Molecular diagnostics of neurodegenerative disorders

The Amyloid Hypothesis of Alzheimer’s Disease: Progress and Problems on the Road to Therapeutics

Hardy, J., & Selkoe, D. J. (2002) · Science · doi:10.1126/science.1072994 · Cited by 13,864 · see citing works

Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy

Selenica, M.-L. B., Brownlow, M., Jimenez, J. P., Lee, D. C., Pena, G., Dickey, C. A., Gordon, M. N., & Morgan, D. (2013) · Neurodegenerative Diseases · doi:10.1159/000337230 · Cited by 10,359 · see citing works

Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS

DeJesus-Hernandez, M., Mackenzie, I. R., Boeve, B. F., Boxer, A. L., Baker, M., Rutherford, N. J., Nicholson, A. M., Finch, N. A., Flynn, H., Adamson, J., et al. (2011) · Neuron · doi:10.1016/j.neuron.2011.09.011 · Cited by 4,936 · see citing works

Hereditary Early-Onset Parkinson's Disease Caused by Mutations in <i>PINK1</i>

Valente, E. M., Abou-Sleiman, P. M., Caputo, V., Muqit, M. M. K., Harvey, K., Gispert, S., Ali, Z., Del Turco, D., Bentivoglio, A. R., Healy, D. G., et al. (2004) · Science · doi:10.1126/science.1096284 · Cited by 3,481 · see citing works

Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism

Bonifati, V., Rizzu, P., van Baren, M. J., Schaap, O., Breedveld, G. J., Krieger, E., Dekker, M. C. J., Squitieri, F., Ibáñez, P., Joosse, M., et al. (2003) · Science · doi:10.1126/science.1077209 · Cited by 2,800 · see citing works

The ubiquitin pathway in Parkinson's disease

Leroy, E., Boyer, R., Auburger, G. W. J., Leube, B., Ulm, G., Mezey, É., Harta, G., Brownstein, M., Jonnalagada, S., Chernova, T., et al. (1998) · Nature · doi:10.1038/26652 · Cited by 1,572 · see citing works

Alzheimer’s disease β-amyloid peptides are released in association with exosomes

Rajendran, L., Honsho, M., Zahn, T. R., Keller, P., Geiger, K. D., Verkade, P., & Simons, K. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0603838103 · Cited by 1,343 · see citing works

Plasma phospholipids identify antecedent memory impairment in older adults

Mapstone, M. E., Cheema, A. K., Fiandaca, M. S., Zhong, X., Mhyre, T. R., MacArthur, L. H., Hall, W. J., Fisher, S. G., Peterson, D. R., Haley, J. M., et al. (2014) · Nature Medicine · doi:10.1038/nm.3466 · Cited by 1,031 · see citing works

Review Article: Genetics of Alzheimer Disease

Bekris, L. M., Yu, C.-E., Bird, T. D., & Tsuang, D. W. (2010) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988710383571 · Cited by 1,029 · see citing works

Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease

Saman, S., Kim, W., Raya, M., Visnick, Y., Miro, S., Saman, S., Jackson, B., McKee, A. C., Alvarez, V. E., Lee, N. C. Y., et al. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.277061 · Cited by 985 · see citing works

Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission

Alvarez‐Erviti, L., Seow, Y., Schapira, A. H. V., Gardiner, C., Sargent, I. L., Wood, M. J. A., & Cooper, J. A. D. (2011) · Neurobiology of Disease · doi:10.1016/j.nbd.2011.01.029 · Cited by 741 · see citing works

Decreased β-Amyloid_1-42and Increased Tau Levels in Cerebrospinal Fluid of Patients With Alzheimer Disease

Sunderland, T., Linker, G., Mirza, N., Putnam, K. T., Friedman, D. L., Kimmel, L. H., Bergeson, J., Manetti, G. J., Zimmermann, M., Tang, B., et al. (2003) · JAMA · doi:10.1001/jama.289.16.2094 · Cited by 656 · see citing works

Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease

Philips, T., & Robberecht, W. (2011) · The Lancet Neurology · doi:10.1016/s1474-4422(11)70015-1 · Cited by 646 · see citing works

Release of exosomes from differentiated neurons and its regulation by synaptic glutamatergic activity

Lachenal, G. M., Pernet‐Gallay, K., Chivet, M., Hemming, F. J., Belly, A., Bodon, G., Blot, B., Haase, G., Goldberg, Y., & Sadoul, R. (2010) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2010.11.004 · Cited by 595 · see citing works

Mild cognitive impairment: prevalence, prognosis, aetiology, and treatment

DeCarli, C. S. (2002) · The Lancet Neurology · doi:10.1016/s1474-4422(03)00262-x · Cited by 569 · see citing works

Exosomes: Novel Biomarkers for Clinical Diagnosis

Jin, L., Li, J., Huang, B., Liu, J., Chen, X., Chen, X., Xu, Y., Huang, L., & Wang, X. (2015) · The Scientific World JOURNAL · doi:10.1155/2015/657086 · Cited by 567 · see citing works

Systematic analysis of microRNA expression of RNA extracted from fresh frozen and formalin-fixed paraffin-embedded samples

Xi, Y., Nakajima, G., Gavin, E. J., Morris, C. G., Kudo, K., Hayashi, K., & Ju, J. (2007) · RNA · doi:10.1261/rna.642907 · Cited by 567 · see citing works

Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease

Borovečki, F., Lovrečić, L., Zhou, J., Jeong, H., Then, F., Rosas, H. D., Hersch, S. M., Hogarth, P., Bouzou, B., Jensen, R. V., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504921102 · Cited by 413 · see citing works

Amyotrophic Lateral Sclerosis: A Focus on Disease Progression

Calvo, A. C., Manzano, R., de Mendonça, D. M. F., Muñoz, M. J., Zaragoza, P., & Osta, R. (2014) · BioMed Research International · doi:10.1155/2014/925101 · Cited by 404 · see citing works

Biomarkers of Parkinson’s disease: Present and future

Miller, D. B., & O'Callaghan, J. P. (2014) · Metabolism · doi:10.1016/j.metabol.2014.10.030 · Cited by 403 · see citing works

Increased oxidative damage to DNA in ALS patients

Bogdanov, M. B., Brown, R. H., Matson, W. R., Smart, R. J., Hayden, D. L., O’Donnell, H. C., Beal, M. F., & Cudkowicz, M. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00349-x · Cited by 334 · see citing works

Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington’s disease patients

Wild, E. J., Boggio, R., Langbehn, D. R., Robertson, N., Salman, H., Miller, J. R. C., Zetterberg, H., Leavitt, B. R., Kuhn, R. R., Tabrizi, S. J., et al. (2015) · Journal of Clinical Investigation · doi:10.1172/jci80743 · Cited by 265 · see citing works

Clinical applications of neuropsychological assessment.

Harvey, P. D. (2012) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2012.14.1/pharvey · Cited by 265 · see citing works

Identification of blood microRNAs associated to Parkinsońs disease

Margis, R., Margis, R., & Rieder, C. R. M. (2011) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2011.01.023 · Cited by 263 · see citing works

Genetic engineering of mouse embryonic stem cells by Nurr1 enhances differentiation and maturation into dopaminergic neurons

Chung, S., Sonntag, K., Andersson, T., Björklund, L. M., Park, J., Kim, D., Kang, U. J., Ole Isacson, A., & Kim, K. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.02255.x · Cited by 250 · see citing works

The Evolution of Diagnosis in Early Parkinson Disease

Jankovic, J. J. (2000) · Archives of Neurology · doi:10.1001/archneur.57.3.369 · Cited by 229 · see citing works

Increased oxidative damage and mitochondrial abnormalities in the peripheral blood of Huntington’s disease patients

Chen, C., Wu, Y., Cheng, M., Liu, J., Lee, Y., Lee, P.-W., Soong, B., & Chiu, D. T.-Y. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.05.093 · Cited by 226 · see citing works

Proteomic Profiling of Plasma in Huntington's Disease Reveals Neuroinflammatory Activation and Biomarker Candidates

Dalrymple, A., Wild, E. J., Joubert, R., Sathasivam, K., Björkqvist, M., Petersén, Å., Jackson, G. S., Isaacs, J. D., Kristiansen, M., Bates, G. P., et al. (2007) · Journal of Proteome Research · doi:10.1021/pr0700753 · Cited by 223 · see citing works

Circulating miRNAs as Biomarkers for Neurodegenerative Disorders

Grasso, M., Piscopo, P., Confaloni, A., & Denti, M. (2014) · Molecules · doi:10.3390/molecules19056891 · Cited by 187 · see citing works

Neuronal dark matter: the emerging role of microRNAs in neurodegeneration

Goodall, E. F., Heath, P. R., Bandmann, O., Kirby, J., & Shaw, P. J. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00178 · Cited by 187 · see citing works

In Vitro Analysis of Huntingtin-Mediated Transcriptional Repression Reveals Multiple Transcription Factor Targets

Zhai, W., Jeong, H., Cui, L., Krainc, D., & Tjian, R. (2005) · Cell · doi:10.1016/j.cell.2005.10.030 · Cited by 179 · see citing works

Significant Linkage of Parkinson Disease to Chromosome 2q36-37

Pankratz, N., Nichols, W. C., Uniacke, S. K., Halter, C. A., Rudolph, A., Shults, C. W., Conneally, P. M., & Foroud, T. (2003) · The American Journal of Human Genetics · doi:10.1086/374383 · Cited by 161 · see citing works

Identification of Epigenetically Altered Genes in Sporadic Amyotrophic Lateral Sclerosis

Figueroa‐Romero, C., Hur, J., Bender, D. E., Delaney, C. E., Cataldo, M. D., Smith, A. L., Yung, R. L., Ruden, D. M., Callaghan, B. C., & Feldman, E. L. (2012) · PLoS ONE · doi:10.1371/journal.pone.0052672 · Cited by 161 · see citing works

Development of biomarkers for Huntington's disease

Weir, D. W., Sturrock, A., & Leavitt, B. R. (2011) · The Lancet Neurology · doi:10.1016/s1474-4422(11)70070-9 · Cited by 159 · see citing works

Plasma microRNA biomarkers for detection of mild cognitive impairment

Sheinerman, K. S., Tsivinsky, V. G., Crawford, F., Mullan, M. J., Abdullah, L., & Umansky, S. R. (2012) · Aging · doi:10.18632/aging.100486 · Cited by 158 · see citing works

Sleep and circadian rhythm alterations correlate with depression and cognitive impairment in Huntington's disease

Aziz, N. A., Anguelova, G. V., Marinus, J., Lammers, G. J., & Roos, R. A. C. (2010) · Parkinsonism &amp; Related Disorders · doi:10.1016/j.parkreldis.2010.02.009 · Cited by 155 · see citing works

Aggregation and neurotoxicity of α-synuclein and related peptides

EI-Agnaf, O. M. A., & Irvine, G. B. (2002) · Biochemical Society Transactions · doi:10.1042/bst0300559 · Cited by 151 · see citing works

Small RNA sequencing-microarray analyses in Parkinson leukocytes reveal deep brain stimulation-induced splicing changes that classify brain region transcriptomes

Soreq, L., Salomonis, N., Bronstein, M., Greenberg, D., Israel, Z. H., Bergman, H., & Soreq, H. (2013) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2013.00010 · Cited by 124 · see citing works

Biomarkers of neurodegenerative disorders: How good are they?

Rachakonda, V., Pan, T. H., & Le, W. D. (2004) · Cell Research · doi:10.1038/sj.cr.7290235 · Cited by 116 · see citing works

Peripheral blood gene expression patterns discriminate among chronic inflammatory diseases and healthy controls and identify novel targets

Meskó, B., Poliskal, S., Szegedi, A., Szekanecz, Z., Palatka, K., Papp, M., & Nagy, L. (2010) · BMC Medical Genomics · doi:10.1186/1755-8794-3-15 · Cited by 116 · see citing works

A molecular signature in blood identifies early Parkinson’s disease

Molochnikov, L., Rabey, J. M., Dobronevsky, E., Bonuccelli, U., Ceravolo, R., Frosini, D., Grünblatt, E., Riederer, P. F., Jacob, C., Aharon‐Peretz, J., et al. (2012) · Molecular Neurodegeneration · doi:10.1186/1750-1326-7-26 · Cited by 113 · see citing works

Amyloid Precursor Protein Associates with a Nicastrin-Dependent Docking Site on the Presenilin 1–γ-Secretase Complex in Cells Demonstrated by Fluorescence Lifetime Imaging

Berezovska, O., Ramdya, P. P., Skoch, J. M., Wolfe, M. S., Bacskai, B. J., & Hyman, B. T. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-11-04560.2003 · Cited by 108 · see citing works

Stem cells in brain plasticity and repair

Peterson, D. (2002) · Current Opinion in Pharmacology · doi:10.1016/s1471-4892(01)00118-7 · Cited by 107 · see citing works

Transcriptional modulator H2A histone family, member Y ( H2AFY ) marks Huntington disease activity in man and mouse

Hu, Y., Chopra, V., Chopra, R., Locascio, J. J., Liao, Z., Ding, H., Zheng, B., Matson, W. R., Ferrante, R. J., Rosas, H. D., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1104409108 · Cited by 101 · see citing works

Dysregulation of Gene Expression in Primary Neuron Models of Huntington's Disease Shows That Polyglutamine-Related Effects on the Striatal Transcriptome May Not Be Dependent on Brain Circuitry

Runne, H., Régulier, E., Kuhn, A., Zala, D., Gökçe, Ö., Perrin, V., Sick, B., Aebischer, P., Déglon, N., & Luthi‐Carter, R. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.3044-08.2008 · Cited by 94 · see citing works

A multicenter assessment of dopamine transporter imaging with DOPASCAN/SPECT in parkinsonism

Parkinson Study Group (2000) · Neurology · doi:10.1212/wnl.55.10.1540 · Cited by 94 · see citing works

Advances in the detection of Alzheimer's disease-use of cerebrospinal fluid biomarkers.

Sjögren, M., Andreasen, N., & Blennow, K. (2003) · Clinica chimica acta; international journal of clinical chemistry · doi:10.1016/s0009-8981(03)00121-9 · Cited by 88 · see citing works

Biomarkers in the diagnosis and management of Alzheimer’s disease

Wurtman, R. J. (2014) · Metabolism · doi:10.1016/j.metabol.2014.10.034 · Cited by 86 · see citing works

Exosomes-associated neurodegeneration and progression of Parkinson's disease.

Russo, I., Bubacco, L., & Greggio, E. (2012) · Europe PMC (PubMed Central) · Cited by 85 · see citing works

Huntington’s disease biomarker progression profile identified by transcriptome sequencing in peripheral blood

Mastrokolias, A., Ariyürek, Y., Goeman, J. J., van Duijn, E., Roos, R. A. C., van der Mast, R. C., van Ommen, G. B., den Dunnen, J. T., Hoen, P. A. C. ’., & van Roon‐Mom, W. (2015) · European Journal of Human Genetics · doi:10.1038/ejhg.2014.281 · Cited by 85 · see citing works

Increased thirst and drinking in Huntington's disease and the R6/2 mouse

Wood, N. I., Goodman, A. O. G., van der Burg, J. M. M., Gazeau, V., Brundin, P., Björkqvist, M., Petersén, Å., Tabrizi, S. J., Barker, R. A., & Morton, A. J. (2008) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2007.12.007 · Cited by 83 · see citing works

Blood Biomarkers for Amyotrophic Lateral Sclerosis: Myth or Reality?

Robelin, L., & de Aguilar, J. G. (2014) · BioMed Research International · doi:10.1155/2014/525097 · Cited by 75 · see citing works

Clinical features and neuroimaging of PARK7‐linked parkinsonism

Dekker, M. C. J., Bonifati, V., Swieten, J. C. V., Leenders, N., Galjaard, R. H., Snijders, P. J. L. M., Horstink, M. W. I. M., Heutink, P., Oostra, B. A., & van Duijn, C. M. (2003) · Movement Disorders · doi:10.1002/mds.10422 · Cited by 74 · see citing works

Aberrant Regulation of DNA Methylation in Amyotrophic Lateral Sclerosis: A New Target of Disease Mechanisms

Martin, L. J., & Wong, M. (2013) · Neurotherapeutics · doi:10.1007/s13311-013-0205-6 · Cited by 71 · see citing works

Electrodiagnosis in Persons With Amyotrophic Lateral Sclerosis

Joyce, N. C., & Carter, G. T. (2013) · PM&R · doi:10.1016/j.pmrj.2013.03.020 · Cited by 71 · see citing works

Four Decades of Neurodegenerative Disease Research: How Far We Have Come!

Young, A. B. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.3767-09.2009 · Cited by 65 · see citing works

Positron emission tomography neuroimaging in Parkinson's disease.

Loane, C., & Politis, M. (2011) · PubMed · Cited by 63 · see citing works

Using iPS Cells toward the Understanding of Parkinson’s Disease

Torrent, R., Rigotti, F., Dell’Era, P., Memo, M., Raya, Á., & Consiglio, A. (2015) · Journal of Clinical Medicine · doi:10.3390/jcm4040548 · Cited by 60 · see citing works

Magnetic Resonance Spectroscopy: An In Vivo Molecular Imaging Biomarker for Parkinson’s Disease?

Ciurleo, R., Lorenzo, G. D., Bramanti, P., & Marino, S. (2014) · BioMed Research International · doi:10.1155/2014/519816 · Cited by 60 · see citing works

CYSTM, a novel cysteine-rich transmembrane module with a role in stress tolerance across eukaryotes

Venâncio, T. M., & Aravind, L. (2009) · Bioinformatics · doi:10.1093/bioinformatics/btp647 · Cited by 59 · see citing works

A longitudinal study of magnetic resonance spectroscopy Huntington's disease biomarkers

Sturrock, A., Laule, C., Wyper, K., MILNER, R. A., Decolongon, J., Santos, R. D., Coleman, A., Carter, K., Creighton, S., Bechtel, N., et al. (2015) · Movement Disorders · doi:10.1002/mds.26118 · Cited by 57 · see citing works

Time course of oxidant markers and antioxidant defenses in subgroups of amyotrophic lateral sclerosis patients

Cova, E., Bongioanni, P., Cereda, C., Metelli, M. R., Salvaneschi, L., Bernuzzi, S., Guareschi, S., Rossi, B., & Ceroni, M. (2010) · Neurochemistry International · doi:10.1016/j.neuint.2010.02.004 · Cited by 54 · see citing works

In vivo amyloid imaging in Alzheimer?s disease

Sair, H. I., Doraiswamy, P. M., & Petrella, J. R. (2004) · Neuroradiology · doi:10.1007/s00234-003-1034-9 · Cited by 50 · see citing works

State of the art review: Molecular diagnosis of inherited movement disorders. Movement Disorders Society task force on molecular diagnosis

Gasser, T., Bressman, S., Dürr, A., Higgins, J., Klockgether, T., & Myers, R. H. (2003) · Movement Disorders · doi:10.1002/mds.10338 · Cited by 42 · see citing works

Longitudinal Metabolite Changes in Huntington's Disease During Disease Onset

van den Bogaard, S. J. A., Dumas, E. M., Teeuwisse, W. M., Kan, H. E., WEBB, A. G., van Buchem, M. A., Roos, R. A. C., & van der Grond, J. (2014) · Journal of Huntington s Disease · doi:10.3233/jhd-140117 · Cited by 37 · see citing works

[ 123 I]β-CIT single-photon emission tomography in Parkinson's disease reveals a smaller decline in dopamine transporters with age than in controls

Tissingh, G., Bergmans, P., Booij, J., Winogrodzka, A., Stoof, J. C., Wolters, E. C., & van Royen, E. A. (1997) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/bf01254252 · Cited by 35 · see citing works

Reduced expression of metabotropic glutamate receptor 2mRNA in T cells of ALS patients

Poulopoulou, C., Davaki, P., Koliaraki, V., Kolovou, D., Markakis, I. A., & Vassilopoulos, D. (2005) · Annals of Neurology · doi:10.1002/ana.20675 · Cited by 34 · see citing works

Gene expression changes in blood as a putative biomarker for Huntington's disease

Lovrečić, L., Kastrin, A., Kobal, J., Pirtošek, Z., Krainc, D., & Peterlin, B. (2009) · Movement Disorders · doi:10.1002/mds.22477 · Cited by 30 · see citing works

EFNS task force on molecular diagnosis of neurologic disorders Guidelines for the molecular diagnosis of inherited neurologic diseases Second of two parts

Members of the task force on molecular diagnosis of neurologic disorders: T. Gasser, G. M. D. (2001) · European Journal of Neurology · doi:10.1046/j.1468-1331.2001.00228.x · Cited by 22 · see citing works

Reticulons as Markers of Neurological Diseases: Focus on Amyotrophic Lateral Sclerosis

Fergani, A., Dupuis, L., Jokic, N., Larmet, Y., de Tapia, M., René, F., Loeffler, J., & de Aguilar, J. G. (2005) · Neurodegenerative Diseases · doi:10.1159/000089624 · Cited by 17 · see citing works

EFNS task force on molecular diagnosis of neurologic disorders Guidelines for the molecular diagnosis of inherited neurologic diseases First of two parts

Gasser, T., Dichgans, M., Finsterer, J., Hausmanowa-Petrusewicz, I., Jurkat-Rott, K., Klopstock, T., Leguern, E., Lehesjoki, A., Lehmann-Horn, F., Lynch, T., et al. (2001) · European Journal of Neurology · doi:10.1046/j.1468-1331.2001.00226.x · Cited by 16 · see citing works

Establishing the psychometric underpinning of cognition measures for clinical trials of Alzheimer's disease and its precursors: A new approach

Posner, H. B., Cano, S., Carrillo, M. C., Selnes, O. A., Stern, Y., Thomas, R. G., Zajicek, J., Hobart, J. C., & Initiative, A. D. N. (2013) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2012.10.008 · Cited by 13 · see citing works

Correlative 99m Tc-labeled tropane derivative single photon emission computer tomography and clinical assessment in the staging of parkinson disease

Shinto, A., Antony, J., Kamaleshwaran, K. K., Vijayan, K., Selvan, A., Korde, A. G., Kameswaran, M., & Samuel, G. (2014) · World Journal of Nuclear Medicine · doi:10.4103/1450-1147.144818 · Cited by 12 · see citing works

Biofluid-based microRNA Biomarkers for Parkinsons Disease: an Overview and Update

Shinde, S., Mukhopadhyay, S., Mohsen, G. M., & Khoo, S. K. (2015) · AIMS Medical Science · doi:10.3934/medsci.2015.1.15 · Cited by 12 · see citing works

Le corps de Lewy, marqueur abusif de la maladie de Parkinson ?

Duyckaerts, C. J., & Hauw, J. (2003) · Bulletin de l Académie Nationale de Médecine · doi:10.1016/s0001-4079(19)34049-x · Cited by 7 · see citing works

Advances in Diagnostics for Neurodegenerative Disorders

Bokde, A. L. W., Meaney, J. F. M., Sheehy, N. P., Reilly, R. B., Abrahams, S., & Doherty, C. P. (2011) · Springer eBooks · doi:10.1007/978-1-84996-011-3_2 · Cited by 3 · see citing works

Development of Biomarkers

Wehling, M. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800687-0.00014-1 · Cited by 3 · see citing works

Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on Neuroinflammation

Lima Giacobbo, B., Doorduin, J., Klein, H. C., Dierckx, R. A. J. O., Bromberg, E., & de Vries, E. F. J. (2019) · Molecular Neurobiology · doi:10.1007/s12035-018-1283-6 · Cited by 750 · see citing works

Epidemiology of amyotrophic lateral sclerosis: an update of recent literature

Longinetti, E., & Fang, F. (2019) · Current Opinion in Neurology · doi:10.1097/wco.0000000000000730 · Cited by 620 · see citing works

Brain lipidomics: From functional landscape to clinical significance

Yoon, J. H., Seo, Y., Jo, Y. S., Lee, S., Cho, E., Cazenave-Gassiot, A., Shin, Y.-S., Moon, M. H., An, H. J., Wenk, M. R., et al. (2022) · Science Advances · doi:10.1126/sciadv.adc9317 · Cited by 324 · see citing works

Potential neuroprotective properties of epigallocatechin-3-gallate (EGCG)

Singh, N. A., Mandal, A. K. A., & Khan, Z. A. (2015) · Nutrition Journal · doi:10.1186/s12937-016-0179-4 · Cited by 319 · see citing works

Circulating brain-enriched microRNAs as novel biomarkers for detection and differentiation of neurodegenerative diseases

Sheinerman, K. S., Toledo, J. B., Tsivinsky, V. G., Irwin, D. J., Grossman, M., Weintraub, D. A., Hurtig, H. I., Chen‐Plotkin, A. S., Wolk, D. A., McCluskey, L. F., et al. (2017) · Alzheimer s Research & Therapy · doi:10.1186/s13195-017-0316-0 · Cited by 168 · see citing works

Small Non-coding RNAs: New Class of Biomarkers and Potential Therapeutic Targets in Neurodegenerative Disease

Watson, C. N., Belli, A., & Pietro, V. D. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.00364 · Cited by 148 · see citing works

Current Advances in The Development of Novel Polymeric Nanoparticles for The Treatment of Neurodegenerative Diseases

Cano, A., Sánchez-López, E., Ettcheto, M., López-Machado, A., Espina, M., Souto, E. B., Galindo, R., Camins, A., García, M. L., & Turowski, P. (2020) · Nanomedicine · doi:10.2217/nnm-2019-0443 · Cited by 144 · see citing works

Neurotheranostics as Personalized Medicines

Kevadiya, B. D., Ottemann, B. M., Thomas, M. B., Mukadam, I., Nigam, S., McMillan, J., Gorantla, S., Bronich, T. K., Edagwa, B., & Gendelman, H. E. (2019) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2018.10.011 · Cited by 124 · see citing works

Mitochondrial dysfunctions, oxidative stress and neuroinflammation as therapeutic targets for neurodegenerative diseases: An update on current advances and impediments

Rehman, M. U., Sehar, N., Dar, N. J., Khan, A., Arafah, A., Rashid, S., Rashid, S. M., & Ganaie, M. A. (2023) · Neuroscience &amp; Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104961 · Cited by 130 · see citing works

Reactive Oxygen Species and Their Impact in Neurodegenerative Diseases: Literature Landscape Analysis

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Alzheimer disease pathology and the cerebrospinal fluid proteome

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Decoding Neurodegeneration: A Review of Molecular Mechanisms and Therapeutic Advances in Alzheimer’s, Parkinson’s, and ALS

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Exploring the reproducibility of functional connectivity alterations in Parkinson’s disease

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Neuroprotective Properties of Green Tea (Camellia sinensis) in Parkinson’s Disease: A Review

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Molecular Biomarkers and Their Implications for the Early Diagnosis of Selected Neurodegenerative Diseases

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Stem Cell Transplantation Therapy and Neurological Disorders: Current Status and Future Perspectives

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Evidence to Consider Angiotensin II Receptor Blockers for the Treatment of Early Alzheimer’s Disease

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Genetic testing and genetic counseling for amyotrophic lateral sclerosis: an update for clinicians

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Potential Role of Natural Polyphenols against Protein Aggregation Toxicity: In Vitro, In Vivo, and Clinical Studies

Henríquez, G., Gomez, A., Guerrero, E., & Narayan, M. (2020) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.0c00381 · Cited by 83 · see citing works

Conifers Phytochemicals: A Valuable Forest with Therapeutic Potential

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Modeling neurodegenerative disorders in zebrafish

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Multi-cohort cerebrospinal fluid proteomics identifies robust molecular signatures across the Alzheimer disease continuum

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Minimally Invasive Nasal Depot (MIND) technique for direct BDNF AntagoNAT delivery to the brain

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Perspectives on the recent developments with green tea polyphenols in drug discovery.

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Brain-Derived Neurotrophic Factor: A Novel Dynamically Regulated Therapeutic Modulator in Neurological Disorders

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Towards Modern-Age Advanced Sensors for the Management of Neurodegenerative Disorders: Current Status, Challenges and Prospects

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Role of Tau in Various Tauopathies, Treatment Approaches, and Emerging Role of Nanotechnology in Neurodegenerative Disorders

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A human-on-a-chip approach to tackling rare diseases

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Evaluation of Vertical Ground Reaction Forces Pattern Visualization in Neurodegenerative Diseases Identification Using Deep Learning and Recurrence Plot Image Feature Extraction

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Model-based whole-brain perturbational landscape of neurodegenerative diseases

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Perspectives on the Molecular Mediators of Oxidative Stress and Antioxidant Strategies in the Context of Neuroprotection and Neurolongevity: An Extensive Review

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MicroRNA biomarkers as next-generation diagnostic tools for neurodegenerative diseases: a comprehensive review

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Prediction of differentially expressed microRNAs in blood as potential biomarkers for Alzheimer’s disease by meta-analysis and adaptive boosting ensemble learning

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Probiotics as functional foods: How probiotics can alleviate the symptoms of neurological disabilities

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Recent Developments in Coumarin Derivatives as Neuroprotective Agents

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The GPR17 receptor-A promising goal for therapy and a potential marker of the neurodegenerative process in multiple sclerosis

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Long Non-Coding RNAs: New Insights in Neurodegenerative Diseases

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Targeting mTORs by omega-3 fatty acids: A possible novel therapeutic strategy for neurodegeneration?

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A Hybrid Fuzzy Clustering Approach for the Recognition and Visualization of MRI Images of Parkinson’s Disease

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A neutrosophic-entropy based adaptive thresholding segmentation algorithm: A special application in MR images of Parkinson's disease

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An 11-mer Amyloid Beta Peptide Fragment Provokes Chemical Mutations and Parkinsonian Biomarker Aggregation in Dopaminergic Cells: A Novel Road Map for “Transfected” Parkinson’s

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Drug Development for Alzheimer’s and Parkinson’s Disease: Where Do We Go Now?

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Pharmaceutical prospects of Silymarin for the treatment of neurological patients: an updated insight

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Review of β‐carboline and its derivatives as selective MAO‐A inhibitors

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RGS2 expression predicts amyloid-β sensitivity, MCI and Alzheimer’s disease: genome-wide transcriptomic profiling and bioinformatics data mining

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Cholesterol and Dementia: A Long and Complicated Relationship

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Syndecan-3 as a Novel Biomarker in Alzheimer’s Disease

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A neutrosophic-entropy based clustering algorithm (NEBCA) with HSV color system: A special application in segmentation of Parkinson’s disease (PD) MR images

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Point-of-Care Devices Using Disease Biomarkers To Diagnose Neurodegenerative Disorders

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Development of Neuro-Degenerative Diseases’ Gait Classification Algorithm Using Convolutional Neural Network and Wavelet Coherence Spectrogram of Gait Synchronization

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Viscous dynamics associated with hypoexcitation and structural disintegration in neurodegeneration via generative whole‐brain modeling

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Specific alterations in the circulating levels of the SIRT1, TLR4, and IL7 proteins in patients with dementia

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Epidemiology of Amyotrophic Lateral Sclerosis

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Man’s best friend in life and death: scientific perspectives and challenges of dog brain banking

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Traumatic brain injury and the development of parkinsonism: Understanding pathophysiology, animal models, and therapeutic targets

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Chaperone-Dependent Mechanisms as a Pharmacological Target for Neuroprotection

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Network Analysis Identifies Disease-Specific Pathways for Parkinson’s Disease

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Pharmacological Activities and Molecular Mechanisms of Sinapic Acid in Neurological Disorders

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Molecular basis of chronic neurodegeneration

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Identification of Neurodegenerative Diseases Based on Vertical Ground Reaction Force Classification Using Time–Frequency Spectrogram and Deep Learning Neural Network Features

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Natural polyphenols based new therapeutic avenues for advanced biomedical applications

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DNA Methylation Profiles in Whole Blood of Huntington's Disease Patients

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ncRDense: A novel computational approach for classification of non-coding RNA family by deep learning

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Elucidating Critical Proteinopathic Mechanisms and Potential Drug Targets in Neurodegeneration

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Rapid and Electronic Identification and Quantification of Age‐Specific Circulating Exosomes via Biologically Activated Graphene Transistors

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A comprehensive review of advanced focused ultrasound (FUS) microbubbles-mediated treatment of Alzheimer’s disease

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Targeting amyloid proteins for clinical diagnosis of neurodegenerative diseases

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Streptozotocin alters glucose transport, connexin expression and endoplasmic reticulum functions in neurons and astrocytes

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MRI visualization of neuroinflammation using VCAM-1 targeted paramagnetic micelles

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A cerebrospinal fluid microRNA analysis: Progressive supranuclear palsy

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Identification of technology frontiers of artificial intelligence-assisted pathology based on patent citation network

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Impact of diet-derived signaling molecules on human cognition: exploring the food–brain axis

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Parkinson’s disease research: adopting a more human perspective to accelerate advances

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Modulatory Activity of the Endocannabinoid System in the Development and Proliferation of Cells in the CNS

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Human Periapical Cyst-Derived Stem Cells Can Be A Smart “Lab-on-A-Cell” to Investigate Neurodegenerative Diseases and the Related Alteration of the Exosomes’ Content

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Biophysical models applied to dementia patients reveal links between geographical origin, gender, disease duration, and loss of neural inhibition

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Report on the Symposium “Molecular Mechanisms Involved in Neurodegeneration”

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Role of Biomarkers in Medicine

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Advances in Stem Cell Research- A Ray of Hope in Better Diagnosis and Prognosis in Neurodegenerative Diseases

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Diagnostic delay among ALS patients: Egyptian study

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The future of Parkinson’s disease research: A new paradigm of human-specific investigation is necessary… and possible

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Multi-cohort cerebrospinal fluid proteomics identifies robust molecular signatures for asymptomatic and symptomatic Alzheimer’s disease.Preprint

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Unlocking the Neuroprotective Potential of Silymarin: A Promising Ally in Safeguarding the Brain from Alzheimer’s Disease and Other Neurological Disorders

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Multiple Criteria Optimization (MCO): A gene selection deterministic tool in RStudio

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Fatty Acid-Binding Protein 7 (FABP-7), Glutamic Acid and Neurofilament Light Chain (NFL) as Potential Markers of Neurodegenerative Disorders in Psoriatic Patients—A Pilot Study

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Polymerase chain reaction with nearby primers

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Recognition and classification of facial expression using artificial intelligence as a key of early detection in neurological disorders

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Psoriasis and neurodegenerative diseases—a review

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Perspective on investigation of neurodegenerative diseases with neurorobotics approaches

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Cerebrospinal fluid transcripts may predict shunt surgery responses in normal pressure hydrocephalus

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The Other Side of Alzheimer’s Disease: Influence of Metabolic Disorder Features for Novel Diagnostic Biomarkers

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The Diagnostic Potential of Amyloidogenic Proteins

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Dietary NMN supplementation enhances motor and NMJ function in ALS

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