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The effects of aging in the hippocampus and cognitive decline
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López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013) · Cell · doi:10.1016/j.cell.2013.05.039 · Cited by 14,982
The serial cultivation of human diploid cell strains
Hayflick, L., & Moorhead, P. S. (1961) · Experimental Cell Research · doi:10.1016/0014-4827(61)90192-6 · Cited by 8,508
Effects of stress throughout the lifespan on the brain, behaviour and cognition
Lupien, S. J., McEwen, B. S., Gunnar, M. R., & Heim, C. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2639 · Cited by 6,256
The senescence-associated secretory phenotype: the dark side of tumor suppression
Coppé, J.-P., Desprez, P.-Y., Krtolica, A., & Campisi, J. (2010) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathol-121808-102144 · Cited by 5,206
Cellular senescence: when bad things happen to good cells
Campisi, J., & d'Adda di Fagagna, F. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2233 · Cited by 4,441
Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus
van Praag, H., Kempermann, G., & Gage, F. H. (1999) · Nature Neuroscience · doi:10.1038/6368 · Cited by 3,880
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
Baker, D. J., Wijshake, T., Tchkonia, T., LeBrasseur, N. K., Childs, B. G., van de Sluis, B., Kirkland, J. L., & van Deursen, J. M. (2011) · Nature · doi:10.1038/nature10600 · Cited by 3,670 · cited 2×
“…that SC removal leads to rejuvenation of several tissues in aged mice, including an improvement in vascular phenotype (Roos et al., 2016), rejuvenation of hematopoietic stem cells (Chang et al., 2016), and attenuation of cataracts, sarcopenia, and lipodystrophy development (Baker et al., 2011).”
Be smart, exercise your heart: Exercise effects on brain and cognition
Hillman, C. H., Erickson, K. I., & Kramer, A. F. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2298 · Cited by 3,563
Cognitive reserve in ageing and Alzheimer's disease
Stern, Y. (2012) · The Lancet Neurology · doi:10.1016/s1474-4422(12)70191-6 · Cited by 3,557 · cited 1×
“Thus, exposure to a multitude of life experiences that can potentially stimulate brain plasticity (by increasing the number of neurons and synapses, decreasing apoptosis, and up-regulating neurotrophic support) may have a protective effect against various neuropathologies (Stern, 2012, 2009).”
Kuhn, H., Dickinson-Anson, H., & Gage, F. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-06-02027.1996 · Cited by 3,139
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Microbiota from young mice counteracts selective age-associated behavioral deficits
Boehme, M., Guzzetta, K. E., Bastiaanssen, T. F. S., van de Wouw, M., Moloney, G. M., Gual-Grau, A., Spichak, S., Olavarría-Ramírez, L., Fitzgerald, P., Morillas, E., et al. (2021) · Nature Aging · doi:10.1038/s43587-021-00093-9 · Cited by 313
Exploring the Role of Neuroplasticity in Development, Aging, and Neurodegeneration
Marzola, P., Melzer, T., Pavesi, E., Gil-Mohapel, J., & Brocardo, P. S. (2023) · Brain Sciences · doi:10.3390/brainsci13121610 · Cited by 281
Self-citationD’Amato, A., Di Cesare Mannelli, L., Lucarini, E., Man, A. L., Le Gall, G., Branca, J. J. V., Ghelardini, C., Amedei, A., Bertelli, E., Regoli, M., et al. (2020) · Microbiome · doi:10.1186/s40168-020-00914-w · Cited by 269
Polyphenols and neuroprotection: therapeutic implications for cognitive decline
Caruso, G., Torrisi, S. A., Mogavero, M. P., Currenti, W., Castellano, S., Godos, J., Ferri, R., Galvano, F., Leggio, G. M., Grosso, G., et al. (2022) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2021.108013 · Cited by 140
Neural ageing and synaptic plasticity: prioritizing brain health in healthy longevity
Navakkode, S., & Kennedy, B. K. (2024) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2024.1428244 · Cited by 75
Cellular senescence in the aging brain: A promising target for neurodegenerative diseases
Sahu, M. R., Rani, L., Subba, R., & Mondal, A. C. (2022) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2022.111675 · Cited by 75
Anti‐inflammatory treatment rescues memory deficits during aging in nfkb1−/− mice
Fielder, E., Tweedy, C., Wilson, C., Oakley, F., LeBeau, F. E. N., Passos, J. F., Mann, D. A., von Zglinicki, T., & Jurk, D. (2020) · Aging Cell · doi:10.1111/acel.13188 · Cited by 71
Cellular senescence as a driver of cognitive decline triggered by chronic unpredictable stress
Lin, Y.-F., Wang, L.-Y., Chen, C.-S., Li, C.-C., & Hsiao, Y.-H. (2021) · Neurobiology of Stress · doi:10.1016/j.ynstr.2021.100341 · Cited by 47
Interplay between hormones and exercise on hippocampal plasticity across the lifespan
Bettio, L. E. B., Thacker, J. S., Rodgers, S. P., Brocardo, P. S., Christie, B. R., & Gil-Mohapel, J. (2020) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2020.165821 · Cited by 40
Self-citationEpisodic-like memory is preserved with age in cuttlefish
Schnell, A. K., Clayton, N. S., Hanlon, R. T., & Jozet-Alves, C. (2021) · Proceedings of the Royal Society B: Biological Sciences · doi:10.1098/rspb.2021.1052 · Cited by 36
Rocha, B. S. (2021) · Frontiers in Aging · doi:10.3389/fragi.2021.778467 · Cited by 30
“These observations from the past 2 decades prompted several pre-clinical and clinical studies with the aim of using nitrate to prevent a wide range of diseases (Rammos et al., 2016; Bettio et al., 2017; Raubenheimer et al., 2017; Coggan and Peterson, 2018).”
BackgroundIs episodic-like memory like episodic memory?
Davies, J. R., & Clayton, N. S. (2024) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2023.0397 · Cited by 27
Rutschmann, R., Romanczuk-Seiferth, N., Gloster, A., & Richter, C. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1403718 · Cited by 21
Ping Pong: An Exergame for Cognitive Inhibition Training
Zhang, H., Shen, Z., Liu, S., Yuan, D., & Miao, C. (2021) · International Journal of Human–Computer Interaction · doi:10.1080/10447318.2020.1870826 · Cited by 19
Degradation of Caytaxin Causes Learning and Memory Deficits via Activation of DAPK1 in Aging
Guo, Y., Li, H., Ke, X., Deng, M., Wu, Z., Cai, Y., Afewerky, H. K., Zhang, X., Pei, L., & Lu, Y. (2019) · Molecular Neurobiology · doi:10.1007/s12035-018-1312-5 · Cited by 19
Liver-expressed antimicrobial peptide 2 elevation contributes to age-associated cognitive decline
Tian, J., Guo, L., Wang, T., Jia, K., Swerdlow, R. H., Zigman, J. M., & Du, H. (2023) · JCI Insight · doi:10.1172/jci.insight.166175 · Cited by 16
Route sequence knowledge supports the formation of cognitive maps
Hilton, C., & Wiener, J. (2023) · Hippocampus · doi:10.1002/hipo.23574 · Cited by 11
De Bellis, A., Gregoric, C., & Grant, J. (2023) · Journal of Intergenerational Relationships · doi:10.1080/15350770.2022.2073311 · Cited by 11
Aging and Its Societal Impact: A Bibliometric Analysis
Zheng, Z., B. A. M., H.-S., Omar Zaki, H., & Tan, Q. L. (2025) · SAGE Open · doi:10.1177/21582440251362564 · Cited by 6
Cai, M., Chen, S., Du, Y., Li, S., Dong, P., Wang, L., Yang, R., Hu, J., & Zhu, L. (2022) · Journal of Molecular Neuroscience · doi:10.1007/s12031-022-02052-4 · Cited by 4
Metadata
- Authors
- Bettio, L. E. B., Rajendran, L., & Gil-Mohapel, J.
- Venue
- Neuroscience & Biobehavioral Reviews
- Publisher
- Elsevier BV
- Published
- 2017-08
- Volume
- 79
- Pages
- 66-86
- ISSN
- 0149-7634 (ISSN-L)
- OpenAlex
- W2610521829
- Cited by
- 649
- References
- 100
- FWCI
- 12.24
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.