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Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver

Hinrichs, Arne, Kessler, Barbara, Kurome, Mayuko, Blutke, Andreas, Kemter, Elisabeth, Bernau, Maren, Scholz, Armin M., Rathkolb, Birgit, Renner, Simone, Bultmann, Sebastian, Leonhardt, Heinrich, de Angelis, Martin Hrabĕ, Nagashima, Hiroshi, Hoeflich, Andreas, Blum, Werner F., Bidlingmaier, Martin, Wanke, Rüdiger, Dahlhoff, Maik, Wolf, Eckhard·2018·Molecular Metabolism
DOI 10.1016/j.molmet.2018.03.006PMC PMC6001387
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  • Elimination of growth hormone receptor gene expression could reduce organ sizes but comes with other undesired biological consequences.

    “Although elimination of growth hormone receptor gene expression could reduce organ sizes2,3, it comes with other undesired biological consequences7.”

    From Design and testing of a humanized porcine donor for xenotransplantation (2023) · cites this paper as [7]

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Research works printed but not linked: 87

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Metadata

Authors
Hinrichs, A., Kessler, B., Kurome, M., Blutke, A., Kemter, E., Bernau, M., Scholz, A. M., Rathkolb, B., Renner, S., Bultmann, S., Leonhardt, H., de Angelis, M. H., Nagashima, H., Hoeflich, A., Blum, W. F., Bidlingmaier, M., Wanke, R., Dahlhoff, M., & Wolf, E.
Venue
Molecular Metabolism
Publisher
Elsevier BV
Published
2018-05
Volume
11
Pages
113-128
ISSN
2212-8778
DOI
10.1016/j.molmet.2018.03.006
PMC
PMC6001387
Cited by
96
References
6
Language
en
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