Masterclass: Hypermobility and hypermobility related disorders
Open accessAbstract
Introduction Hypermobile joints display a range of movement that is considered excessive, taking into consideration the age, gender and ethnic background of the individual. Joint hypermobility may present in a single joint, a few joints or in multiple joints and may be congenital or acquired with training, disease or injury. Hypermobile joints may be asymptomatic or may be associated with pain, fatigue, multisystemic complaints and significant disability. Furthermore, joint hypermobility may be a sign of an underlying hereditary disorder of connective tissue.Purpose This masterclass aims to provides a state-of-the-art review of the aetiology, epidemiology, clinical presentation, assessment and management of joint hypermobility and hypermobility related disorders using an evidence based and biopsychosocial approach. The new framework for classifying the spectrum of joint hypermobility disorders along with new diagnostic criteria for the hypermobile Ehlers Danlos syndrome, published by an international consortium of clinical experts and researchers in 2017 is integrated into the paper.Implications for practice People with joint hypermobility related disorders present to healthcare professionals with a wide range of symptoms which extend beyond the musculoskeletal system. Early recognition and treatment are key to effective management. A biopsychosocial and patient empowerment approach to functional restoration is recommended.
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Fatigue occurs in up to 84% of patients with HSDs.
“Fatigue (up to 84%)”
From Hypermobility spectrum disorders: A review (2023) · cites this paper as [45]
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Phenotypic manifestations of connective tissue dysplasia in individuals with joint hypermobility
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Self-citationComorbilidades en los síndromes de Ehlers-Danlos y los trastornos del espectro hipermóvil
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Bewegungskontrolle der Halswirbelsäule – neues Verständnis eines alten Konzepts
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- Authors
- Simmonds, J. V.
- Affiliations
- The Wellington Hospital (GB)
- Corresponding author
- Simmonds, J.V.
- ORCID
- Simmonds, J.V.
- Venue
- Musculoskeletal Science and Practice
- Publisher
- Elsevier BV
- Published
- 2022-02
- Volume
- 57
- Pages
- 102465
- ISSN
- 2468-7812 (ISSN-L)
- OpenAlex
- W3206552555
- Cited by
- 21
- References
- 95
- Citations by year
- 2026: 3 · 2025: 6 · 2024: 4 · 2023: 6 · 2022: 2
- FWCI
- 1.69
- Type
- journal article
- Language
- en
- Open access
- green
- discovery.ucl.ac.uk
- Licence
- Locations
- Musculoskeletal Science and Practice (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Connective tissue disorders research
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Myofascial pain diagnosis and treatment
- Keywords
- joint hypermobility, hypermobile Ehlers-Danlos syndrome, connective tissue diseases, etiology, clinical features, assessment, biopsychosocial model, patient empowerment, functional restoration, diagnostic criteria
- MeSH terms
- Ehlers-Danlos Syndrome, Humans, Joint Instability, Movement, Pain, Patient Participation
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