The mitochondrial basis of aging

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Items 101–200 of 1,000

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   Chak Kwong Cheng, Jiang‐Yun Luo, Chi Wai Lau, Zhen‐Yu Chen, Xiao Yu Tian, Yü Huang · 2019 · British Journal of Pharmacology
2. Mitochondrial Diagnostics: A Multiplexed Assay Platform for Comprehensive Assessment of Mitochondrial Energy Fluxes
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3. Mitochondrial Dysfunction and Ovarian Aging
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4. The Muscle-Brain Axis and Neurodegenerative Diseases: The Key Role of Mitochondria in Exercise-Induced Neuroprotection
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5. The mitochondrial epitranscriptome: the roles of RNA modifications in mitochondrial translation and human disease
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6. The Role of Nrf2 in the Antioxidant Cellular Response to Medical Ozone Exposure
   Mirco Galiè, Viviana Covi, Gabriele Tabaracci, Manuela Malatesta · 2019 · International Journal of Molecular Sciences
7. Heterochromatin: an epigenetic point of view in aging
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8. Reduced Circulating Insulin Enhances Insulin Sensitivity in Old Mice and Extends Lifespan
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9. Emerging Anti-Aging Strategies - Scientific Basis and Efficacy
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10. MitophAging: Mitophagy in Aging and Disease
    Daniela Bakula, Morten Scheibye‐Knudsen · 2020 · Frontiers in Cell and Developmental Biology
11. Age- and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body disease
    Hou, Xu, Fiesel, Fabienne C., Truban, Dominika, Castanedes Casey, Monica, Lin, Wen-lang, Soto, Alexandra I., Tacik, Pawel, Rousseau, Linda G., Diehl, Nancy N., Heckman, Michael G. et al. · 2018 · Autophagy
12. Mitochondrial Function and Cell Size: An Allometric Relationship
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13. Circulating Mitochondrial DNA at the Crossroads of Mitochondrial Dysfunction and Inflammation During Aging and Muscle Wasting Disorders
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15. Genistein mitigates senescence of bone marrow mesenchymal stem cells via ERRα-mediated mitochondrial biogenesis and mitophagy in ovariectomized rats
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16. Placental Ageing in Adverse Pregnancy Outcomes: Telomere Shortening, Cell Senescence, and Mitochondrial Dysfunction
    Samprikta Manna, Cathal McCarthy, Fergus P. McCarthy · 2019 · Oxidative Medicine and Cellular Longevity
17. The Mitochondria–Endoplasmic Reticulum Contacts and Their Critical Role in Aging and Age-Associated Diseases
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18. Mitochondria, Estrogen and Female Brain Aging
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19. FOXG1 promotes aging inner ear hair cell survival through activation of the autophagy pathway
    Zuhong He, Ming Li, Qiaojun Fang, Fu-ling Liao, Shengyu Zou, Xia Wu, Haiying Sun, Xueyan Zhao, Yujuan Hu, Xiaoxiang Xu et al. · 2021 · Autophagy
20. Upregulation of the Autophagy Adaptor p62/SQSTM1 Prolongs Health and Lifespan in Middle-Aged Drosophila
    Aparicio, Ricardo, Rana, Anil, Walker, David W. · 2019 · Cell Reports
21. Systemic isradipine treatment diminishes calcium-dependent mitochondrial oxidant stress
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22. Mitochondrial quality control in cartilage damage and osteoarthritis: new insights and potential therapeutic targets
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23. Dysregulation of mitochondrial dynamics proteins are a targetable feature of human tumors
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24. Contribution of the Nrf2 Pathway on Oxidative Damage and Mitochondrial Failure in Parkinson and Alzheimer’s Disease
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25. Late-onset Alzheimer’s disease is associated with inherent changes in bioenergetics profiles
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26. UBQLN1 mediates sorafenib resistance through regulating mitochondrial biogenesis and ROS homeostasis by targeting PGC1β in hepatocellular carcinoma
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27. Multifaceted deregulation of gene expression and protein synthesis with age
    Aleksandra S. Anisimova, Mark Meerson, Maxim V. Gerashchenko, Ivan V. Kulakovskiy, Sergey E. Dmitriev, Vadim N. Gladyshev · 2020 · Proceedings of the National Academy of Sciences
28. Protective Role of Melatonin and Its Metabolites in Skin Aging
    Georgeta Bocheva, Radomir M. Slominski, Zorica Janjetović, Tae‐Kang Kim, Markus Böhm, Kerstin Steinbrink, Russel Joseph Reiter, Konrad Kleszczyński, Andrzej T. Slominski · 2022 · International Journal of Molecular Sciences
29. Peroxisomes in Immune Response and Inflammation
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30. Mitochondrial Dysfunction in Adipocytes as a Primary Cause of Adipose Tissue Inflammation
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31. Hallmarks and detection techniques of cellular senescence and cellular ageing in immune cells
    Dingxi Zhou, Mariana Borsa, Anna Katharina Simon · 2021 · Aging Cell
32. Mouse models of ageing and their relevance to disease
    Kõks, Sulev, Dogan, Soner, Tuna, Bilge Guvenc, González-Navarro, Herminia, Potter, Paul, Vandenbroucke, Roosmarijn E. · 2016 · Mechanisms of Ageing and Development
33. Brain cells derived from Alzheimer’s disease patients have multiple specific innate abnormalities in energy metabolism
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34. Tissue‐ and Condition‐Specific Isoforms of Mammalian Cytochrome c Oxidase Subunits: From Function to Human Disease
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35. Mouse Models to Disentangle the Hallmarks of Human Aging
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36. Cellular Senescence: Pathogenic Mechanisms in Lung Fibrosis
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37. Frailty in surgical patients
    Simon J. G. Richards, Frank Frizelle, John A. Geddes, Tim Eglinton, Mark B. Hampton · 2018 · International Journal of Colorectal Disease
38. Neuropsychology of aging
    Ronald A. Cohen, Michael Marsiske, Glenn E. Smith · 2019 · Handbook of clinical neurology
39. Astaxanthin as a Novel Mitochondrial Regulator: A New Aspect of Carotenoids, beyond Antioxidants
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40. Psychological stress during childhood and adolescence and its association with inflammation across the lifespan: A critical review and meta-analysis.
    Jessica J. Chiang, Phoebe H. Lam, Edith Chen, Gregory E. Miller · 2022 · Psychological Bulletin
41. Sex-Specific Gene Expression and Life Span Regulation
    Tower, John · 2017 · Trends in Endocrinology & Metabolism
42. Regulation of longevity by FGF21: interaction between energy metabolism and stress responses
    Salminen, Antero, Kaarniranta, Kai, Kauppinen, Anu · 2017 · Ageing Research Reviews
43. Mitochondrial Heterogeneity
    Juvid Aryaman, Iain G. Johnston, Nick S. Jones · 2019 · Frontiers in Genetics
44. Mitochondrial Regulation of Microglial Immunometabolism in Alzheimer’s Disease
    Fairley, Lauren H., Wong, Jia Hui, Barron, Anna M. · 2021 · Frontiers in Immunology
45. Mitochondrial dysfunctions, oxidative stress and neuroinflammation as therapeutic targets for neurodegenerative diseases: An update on current advances and impediments
    Rehman, Muneeb U., Sehar, Nouroz, Dar, Nawab John, Khan, Andleeb, Arafah, Azher, Rashid, Summya, Rashid, Shahzada Mudasir, Ganaie, Majid Ahmad · 2023 · Neuroscience & Biobehavioral Reviews
46. Adverse Childhood Experiences Run Deep: Toxic Early Life Stress, Telomeres, and Mitochondrial DNA Copy Number, the Biological Markers of Cumulative Stress
    Kathryn K. Ridout, Mariam B. Khan, Samuel J. Ridout · 2018 · BioEssays
47. From molecular promise to preclinical results: HDAC inhibitors in the race for healthy aging drugs
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48. Known unknowns of cardiolipin signaling: The best is yet to come
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49. RAB7 activity is required for the regulation of mitophagy in oocyte meiosis and oocyte quality control during ovarian aging
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50. Sample multiplexing for targeted pathway proteomics in aging mice
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51. Adult mesenchymal stem cell ageing interplays with depressed mitochondrial Ndufs6
    Yuelin Zhang, Liyan Guo, Shuo Han, Ling Chen, Cheng Li, Zhao Zhang, Yimei Hong, Xiaoxian Zhang, Xiaoya Zhou, Dan Jiang et al. · 2020 · Cell Death and Disease
52. Mitochondria transplantation between living cells
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53. Structural basis of mitochondrial transcription
    Hillen, Hauke S., Temiakov, Dmitry, Cramer, Patrick · 2018 · Nature Structural & Molecular Biology
54. Aspirin Recapitulates Features of Caloric Restriction
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55. Astroglial asthenia and loss of function, rather than reactivity, contribute to the ageing of the brain
    Alexei Verkhratsky, Marcus Augusto‐Oliveira, Augustas Pivoriūnas, Alexander Popov, Alexey Brazhe, Alexey V. Semyanov · 2020 · Pflügers Archiv - European Journal of Physiology
56. SGLT2 Inhibitors as Calorie Restriction Mimetics: Insights on Longevity Pathways and Age-Related Diseases
    Caroline Wei Shan Hoong, Marvin Wei Jie Chua · 2021 · Endocrinology
57. Characterization of mitochondrial DNA quantity and quality in the human aged and Alzheimer’s disease brain
    Hans‐Ulrich Klein, Caroline Trumpff, Hyun‐Sik Yang, Annie Lee, Martin A. Picard, David Alan Bennett, Philip L. De Jager · 2021 · Molecular Neurodegeneration
58. The impact of mitochondrial impairments on sperm function and male fertility: a systematic review
    Minoo Vahedi Raad, Amir Masoud Firouzabadi, Maryam Tofighi Niaki, Ralf Henkel, Farzaneh Fesahat · 2024 · Reproductive Biology and Endocrinology
59. The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2
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60. A Comprehensive Overview of the Complex Role of Oxidative Stress in Aging, The Contributing Environmental Stressors and Emerging Antioxidant Therapeutic Interventions
    Evripides Iakovou, Malamati Kourti · 2022 · Frontiers in Aging Neuroscience
61. Targeting the Mitochondrial Permeability Transition Pore to Prevent Age‐Associated Cell Damage and Neurodegeneration
    Andrew C. Kent, Khairat Bahgat Youssef El Baradie, Mark W. Hamrick · 2021 · Oxidative Medicine and Cellular Longevity
62. The metabolic characteristics and changes of chondrocytes in vivo and in vitro in osteoarthritis
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63. Mitochondrial dysfunction and its association with age-related disorders
    Indumathi Somasundaram, Samatha M. Jain, Marcel Blot‐Chabaud, Surajit Pathak, Antara Banerjee, Sonali Jalan Rawat, Neeta Raj Sharma, Asim K. Duttaroy · 2024 · Frontiers in Physiology
64. Nutritional Status as a Mediator of Fatigue and Its Underlying Mechanisms in Older People
    Domenico Azzolino, Beatrice Arosio, Emanuele Marzetti, Riccardo Calvani, Matteo Cesari · 2020 · Nutrients
65. Obstructive Sleep Apnea and Hallmarks of Aging
    Laetitia S. Gaspar, Ana Rita Álvaro, Joaquim Jorge Moita, Cláudia Cavadas · 2017 · Trends in Molecular Medicine
66. Quality Control in Neurons: Mitophagy and Other Selective Autophagy Mechanisms
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67. Mitochondria dysfunction in CD8+ T cells as an important contributing factor for cancer development and a potential target for cancer treatment: a review
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68. Oxidative Stress in Reproduction: A Mitochondrial Perspective
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69. Loss of Metabolic Plasticity Underlies Metformin Toxicity in Aged Caenorhabditis Elegans
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70. Mitochondria targeting by environmental stressors: Implications for redox cellular signaling
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71. The Aging Mitochondria
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72. The deteriorating soma and the indispensable germline: gamete senescence and offspring fitness
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73. PUMILIO hyperactivity drives premature aging of Norad-deficient mice
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74. Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction
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75. Cellular senescence in gastrointestinal diseases: from pathogenesis to therapeutics
    Frey, Nina, Venturelli, Sascha, Zender, Lars, Bitzer, Michael · 2018 · Nature Reviews Gastroenterology & Hepatology
76. Axonal Degeneration in AD: The Contribution of Aβ and Tau
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77. Protein Signatures of Centenarians and Their Offspring Suggest Centenarians Age Slower than Other Humans
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78. Telomerase and telomeres in aging theory and chronographic aging theory (Review)
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79. MFN2 contributes to metabolic disorders and inflammation in the aging of rat chondrocytes and osteoarthritis
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80. Mitochondrial Complex 1 Activity Measured by Spectrophotometry Is Reduced across All Brain Regions in Ageing and More Specifically in Neurodegeneration
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81. Phase separation of Nur77 mediates celastrol-induced mitophagy by promoting the liquidity of p62/SQSTM1 condensates
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82. The mitochondrial permeability transition: Nexus of aging, disease and longevity
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83. Mitochondrial Dysfunction in the Transition from NASH to HCC
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84. Mitochondrial calcium uptake declines during aging and is directly activated by oleuropein to boost energy metabolism and skeletal muscle performance
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85. Targeting the proteostasis network in Huntington’s disease
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86. Carnitine palmitoyltransferase 1C regulates cancer cell senescence through mitochondria-associated metabolic reprograming
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87. Mitochondria Are Important Determinants of the Aging of Seeds
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88. Single-cell epigenome analysis reveals age-associated decay of heterochromatin domains in excitatory neurons in the mouse brain
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89. Mechanisms, pathophysiological roles and methods for analyzing mitophagy – recent insights
    Jessica A. R. Williams, Wen‐Xing Ding · 2017 · Biological Chemistry
90. Astrocytes autophagy in aging and neurodegenerative disorders
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91. High-content fluorescence imaging with the metabolic flux assay reveals insights into mitochondrial properties and functions
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92. Healthy brain aging: Interplay between reactive species, inflammation and energy supply
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93. Systemic effects of mitochondrial stress
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94. The Novel Role of Mitochondrial Citrate Synthase and Citrate in the Pathophysiology of Alzheimer’s Disease
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95. The role of SIRT1 in skeletal muscle function and repair of older mice
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96. Multi-modal profiling of peripheral blood cells across the human lifespan reveals distinct immune cell signatures of aging and longevity
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97. AMPK and HIF signaling pathways regulate both longevity and cancer growth: the good news and the bad news about survival mechanisms
    Antero Salminen, Kai Kaarniranta, Anu Kauppinen · 2016 · Biogerontology
98. Mitochondrial Trafficking and Processing of Telomerase RNA TERC.
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99. Assessment of mitophagy in mt‐Keima Drosophila revealed an essential role of the PINK1‐Parkin pathway in mitophagy induction in vivo
    Young Yeon Kim, J. Um, Jeong-Hyun Yoon, Hyunjin Kim, Da-Ye Lee, Y. Lee, H. Jee, Young Mi Kim, J. S. Jang, Yoon-Gu Jang et al. · 2019 · The FASEB Journal
100. CD38 deficiency alleviates Ang II-induced vascular remodeling by inhibiting small extracellular vesicle-mediated vascular smooth muscle cell senescence in mice
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