PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase
Sancak, Yasemin, Thoreen, Carson C., Peterson, Timothy R., Lindquist, Robert A., Kang, Seong A., Spooner, Eric, Carr, Steven A., Sabatini, David M.·2007·Molecular Cell
Cited by (1,000)
Items 101–200 of 1,000
- Signaling Pathways Involved in the Regulation of mRNA TranslationPhilippe P. Roux, Ivan Topisirović · 2018 · Molecular and Cellular Biology
- Distinct anabolic signalling responses to amino acids in C2C12 skeletal muscle cellsAtherton, Philip J., Smith, Ken, Etheridge, Timothy, Rankin, Debbie, Rennie, Michael J. · 2010 · Amino Acids
- The Proline-rich Akt Substrate of 40 kDa (PRAS40) Is a Physiological Substrate of Mammalian Target of Rapamycin Complex 1Noriko Oshiro, Rinako Takahashi, Kenichi Yoshino, Keiko Tanimura, Akio Nakashima, Satoshi Eguchi, Takafumi Miyamoto, Kenta Hara, Kenji Takehana, Joseph Avruch et al. · 2007 · Journal of Biological Chemistry
- The Roles of mTOR Complexes in Lipid MetabolismAlexandre Caron, Denis Richard, Mathieu Laplante · 2015 · Annual Review of Nutrition
- Molecular logic of mTORC1 signalling as a metabolic rheostatAlexander J. Valvezan, Brendan D. Manning · 2019 · Nature Metabolism
- mTOR and the control of whole body metabolismPazit Polak, Michael N. Hall · 2009 · Current Opinion in Cell Biology
- NF2/Merlin Is a Novel Negative Regulator of mTOR Complex 1, and Activation of mTORC1 Is Associated with Meningioma and Schwannoma GrowthMarianne F. James, Sangyeul Han, Carolyn Polizzano, Scott Randall Plotkin, Brendan D. Manning, Anat O Stemmer-Rachamimov, James F. Gusella, Vijaya Ramesh · 2009 · Molecular and Cellular Biology
- Growing knowledge of the mTOR signaling networkKezhen Huang, Diane C. Fingar · 2014 · Seminars in Cell and Developmental Biology
- Skeletal muscle tissue engineering: methods to form skeletal myotubes and their applicationsOstrovidov, Serge, Hosseini, Vahid, Ahadian, Samad, Fujie, Toshinori, Parthiban, Selvakumar Prakash, Ramalingam, Murugan, Bae, Hojae, Kaji, Hirokazu, Khademhosseini, Ali · 2014 · Tissue Engineering Part B: Reviews
- The role of mammalian target of rapamycin (mTOR) in insulin signalingYoon, Mee-Sup · 2017 · Nutrients
- PRAS40 and PRR5-Like Protein Are New mTOR Interactors that Regulate ApoptosisKathrin Thedieck, Pazit Polak, Man Lyang Kim, Klaus D. Molle, Adiel Cohen, Paul Jenö, Cécile Arrieumerlou, Michael N. Hall · 2007 · PLoS ONE
- The lysosome as a command-and-control center for cellular metabolismChun-Yan Lim, R. Zoncu · 2016 · Journal of Cell Biology
- Galectins Control mTOR in Response to Endomembrane DamageJingyue Jia, Yakubu Princely Abudu, Aurore Claude‐Taupin, Yuexi Gu, Suresh G. Kumar, Seong Won Choi, Ryan Scott Peters, Michal H. Mudd, Lee Allers, Michelle Salemi et al. · 2018 · Molecular Cell
- Ribosomal Protein S6 Phosphorylation: Four Decades of Research.O. Meyuhas · 2015 · International Review of Cell and Molecular Biology
- AMPK: Regulating Energy Balance at the Cellular and Whole Body LevelsHardie, D. Grahame, Ashford, Michael L. J. · 2014 · Physiology
- Connecting mTORC1 signaling to SREBP-1 activationInan Bakan, Mathieu Laplante · 2012 · Current Opinion in Lipidology
- The Upstream Pathway of mTOR-Mediated Autophagy in Liver DiseasesHaojie Wang, Yumei Liu, Dongmei Wang, Yaolu Xu, Ruiqi Dong, Yuxiang Yang, Qiongxia Lv, Xiaoguang Chen, Ziqiang Zhang · 2019 · Cells
- Poly(ADP-ribose) signaling in cell deathVirág, László, Robaszkiewicz, Agnieszka, Rodriguez-Vargas, Jose Manuel, Oliver, Francisco Javier · 2013 · Molecular Aspects of Medicine
- Metformin as an Anticancer AgentVancura, Ales, Bu, Pengli, Bhagwat, Madhura, Zeng, Joey, Vancurova, Ivana · 2018 · Trends in Pharmacological Sciences
- PI3K-AKT-mTOR signaling in prostate cancer progression and androgen deprivation therapy resistanceAndrewC Hsieh, Merritt P. Edlind · 2014 · Asian Journal of Andrology
- The PKB/AKT Pathway in CancerAmancio Carnero · 2009 · Current Pharmaceutical Design
- The molecular basis of nutrient sensing and signalling by mTORC1 in metabolism regulation and diseaseClaire Goul, Roberta Peruzzo, Roberto Zoncu · 2023 · Nature Reviews Molecular Cell Biology
- Role of mTOR Signaling in Tumor Cell Motility, Invasion and MetastasisShile Huang, Hongyu Zhou · 2011 · Current Protein and Peptide Science
- Signaling in Control of Cell Growth and MetabolismPatrick S. Ward, Craig B. Thompson · 2012 · Cold Spring Harbor Perspectives in Biology
- Bnip3 Mediates the Hypoxia-induced Inhibition on Mammalian Target of Rapamycin by Interacting with RhebYong Li, Yian Wang, Eunjung Kim, Peter Beemiller, Cun Yu Wang, Joel A. Swanson, Ming You, Kun‐Liang Guan · 2007 · Journal of Biological Chemistry
- The Role of mTOR Signaling as a Therapeutic Target in CancerN. V. Popova, Manfred Jücker · 2021 · International Journal of Molecular Sciences
- La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1)Bruno D. Fonseca, Chadi Zakaria, Jian-Jun Jia, Tyson Ernst Graber, Yuri V. Svitkin, Soroush Tahmasebi, Danielle Healy, Huy‐Dung Hoang, Jacob Malte Jensen, Ilo T Diao et al. · 2015 · Journal of Biological Chemistry
- ERK1/2 Phosphorylate Raptor to Promote Ras-dependent Activation of mTOR Complex 1 (mTORC1)Carriere, Audrey, Romeo, Yves, Acosta-Jaquez, Hugo A., Moreau, Julie, Bonneil, Eric, Thibault, Pierre, Fingar, Diane C., Roux, Philippe P. · 2011 · Journal of Biological Chemistry
- Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1)Laura R. Pearce, Gordon Alton, Daniel T. Richter, John C. Kath, Laura Lingardo, Justin Chapman, Catherine Hwang, Dario R. Alessi · 2010 · Biochemical Journal
- Balancing mTOR Signaling and Autophagy in the Treatment of Parkinson’s DiseaseZhou Zhu, Chuanbin Yang, Ashok Iyaswamy, Senthilkumar Krishnamoorthi, Sravan Gopalkrishnashetty Sreenivasmurthy, Jia Liu, Ziying Wang, Benjamin Chun‐Kit Tong, Ju‐Xian Song, Jiahong Lu et al. · 2019 · International Journal of Molecular Sciences
- Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesisPengda Liu, Wenjian Gan, Hiroyuki Inuzuka, Adam S. Lazorchak, Daming Gao, Omotooke Arojo, Dou Liu, Lixin Wan, Bo Zhai, Yonghao Yu et al. · 2013 · Nature Cell Biology
- Nutrient Regulation of the mTOR Complex 1 Signaling PathwaySang Gyun Kim, Gwen R. Buel, John Blenis · 2013 · Molecules and Cells
- Mammalian target of rapamycin complex 1: Signalling inputs, substrates and feedback mechanismsElaine A. Dunlop, Andrew R. Tee · 2009 · Cellular Signalling
- AKT/FOXO Signaling Enforces Reversible Differentiation Blockade in Myeloid LeukemiasS. Sykes, Steven W. Lane, L. Bullinger, D. Kalaitzidis, R. Yusuf, B. Saez, F. Ferraro, F. Mercier, Harshabad Singh, K. Brumme et al. · 2011 · Cell
- mTOR signaling in skeletal development and diseaseJianquan Chen, Fanxin Long · 2018 · Bone Research
- The serine/threonine kinase ULK1 is a target of multiple phosphorylation eventsMarkus Bach, Mark Larance, David Ernest James, Georg Ramm · 2011 · Biochemical Journal
- Emerging role of autophagy in kidney function, diseases and agingTobias Bruno Huber, Charles L. Edelstein, Björn Hartleben, Ken Inoki, Man Jiang, Daisuke Koya, Shinji Kume, Wilfred Lieberthal, Nicolas Pallet, Alejandro Quiroga et al. · 2012 · Autophagy
- Testosterone regulation of Akt/mTORC1/FoxO3a signaling in skeletal muscleJames P. White, Song Gao, Melissa Puppa, Shuichi Sato, Stephen L. Welle, James A. Carson · 2012 · Molecular and Cellular Endocrinology
- Targeting autophagy-related protein kinases for potential therapeutic purposeHonggang Xiang, Jifa Zhang, Congcong Lin, Lan Zhang, Bo Liu, Liang Ouyang · 2019 · Acta Pharmaceutica Sinica B
- mTOR Drives Its Own Activation via SCFβTrCP-Dependent Degradation of the mTOR Inhibitor DEPTORDaming Gao, Hiroyuki Inuzuka, Meng-Kwang Marcus Tan, Hidefumi Fukushima, Jason W. Locasale, Pengda Liu, Lixin Wan, Bo Zhai, Y. Rebecca Chin, Shavali Shaik et al. · 2011 · Molecular Cell
- A comprehensive map of the mTOR signaling networkÉtienne Caron, Samik Ghosh, Yukiko Matsuoka, Dariel Ashton‐Beaucage, Marc Therrien, Sébastien Lemieux, Claude Perreault, Philippe P. Roux, Hiroaki Kitano · 2010 · Molecular Systems Biology
- Targeting tumor cell metabolism with statinsJames W. Clendening, Linda Z. Penn · 2012 · Oncogene
- Interconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy developmentMayur Vilas Jain, Anna Paczulla, Thomas C. Klonisch, Florence N. Dimgba, Sahana Bhima Rao, Karin B. Roberg, Frank Schweizer, Claudia Lengerke, Padideh Davoodpour, Vivek Reddy Palicharla et al. · 2013 · Journal of Cellular and Molecular Medicine
- PRAS40 Is a Target for Mammalian Target of Rapamycin Complex 1 and Is Required for Signaling Downstream of This ComplexBruno D. Fonseca, Ewan M. Smith, Vivian H.-Y. Lee, Carol MacKintosh, Christopher G. Proud · 2007 · Journal of Biological Chemistry
- The role of mTOR signaling in Alzheimer diseaseSalvatore Oddo · 2012 · Frontiers in Bioscience-Scholar
- Amino Acid Signaling in TOR ActivationJoungmok Kim, Kun‐Liang Guan · 2011 · Annual Review of Biochemistry
- AKT (v-akt murine thymoma viral oncogene homolog 1) and N-Ras (neuroblastoma ras viral oncogene homolog) coactivation in the mouse liver promotes rapid carcinogenesis by way of mTOR (mammalian target of rapamycin complex 1), FOXM1 (forkhead box M1)/SKP2, and c-Myc pathwaysCoral Ho, Chunmei Wang, Sandra Mattu, Giulia Destefanis, Sara Ladu, Salvatore Delogu, Julia Armbruster, Lingling Fan, Susie A. Lee, Lijie Jiang et al. · 2011 · Hepatology
- Autophagy signal transduction by ATG proteins: from hierarchies to networksSebastian Wesselborg, Björn Stork · 2015 · Cellular and Molecular Life Sciences
- Myocardial AKT: The Omnipresent NexusMark Alan Sussman, Mirko Völkers, Kimberlee M. Fischer, Brandi Bailey, Christopher T. Cottage, Shabana Din, Natalie A. Gude, Daniele Avitabile, Roberto Alvarez, Balaji Sundararaman et al. · 2011 · Physiological Reviews
- Insulin Resistance and Diabetes Mellitus in Alzheimer’s DiseaseJesús Burillo, Patricia Marqués, Beatriz Jiménez, Carlos González-Blanco, Manuel Benito, Carlos Guillén · 2021 · Cells
- mTOR Ser-2481 Autophosphorylation Monitors mTORC-specific Catalytic Activity and Clarifies Rapamycin Mechanism of ActionGhada A. Soliman, Hugo A. Acosta-Jaquez, Elaine A. Dunlop, Bilgen Ekim Üstünel, Nicole E. Maj, Andrew R. Tee, Diane C. Fingar · 2009 · Journal of Biological Chemistry
- MicroRNA-21 Orchestrates High Glucose-induced Signals to TOR Complex 1, Resulting in Renal Cell Pathology in DiabetesNirmalya Dey, Falguni Das, Meenalakshmi M. Mariappan, Chandi Charan Mandal, Nandini Ghosh‐Choudhury, Balakuntalam S. Kasinath, Goutam Ghosh Choudhury · 2011 · Journal of Biological Chemistry
- ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate bindingDunlop, Elaine A., Hunt, David K., Acosta-Jaquez, Hugo A., Fingar, Diane C., Tee, Andrew R. · 2011 · Autophagy
- PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα InhibitionPau Castel, Haley Ellis, Ružica Bago, Eneda Toska, Pedram Razavi, F. Javier Carmona, Srinivasaraghavan Kannan, Chandra Shekhar Verma, Maura N. Dickler, Sarat Chandarlapaty et al. · 2016 · Cancer Cell
- Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPKXiaona Liu, Rishi Raj Chhipa, Shabnam Pooya, Matthew D. Wortman, Sara Yachyshin, Lionel M.L. Chow, Ashish Kumar, Xuan Zhou, Ying Hao Sun, Brian Quinn et al. · 2014 · Proceedings of the National Academy of Sciences
- Temsirolimus Activates Autophagy and Ameliorates Cardiomyopathy Caused by Lamin A/C Gene MutationJason C. Choi, Antoine Muchir, Wei Wu, Shinichi Iwata, Shunichi Homma, John Morrow, Howard J. Worman · 2012 · Science Translational Medicine
- Metabolic Stress Controls mTORC1 Lysosomal Localization and Dimerization by Regulating the TTT-RUVBL1/2 ComplexKim, Sang Gyun, Hoffman, Gregory R., Poulogiannis, George, Buel, Gwen R., Jang, Young Jin, Lee, Ki Won, Kim, Bo-Yeon, Erikson, Raymond L., Cantley, Lewis C., Choo, Andrew Y. et al. · 2013 · Molecular Cell
- Single amino-acid changes that confer constitutive activation of mTOR are discovered in human cancerTatsuhiro Sato, Akio Nakashima, Lea Guo, Kimberly Coffman, Fuyuhiko Tamanoi · 2010 · Oncogene
- Chapter 1 Physiological Roles of Ribosomal Protein S6: One of Its KindOded Meyuhas · 2008 · International review of cytology
- Role of PI3K-AKT-mTOR Pathway as a Pro-Survival Signaling and Resistance-Mediating Mechanism to Therapy of Prostate CancerThanakorn Pungsrinont, Julia Kallenbach, Aria Baniahmad · 2021 · International Journal of Molecular Sciences
- PIKKing on PKB: regulation of PKB activity by phosphorylationLana Bozulic, Brian A. Hemmings · 2009 · Current Opinion in Cell Biology
- mTOR and Beclin1: Two key autophagy‐related molecules and their roles in myocardial ischemia/reperfusion injuryBinhao Shi, Mengqing Ma, Yitian Zheng, Yanyan Pan, Xianhe Lin · 2019 · Journal of Cellular Physiology
- Research progress of mTOR inhibitorsYifan Chen, Xiao‐Ping Zhou · 2020 · European Journal of Medicinal Chemistry
- TOR regulation of AGC kinases in yeast and mammalsEstela Jacinto, Anja Lorberg · 2008 · Biochemical Journal
- mTOR-Dependent Cell Survival MechanismsClarey Hung, Luisa García-Haro, C. A. Sparks, David A. Guertin · 2012 · Cold Spring Harbor Perspectives in Biology
- The Translational Regulation in mTOR PathwayMiaomiao Yang, Yanming Lu, Weilan Piao, Hua Jin · 2022 · Biomolecules
- Curcumin Disrupts the Mammalian Target of Rapamycin-Raptor ComplexChristopher S. Beevers, Long Chen, Lei Liu, Yan Luo, Nicholas J. G. Webster, Shile Huang · 2009 · Cancer Research
- Identification of MicroRNA-124-3p as a Putative Epigenetic Signature of Major Depressive DisorderRoy, Bhaskar, Dunbar, Michael, Shelton, Richard C, Dwivedi, Yogesh · 2017 · Neuropsychopharmacology
- Specific Activation of mTORC1 by Rheb G-protein in Vitro Involves Enhanced Recruitment of Its Substrate ProteinSato, Tatsuhiro, Nakashima, Akio, Guo, Lea, Tamanoi, Fuyuhiko · 2009 · Journal of Biological Chemistry
- Defining the underlying defect in insulin action in type 2 diabetesThiago M. Batista, Nida Haider, C. Ronald Kahn · 2021 · Diabetologia
- Apoptotic Pathways and Alzheimer’s Disease: Probing Therapeutic PotentialVivek Sharma, Thakur Gurjeet Singh, Shareen Singh, Nikhil Garg, Sonia Dhiman · 2021 · Neurochemical Research
- Regulation of mRNA Translation by Signaling PathwaysIvan Topisirović, I. Topisirovic · 2012 · Cold Spring Harbor Perspectives in Biology
- Early activation of mTORC1 signalling in response to mechanical overload is independent of phosphoinositide 3‐kinase/Akt signallingMitsunori Miyazaki, John Joseph McCarthy, Mark J. Fedele, Karyn Ann Esser · 2011 · The Journal of Physiology
- mTOR signaling in stem and progenitor cellsDelong Meng, Anderson R. Frank, Jenna L. Jewell · 2018 · Development
- Regulation of mTOR Complex 1 (mTORC1) by Raptor Ser863 and Multisite PhosphorylationKathryn G. Foster, Hugo A. Acosta-Jaquez, Yves Roméo, Bilgen Ekim Üstünel, Ghada A. Soliman, Audrey Carriere, Philippe P. Roux, Bryan A. Ballif, Diane C. Fingar · 2009 · Journal of Biological Chemistry
- mTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic InterventionsMehvish Showkat, Mushtaq Ahmad Beigh, Khurshid Iqbal Andrabi · 2014 · Molecular Biology International
- New Insights into mTOR Signaling: mTORC2 and BeyondDario R. Alessi, Laura R. Pearce, Juan Manuel García‐Martínez · 2009 · Science Signaling
- Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activityBernadette Carroll, D. Maetzel, O. Maddocks, Gisela Otten, M. Ratcliff, Graham R. Smith, E. Dunlop, J. Passos, O. R. Davies, R. Jaenisch et al. · 2016 · eLife
- Critical Role for Hypothalamic mTOR Activity in Energy BalanceHiroyuki Mori, Ken Inoki, Heike Münzberg, Darren M. Opland, Miro Faouzi, Eneida C. Villanueva, Tsuneo Ikenoue, David J. Kwiatkowski, Ormond A. MacDougald, Martin Grosvenor Myers et al. · 2009 · Cell Metabolism
- Regulation of Proline-rich Akt Substrate of 40 kDa (PRAS40) Function by Mammalian Target of Rapamycin Complex 1 (mTORC1)-mediated PhosphorylationLifu Wang, Thurl E. Harris, John C. Lawrence · 2008 · Journal of Biological Chemistry
- Glycolytic Flux Signals to mTOR through Glyceraldehyde-3-Phosphate Dehydrogenase-Mediated Regulation of RhebMi Nam Lee, Sang Hoon Ha, Jaeyoon John Kim, Ara Koh, Chang Sup Lee, Jung Hwan Kim, Hyeona Jeon, Do‐Hyung Kim, Pann‐Ghill Suh, Sung Ho Ryu · 2009 · Molecular and Cellular Biology
- Organ Size Control by Hippo and TOR PathwaysKaren Tumaneng, Ryan Charles Russell, Kun‐Liang Guan · 2012 · Current Biology
- The Role of the Mammalian Target of Rapamycin (mTOR) in Pulmonary FibrosisJessica Lawrence, Richard Seonghun Nho · 2018 · International Journal of Molecular Sciences
- The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathwayCarbonneau, Mélissa, M. Gagné, Laurence, Lalonde, Marie-Eve, Germain, Marie-Anne, Motorina, Alena, Guiot, Marie-Christine, Secco, Blandine, Vincent, Emma E., Tumber, Anthony, Hulea, Laura et al. · 2016 · Nature Communications
- Bridges between mitochondrial oxidative stress, ER stress and mTOR signaling in pancreatic β cellsJing Wang, Xin Yang, Jingjing Zhang · 2016 · Cellular Signalling
- Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidneyLaura R. Pearce, Eeva M. Sommer, Kei Sakamoto, Stephan Wullschleger, Dario R. Alessi · 2011 · Biochemical Journal
- The insulin receptor substrate (IRS) proteinsLeslie M. Shaw · 2011 · Cell Cycle
- Simvastatin induces derepression of PTEN expression via NFκB to inhibit breast cancer cell growthNayana Ghosh-Choudhury, Chandi Charan Mandal, Nandini Ghosh-Choudhury, Goutam Ghosh Choudhury · 2010 · Cellular Signalling
- mTORC2: The other mTOR in autophagy regulationJosué Ballesteros‐Álvarez, Julie Kay Andersen · 2021 · Aging Cell
- DAP1, a Novel Substrate of mTOR, Negatively Regulates AutophagyItay Koren, Eran Reem, Adi Kimchi · 2010 · Current Biology
- Role of PRAS40 in Akt and mTOR signaling in health and diseaseClaudia Wiza, Emmani B. M. Nascimento, D. Margriet Ouwens · 2012 · American Journal of Physiology-Endocrinology and Metabolism
- Resveratrol Inhibits mTOR Signaling by Promoting the Interaction between mTOR and DEPTORMeilian Liu, Sarah Ann Wilk, Anping Wang, Lijun Zhou, Rui-Hong Wang, Wataru Ogawa, Chu‐Xia Deng, Lily Dong, Feng Liu · 2010 · Journal of Biological Chemistry
- Regulation of Body Size and Growth ControlM. Texada, Takashi Koyama, K. Rewitz · 2020 · Genetics
- mTORC1 and Nutrient Homeostasis: The Central Role of the LysosomeY. Rabanal-Ruiz, V. Korolchuk · 2018 · International Journal of Molecular Sciences
- Naturally Secreted Amyloid-β Increases Mammalian Target of Rapamycin (mTOR) Activity via a PRAS40-mediated MechanismAntonella Caccamo, Mónica A. Maldonado, Smita Majumder, David X. Medina, Walter W. Holbein, Andrea Magrì, Salvatore Oddo · 2011 · Journal of Biological Chemistry
- The expanding role of mTOR in cancer cell growth and proliferationMarie Cargnello, Joseph Tcherkezian, Philippe P. Roux · 2015 · Mutagenesis
- Regulation of reproduction and longevity by nutrient-sensing pathwaysNicole M. Templeman, Coleen T. Murphy · 2017 · The Journal of Cell Biology
- Site-Specific mTOR Phosphorylation Promotes mTORC1-Mediated Signaling and Cell GrowthHugo A. Acosta-Jaquez, Jennifer A. Keller, Kathryn G. Foster, Bilgen Ekim Üstünel, Ghada A. Soliman, Edward P. Feener, Bryan A. Ballif, Diane C. Fingar · 2009 · Molecular and Cellular Biology
- mTOR kinase leads to PTEN-loss-induced cellular senescence by phosphorylating p53Jung, Seung Hee, Hwang, Hyun Jung, Kang, Donghee, Park, Hyun A., Lee, Hyung Chul, Jeong, Daecheol, Lee, Keunwook, Park, Heon Joo, Ko, Young-Gyu, Lee, Jae-Seon · 2019 · Oncogene
- The central moTOR of metabolismJudith Simcox, Dudley W. Lamming · 2022 · Developmental Cell