PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

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1. Dual PI3K/AKT/mTOR Inhibitor BEZ235 Synergistically Enhances the Activity of JAK2 Inhibitor against Cultured and Primary Human Myeloproliferative Neoplasm Cells
   Warren C. Fiskus, Srđan Verstovšek, Taghi Manshouri, Jacqueline E. Smith, Karissa Peth, Sunil Abhyankar, Joseph P. McGuirk, Kapil N. Bhalla · 2013 · Molecular Cancer Therapeutics
2. mTOR-Related Brain Dysfunctions in Neuropsychiatric Disorders
   Larisa Ryskalin, Fiona Limanaqi, Alessandro Frati, Carla Letizia Busceti, Francesco Fornai · 2018 · International Journal of Molecular Sciences
3. The Cross Talk Between p53 and mTOR Pathways in Response to Physiological and Genotoxic Stresses
   Danrui Cui, Ruirui Qu, Dian Liu, Xiufang Xiong, Tingbo Liang, Yongchao Zhao · 2021 · Frontiers in Cell and Developmental Biology
4. Regulation of TOR by small GTPases
   Durán, Raúl V, Hall, Michael N · 2012 · The EMBO Reports
5. The mTOR Pathway Controls Cell Proliferation by Regulating the FoxO3a Transcription Factor via SGK1 Kinase
   Shunsuke Mori, Shigeyuki Nada, Hironobu Kimura, Shoji Tajima, Yusuke Takahashi, Ayaka Kitamura, Chitose Oneyama, Masato Okada · 2014 · PLoS ONE
6. Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt
   Jinfang Zhang, Kai Lin Xu, Pengda Liu, Yan Geng, Bin Wang, Wenjian Gan, Jianping Guo, Fei Wu, Y. Rebecca Chin, Christian J. Berrios et al. · 2016 · Molecular Cell
7. Pathological hypertrophy amelioration by PRAS40-mediated inhibition of mTORC1
   Mirko Völkers, Haruhiro Toko, Shirin Doroudgar, Shabana Din, Pearl J. Quijada, Anya Y. Joyo, Luis Ornelas, Eri Joyo, Donna J. Thuerauf, Mathias H. Konstandin et al. · 2013 · Proceedings of the National Academy of Sciences
8. Cellular and molecular effects of the mTOR inhibitor everolimus
   Uttara Saran, Michelangelo Foti, Jean‐François Dufour · 2015 · Clinical Science
9. Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner
   Shaida Andrabi, Ole V. Gjoerup, Jennifer A. Kean, Thomas M. Roberts, Brian S. Schaffhausen · 2007 · Proceedings of the National Academy of Sciences
10. Signal transduction pathways in FSH regulation of rat Sertoli cell proliferation
    María Fernanda Riera, Mariana Regueira, María Noel Galardo, Eliana Herminia Pellizzari, Silvina Beatriz Meroni, Selva Beatriz Cigorraga · 2012 · American Journal of Physiology-Endocrinology and Metabolism
11. Recent Advances in Understanding Amino Acid Sensing Mechanisms that Regulate mTORC1
    Liufeng Zheng, Wei Zhang, Yuanfei Zhou, Fengna Li, Hongkui Wei, Jian Peng · 2016 · International Journal of Molecular Sciences
12. Current Perspectives on Akt Akt-ivation and Akt-ions
    Ronald W. Matheny, Martin Louis Adamo · 2009 · Experimental Biology and Medicine
13. Cryptotanshinone Inhibits Cancer Cell Proliferation by Suppressing Mammalian Target of Rapamycin–Mediated Cyclin D1 Expression and Rb Phosphorylation
    Wenxing Chen, Yan Luo, Lei Liu, Hongyu Zhou, Baoshan Xu, Xiuzhen Han, Tao Shen, Zhijun Liu, Yin Lu, Shile Huang · 2010 · Cancer Prevention Research
14. Critical roles for the TSC-mTOR pathway in β-cell function
    Hiroyuki Mori, Ken Inoki, Darren M. Opland, Heike Münzberg, Eneida C. Villanueva, Miro Faouzi, Tsuneo Ikenoue, David J. Kwiatkowski, Ormond A. MacDougald, Martin Grosvenor Myers et al. · 2009 · American Journal of Physiology-Endocrinology and Metabolism
15. Regulating Autophagy as a Therapeutic Target for Diabetic Nephropathy
    Munehiro Kitada, Yoshio Ogura, Itaru Monno, Daisuke Koya · 2017 · Current Diabetes Reports
16. Elevated Corticosterone Associated with Food Deprivation Upregulates Expression in Rat Skeletal Muscle of the mTORC1 Repressor, REDD1
    Nora K. McGhee, Leonard S. Jefferson, Scot R. Kimball · 2009 · Journal of Nutrition
17. Rheb controls misfolded protein metabolism by inhibiting aggresome formation and autophagy
    Xiaoming Zhou, Tsuneo Ikenoue, Xiaowei Chen, Li Li, Ken Inoki, Kun‐Liang Guan · 2009 · Proceedings of the National Academy of Sciences
18. Dietary zinc deficiency reduced growth performance, intestinal immune and physical barrier functions related to NF-κB, TOR, Nrf2, JNK and MLCK signaling pathway of young grass carp ( Ctenopharyngodon idella )
    Zheng-Xing Song, Wei‐Dan Jiang, Yang Liu, Pei Wu, Jun Jiang, Xiao‐Qiu Zhou, Sheng‐Yao Kuang, Ling Yin Tang, Wu‐Neng Tang, Yong‐An Zhang et al. · 2017 · Fish & Shellfish Immunology
19. Rheb and Rags come together at the lysosome to activate mTORC1
    Groenewoud, Marlous J., Zwartkruis, Fried J.T. · 2013 · Biochemical Society Transactions
20. Fish oil targets PTEN to regulate NFκB for downregulation of anti-apoptotic genes in breast tumor growth
    Triparna Ghosh-Choudhury, Chandi Charan Mandal, Kathleen A. Woodruff, Patricia St. Clair, Gabriel Fernandes, Goutam Ghosh Choudhury, Nandini Ghosh‐Choudhury · 2008 · Breast Cancer Research and Treatment
21. mTORC1 signaling and IL‐17 expression: Defining pathways and possible therapeutic targets
    Wenkai Ren, Jie Yin, Jielin Duan, Gang Liu, Bie Tan, Guan Yang, Guoyao Wu, Fuller W. Bazer, Yuanyi Peng, Yulong Yin · 2015 · European Journal of Immunology
22. The IKK‐related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists
    Çağrı Bodur, Dubek Kazyken, Kezhen Huang, Bilgen Ekim Üstünel, Kate A Siroky, Aaron Seth Tooley, Ian E. Gonzalez, Daniel H. Foley, Hugo A. Acosta-Jaquez, Tammy M. Barnes et al. · 2017 · The EMBO Journal
23. Epidermal mTORC1 Signaling Contributes to the Pathogenesis of Psoriasis and Could Serve as a Therapeutic Target
    Claudia Buerger · 2018 · Frontiers in Immunology
24. Role of AMP‐Activated Protein Kinase in Cancer Therapy
    Gauhar Rehman, Adeeb Shehzad, Abdul Latif Khan, Muhammad Hamayun · 2014 · Archiv der Pharmazie
25. Neurofibromatosis-1 regulates mTOR-mediated astrocyte growth and glioma formation in a TSC/Rheb-independent manner
    Sutapa Banerjee, Nikkilina R. Crouse, Ryan J. Emnett, Scott M. Gianino, David H. Gutmann · 2011 · Proceedings of the National Academy of Sciences
26. mTORC1 directly phosphorylates and activates ERα upon estrogen stimulation
    Anya Alayev, Rachel S. Salamon, Sara Malka Berger, Naomi S. Schwartz, Rafael Cuesta, Rose B. Snyder, Marina K. Holz · 2015 · Oncogene
27. Regulation of mTORC1 by Upstream Stimuli
    Chase H. Melick, Jenna L. Jewell · 2020 · Genes
28. Emerging regulatory mechanisms and functions of biomolecular condensates: implications for therapeutic targets
    Soyoung Jeon, Yeram Jeon, Ji-Youn Lim, Yujeong Kim, Boksik Cha, Wantae Kim · 2025 · Signal Transduction and Targeted Therapy
29. Molecular mechanisms of mTOR regulation by stress
    Alexander Martin Heberle, Mirja Tamara Prentzell, Karen van Eunen, Barbara M. Bakker, Sushma Nagaraja Grellscheid, Kathrin Thedieck · 2014 · Molecular & Cellular Oncology
30. Tuberous sclerosis complex, implication from a rare genetic disease to common cancer treatment
    Ken Inoki, Kun‐Liang Guan · 2009 · Human Molecular Genetics
31. Mechanistically distinct cancer-associated mTOR activation clusters predict sensitivity to rapamycin
    Jianing Xu, Can G. Pham, Steven K. Albanese, Yiyu Dong, Toshinao Oyama, Chung‐Han Lee, Vanessa S. Rodrik-Outmezguine, Zhan Yao, Song Iy Han, David Chen et al. · 2016 · Journal of Clinical Investigation
32. Folliculin: A Regulator of Transcription Through AMPK and mTOR Signaling Pathways
    Josué M. J. Ramírez-Reyes, R. Cuesta, A. Pause · 2021 · Frontiers in Cell and Developmental Biology
33. The CRB1 and adherens junction complex proteins in retinal development and maintenance
    C. Henrique Alves, Lucie P. Pellissier, Jan Wijnholds · 2014 · Progress in Retinal and Eye Research
34. Body size regulation and insulin-like growth factor signaling
    Seogang Hyun · 2013 · Cellular and Molecular Life Sciences
35. Regulation of CD8+ T memory and exhaustion by the mTOR signals
    Yao Chen, Ziyang Xu, Hongxiang Sun, Xinxing Ouyang, Yuheng Han, Haihui Yu, Ningbo Wu, Yiting Xie, Bing Su · 2023 · Cellular and Molecular Immunology
36. Mammalian target of rapamycin signaling in diabetic cardiovascular disease
    Chong, Zhao, Maiese, Kenneth · 2012 · Cardiovascular Diabetology
37. A small molecule inhibitor of Rheb selectively targets mTORC1 signaling
    Sarah J. Mahoney, Sridhar Narayan, Lisa Molz, Lauren A. Berstler, Seong Anthony Woo Kang, George P. Vlasuk, Eddine Saiah · 2018 · Nature Communications
38. Serine and one-carbon metabolism, a bridge that links mTOR signaling and DNA methylation in cancer.
    Ju-Deng Zeng, W. Wu, Hui-Yun Wang, Xiao-Xing Li · 2019 · Pharmacological Research
39. Focal adhesion kinase is required for IGF-I-mediated growth of skeletal muscle cells via a TSC2/mTOR/S6K1-associated pathway
    Hannah Crossland, Abid A. Kazi, Charles H. Lang, James A. Timmons, Philippe Pierre, Daniel James Wilkinson, Kenneth Smith, Nathaniel J. Szewczyk, Philip James Atherton · 2013 · American Journal of Physiology-Endocrinology and Metabolism
40. Deconvoluting mTOR biology
    Jason D. Weber, David H. Gutmann · 2012 · Cell Cycle
41. Targeting the genetic alterations of the PI3K–AKT–mTOR pathway: Its potential use in the treatment of bladder cancers
    Nadine Houédé, Philippe Pourquier · 2014 · Pharmacology & Therapeutics
42. Modulation of mTOR signaling as a strategy for the treatment of Pompe disease
    Jeong‐A Lim, Lishu Li, Orian S. Shirihai, Kyle M. Trudeau, Rosa Puertollano, Nina Raben · 2017 · EMBO Molecular Medicine
43. LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control
    Wenjian Gan, Xiaoming Dai, Xiangpeng Dai, Jun Xie, Shasha Yin, Junjie Zhu, Chen Wang, Yuchen Liu, Jianping Guo, Min Wang et al. · 2020 · Nature Cell Biology
44. Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis
    Alison L. Kearney, Dougall M. Norris, Milad Ghomlaghi, Martin Kin Lok Wong, Sean J. Humphrey, Luke Carroll, Guang Yang, Kristen C. Cooke, Pengyi Yang, Thomas A. Geddes et al. · 2021 · eLife
45. Aberrant mTOR activation in senescence and aging: A mitochondrial stress response?
    Timothy Nacarelli, Ashley Azar, Christian Sell · 2014 · Experimental Gerontology
46. AMP-activated Protein Kinase (AMPK) Control of mTORC1 Is p53- and TSC2-independent in Pemetrexed-treated Carcinoma Cells
    Stuti Agarwal, Catherine M. Bell, Scott B. Rothbart, Richard G. Moran · 2015 · Journal of Biological Chemistry
47. Mechanisms Involved in the Coordinate Regulation of mTORC1 by Insulin and Amino Acids
    Michael Don Dennis, Jamie Baum, Scot R. Kimball, Leonard S. Jefferson · 2011 · Journal of Biological Chemistry
48. mTOR Inhibitors Synergize on Regression, Reversal of Gene Expression, and Autophagy in Hepatocellular Carcinoma
    Hala Elnakat Thomas, Carol A. Mercer, Larissa S. Carnevalli, Jongsun Park, Jesper Bøje Andersen, Elizabeth A. Conner, Kazuhiro Tanaka, Tomoo Matsutani, Akio Iwanami, Bruce J. Aronow et al. · 2012 · Science Translational Medicine
49. Targeting mTOR for fighting diseases: A revisited review of mTOR inhibitors
    Tian Xu, Dejuan Sun, Yi Chen, Liang Ouyang · 2020 · European Journal of Medicinal Chemistry
50. PI3K/AKT Pathway and Its Mediators in Thyroid Carcinomas
    Zahra Nozhat, Mehdi Hedayati · 2015 · Molecular Diagnosis & Therapy
51. PI3K/Akt/mTOR Signaling Pathway and the Biphasic Effect of Arsenic in Carcinogenesis
    Qiao Yi Chen, Max Costa · 2018 · Molecular Pharmacology
52. Mammalian Target of Rapamycin Activator RHEB Is Frequently Overexpressed in Human Carcinomas and Is Critical and Sufficient for Skin Epithelial Carcinogenesis
    Zhi Hong Lu, Mark B. Shvartsman, Andrew Y. Lee, Jenny Meng Shao, Mollianne M. Murray, Raleigh D. Kladney, Dong Fan, Stan Krajewski, Gary Gene Chiang, Gordon Brent Mills et al. · 2010 · Cancer Research
53. A new player in the orchestra of cell growth: SREBP activity is regulated by mTORC1 and contributes to the regulation of cell and organ size
    Thomas Porstmann, Cláudio R. Santos, Caroline A. Lewis, Beatrice L. Griffiths, Almut Schulze · 2009 · Biochemical Society Transactions
54. Mammalian target of rapamycin as a therapeutic target in oncology
    Robert T. Abraham, Christina H. Eng · 2008 · Expert Opinion on Therapeutic Targets
55. Eccentric contractions increase the phosphorylation of tuberous sclerosis complex‐2 (TSC2) and alter the targeting of TSC2 and the mechanistic target of rapamycin to the lysosome
    Jacobs, Brittany L., You, Jae‐Sung, Frey, John W., Goodman, Craig A., Gundermann, David M., Hornberger, Troy A. · 2013 · The Journal of Physiology
56. Oxidant Stress and Signal Transduction in the Nervous System with the PI 3-K, Akt, and mTOR Cascade
    Maiese, Kenneth, Chong, Zhao Zhong, Wang, Shaohui, Shang, Yan Chen · 2012 · International Journal of Molecular Sciences
57. Beyond controlling cell size: functional analyses of S6K in tumorigenesis
    Xueji Wu, Wei Xie, Wen-Xuan Xie, Wen-Yi Wei, Jian-ping Guo · 2022 · Cell Death and Disease
58. Mechanical Stimulation Induces mTOR Signaling via an ERK-Independent Mechanism: Implications for a Direct Activation of mTOR by Phosphatidic Acid
    Jae Sung You, John W. Frey, Troy Alan Hornberger · 2012 · PLoS ONE
59. Traditional Chinese medicine for colorectal cancer treatment: potential targets and mechanisms of action
    Jinfang Chen, Shiwei Wu, Zi-Man Shi, Bing Hu · 2023 · Chinese Medicine
60. mTOR Signaling in T Cell Immunity and Autoimmunity
    Yu Liu, Datong Zhang, Xinguang Liu · 2014 · International Reviews of Immunology
61. PI3K/AKT/mTOR pathway in multiple myeloma: from basic biology to clinical promise
    Vijay G. Ramakrishnan, Shaji Kunnathu Kumar · 2018 · Leukemia & lymphoma/Leukemia and lymphoma
62. mTORC1 Overactivation as a Key Aging Factor in the Progression to Type 2 Diabetes Mellitus
    C. Guillén, M. Benito · 2018 · Frontiers in Endocrinology
63. Signaling pathways in the regulation of cancer stem cells and associated targeted therapy
    Manni Wang, Min Wu · 2022 · MedComm
64. Phosphorylation of PRAS40 on Thr246 by PKB/AKT facilitates efficient phosphorylation of Ser183 by mTORC1
    Emmani B. M. Nascimento, Marieke Snel, Bruno Guigas, Gerard C.M. van der Zon, Jan Kriek, J. Antonie Maassen, Ingrid M. Jazet, Michaëla Diamant, D. Margriet Ouwens · 2010 · Cellular Signalling
65. PI3K-AKT-mTOR-Signaling and beyond: the Complex Network in Gastroenteropancreatic Neuroendocrine Neoplasms
    Franziska Briest, Patricia Grabowski · 2014 · Theranostics
66. Pemetrexed Indirectly Activates the Metabolic Kinase AMPK in Human Carcinomas
    Scott B. Rothbart, Alexandra C. Racanelli, Richard G. Moran · 2010 · Cancer Research
67. Beclin-1: a therapeutic target at the intersection of autophagy, immunotherapy, and cancer treatment
    Zhumin Cao, Ke Tian, Yincheng Ran, Haonan Zhou, Lei Zhou, Yana Ding, Xiaowei Tang · 2024 · Frontiers in Immunology
68. A Role for p38 Stress-Activated Protein Kinase in Regulation of Cell Growth via TORC1
    Megan Cully, Alice Genevet, Patricia H. Warne, Caroline Treins, Tao Liu, Julie Bastien, Buzz Baum, Nicolas Tapon, Sally J. Leevers, Julian Downward · 2009 · Molecular and Cellular Biology
69. mTOR-Dependent Cell Proliferation in the Brain
    Ryskalin, Larisa, Lazzeri, Gloria, Flaibani, Marina, Biagioni, Francesca, Gambardella, Stefano, Frati, Alessandro, Fornai, Francesco · 2017 · BioMed Research International
70. DEPTOR at the Nexus of Cancer, Metabolism, and Immunity
    Alexandre Caron, David Michael Briscoe, Denis Richard, Mathieu Laplante · 2018 · Physiological Reviews
71. PI3K/mTORC1 activation in hamartoma syndromes: Therapeutic prospects
    Vera P. Krymskaya, Elena A. Goncharova · 2009 · Cell Cycle
72. Targeting the translational machinery as a novel treatment strategy for hematologic malignancies
    Patrick Ryan Hagner, Abraham Schneider, Ronald B. Gartenhaus · 2010 · Blood
73. TAK1 mediates convergence of cellular signals for death and survival
    Sabreena Aashaq, Asiya Batool, Khurshid Iqbal Andrabi · 2018 · APOPTOSIS
74. Plant target of rapamycin signaling network: Complexes, conservations, and specificities
    Yanlin Liu, Yan Xiong · 2021 · Journal of Integrative Plant Biology
75. G-protein–coupled receptor GPR161 is overexpressed in breast cancer and is a promoter of cell proliferation and invasion
    Michael E. Feigin, Bin Xue, Molly Hammell, Senthil K. Muthuswamy · 2014 · Proceedings of the National Academy of Sciences
76. PKCε contributes to lipid-induced insulin resistance through cross talk with p70S6K and through previously unknown regulators of insulin signaling
    Brandon M. Gassaway, Max C. Petersen, Yulia V. Surovtseva, Karl W. Barber, Joshua B. Sheetz, Hans R. Aerni, Jane S. Merkel, Varman T. Samuel, Gerald I. Shulman, Jesse Rinehart · 2018 · Proceedings of the National Academy of Sciences
77. mTORC1 senses stresses: Coupling stress to proteostasis
    Kuo‐Hui Su, Chengkai Dai · 2017 · BioEssays
78. Glucose starvation induces autophagy via ULK1-mediated activation of PIKfyve in an AMPK-dependent manner
    Cansu Karabiyik, Mariella Vicinanza, Sung Min Son, David Chaim Rubinsztein · 2021 · Developmental Cell
79. Predominant Role of mTOR Signaling in Skin Diseases with Therapeutic Potential
    Fani Karagianni, Antreas Pavlidis, Lina S. Malakou, Christina Piperi, Evangelia Papadavid · 2022 · International Journal of Molecular Sciences
80. AKT-independent PI3-K signaling in cancer – emerging role for SGK3
    Ross D. Hannan, Bruhn, Rick Pearson, Sheppard · 2013 · Cancer Management and Research
81. Diet and Aging
    Samo Ribarič · 2012 · Oxidative Medicine and Cellular Longevity
82. Emerging evidence of a link between the polycystins and the mTOR pathways
    Alessandra Boletta · 2009 · PathoGenetics
83. Rag proteins regulate amino-acid-induced mTORC1 signalling
    Yasemin Sancak, David M. Sabatini · 2009 · Biochemical Society Transactions
84. Mammalian target of rapamycin (mTOR) as a potential therapeutic target in various diseases
    Avileen Kaur, Saurabh Sharma · 2017 · Inflammopharmacology
85. Telemedicine: medical, legal and ethical perspectives.
    Peter A. Clark, Kevin M. Capuzzi, Joseph Harrison · 2010 · PubMed
86. Metformin: The Answer to Cancer in a Flower? Current Knowledge and Future Prospects of Metformin as an Anti-Cancer Agent in Breast Cancer
    Samuel, Samson, Varghese, Elizabeth, Kubatka, Peter, Triggle, Chris, Büsselberg, Dietrich · 2019 · Biomolecules
87. Regulation of Akt during torpor in the hibernating ground squirrel, Ictidomys tridecemlineatus
    David C. McMullen, John M. Hallenbeck · 2010 · Journal of Comparative Physiology B
88. mTOR signaling networks: mechanistic insights and translational frontiers in disease therapeutics
    Hanxiao Zhang, Xia Xiao, Zhenrui Pan, Svetlana Dokudovskaya · 2025 · Signal Transduction and Targeted Therapy
89. Cell-Type-Dependent Regulation of mTORC1 by REDD1 and the Tumor Suppressors TSC1/TSC2 and LKB1 in Response to Hypoxia
    Nicholas C. Wolff, Silvia Vega-Rubín-de-Celis, Xian‐Jin Xie, Diego H. Castrillón, Wareef Kabbani, James Brugarolas · 2011 · Molecular and Cellular Biology
90. mTORC1‐ and mTORC2‐interacting proteins keep their multifunctional partners focused
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91. mTORC1 is Required for Brown Adipose Tissue Recruitment and Metabolic Adaptation to Cold
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92. Shedding new light on neurodegenerative diseases through the mammalian target of rapamycin
    Chong, Zhao Zhong, Shang, Yan Chen, Wang, Shaohui, Maiese, Kenneth · 2012 · Progress in Neurobiology
93. Transforming growth factor-β promotes prostate bone metastasis through induction of microRNA-96 and activation of the mTOR pathway
    M K Siu, Y-C Tsai, Y-S Chang, JuanJuan Yin, Florent Suau, W-Y Chen, Y-N Liu · 2014 · Oncogene
94. Peptide Combinatorial Libraries Identify TSC2 as a Death-associated Protein Kinase (DAPK) Death Domain-binding Protein and Reveal a Stimulatory Role for DAPK in mTORC1 Signaling*
    Craig Stevens, Yao-neng Lin, B. Harrison, L. Burch, R. Ridgway, O. Sansom, T. Hupp · 2009 · Journal of Biological Chemistry
95. Ubiquitin Hydrolase UCH-L1 Destabilizes mTOR Complex 1 by Antagonizing DDB1-CUL4-Mediated Ubiquitination of Raptor
    Sajjad Hussain, Andrew L. Feldman, Chittaranjan Das, Steven C. Ziesmer, Stephen Maxted Ansell, Paul J. Galardy · 2013 · Molecular and Cellular Biology
96. Considerations on mTOR regulation at serine 2448: implications for muscle metabolism studies
    Vandré C. Figueiredo, James F. Markworth, David Cameron‐Smith · 2017 · Cellular and Molecular Life Sciences
97. TGF‐β ‐induced PI3K / AKT / mTOR pathway controls myofibroblast differentiation and secretory phenotype of valvular interstitial cells through the modulation of cellular senescence in a naturally occurring in vitro canine model of myxomatous mitral valve disease
    Qiyu Tang, Greg Robert Markby, Andrew J. MacNair, Keyi Tang, Michal Tkacz, Maciej Parys, Kanchan Phadwal, Vicky Elizabeth MacRae, BRENDAN M. CORCORAN · 2023 · Cell Proliferation
98. Mammalian target of rapamycin complex 1-mediated phosphorylation of eukaryotic initiation factor 4E-binding protein 1 requires multiple protein–protein interactions for substrate recognition
    Elaine A. Dunlop, Kayleigh M. Dodd, Lyndsey A. Seymour, Andrew R. Tee · 2009 · Cellular Signalling
99. PIKKs — the solenoid nest where partners and kinases meet
    Domagoj Baretić, Roger L. Williams · 2014 · Current Opinion in Structural Biology
100. LAMP-2 deficiency leads to hippocampal dysfunction but normal clearance of neuronal substrates of chaperone-mediated autophagy in a mouse model for Danon disease
     Michelle Rothaug, Stijn Stroobants, Michaela Schweizer, Judith Peters, Friederike Zunke, Mirka Allerding, Rudi D’Hooge, Paul Säftig, Judith Blanz · 2015 · Acta Neuropathologica Communications