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Biomarkers of Parkinson’s disease: Present and future
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Protein biomarkers based on alpha-synuclein (SNCA) and dopamine (DA) metabolic products have yielded mixed results, do not reflect disease progression, and require an invasive lumbar puncture.
“In addition, protein biomarkers, such as those based on alpha‐synuclein (SNCA) and dopamine (DA) metabolic products have yielded mixed results, do not reflect disease progression and require an invasive lumbar puncture. 6”
From Validation of differentially expressed brain‐enriched microRNAs in the plasma of PD patients (2020) · cites this paper as [6]
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Biomarkers intersect with the exposome
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“[20] Chen H, Burton EA, Ross GW, Huang X, Savica R, Abbott RD, et al.”
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Molecular diagnostics of neurodegenerative disorders
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Validation of differentially expressed brain‐enriched microRNAs in the plasma of PD patients
Ravanidis, S., Bougea, A., Papagiannakis, N., Koros, C., Simitsi, A. M., Pachi, I., Breza, M., Stefanis, L., & Doxakis, E. (2020) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.51146 · Cited by 63
Cilento, E. M., Jin, L., Stewart, T., Shi, M., Sheng, L., & Zhang, J. (2019) · Journal of Neurochemistry · doi:10.1111/jnc.14635 · Cited by 60
Extracellular Vesicles as Novel Diagnostic and Prognostic Biomarkers for Parkinson’s Disease
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Metadata
- Authors
- Miller, D. B., & O’Callaghan, J. P.
- Venue
- Metabolism
- Publisher
- Elsevier BV
- Published
- 2015-03
- Volume
- 64
- Issue
- 3
- Pages
- S40-S46
- ISSN
- 0026-0495
- PMC
- PMC4721253
- Cited by
- 358
- References
- 4
- Language
- en
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