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ROS-Mediated p53 Induction of Lpin1 Regulates Fatty Acid Oxidation in Response to Nutritional Stress
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“p53 also activates malonyl-CoA decarboxylase (MCD), PANK1, and CPT1C to accelerate fatty acid oxidation.93–95”
From p53: from understanding its structure to advances in therapeutic targeting (2026) · cites this paper as [95]
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Citations
Cites
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
Bakkenist, C. J., & Kastan, M. B. (2003) · Nature · doi:10.1038/nature01368 · Cited by 3,466
Blinded by the Light: The Growing Complexity of p53
Vousden, K. H., & Prives, C. (2009) · Cell · doi:10.1016/j.cell.2009.04.037 · Cited by 3,163
p53 Regulates Mitochondrial Respiration
Matoba, S., Kang, J.-G., Patino, W. D., Wragg, A., Boehm, M., Gavrilova, O., Hurley, P. J., Bunz, F., & Hwang, P. M. (2006) · Science · doi:10.1126/science.1126863 · Cited by 1,650
Topology of superoxide production from different sites in the mitochondrial electron transport chain
St-Pierre, J., Buckingham, J. A., Roebuck, S. J., & Brand, M. D. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m207217200 · Cited by 1,545
Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression
Lecker, S. H., Jagoe, R. T., Gilbert, A., Gomes, M., Baracos, V., Bailey, J., Price, S. R., Mitch, W. E., & Goldberg, A. L. (2004) · The FASEB Journal · doi:10.1096/fj.03-0610com · Cited by 1,539 · cited 1×
“Importantly, Lpin1 mRNA levels were shown to be elevated in muscle in a fastinginduced cachexia model (Lecker et al., 2004), and Lpin1 was shown to be induced in the livers of fasting mice (Finck et al.”
BackgroundThe expanding universe of p53 targets
Menendez, D., Inga, A., & Resnick, M. A. (2009) · Nature Reviews Cancer · doi:10.1038/nrc2730 · Cited by 568
Noncanonical DNA Motifs as Transactivation Targets by Wild Type and Mutant p53
Jordan, J. J., Menendez, D., Inga, A., Nourredine, M., Bell, D., & Resnick, M. A. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.1000104 · Cited by 103
Research works printed but not linked: 37
- Alexander, 2010, ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS, Proc. Natl. Acad. Sci. USA, 107, 4153, 10.1073/pnas.0913860107 · DOI · Paper page
- Anderson, 2001, Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage, Mol. Cell. Biol., 21, 1719, 10.1128/MCB.21.5.1719-1729.2001 · DOI · Paper page
- Armata, 2010, Requirement of the ATM/p53 tumor suppressor pathway for glucose homeostasis, Mol. Cell. Biol., 30, 5787, 10.1128/MCB.00347-10 · DOI
- Balaban, 2005, Mitochondria, oxidants, and aging, Cell, 120, 483, 10.1016/j.cell.2005.02.001 · DOI · Paper page
- Bencokova, 2009, ATM activation and signaling under hypoxic conditions, Mol. Cell. Biol., 29, 526, 10.1128/MCB.01301-08 · DOI · Paper page
- Bensaad, 2007, p53: new roles in metabolism, Trends Cell Biol., 17, 286, 10.1016/j.tcb.2007.04.004 · DOI · Paper page
- Bensaad, 2006, TIGAR, a p53-inducible regulator of glycolysis and apoptosis, Cell, 126, 107, 10.1016/j.cell.2006.05.036 · DOI · Paper page
- Budanov, 2004, Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD, Science, 304, 596, 10.1126/science.1095569 · DOI · Paper page
- el-Deiry, 1993, WAF1, a potential mediator of p53 tumor suppression, Cell, 75, 817, 10.1016/0092-8674(93)90500-P · DOI · Paper page
- Fediuc, 2006, Regulation of AMP-activated protein kinase and acetyl-CoA carboxylase phosphorylation by palmitate in skeletal muscle cells, J. Lipid Res., 47, 412, 10.1194/jlr.M500438-JLR200 · DOI
- Feng, 2005, The coordinate regulation of the p53 and mTOR pathways in cells, Proc. Natl. Acad. Sci. USA, 102, 8204, 10.1073/pnas.0502857102 · DOI · Paper page
- Feng, 2007, The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways, Cancer Res., 67, 3043, 10.1158/0008-5472.CAN-06-4149 · DOI · Paper page
- Finck, 2006, Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway, Cell Metab., 4, 199, 10.1016/j.cmet.2006.08.005 · DOI · Paper page
- Fu, 2008, Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation, PLoS ONE, 3, e2009, 10.1371/journal.pone.0002009 · DOI · Paper page
- Guo, 2010, ATM activation by oxidative stress, Science, 330, 517, 10.1126/science.1192912 · DOI · Paper page
- Han, 2006, The Saccharomyces cerevisiae Lipin homolog is a Mg2+-dependent phosphatidate phosphatase enzyme, J. Biol. Chem., 281, 9210, 10.1074/jbc.M600425200 · DOI · Paper page
- Hemann, 2003, An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo, Nat. Genet., 33, 396, 10.1038/ng1091 · DOI · Paper page
- Ho, 2005, p53-Dependent transcriptional repression of c-myc is required for G1 cell cycle arrest, Mol. Cell. Biol., 25, 7423, 10.1128/MCB.25.17.7423-7431.2005 · DOI · Paper page
- Hu, 2010, Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function, Proc. Natl. Acad. Sci. USA, 107, 7455, 10.1073/pnas.1001006107 · DOI · Paper page
- Hue, 2009, The Randle cycle revisited: a new head for an old hat, Am. J. Physiol. Endocrinol. Metab., 297, E578, 10.1152/ajpendo.00093.2009 · DOI · Paper page
- Ide, 2009, GAMT, a p53-inducible modulator of apoptosis, is critical for the adaptive response to nutrient stress, Mol. Cell, 36, 379, 10.1016/j.molcel.2009.09.031 · DOI
- Johnson, 1993, Growth suppression of Friend virus-transformed erythroleukemia cells by p53 protein is accompanied by hemoglobin production and is sensitive to erythropoietin, Mol. Cell. Biol., 13, 1456, 10.1128/MCB.13.3.1456 · doi:10.1128/mcb.13.3.1456
- Jones, 2005, AMP-activated protein kinase induces a p53-dependent metabolic checkpoint, Mol. Cell, 18, 283, 10.1016/j.molcel.2005.03.027 · DOI · Paper page
- Koo, 2005, The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism, Nature, 437, 1109, 10.1038/nature03967 · DOI · Paper page
- Paull, 2000, A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage, Curr. Biol., 10, 886, 10.1016/S0960-9822(00)00610-2 · DOI · Paper page
- Péterfy, 2001, Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin, Nat. Genet., 27, 121, 10.1038/83685 · DOI · Paper page
- Phan, 2005, Lipin, a lipodystrophy and obesity gene, Cell Metab., 1, 73, 10.1016/j.cmet.2004.12.002 · DOI · Paper page
- Phan, 2004, Lipin expression preceding peroxisome proliferator-activated receptor-γ is critical for adipogenesis in vivo and in vitro, J. Biol. Chem., 279, 29558, 10.1074/jbc.M403506200 · DOI · Paper page
- Rappold, 2001, Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways, J. Cell Biol., 153, 613, 10.1083/jcb.153.3.613 · DOI · Paper page
- Reue, 2008, The lipin protein family: dual roles in lipid biosynthesis and gene expression, FEBS Lett., 582, 90, 10.1016/j.febslet.2007.11.014 · DOI · Paper page
- Ryu, 2009, TORC2 regulates hepatic insulin signaling via a mammalian phosphatidic acid phosphatase, LIPIN1, Cell Metab., 9, 240, 10.1016/j.cmet.2009.01.007 · DOI
- Schultz, 2000, p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks, J. Cell Biol., 151, 1381, 10.1083/jcb.151.7.1381 · DOI · Paper page
- Seifert, 2010, Electron transport chain-dependent and -independent mechanisms of mitochondrial H2O2 emission during long-chain fatty acid oxidation, J. Biol. Chem., 285, 5748, 10.1074/jbc.M109.026203 · DOI · Paper page
- Stambolic, 2001, Regulation of PTEN transcription by p53, Mol. Cell, 8, 317, 10.1016/S1097-2765(01)00323-9 · DOI · Paper page
- Suzuki, 2010, Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species, Proc. Natl. Acad. Sci. USA, 107, 7461, 10.1073/pnas.1002459107 · DOI · Paper page
- Vander Heiden, 2009, Understanding the Warburg effect: the metabolic requirements of cell proliferation, Science, 324, 1029, 10.1126/science.1160809 · DOI · Paper page
- Wheaton, 2010, BTG2 antagonizes Pin1 in response to mitogens and telomere disruption during replicative senescence, Aging Cell, 9, 747, 10.1111/j.1474-9726.2010.00601.x · DOI
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Ward, P. S., & Thompson, C. B. (2012) · Cancer Cell · doi:10.1016/j.ccr.2012.02.014 · Cited by 3,233
P53 in survival, death and metabolic health: a lifeguard with a licence to kill.
Kruiswijk, F., Labuschagne, C. F., & Vousden, K. H. (2015) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm4007 · Cited by 1,080
Census and evaluation of p53 target genes
Fischer, M. (2017) · Oncogene · doi:10.1038/onc.2016.502 · Cited by 971
The interplay between cell signalling and the mevalonate pathway in cancer
Mullen, P. J., Yu, R., Longo, J., Archer, M. C., & Penn, L. Z. (2016) · Nature Reviews Cancer · doi:10.1038/nrc.2016.76 · Cited by 699
Moon, J.-S., Nakahira, K., Chung, K.-P., DeNicola, G. M., Koo, M. J., Pabón, M. A., Rooney, K. T., Yoon, J.-H., Ryter, S. W., Stout-Delgado, H., et al. (2016) · Nature Medicine · doi:10.1038/nm.4153 · Cited by 291
Retracted
Metadata
- Authors
- Assaily, W., Rubinger, D. A., Wheaton, K., Lin, Y., Ma, W., Xuan, W., Brown-Endres, L., Tsuchihara, K., Mak, T. W., & Benchimol, S.
- Venue
- Molecular Cell
- Publisher
- Elsevier BV
- Published
- 2011-11
- Volume
- 44
- Issue
- 3
- Pages
- 491-501
- ISSN
- 1097-2765 (ISSN-L)
- OpenAlex
- W2088621072
- Cited by
- 192
- References
- 7
- FWCI
- 4.83
- Type
- journal article
- Language
- en
- Open access
- bronze
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 624 d)
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- CoChat. (2026). Citation check: ROS-Mediated p53 Induction of Lpin1 Regulates Fatty Acid Oxidation in Response to Nutritional Stress. https://app.cochat.ai/papers/10.1016/j.molcel.2011.08.038
- The paper
- Assaily, W., Rubinger, D. A., Wheaton, K., Lin, Y., Ma, W., Xuan, W., Brown-Endres, L., Tsuchihara, K., Mak, T. W., & Benchimol, S. (2011). ROS-Mediated p53 Induction of Lpin1 Regulates Fatty Acid Oxidation in Response to Nutritional Stress. Molecular Cell. https://doi.org/10.1016/j.molcel.2011.08.038
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