Cited by 21Connective tissue disorders researchMusculoskeletal pain and rehabilitationMyofascial pain diagnosis and treatment

Masterclass: Hypermobility and hypermobility related disorders

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Simmonds, J.V.·2022·Musculoskeletal Science and Practice

Abstract

Introduction Hypermobile joints display a range of movement that is considered excessive, taking into consideration the age, gender and ethnic background of the individual. Joint hypermobility may present in a single joint, a few joints or in multiple joints and may be congenital or acquired with training, disease or injury. Hypermobile joints may be asymptomatic or may be associated with pain, fatigue, multisystemic complaints and significant disability. Furthermore, joint hypermobility may be a sign of an underlying hereditary disorder of connective tissue.Purpose This masterclass aims to provides a state-of-the-art review of the aetiology, epidemiology, clinical presentation, assessment and management of joint hypermobility and hypermobility related disorders using an evidence based and biopsychosocial approach. The new framework for classifying the spectrum of joint hypermobility disorders along with new diagnostic criteria for the hypermobile Ehlers Danlos syndrome, published by an international consortium of clinical experts and researchers in 2017 is integrated into the paper.Implications for practice People with joint hypermobility related disorders present to healthcare professionals with a wide range of symptoms which extend beyond the musculoskeletal system. Early recognition and treatment are key to effective management. A biopsychosocial and patient empowerment approach to functional restoration is recommended.

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  1. DE WANDELE ET AL. 2021. Exercise Guidelines for Postural Orthostatic Tachycardia Syndrome Postural Tachycardia Syndrome: A Concise and Practical Guide to Management and Associated Conditions Editors: Gall, Nicholas, Kavi, Lesley, Lobo, Melvin (Eds.), Pages 207-215.

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Authors
Simmonds, J. V.
Affiliations
The Wellington Hospital (GB)
Corresponding author
Simmonds, J.V.
Venue
Musculoskeletal Science and Practice
Publisher
Elsevier BV
Published
2022-02
Volume
57
Pages
102465
ISSN
2468-7812 (ISSN-L)
OpenAlex
W3206552555
Cited by
21
References
95
Citations by year
2026: 3 · 2025: 6 · 2024: 4 · 2023: 6 · 2022: 2
FWCI
1.69
Type
journal article
Language
en
Open access
Locations
  • Musculoskeletal Science and Practice (publishedVersion)
  • PubMed (publishedVersion)
  • UCL Discovery (University College London) (submittedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Connective tissue disorders research
  • Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Myofascial pain diagnosis and treatment
Keywords
joint hypermobility, hypermobile Ehlers-Danlos syndrome, connective tissue diseases, etiology, clinical features, assessment, biopsychosocial model, patient empowerment, functional restoration, diagnostic criteria
MeSH terms
Ehlers-Danlos Syndrome, Humans, Joint Instability, Movement, Pain, Patient Participation

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