic anchoring
Kremerskothen, J., Kindler, S., Finger, I., Veltel, S., & Barnekow, A. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.03679.x · Cited by 47
Self-citation
Dendritic protein synthesis in the normal and diseased brain
Swanger, S. A., & Bassell, G. J. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.12.003 · Cited by 51
Shank1 mRNA: Dendritic Transport by Kinesin and Translational Control by the 5′Untranslated Region
Falley, K., Schütt, J., Iglauer, P., Menke, K., Maas, C., Kneussel, M., Kindler, S., Wouters, F. S., Richter, D., & Kreienkamp, H. (2009) · Traffic · doi:10.1111/j.1600-0854.2009.00912.x · Cited by 45
Self-citation
Hippocampus-Dependent Goal Localization by Head-Fixed Mice in Virtual Reality
Sato, M., Kawano, M., Mizuta, K., Islam, T., Lee, M. G., & Hayashi, Y. (2017) · eNeuro · doi:10.1523/eneuro.0369-16.2017 · Cited by 46
Dysregulation of protein synthesis and dendritic spine morphogenesis in ASD: studies in human pluripotent stem cells
Lo, L. H.-Y., & Lai, K. (2020) · Molecular Autism · doi:10.1186/s13229-020-00349-y · Cited by 47
Schizophrenia in a patient with subtelomeric duplication of chromosome 22q
Failla, P., Romano, C., Alberti, A., Vasta, A., Buono, S., Castiglia, L., Luciano, D., Benedetto, D. D., Fichera, M., & Galesi, O. (2007) · Clinical Genetics · doi:10.1111/j.1399-0004.2007.00819.x · Cited by 40
Shankopathies in the Developing Brain in Autism Spectrum Disorders
Vyas, Y., Cheyne, J. E., Lee, K., Jung, Y., Cheung, P. Y., & Montgomery, J. M. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.775431 · Cited by 46
The Role of Zinc and NMDA Receptors in Autism Spectrum Disorders
Lee, K. C., Mills, Z., Cheung, P. Y., Cheyne, J. E., & Montgomery, J. M. (2022) · Pharmaceuticals · doi:10.3390/ph16010001 · Cited by 42
SHANK genes in autism: Defining therapeutic targets
Mossa, A., Giona, F., Pagano, J., Sala, C., & Verpelli, C. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.11.019 · Cited by 40
Imbalanced post- and extrasynaptic SHANK2A functions during development affect social behavior in SHANK2-mediated neuropsychiatric disorders
Eltokhi, A., Gonzalez-Lozano, M. A., Oettl, L.-L., Rozov, A., Pitzer, C., Röth, R., Berkel, S., Hüser, M., Harten, A., Kelsch, W., et al. (2021) · Molecular Psychiatry · doi:10.1038/s41380-021-01140-y · Cited by 38
Expression of the Excitatory Postsynaptic Scaffolding Protein, Shank3, in Human Brain: Effect of Age and Alzheimer’s Disease
Wan, L., Ai, J.-Q., Yang, C. G., Jiang, J., Zhang, Q., Luo, Z., Huang, R., Tu, T., Pan, A., Tu, E., et al. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.717263 · Cited by 37
Post-transcriptional Processing of mRNA in Neurons: The Vestiges of the RNA World Drive Transcriptome Diversity
Andreassi, C., Crerar, H., & Riccio, A. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00304 · Cited by 32
A Comparative Perspective on Wnt/β-Catenin Signalling in Cell Fate Determination
Garcin, C. L., & Habib, S. J. (2017) · Results and problems in cell differentiation · doi:10.1007/978-3-319-53150-2_15 · Cited by 40
Deletion of the Autism-Associated Protein SHANK3 Abolishes Structural Synaptic Plasticity after Brain Trauma
Urrutia‐Ruiz, C., Rombach, D., Cursano, S., Gerlach-Arbeiter, S., Schoen, M., Bockmann, J., Demestre, M., & Boeckers, T. M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23116081 · Cited by 36
Self-citation
MicroRNA-7/Shank3 axis involved in schizophrenia pathogenesis
Zhang, J., Sun, X., & Zhang, L.-Y. (2015) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2015.01.031 · Cited by 36
A recurrent SHANK1 mutation implicated in autism spectrum disorder causes autistic-like core behaviors in mice via downregulation of mGluR1-IP3R1-calcium signaling
Qin, Y., Du, Y., Chen, L., Liu, Y., Xu, W., Liu, Y., Li, Y., Leng, J., Wang, Y., Zhang, X., et al. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01539-1 · Cited by 35
Proteostasis and RNA Binding Proteins in Synaptic Plasticity and in the Pathogenesis of Neuropsychiatric Disorders
Klein, M. E., Monday, H. R., & Jordan, B. A. (2016) · Neural Plasticity · doi:10.1155/2016/3857934 · Cited by 37
Shank3‐deficient thalamocortical neurons show HCN channelopathy and alterations in intrinsic electrical properties
Zhu, M., Idikuda, V. K., Wang, J., Wei, F., Kumar, V., Shah, N., Waite, C. B., Liu, Q., & Zhou, L. (2018) · The Journal of Physiology · doi:10.1113/jp275147 · Cited by 35
Interaction of neurodevelopmental pathways and synaptic plasticity in mental retardation, autism spectrum disorder and schizophrenia: Implications for psychiatry
Waltereit, R., Banaschewski, T., Meyer‐Lindenberg, A., & Poustka, L. (2013) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2013.838641 · Cited by 34
Hyperactivity and Hypermotivation Associated With Increased Striatal mGluR1 Signaling in a Shank2 Rat Model of Autism
Modi, M. E., Brooks, J. M., Guilmette, E. R., Beyna, M., Graf, R., Reim, D., Schmeißer, M. J., Boeckers, T. M., O’Donnell, P., & Buhl, D. L. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00107 · Cited by 36
Prenylation of Axonally Translated Rac1 Controls NGF-Dependent Axon Growth
Scott-Solomon, E., & Kuruvilla, R. (2020) · Developmental Cell · doi:10.1016/j.devcel.2020.05.020 · Cited by 33
Dosage-sensitive genes in autism spectrum disorders: From neurobiology to therapy
Javed, S., Selliah, T., Lee, Y., & Huang, W. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.08.009 · Cited by 32
Ultrastructural analyses in the hippocampus CA1 field in Shank3-deficient mice
Uppal, N., Puri, R., Yuk, F., Janssen, W. G. M., Bozdagi-Gunal, O., Harony‐Nicolas, H., Dickstein, D. L., Buxbaum, J. D., & Hof, P. R. (2015) · Molecular Autism · doi:10.1186/s13229-015-0036-x · Cited by 33
Molecular architecture of postsynaptic Interactomes
Wilkinson, B., & Coba, M. P. (2020) · Cellular Signalling · doi:10.1016/j.cellsig.2020.109782 · Cited by 25
Aberrant cognitive phenotypes and altered hippocampal BDNF expression related to epigenetic modifications in mice lacking the post‐synaptic scaffolding protein SHANK1: Implications for autism spectrum disorder
Sungur, A. Ö., Jochner, M. C. E., Harb, H., Kılıç, A., Garn, H., Schwarting, R. K. W., & Wöhr, M. (2017) · Hippocampus · doi:10.1002/hipo.22741 · Cited by 30
Selective distribution and dynamic modulation of miRNAs in the synapse and its possible role in Alzheimer's Disease
Garza-Manero, S., Pichardo‐Casas, I., Arias, C., Vaca, L. A., & Zepeda, A. (2013) · Brain Research · doi:10.1016/j.brainres.2013.12.009 · Cited by 28
A Non-Canonical Initiation Site Is Required for Efficient Translation of the Dendritically Localized Shank1 mRNA
Studtmann, K., Ölschläger‐Schütt, J., Buck, F., Richter, D., Sala, C., Bockmann, J., Kindler, S., & Kreienkamp, H. (2014) · PLoS ONE · doi:10.1371/journal.pone.0088518 · Cited by 26
Self-citation
Dendritic mRNA Targeting of Jacob and N-Methyl-d-aspartate-induced Nuclear Translocation after Calpain-mediated Proteolysis
Kindler, S., Dieterich, D. C., Schütt, J., Sahin, J., Karpova, A., Mikhaylova, M., Schob, C., Gundelfinger, E. D., Kreienkamp, H., & Kreutz, M. R. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.022137 · Cited by 26
Self-citation
Identification of two novel Shank3 transcripts in the developing mouse neocortex
Waga, C., Asano, H., Sanagi, T., Suzuki, E., Nakamura, Y., Tsuchiya, A., Itoh, M., Goto, Y., Kohsaka, S., & Uchino, S. (2013) · Journal of Neurochemistry · doi:10.1111/jnc.12505 · Cited by 25
Alternative polyadenylation and differential expression of Shank mRNAs in the synaptic neuropil
Epstein, I., Tushev, G., Will, T. J., Vlatkovic, I., Cajigas, I. J., & Schuman, E. M. (2013) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2013.0137 · Cited by 24
Behavioral phenotypes and neurobiological mechanisms in the Shank1 mouse model for autism spectrum disorder: A translational perspective
Sungur, A. Ö., Schwarting, R. K. W., & Wöhr, M. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.09.038 · Cited by 24
Volumetric Analysis of the Basal Ganglia and Cerebellar Structures in Patients with Phelan-McDermid Syndrome
Srivastava, S., Scherrer, B., Prohl, A. K., Filip-Dhima, R., Kapur, K., Kolevzon, A., Buxbaum, J. D., Berry-Kravis, E., Soorya, L., Thurm, A., et al. (2019) · Pediatric Neurology · doi:10.1016/j.pediatrneurol.2018.09.008 · Cited by 23
Novel Therapeutic Approach for Autism Spectrum Disorder: Focus on SHANK3
Uchino, S., & Waga, C. (2015) · Current Neuropharmacology · doi:10.2174/1570159x13666151029105547 · Cited by 27
Mutations of the synapse genes and intellectual disability syndromes
Verpelli, C., Montani, C., Vicidomini, C., Heise, C., & Sala, C. (2013) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2013.07.023 · Cited by 27
Bridging the translational gap: what can synaptopathies tell us about autism?
Molloy, C. J., Cooke, J., Gatford, N. J. F., Rivera-Olvera, A., Avazzadeh, S., Homberg, J. R., Grandjean, J., Fernandes, C., Shen, S., Loth, E., et al. (2023) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2023.1191323 · Cited by 23
Therapeutic approaches for shankopathies
Wang, X., Bey, A. L., Chung, L., Krystal, A. D., & Jiang, Y. (2013) · Developmental Neurobiology · doi:10.1002/dneu.22084 · Cited by 23
3'-UTR SIRF: A database for identifying clusters of short interspersed repeats in 3' untranslated regions
Andken, B. B., Lim, I. Y., Benson, G., Vincent, J. J., Ferenc, M. T., Heinrich, B. S., Jarzylo, L. A., Man, H., & Deshler, J. O. (2007) · BMC Bioinformatics · doi:10.1186/1471-2105-8-274 · Cited by 22
Defective Synapse Maturation and Enhanced Synaptic Plasticity in Shank2 Δex7 –/– Mice
Wegener, S., Buschler, A., Stempel, A. V., Kang, S. J., Lim, C., Kaang, B., Shoichet, S. A., Manahan‐Vaughan, D., & Schmitz, D. (2018) · eNeuro · doi:10.1523/eneuro.0398-17.2018 · Cited by 25
Translating preclinical findings in clinically relevant new antipsychotic targets: focus on the glutamatergic postsynaptic density. Implications for treatment resistant schizophrenia
de Bartolomeis, A., Avagliano, C., Vellucci, L., D’Ambrosio, L., Manchia, M., D’Urso, G., Buonaguro, E. F., & Iasevoli, F. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.08.019 · Cited by 19
Deletion of Shank1 has minimal effects on the molecular composition and function of glutamatergic afferent postsynapses in the mouse inner ear
Braude, J. P., Vijayakumar, S., Baumgarner, K. M., Laurine, R., Jones, T. A., Jones, S. M., & Pyott, S. J. (2015) · Hearing Research · doi:10.1016/j.heares.2015.01.008 · Cited by 23
SHANK family on stem cell fate and development
Liu, X., Yuan, M., Lau, B. W.-M., & Li, Y. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-05325-3 · Cited by 21
Loose ligation of the rat sciatic nerve elicits early accumulation of Shank1 protein in the post-synaptic density of spinal dorsal horn neurons
Miletić, G., Dumitrascu, C. I., Honstad, C. E., Micic, D., & Miletić, V. (2010) · Pain · doi:10.1016/j.pain.2010.02.001 · Cited by 19
Autism Spectrum Disorder Genes: Disease-Related Networks and Compensatory Strategies
Lim, H. K., Yoon, J. H., & Song, M. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.922840 · Cited by 18
Remote ischemic conditioning alleviates chronic cerebral hypoperfusion-induced cognitive decline and synaptic dysfunction via the miR-218a-5p/SHANK2 pathway
Li, N., Ren, C., Li, S., Yu, W., Jin, K., & Ji, X. (2023) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2023.102514 · Cited by 17
Abnormalities in synaptic dynamics during development in a mouse model of spinocerebellar ataxia type 1
Hatanaka, Y., Watase, K., Wada, K., & Nagai, Y. (2015) · Scientific Reports · doi:10.1038/srep16102 · Cited by 18
Adenosine A1 Receptor mRNA Expression by Neurons and Glia in the Auditory Forebrain
Hackett, T. A. (2018) · The Anatomical Record · doi:10.1002/ar.23907 · Cited by 17

Authors: Böckers, T. M., Segger-Junius, M., Iglauer, P., Bockmann, J., Gundelfinger, E. D., Kreutz, M. R., Richter, D., Kindler, S., & Kreienkamp, H.-J.
Affiliations: Universität Ulm (DE)
Universität Hamburg (DE)
Leibniz Institute for Neurobiology (DE)
Corresponding author: Kreienkamp, Hans-Jürgen
ORCID: Gundelfinger, Eckart D.
Kreutz, Michael R.
Kindler, Stefan
Kreienkamp, Hans-Jürgen
Venue: Molecular and Cellular Neuroscience
Publisher: Elsevier BV
Published: 2004-05
Volume: 26
Issue: 1
Pages: 182-190
ISSN: 1044-7431 (ISSN-L)
DOI: 10.1016/j.mcn.2004.01.009
OpenAlex: W1994881764
Cited by: 149
References: 38
Citations by year: 2025: 5 · 2024: 14 · 2023: 7 · 2022: 6 · 2021: 6 · 2020: 5 · 2019: 3 · 2018: 10 · 2017: 9 · 2016: 6 · 2015: 10 · 2014: 7 · 2013: 13 · 2012: 11
FWCI: 1.99
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Molecular and Cellular Neuroscience (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Research and Splicing
Keywords: Shank1, Shank2, SHANK3, dendritic mRNA localization, 3' untranslated region, postsynaptic density, excitatory synapses, postnatal brain development, cerebellum, hippocampus, Purkinje cells, cerebellar granule cells, dendrite formation, local protein synthesis, synaptic plasticity
MeSH terms: Animals, Brain, Carrier Proteins, Cerebellar Cortex, Dendrites, Genes, Regulator, Hippocampus, Nerve Tissue Proteins, Synaptic Transmission, RNA, Messenger, Synaptic Membranes, Genes, Reporter, Gene Expression Regulation, Developmental, 3' Untranslated Regions, Protein Transport, Adaptor Proteins, Signal Transducing, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Differential expression and dendritic transcript localization of Shank family members: identification of a dendritic targeting element in the 3′ untranslated region of Shank1 mRNA

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks