The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Persistent cognitive dysfunction after traumatic brain injury: A dopamine hypothesis
Open accessAbstract
Traumatic brain injury (TBI) represents a significant cause of death and disability in industrialized countries. Of particular importance to patients the chronic effect that TBI has on cognitive function. Therapeutic strategies have been difficult to evaluate because of the complexity of injuries and variety of patient presentations within a TBI population. However, pharmacotherapies targeting dopamine (DA) have consistently shown benefits in attention, behavioral outcome, executive function, and memory. Still it remains unclear what aspect of TBI pathology is targeted by DA therapies and what time-course of treatment is most beneficial for patient outcomes. Fortunately, ongoing research in animal models has begun to elucidate the pathophysiology of DA alterations after TBI. The purpose of this review is to discuss clinical and experimental research examining DAergic therapies after TBI, which will in turn elucidate the importance of DA for cognitive function/dysfunction after TBI as well as highlight the areas that require further study.
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Cites
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Cited by
Molecular mechanisms of cognitive dysfunction following traumatic brain injury
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Illicit dopamine transients: reconciling actions of abused drugs
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All’s well that transcribes well: Non-coding RNAs and post-stroke brain damage
Vemuganti, R. (2013) · Neurochemistry International · doi:10.1016/j.neuint.2013.07.014 · Cited by 71
Chemokine CCL2 induces apoptosis in cortex following traumatic brain injury
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Amphetamine Elicits Opposing Actions on Readily Releasable and Reserve Pools for Dopamine
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Metadata
- Authors
- Bales, J. W., Wagner, A. K., Kline, A. E., & Dixon, C. E.
- Venue
- Neuroscience & Biobehavioral Reviews
- Publisher
- Elsevier BV
- Published
- 2009-07
- Volume
- 33
- Issue
- 7
- Pages
- 981-1003
- ISSN
- 0149-7634 (ISSN-L)
- OpenAlex
- W2136942291
- Cited by
- 264
- References
- 28
- FWCI
- 9.46
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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