The emerging role of SHANK genes in neuropsychiatric disorders

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Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3

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Genetic and Functional Analyses of SHANK2 Mutations Suggest a Multiple Hit Model of Autism Spectrum Disorders

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Smaller Dendritic Spines, Weaker Synaptic Transmission, but Enhanced Spatial Learning in Mice Lacking Shank1

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Key role for gene dosage and synaptic homeostasis in autism spectrum disorders

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Novel de novo SHANK3 mutation in autistic patients

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SHANK1 Deletions in Males with Autism Spectrum Disorder

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Disruption of the ProSAP2 Gene in a t(12;22)(q24.1;q13.3) Is Associated with the 22q13.3 Deletion Syndrome

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Characterization of the Shank Family of Synaptic Proteins

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Identification of a Novel Cortactin SH3 Domain-Binding Protein and Its Localization to Growth Cones of Cultured Neurons

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Prevalence of SHANK3 variants in patients with different subtypes of autism spectrum disorders

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Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies

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Communication impairments in mice lacking Shank1: reduced levels of ultrasonic vocalizations and scent marking behavior

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Sociability and motor functions in Shank1 mutant mice

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Identification of a recurrent breakpoint within the <i>SHANK3</i> gene in the 22q13.3 deletion syndrome

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Proline-Rich Synapse-Associated Proteins ProSAP1 and ProSAP2 Interact with Synaptic Proteins of the SAPAP/GKAP Family

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Differential expression and dendritic transcript localization of Shank family members: identification of a dendritic targeting element in the 3′ untranslated region of Shank1 mRNA

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Breakpoint mapping by next generation sequencing reveals causative gene disruption in patients carrying apparently balanced chromosome rearrangements with intellectual deficiency and/or congenital malformations

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Neuropsychopathology in 7 patients with the 22q13 deletion syndrome: Presence of bipolar disorder and progressive loss of skills

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Disruption of glutamate receptors at Shank-postsynaptic platform in Alzheimer's disease

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Scaffold Proteins at the Postsynaptic Density

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Clozapine and haloperidol differentially regulate dendritic spine formation and synaptogenesis in rat hippocampal neurons

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Dysfunction of <i><scp>SHANK2</scp></i> and <i><scp>CHRNA7</scp></i> in a patient with intellectual disability and language impairment supports genetic epistasis of the two loci

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Interstitial 22q13 deletions: genes other than SHANK3 have major effects on cognitive and language development

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Absence of deficits in social behaviors and ultrasonic vocalizations in later generations of mice lacking neuroligin4

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Disassembly of Shank and Homer Synaptic Clusters Is Driven by Soluble β-Amyloid1-40 through Divergent NMDAR-Dependent Signalling Pathways

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Phelan-McDermid syndrome in two adult brothers: atypical bipolar disorder as its psychopathological phenotype?

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Novel variants of the SHANK3 gene in Japanese autistic patients with severe delayed speech development

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Frontotemporal Dementia Phenotype Associated with MAPT Gene Duplication

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Bipolar affective disorder and early dementia onset in a male patient with SHANK3 deletion

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A promoter variant of SHANK1 affects auditory working memory in schizophrenia patients and in subjects clinically at risk for psychosis

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Schizophrenia in a patient with subtelomeric duplication of chromosome 22q

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Olfactory Receptor-Related Duplicons Mediate a Microdeletion at 11q13.2q13.4 Associated with a Syndromic Phenotype

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A translocation between Xq21.33 and 22q13.33 causes an intragenic SHANK3 deletion in a woman with Phelan–McDermid syndrome and hypergonadotropic hypogonadism

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Phelan–McDermid syndrome: Clinical report of a 70‐year‐old woman

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Adult Phenotypes in Angelman- and Rett-Like Syndromes

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Ring chromosome 22 and mood disorders

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Bends in human mitotic metaphase chromosomes revisited: 15q11-13 is the most frequent non-random autosomal bend in blood cultures

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Excitatory/Inhibitory Balance and Circuit Homeostasis in Autism Spectrum Disorders

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Neurobiology of rodent self-grooming and its value for translational neuroscience

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The Inositol Trisphosphate/Calcium Signaling Pathway in Health and Disease

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SHANK proteins: roles at the synapse and in autism spectrum disorder

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Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: A Gradient of Severity in Cognitive Impairments

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Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects

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Autism-associated SHANK3 haploinsufficiency causes <i>I</i> _h channelopathy in human neurons

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Methylomic trajectories across human fetal brain development

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Reduction in parvalbumin expression not loss of the parvalbumin-expressing GABA interneuron subpopulation in genetic parvalbumin and shank mouse models of autism

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The DLGAP family: neuronal expression, function and role in brain disorders

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Dysbiosis of microbiome and probiotic treatment in a genetic model of autism spectrum disorders

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Autism, Gastrointestinal Symptoms and Modulation of Gut Microbiota by Nutritional Interventions

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Unifying Views of Autism Spectrum Disorders: A Consideration of Autoregulatory Feedback Loops

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AMPA Receptors as Therapeutic Targets for Neurological Disorders

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Shank Modulates Postsynaptic Wnt Signaling to Regulate Synaptic Development

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Shank2 Deletion in Parvalbumin Neurons Leads to Moderate Hyperactivity, Enhanced Self-Grooming and Suppressed Seizure Susceptibility in Mice

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T‐Brain‐1 – A Potential Master Regulator in Autism Spectrum Disorders

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GABA Neuronal Deletion of Shank3 Exons 14–16 in Mice Suppresses Striatal Excitatory Synaptic Input and Induces Social and Locomotor Abnormalities

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Striatal Transcriptome and Interactome Analysis of Shank3-overexpressing Mice Reveals the Connectivity between Shank3 and mTORC1 Signaling

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Microbiome-Mediated Upregulation of MicroRNA-146a in Sporadic Alzheimer’s Disease

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Actin-Dependent Alterations of Dendritic Spine Morphology in Shankopathies

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Inhibition of Trpv4 rescues circuit and social deficits unmasked by acute inflammatory response in a Shank3 mouse model of Autism

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The Role of Synaptic Cell Adhesion Molecules and Associated Scaffolding Proteins in Social Affiliative Behaviors

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Shank3 Mice Carrying the Human Q321R Mutation Display Enhanced Self-Grooming, Abnormal Electroencephalogram Patterns, and Suppressed Neuronal Excitability and Seizure Susceptibility

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A longitudinal perspective on the pharmacotherapy of 24 adult patients with Phelan McDermid syndrome

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Shank3 Exons 14–16 Deletion in Glutamatergic Neurons Leads to Social and Repetitive Behavioral Deficits Associated With Increased Cortical Layer 2/3 Neuronal Excitability

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An Autism-Associated Neuroligin-3 Mutation Affects Developmental Synapse Elimination in the Cerebellum

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Selective Localization of Shanks to VGLUT1-Positive Excitatory Synapses in the Mouse Hippocampus

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Age-Related Changes in Pre- and Postsynaptic Partners of the Cholinergic C-Boutons in Wild-Type and SOD1G93A Lumbar Motoneurons

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Investigation of SHANK3 in schizophrenia

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SHANK genes in autism: Defining therapeutic targets

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Brain Lateralization in Mice Is Associated with Zinc Signaling and Altered in Prenatal Zinc Deficient Mice That Display Features of Autism Spectrum Disorder

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Synaptic basis of social dysfunction: a focus on postsynaptic proteins linking group‐ I m G lu R s with AMPAR s and NMDAR s

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The best-laid plans go oft awry: synaptogenic growth factor signaling in neuropsychiatric disease

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Effects of curcumin on synapses in APPswe/PS1dE9 mice

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Integrative Analysis of Brain Region-specific Shank3 Interactomes for Understanding the Heterogeneity of Neuronal Pathophysiology Related to SHANK3 Mutations

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Identification of ultra-rare genetic variants in pediatric acute onset neuropsychiatric syndrome (PANS) by exome and whole genome sequencing

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Chronic Treatment with Mood-Stabilizers Attenuates Abnormal Hyperlocomotion of GluA1-Subunit Deficient Mice

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