PRAS40 Is an Insulin-Regulated Inhibitor of the mTORC1 Protein Kinase
Sancak, Yasemin, Thoreen, Carson C., Peterson, Timothy R., Lindquist, Robert A., Kang, Seong A., Spooner, Eric, Carr, Steven A., Sabatini, David M.·2007·Molecular Cell
Cited by (999)
Items 901–999 of 999
- Integration of network toxicology, machine learning and single-cell sequencing reveals the effects of soil pollutants on prostate cancerZhiyu Liu, Yuqi Li, Juan Wang, Yang Zeng, Qilong Wu, Xinyao Zhu, Tao Zhou, Qingfu Deng · 2025 · Ecotoxicology and Environmental Safety
- Differential control of ageing and lifespan by isoforms and splice variants across the mTOR networkPatricia Razquin Navas, Kathrin Thedieck · 2017 · Essays in Biochemistry
- High PRAS40 mRNA expression and its role in prognosis of clear cell renal cell carcinomaJintuo Zhou, Yanting Zhu, Ying Liu, Peiguang Niu, Huajiao Chen, Jie Deng, Daohua Shi · 2020 · Translational Andrology and Urology
- Translational Aspects of the Mammalian Target of Rapamycin Complexes in Diabetic NephropathyAlaa Abou Daher, Sahar Alkhansa, William S. Azar, Rim W. Rafeh, Hilda E. Ghadieh, Assaad Antoine Eid · 2021 · Antioxidants and Redox Signaling
- Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1Amelia K. Luciano, Ekaterina D. Korobkina, Scott P. Lyons, John D. Haley, Shelagh M. Fluharty, Su Myung Jung, Arminja Nadine Kettenbach, David A. Guertin · 2022 · Journal of Biological Chemistry
- Improvement of mTORC1-driven overproduction of apoB-containing triacylglyceride-rich lipoproteins by short-chain fatty acids, 4-phenylbutyric acid and (R)-α-lipoic acid, in human hepatocellular carcinoma cellsJoseph L. Roberts, Bo He, Anjeza Erickson, Régis F. Moreau · 2015 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
- Montelukast enhances cytocidal effects of carfilzomib in multiple myeloma by inhibiting mTOR pathwayJia Tong, Qing Yu, Wenbin Xu, Wenjun Yu, Chao Wu, Yingli Wu, Hua Yan · 2018 · Cancer Biology & Therapy
- The endolysosomal adaptor PLEKHM1 is a direct target for both mTOR and MAPK pathwaysAndrea Gubaš, Christina Karantanou, Doris Popovic, Georg Tascher, Marina E. Hoffmann, Anna Platzek, Nina Dawe, Ivan Đikić, Daniela S. Krause, David G. McEwan · 2021 · FEBS Letters
- Impaired Hypothalamic mTOR Activation in the Adult Rat Offspring Born to Mothers Fed a Low-Protein DietO. Guzmán-Quevedo, R. da Silva Aragão, G. Pérez-García, R. Matos, A. de Sá Braga Oliveira, R. D. de Castro, F. Bolaños-Jiménez · 2013 · PLoS ONE
- TORC1 autonomously controls its spatial partitioning via the Rag GTPase tether Tco89Raffaele Nicastro, Marie‐Pierre Gulli, Marco Caligaris, Malika Jaquenoud, Ladislav Dokládal, Josephine Alba, Farida Tripodi, Benjamin Pillet, Melanie Brunner, Michael Stumpe et al. · 2025 · Cell Reports
- Tsc2, a positional candidate gene underlying a quantitative trait locus for hepatic steatosisChen‐Yu Wang, Donald S. Stapleton, Kathryn L. Schueler, Mary E. Rabaglia, Angie Tebon Oler, Mark P. Keller, Christina M. Kendziorski, Karl W. Broman, Brian S. Yandell, Eric E. Schadt et al. · 2012 · Journal of Lipid Research
- Phosphoproteomics of cAMP signaling of Bordetella adenylate cyclase toxin in mouse dendritic cellsJakub Novák, Ivo Fabrik, Irena Linhartová, Marek Link, Ondřej Černý, Jiří Stulík, Peter Šebo · 2017 · Scientific Reports
- Lys05 – A Promising Autophagy Inhibitor in the Radiosensitization Battle: Phosphoproteomic PerspectiveMartin Ondrej, Lucie Čecháková, Ivo Fabrik, Jana Klimentová, Aleš Tichý · 2020 · Cancer Genomics & Proteomics
- Insulin resistance without elevated mammalian target of rapamycin complex 1 activity in muscles of mice fed a high-fat dietThomas Reynolds, Nicholas Cinquino, Marcus Anthony, Charles B. Phelps, Eli Zachary Berk · 2009 · Journal of Applied Physiology
- Energy-Sensing Pathways in Ischemia: The Counterbalance Between AMPK and mTORCÁngel Enrique Céspedes-Rubio, Mario Villa, Irene Benito‐Cuesta, María José Pérez-Álvarez, Lara Ordóñez‐Gutiérrez, Francisco G. Wandosell · 2019 · Current Pharmaceutical Design
- Small molecule H89 renders the phosphorylation of S6K1 and AKT resistant to mTOR inhibitorsChase H. Melick, Jenna L. Jewell · 2020 · Biochemical Journal
- Target of rapamycin (TOR) gene is vital for whitefly survival and reproductionHeena Puri, Vikas Jindal · 2021 · Journal of Biosciences
- Regulation of Apoptosis and Autophagy During Anoxia in the Freshwater Crayfish, Faxonius virilisSarah A. Breedon, Aakriti Gupta, Kenneth B. Storey · 2022 · Marine Biotechnology
- The Akt Forkhead Box O Transcription Factor Axis Regulates Human Cytomegalovirus ReplicationHongbo Zhang, Anthony J. Domma, Felicia D. Goodrum, Nathaniel J. Moorman, Jeremy P. Kamil · 2022 · mBio
- The role of mechanistic target of rapamycin in maintenance of glomerular epithelial cellsYao Yao, Ken Inoki · 2015 · Current Opinion in Nephrology & Hypertension
- The Apoptosis Regulator 14-3-3η and Its Potential as a Therapeutic Target in Pituitary OncocytomaSida Zhao, Bin Li, Chuzhong Li, Hua Gao, Yazhou Miao, Yue He, Hongyun Wang, Lei Gong, Dan Li, Yazhuo Zhang et al. · 2019 · Frontiers in Endocrinology
- Crosstalk between the mTOR pathway and primary cilia in human diseasesPhilipp P. Prosseda, Svenja Dannewitz Prosseda, Matthew Tran, Paloma B. Liton, Yang Sun · 2023 · Current topics in developmental biology/Current Topics in Developmental Biology
- Rapamycin improves the survival of epilepsy model cells by blocking phosphorylation of mTOR base on computer simulations and cellular experimentsKezhou Li, Jun‐Feng Cao, Yunli Gong, Xiong Li, Mei Wu, Yue Qi, Xiran Ying, Dengxin Liu, Xuntai Ma, Xiao Zhang · 2024 · Neurochemistry International
- Role of PIM Kinase Inhibitor in the Treatment of Alzheimer’s DiseaseShreyasi Meur, Swarupananda Mukherjee, Souvik Roy, Dipanjan Karati · 2024 · Molecular Neurobiology
- NDRG1 and its family members: More than just metastasis suppressor proteins and targets of thiosemicarbazonesMahan Gholam Azad, Tiffany M. Russell, Xuanling Gu, Xiao Zhao, Věra Richardson, Tharushi P. Wijesinghe, Golap Babu, Xinnong Guo, Büşra Kaya, Mahendiran Dharmasivam et al. · 2025 · Journal of Biological Chemistry
- Comprehensive Characterization of a Novel E3-Related Gene Signature With Implications in Prognosis and Immunotherapy of Low-Grade GliomasShichuan Tan, Ryan Spear, Juan Zhao, Xiulian Sun, Pin Wang · 2022 · Frontiers in Genetics
- Dietary β‐sitosterol supplementation enhanced intestinal immune function of large yellow croaker ( Larimichthys crocea ) infected with Aeromonas hydrophilaYan Song, Zhiyuan Lu, Xiaofang Zhang, Jing Xu, Miao Gong, Lingting Meng, Zhiyuan Gong, Bin Zheng · 2022 · Aquaculture Research
- The role of Raptor in lymphocytes differentiation and functionJianing Tang, Lu Yang, Fei Guan, Heather Miller, Niels Olsen Saraiva Câmara, Louisa Katherine James, Kamel Benlagha, Masato Kubo, Steffen Heegaard, Pamela P. W. Lee et al. · 2023 · Frontiers in Immunology
- PRAS40 alleviates neurotoxic prion peptide‐induced apoptosis via mTOR‐AKT signalingWei Yang, Lifeng Yang, Zhiqi Song, Syed Zahid Ali Shah, Yongyong Cui, Chaosi Li, Huafen Zhao, Hong‐Li Gao, Xiangmei Zhou, De‐Ming Zhao · 2017 · CNS Neuroscience & Therapeutics
- CDK 4/6 Inhibition Overcomes Acquired and Inherent Resistance to PI3Kα Inhibition in Pre-Clinical Models of Head and Neck Squamous Cell CarcinomaEric Remer, Mai Badarni, Elad Hikri, Avraham Dayan, Lirit Levi, Aron Popovtzer, Muhammed Iraqi, Angel Porgador, Ben‐Zion Joshua, Gideon Y. Bachar et al. · 2020 · Journal of Clinical Medicine
- Deciphering the enigmatic crosstalk between prostate cancer and Alzheimer's disease: A current update on molecular mechanisms and combination therapyNitesh Kumar Poddar, Disha Agarwal, Yamini Agrawal, Yasanandana Supunsiri Wijayasinghe, Arunima Mukherjee, Shahanavaj Khan · 2022 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- The skeletal muscle fiber periphery: A nexus of mTOR-related anabolismCassidy T. Tinline‐Goodfellow, Matthew J. Lees, Nathan W. Hodson · 2022 · Sports Medicine and Health Science
- The EIF4EBP3 translational repressor is a marker of CDC73 tumor suppressor haploinsufficiency in a parathyroid cancer syndromeZhang Jh, Erica M. Seigneur, M Pandey, Anna Loshakov, Pradeep Kumar Dagur, Patricia S. Connelly, Lily Y. Koo, Leelamma M. Panicker, William F. Simonds · 2012 · Cell Death and Disease
- Mechanisms and Control of Protein Translation in the KidneyValérie Schaeffer, Christine K. Abrass · 2009 · American Journal of Nephrology
- Role of PKB/Akt in Liver DiseasesElena Zhuravleva, Oliver Tschopp, Brian A. Hemmings · 2009 · Springer eBooks
- Influence of Age on Skeletal Muscle Hypertrophy and Atrophy Signaling: Established Paradigms and Unexpected LinksEunjoo Hwang Lee, Ronald L. Neppl · 2021 · Genes
- Early loss of mammalian target of rapamycin complex 1 (mTORC1) signalling and reduction in cell size during dominant-negative suppression of hepatic nuclear factor 1-α (HNF1A) function in INS-1 insulinoma cellsAngela M. Farrelly, H Wobser, Caroline Bonner, Sergio Anguissola, Markus Rehm, Caoimhín G. Concannon, Jochen H.M. Prehn, Maria M. Byrne · 2008 · Diabetologia
- The indispensable role of the RNA helicase DDX5 in tumorigenesis induced by the myeloproliferative neoplasm-associated JAK2V617F mutantKengo Takeda, Kenji Tago, Megumi Funakoshi‐Tago · 2022 · Cellular Signalling
- TAS0612, a Novel RSK, AKT, and S6K Inhibitor, Exhibits Antitumor Effects in Preclinical Tumor ModelsK. Ichikawa, Satoshi Ito, Emi Kato, Naomi Abe, Takumitsu Machida, Junya Iwasaki, Gotaro Tanaka, Hikari Araki, Kentaro Wakayama, Hideki Jona et al. · 2023 · Molecular Cancer Therapeutics
- Recent insights into the pathophysiology of mTOR pathway dysregulationDeborah A. Altomare, Sarah B. Gitto · 2015 · Research and Reports in Biology
- Role of mTOR in the regulation of skeletal muscle metabolismNatalia D. Golberg, Anastasiya M. Druzhevskaya, Viktor A. Rogozkin, Ildus I. Ahmetov · 2014 · Human Physiology
- Evolution of TOR and Translation ControlBruno D. Fonseca, Tyson Ernst Graber, Huy‐Dung Hoang, Asier González, Alexander A. Soukas, Greco Hernández, Tommy Alain, Stephanie Louise Swift, Ronit Weisman, Christian Meyer et al. · 2016 · Springer eBooks
- WNK1 signalling regulates amino acid transport and mTORC1 activity to sustain acute myeloid leukaemia growthShunlei Duan, Karl Agger, Jan‐Erik Messling, Koutarou Nishimura, Xuerui Han, Isabel Peña‐Rømer, Pavel V. Shliaha, Helene Damhofer, Max E. Douglas, Manas Kohli et al. · 2025 · Nature Communications
- How is the AKT/mTOR pathway involved in cell migration and invasion?JINGYAO XU, SHUANGLI HAO, KAIYUE HAN, WANXI YANG, Hong Xin Deng · 2023 · Biocell
- The effects of PKI-402 on breast tumor models’ radiosensitivity via dual inhibition of PI3K/mTORRöya Gasımlı, Çağla Kayabaşı, Besra Özmen Yelken, Aycan Aşık, Fatma Söğütlü, Çağlar Çelebi, Sunde Yılmaz Süslüer, Serra Kamer, Çıgır Biray Avci, Ayfer Haydaroğlu et al. · 2023 · International Journal of Radiation Biology
- The Target of Rapamycin: Structure and FunctionsChang‐Chih Wu, Po‐Chien Chou, Estela Jacinto · 2012 · InTech eBooks
- Evaluating the mTOR Pathway in Physiological and Pharmacological SettingsSungki Hong, Ken Inoki · 2016 · Methods in enzymology on CD-ROM/Methods in enzymology
- S6K2 Promises an Important Therapeutic Potential for CancerNurettin İlter Sever, Sevilay Cengiz · 2018 · Future Oncology
- Cytotoxicity of oleanane type triterpene from leaf extract of Pterospermum acerifolium (in vitro) and theoretical investigation of inhibitory signaling pathwayMohd Rehan, Shafiullah, Sultanat · 2020 · Chinese Herbal Medicines
- The TORC1 phosphoproteome in C. elegans reveals roles in transcription and autophagyAileen K. Sewell, Zachary C. Poss, Christopher C. Ebmeier, Jeremy R. Jacobsen, William M. Old, Min Han · 2022 · iScience
- Fathoming the Role of mTOR in Diabetes Mellitus and its ComplicationsFaheem Faheem, Shanthi Sivasubrmanian · 2022 · Current Molecular Pharmacology
- Translational Control by Amino Acids and EnergyKathrin Thedieck, Michael N. Hall · 2010 · Elsevier eBooks
- Current Phase II clinical data for ridaforolimus in cancerAnna Spreafico, Helen J MacKay · 2013 · Expert Opinion on Investigational Drugs
- The mTOR Signaling Pathway in Neurodegenerative DiseasesArnaud Francois, Julie Vérité, Agnès Rioux Bilan, Thierry Janet, Frédéric Calon, Bernard Fauconneau, Marc Paccalin, Guylène Page · 2016 · Elsevier eBooks
- Identification of the Novel Interacting Partners of the Mammalian Target of Rapamycin Complex 1 in Human CCRF-CEM and HEK293 CellsHazır Rahman, Muhammad Qasim, Michael Oellerich, Abdul Rahman Asif · 2014 · International Journal of Molecular Sciences
- MARCH1 negatively regulates TBK1-mTOR signaling pathway by ubiquitinating TBK1Xiao Li, Kai Cheng, Meng-Di Shang, Yong Yang, Bin Hu, Xi Wang, Xiao-Dan Wei, Yanchun Han, Xiaogang Zhang, Meng-Hua Dong et al. · 2024 · BMC Cancer
- Structural and mechanistic basis of mTORC2 activation of protein kinase AKT/PKBNam Ky Chu, Nhat T. T. Le, Ouada Nebie, Sammi Yang · 2026 · Biochemical Journal
- Research Translation and Personalized MedicineJames Brugarolas · 2012 · Springer eBooks
- Proline-rich Akt substrate of 40-kDa contains a nuclear export signalClaudia Wiza, Emmani B. M. Nascimento, Margot M. L. Linssen, Françoise Carlotti, Daniella Herzfeld de Wiza, Gerard C.M. van der Zon, J. Antonie Maassen, Michaëla Diamant, Bruno Guigas, D. Margriet Ouwens · 2013 · Cellular Signalling
- The TSC1–TSC2 Complex2010 · The Enzymes
- Cellular metabolism and lysosomal mTOR signalingIsrael C. Nnah, Khoosheh Khayati, Radek Dobrowolski · 2015 · Cell death in therapy
- A clinically feasible multiplex proteomic immunoassay as a novel functional diagnostic for pancreatic ductal adenocarcinomaKian‐Huat Lim, Emma J. Langley, Feng Gao, Jingqin Rosy Luo, Lin Li, Gary E. Meyer, Phillip Kim, Sharat Singh, Vladamir M. Kushnir, Dayna S. Early et al. · 2017 · Oncotarget
- Formal Modeling of mTOR Associated Biological Regulatory Network Reveals Novel Therapeutic Strategy for the Treatment of CancerZurah Bibi, J. Ahmad, Amnah Siddiqa, R. Paracha, Tariq Saeed, Amjad Ali, H. A. Janjua, S. Ullah, E. Ben Abdallah, Olivier F. Roux · 2017 · Frontiers in Physiology
- Herbal cake-partitioned moxibustion inhibits colonic autophagy in Crohn’s disease via signaling involving distinct classes of phosphatidylinositol 3-kinasesShi-Yuan Wang, Jimeng Zhao, Ci-Li Zhou, Handan Zheng, Yan Huang, Min Zhao, Zhiying Zhang, Luyi Wu, Huangan Wu, Huirong Liu · 2020 · World Journal of Gastroenterology
- The mTOR Pathway and AgingKatherine H. Schreiber, Monique N. O’Leary, Brian Keith Kennedy · 2015 · Elsevier eBooks
- Nutrition, Nitrogen Requirements, Exercise and Chemotherapy-Induced Toxicity in Cancer Patients. A puzzle of Contrasting Truths?Vincenzo Flati, Giovanni Corsetti, Evasio Pasini, Anna Rufo, Claudia Romano, Francesco Saverio Dioguardi · 2015 · Anti-Cancer Agents in Medicinal Chemistry
- Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegenerationAlicia R. Lane, Noah E. Scher, Shatabdi Bhattacharjee, Stephanie A. Zlatic, Anne M. Roberts, Avanti Gokhale, Kaela S. Singleton, Duc Minh Duong, Mike McKenna, William L. Liu et al. · 2025 · Molecular Biology of the Cell
- MTORC2 is a physiological hydrophobic motif kinase of S6 Kinase 1Sheikh Tahir Majeed, Rabiya Majeed, Aijaz A. Malik, Muhammad Afzal Zargar, Khurshid Iqbal Andrabi · 2023 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- mTOR signaling pathway and mTOR inhibitors in the treatment of cancerMehmet Küçüköner · 2013 · Dicle Medical Journal / Dicle Tip Dergisi
- Current Coverage of the mTOR Pathway by Next-Generation Sequencing Oncology PanelsRita Seeboeck, Victoria Sarne, Johannes Haybaeck · 2019 · International Journal of Molecular Sciences
- mTOR–mLST8 interaction: hot spot identification through quantum biochemistry calculationsFrancisco Lucas Santos de Oliveira, Jaqueline Vieira Carletti, Francisca Fernanda Nunes Azevedo, Francisca Joseli Freitas de Sousa, E. W. S. Caetano, V. N. Freire, Geancarlo Zanatta · 2020 · New Journal of Chemistry
- Potential of mTOR inhibitors as therapeutic agents in hematological malignanciesKamalesh Kumar Sankhala, Francis Joseph Giles · 2009 · Expert Review of Hematology
- AMPKDaniel Garcia, Maria M. Mihaylova, Reuben J. Shaw · 2020 · Wiley eBooks
- Cerebellar phenotypes in germline PTEN mutation carriersDonatella Gambini, Stefano Ferrero, Gaetano Bulfamante, Luigi Pisani, Massimo Corbo, Elisabetta Kuhn · 2024 · Neuropathology and Applied Neurobiology
- White Adipocyte Stem Cell Expansion Through Infant Formula Feeding: New Insights into Epigenetic Programming Explaining the Early Protein Hypothesis of ObesityBodo Clemens Melnik, Ralf Weiskirchen, Swen Malte John, Wolfgang Stremmel, Claus Leitzmann, Sabine Weiskirchen, Gerd Schmitz · 2025 · International Journal of Molecular Sciences
- LPS诱导的肺纤维细胞PTEN基因表达和Akt磷酸化蛋白表达的研究Mao-lin HUANG, Zhen‐Dong Yang, Lu-lu GONG, Ning Cui · 2014 · 国际中西医结合杂志
- Somatic Variants in SVIL in Cerebral AneurysmsPui Man Rosalind Lai, Jee‐Yeon Ryu, Sang‐Cheol Park, Bradley A. Gross, Lawrence D. Dickinson, Sarajune Dagen, Mohammad Ali Aziz‐Sultan, Alan S. Boulos, Daniel Louis Barrow, H. Hunt Batjer et al. · 2022 · Neurology Genetics
- TGF-β phospho antibody array identifies altered SMAD2, PI3K/AKT/SMAD, and RAC signaling contribute to the pathogenesis of myxomatous mitral valve diseaseAndrew J. McNair, Greg Robert Markby, Qiyu Tang, Vicky Elizabeth MacRae, BRENDAN M. CORCORAN · 2023 · Frontiers in Veterinary Science
- Exercise, mTOR Activation, and Potential Impacts on the Liver in RodentsGiuliano Moreto Onaka, Marianna Rabelo de Carvalho, Patricia Kubalaki Onaka, Claudiane Maria Barbosa, Paula Felippe Martinez, Silvio Assis de Oliveira-Junior · 2024 · Biology
- TOR ComplexesVittoria Zinzalla, Thomas Wayne Sturgill, Michael N. Hall · 2010 · The Enzymes
- TGFβ signaling-induced miRNA participates in autophagic regulation by targeting PRAS40 in mesenchymal subtype of glioblastomaYingbin Xie, Luyue Chen, Junhu Zhou, Qixue Wang, Chao Yang, Can Xu, Xiangyu Fan, Yanli Tan, Yanan Wang, Chunsheng Kang et al. · 2020 · Cancer Biology and Medicine
- Regulation of TOR Signaling in MammalsDudley W. Lamming, David M. Sabatini · 2010 · The Enzymes
- Phytochemical modulation of mTOR signaling: emerging nanotechnology-driven therapeutics for rheumatoid arthritis managementDeepa S. Mandlik, Prapti Adgaonkar, Satish K. Mandlik · 2025 · Inflammopharmacology
- Research progress on the role of acupuncture in Alzheimer's disease based on the PI3K/AKT/mTOR signaling pathwaySiqi Zhang, Xue Fan Gu, Miao Zhang, Ning Ding, Jing Yang, Tianyi Wang · 2026 · Journal of Alzheimer s Disease
- The rapamycin sTORy: 50-year journey from Easter Island to the frontiers of biology and medicineXia Xiao, Svetlana Dokudovskaya · 2026 · Trends in Biochemical Sciences
- Effects of heroin self-administration and forced withdrawal on the expression of genes related to the mTOR network in the basolateral complex of the amygdala of male Lewis ratsMarcos Ucha, David Roura‐Martínez, Raquel Santos‐Toscano, Roberto Capellán, Emilio Ambrosio, Alejandro Higuera‐Matas · 2022 · Psychopharmacology
- Adropin increases with swimming exercise and exerts a protective effect on the brain of aged ratsHande Parlak, Ayşe Özkan, Osman Sinen, Mehmet Bülbül, Mutay Aslan, Ayşel Ağar · 2022 · Experimental Gerontology
- Stage-specific regulation of undifferentiated spermatogonia by AKT1S1-mediated AKT-mTORC1 signaling during mouse spermatogenesisLele Yang, Jinyue Liao, Hongying Huang, TL Lee, Huayu Qi · 2024 · Developmental Biology
- Deciphering the intricate role of mTOR signaling and autophagy in Parkinson's disease and therapeutic prospectLakshmi Narayanan, Dithu Thekkekkara, Sreenivasulu Naidu Kondaveeti, Amrita Babu, Banerjee Aniruddha Sailen, Saravana Babu Chidambaram, Santhepete Nanjundaiah Manjula · 2024 · Journal of Applied Pharmaceutical Science
- FOXC1 transcriptionally suppresses ABHD5 to inhibit the progression of renal cell carcinoma through AMPK/mTOR pathwayJianfa Li, Shuangchen Chen, Jing Xiao, Jiayuan Ji, Chenchen Huang, Shu Ge · 2024 · Cell Biology and Toxicology
- High-density lipoprotein protects normotensive and hypertensive rats against ischemia-reperfusion injury through differential regulation of mTORC1 and mTORC2 signalingReham Al-Othman, Aishah Al‐Jarallah, Fawzi A. Babiker · 2024 · Frontiers in Pharmacology
- Mechanisms of Resistance to PI3K and AKT InhibitorsPau Castel, Maurizio Scaltriti · 2018 · Resistance to targeted anti-cancer therapeutics
- Understanding intrinsic survival and regenerative pathways through in vivo and in vitro studies: implications for optic nerve regenerationToshiyuki Oshitari · 2021 · Expert Review of Ophthalmology
- Regulation of mTOR complexes in long-lived growth hormone receptor knockout and Snell dwarf miceXiaofang Shi, S. Joseph Endicott, Richard A. Miller · 2022 · Aging
- DEPTOR loss impairs brown adipocyte development in vitro but has limited impacts in miceCharles Colas, Mathilde Mouchiroud, Manal Al Dow, Alona Kolnohuz, Yves Gélinas, Alexandre Caron, Mathieu Laplante · 2022 · Molecular Metabolism
- mTORC1 Signaling and HypoxiaJames Brugarolas · 2009 · Humana Press eBooks
- Actions and interactions of AMPK with insulin, the peroxisomal-proliferator activated receptors and sirtuinsMark J. Holness, Peter H. Sugden, Marta Paulino Silvestre, Mary C. Sugden · 2012 · Expert Review of Endocrinology & Metabolism
- PI(3)K–Akt–mTOR pathway as a potential therapeutic target in neuroendocrine tumorsKathrin Zitzmann, George Vlotides, Burkhard Göke, Christoph Josef Auernhammer · 2008 · Expert Review of Endocrinology & Metabolism
- Understanding the complex role of mTORC as an intracellular critical mediator of whole-body metabolism in anorexia nervosa: A mini review.2021 · Acta bio-medica dell'Ateneo parmense/Acta biomedica