Role of growth hormone (GH) in the treatment on neural diseases: from neuroprotection to neural repair
Open accessAbstract
Growth hormone (GH) is a pleiotropic hormone that exerts important functions in the control of brain development as well as in the regulation neuronal differentiation and function, together with several behavioral and psychological effects that have been linked to its modulatory actions on brain neurotransmitters. In addition, the possibility that GH may play a role on brain repair after injury has been also envisaged, and a number of reports have shown that GH administration following injury confers neuroprotection and accelerates the recovery of some neural functions. In this review we have analyzed the state of the art of GH administration in several neural diseases. Though more studies are still necessary in order to completely understand the importance of GH in these processes, the promising results obtained so far, together with the absence of untoward effects during GH therapy, encourages the development of clinical assays in order to further support the use GH treatment in neural diseases in which neuroprotection and/or neuroregeneration are involved.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
GH may facilitate the proliferation, differentiation, and survival of new neurons in response to brain injury.
“Based on the experimental evidence, it was hypothesized that GH may facilitate the proliferation, differentiation, and survival of new neurons in response to brain injury (191,192).”
From Pituitary Dysfunction After Traumatic Brain Injury: A Clinical and Pathophysiological Approach (2015) · cites this paper as [191]
Cites
Gage, F. H. (2000) · Science · doi:10.1126/science.287.5457.1433 · Cited by 3,949 · see citing works
Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus
van Praag, H., Kempermann, G., & Gage, F. H. (1999) · Nature Neuroscience · doi:10.1038/6368 · Cited by 3,880 · see citing works
Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats
Altman, J., & Das, G. D. (1965) · Journal of Comparative Neurology · doi:10.1002/cne.901240303 · Cited by 3,592 · see citing works
More hippocampal neurons in adult mice living in an enriched environment
Kempermann, G., Kuhn, H. G., & Gage, F. H. (1997) · Nature · doi:10.1038/386493a0 · Cited by 3,513 · see citing works
Heart Disease and Stroke Statistics—2006 Update
Writing Group Members, Thom, T., Haase, N., Rosamond, W. D., Howard, V. J., Rumsfeld, J. S., Manolio, T. A., Zheng, Z., Flegal, K. M., O’Donnell, C. J., et al. (2006) · Circulation · doi:10.1161/circulationaha.105.171600 · Cited by 3,453 · see citing works
Mechanisms and Functional Implications of Adult Neurogenesis
Zhao, C., Deng, W., & Gage, F. H. (2008) · Cell · doi:10.1016/j.cell.2008.01.033 · Cited by 3,007 · see citing works
Functional neurogenesis in the adult hippocampus
van Praag, H., Schinder, A. F., Christie, B. R., Toni, N., Palmer, T. D., & Gage, F. H. (2002) · Nature · doi:10.1038/4151030a · Cited by 2,853 · see citing works
Neuronal replacement from endogenous precursors in the adult brain after stroke
Arvidsson, A., Collin, T., Kirik, D., Kokaia, Z., & Lindvall, O. (2002) · Nature Medicine · doi:10.1038/nm747 · Cited by 2,799 · see citing works
Parent, J. M., Yu, T. W., Leibowitz, R. T., Geschwind, D. H., Sloviter, R. S., & Lowenstein, D. H. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-10-03727.1997 · Cited by 1,853 · see citing works
Weissman, I. L. (2000) · Cell · doi:10.1016/s0092-8674(00)81692-x · Cited by 1,827 · see citing works
Asymmetric and symmetric stem-cell divisions in development and cancer
Morrison, S. J., & Kimble, J. E. (2006) · Nature · doi:10.1038/nature04956 · Cited by 1,393 · see citing works
Induction of neurogenesis in the neocortex of adult mice
Magavi, S. S. P., Leavitt, B. R., & Macklis, J. D. (2000) · Nature · doi:10.1038/35016083 · Cited by 1,217 · see citing works
Increased Neurogenesis in the Dentate Gyrus After Transient Global Ischemia in Gerbils
Liu, J., Solway, K., Messing, R. O., & Sharp, F. R. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-19-07768.1998 · Cited by 1,025 · see citing works
Rat forebrain neurogenesis and striatal neuron replacement after focal stroke
Parent, J. M., Vexler, Z. S., Gong, C., Derugin, N., & Ferriero, D. M. (2002) · Annals of Neurology · doi:10.1002/ana.10393 · Cited by 1,020 · see citing works
Clinical trials in head injury
Narayan, R. K., Michel, M. E., Ansell, B., Baethmann, A., Biegon, A., Bracken, M. B., Bullock, M. R., Choi, S. C., Clifton, G. L., Contant, C. F., et al. (2002) · Journal of Neurotrauma · doi:10.1089/089771502753754037 · Cited by 913 · see citing works
Peripheral Infusion of IGF-I Selectively Induces Neurogenesis in the Adult Rat Hippocampus
Åberg, M. A. I., Åberg, N. D., Hedbäcker, H., Oscarsson, J., & Eriksson, P. S. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-08-02896.2000 · Cited by 852 · see citing works
Treatment of adults with growth hormone (GH) deficiency with recombinant human GH.
Bengtsson, B. Å., Edén, S., Lönn, L., Kvist, H., Stokland, A. M., Lindstedt, G., Bosaeus, I. G., Tölli, J., Sjöström, L., & Isaksson, O. G. P. (1993) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.76.2.8432773 · Cited by 780 · see citing works
Yamashita, T., Ninomiya, M., Hernandez-Acosta, P., García‐Verdugo, J. M., Sunabori, T., Sakaguchi, M., Adachi, K., Kojima, T., Hirota, Y., Kawase, T., et al. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.0149-06.2006 · Cited by 720 · see citing works
Persistent Production of Neurons from Adult Brain Stem Cells During Recovery after Stroke
Thored, P., Arvidsson, A., Cacci, E., Ahlenius, H., Kallur, T., Darsalia, V., Ekdahl, C. T., Kokaia, Z., & Lindvall, O. (2005) · Stem Cells · doi:10.1634/stemcells.2005-0281 · Cited by 714 · see citing works
Auld, D. S., Kornecook, T. J., Bastianetto, S., & Quirion, R. (2002) · Progress in Neurobiology · doi:10.1016/s0301-0082(02)00079-5 · Cited by 669 · see citing works
Evidence for stroke-induced neurogenesis in the human brain
Jin, K., Wang, X., Xie, L., Mao, X. O., Zhu, W. P., Wang, Y., Shen, J., Mao, Y. Q., Banwait, S., & Greenberg, D. A. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0603512103 · Cited by 627 · see citing works
Schneider, H. J., Kreitschmann-Andermahr, I., Ghigo, E., Stalla, G. K., & Agha, A. (2007) · JAMA · doi:10.1001/jama.298.12.1429 · Cited by 549 · see citing works
Directed migration of neuronal precursors into the ischemic cerebral cortex and striatum
Jin, K., Sun, Y., Xie, L., Peel, A. L., Mao, X. O., Parmentier‐Batteur, S., & Greenberg, D. A. (2003) · Molecular and Cellular Neuroscience · doi:10.1016/s1044-7431(03)00159-3 · Cited by 515 · see citing works
Lichtenwalner, R. J., Forbes, M. E., Bennett, S. A., Lynch, C. D., Sonntag, W. E., & Riddle, D. R. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00378-5 · Cited by 428 · see citing works
Neal, C. R., Mansour, A., Reinscheid, R. K., Nothacker, H., Civelli, O., & Watson, S. J. (1999) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19990419)406:4 · Cited by 399 · see citing works
Cognitive functioning ten years following traumatic brain injury and rehabilitation.
Draper, K., & Ponsford, J. (2008) · Neuropsychology · doi:10.1037/0894-4105.22.5.618 · Cited by 380 · see citing works
Hypoxic-ischemic brain injury: Pathophysiology, neuropathology and mechanisms
Busl, K. M., & Greer, D. M. (2010) · Neurorehabilitation · doi:10.3233/nre-2010-0531 · Cited by 368 · see citing works
A placebo-controlled trial of insulin-like growth factor-I in amyotrophic lateral sclerosis
Borasio, G. D., Robberecht, W., Leigh, P. N., Emile, J., Guiloff, R. J., Jerusalem, F., Silani, V., Vos, P. E., Wokke, J. H. J., Dobbins, T., et al. (1998) · Neurology · doi:10.1212/wnl.51.2.583 · Cited by 339 · see citing works
Injury-Induced Neurogenesis in the Adult Mammalian Brain
Parent, J. M. (2003) · The Neuroscientist · doi:10.1177/1073858403252680 · Cited by 339 · see citing works
Krägeloh‐Mann, I., & Cans, C. (2009) · Brain and Development · doi:10.1016/j.braindev.2009.03.009 · Cited by 306 · see citing works
Adult Neurogenesis and the Ischemic Forebrain
Lichtenwalner, R. J., & Parent, J. M. (2005) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/sj.jcbfm.9600170 · Cited by 281 · see citing works
Subcutaneous IGF-1 is not beneficial in 2-year ALS trial
Sorenson, E. J., Windbank, A. J., Mandrekar, J. N., Bamlet, W. R., Appel, S. H., Armon, C., Barkhaus, P. E., Bosch, P., Boylan, K., David, W. S., et al. (2008) · Neurology · doi:10.1212/01.wnl.0000335970.78664.36 · Cited by 244 · see citing works
Nyberg, F. (2000) · Frontiers in Neuroendocrinology · doi:10.1006/frne.2000.0200 · Cited by 228 · see citing works
Gutiérrez‐Fernández, M., Rodríguez‐Frutos, B., Ramos‐Cejudo, J., Vallejo‐Cremades, M. T., Fuentes, B., Cerdán, S., & Díez‐Tejedor, E. (2013) · Stem Cell Research & Therapy · doi:10.1186/scrt159 · Cited by 228 · see citing works
Localization and ontogeny of growth hormone receptor gene expression in the central nervous system
Lobie, P. E., García-Aragón, J., Lincoln, D. T., Barnard, R. T., Wilcox, J. N., & Waters, M. J. (1993) · Developmental Brain Research · doi:10.1016/0165-3806(93)90008-x · Cited by 222 · see citing works
Signaling in adult neurogenesis
Mu, Y., Lee, S. W., & Gage, F. H. (2010) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2010.04.010 · Cited by 217 · see citing works
Long-term Neurologic Outcomes After Traumatic Brain Injury
Bazarian, J. J., Černak, I., Noble‐Haeusslein, L. J., Potolicchio, S. J., & Temkin, N. R. (2009) · Journal of Head Trauma Rehabilitation · doi:10.1097/htr.0b013e3181c15600 · Cited by 190 · see citing works
Effect of growth hormone replacement therapy on cognition after traumatic brain injury
High, W. M., Briones-Galang, M., Clark, J. A., Gilkison, C., Mossberg, K. A., Zgaljardic, D. J., Masel, B. E., & Urban, R. J. (2010) · Journal of Neurotrauma · doi:10.1089/neu.2009.1253 · Cited by 176 · see citing works
Growth hormone as a neuronal rescue factor during recovery from CNS injury
Scheepens, A., Sirimanne, E. S., Breier, B. H., Clark, R. G., Gluckman, P. D., & Williams, C. E. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00109-9 · Cited by 174 · see citing works
Local expression of GH and IGF-1 in the hippocampus of GH-deficient long-lived mice
Sun, L. Y., Al-Regaiey, K., Masternak, M. M., Wang, J., & Bartke, A. (2004) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2004.07.010 · Cited by 167 · see citing works
Falleti, M. G., Maruff, P., Burman, P., & Harris, A. (2006) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2006.01.005 · Cited by 165 · see citing works
Turnley, A. M., Faux, C. H., Rietze, R. L., Coonan, J. R., & Bartlett, P. F. (2002) · Nature Neuroscience · doi:10.1038/nn954 · Cited by 162 · see citing works
Kelly, D. F., McArthur, D. L., Levin, H., Swimmer, S., Dusick, J. R., Cohan, P., Wang, C., & Swerdloff, R. (2006) · Journal of Neurotrauma · doi:10.1089/neu.2006.23.928 · Cited by 158 · see citing works
Neurogenesis in the Adult Ischemic Brain: Generation, Migration, Survival, and Restorative Therapy
Zhang, R. L., Zhang, Z. G., & Chopp, M. (2005) · The Neuroscientist · doi:10.1177/1073858405278865 · Cited by 157 · see citing works
Human Dental Pulp-Derived Stem Cells Protect Against Hypoxic-Ischemic Brain Injury in Neonatal Mice
Yamagata, M., Yamamoto, A., Kako, E., Kaneko, N., Matsubara, K., Sakai, K., Sawamoto, K., & Ueda, M. (2012) · Stroke · doi:10.1161/strokeaha.112.676759 · Cited by 155 · see citing works
Permeation of Growth Hormone across the Blood-Brain Barrier
Pan, W., Yu, Y., Cain, C. M., Nyberg, F., Couraud, P. O., & Kastin, A. J. (2005) · Endocrinology · doi:10.1210/en.2005-0587 · Cited by 149 · see citing works
Current and Potentially New Management Strategies for Perinatal Hypoxic-Ischemic Encephalopathy
Vannucci, R. C. (1990) · PEDIATRICS · doi:10.1542/peds.85.6.961 · Cited by 147 · see citing works
García-Aragón, J., Lobie, P. E., Muscat, G. E. O., Gobius, K. S., Norstedt, G., & Waters, M. J. (1992) · Development · doi:10.1242/dev.114.4.869 · Cited by 145 · see citing works
Growth hormone is produced within the hippocampus where it responds to age, sex, and stress
Donahue, C. P., Kosik, K. S., & Shors, T. J. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0507776103 · Cited by 143 · see citing works
Frago, L., Pañeda, C., Dickson, S., Hewson, A. K., Argente, J., & Chowen, J. (2002) · Endocrinology · doi:10.1210/en.2002-220261 · Cited by 134 · see citing works
Cognitive sequelae of hypoxic-ischemic brain injury: A review
Anderson, C. A., & Arciniegas, D. B. (2010) · Neurorehabilitation · doi:10.3233/nre-2010-0535 · Cited by 132 · see citing works
Role of the Growth Hormone/Insulin-Like Growth Factor 1 Axis in Neurogenesis
Åberg, N. D. (2009) · Endocrine development · doi:10.1159/000262529 · Cited by 125 · see citing works
Blackmore, D. G., Golmohammadi, M. G., Large, B., Waters, M. J., & Rietze, R. L. (2009) · Stem Cells · doi:10.1002/stem.120 · Cited by 119 · see citing works
Grevès, M. L., Steensland, P., Grevès, P. L., & Nyberg, F. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.092135399 · Cited by 113 · see citing works
Growth Hormone Action on Proliferation and Differentiation of Cerebral Cortical Cells from Fetal Rat
Ajo, R., Cacicedo, L., Navarro, C., & Sánchez‐Franco, F. (2003) · Endocrinology · doi:10.1210/en.2002-220667 · Cited by 112 · see citing works
Reimunde, P., Quintana, A., Castañón, B., Casteleiro, N., Vilarnovo, Z., Otero, A., Devesa, A., Otero-Cepeda, X. L., & Devesa, J. (2011) · Brain Injury · doi:10.3109/02699052.2010.536196 · Cited by 100 · see citing works
Self-citationGrowth hormone and prolactin regulate human neural stem cell regenerative activity
Pathipati, P., Gorba, T., Scheepens, A., Goffin, V., Sun, Y., & Fraser, M. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.05.029 · Cited by 93 · see citing works
Possible Protective Role of Growth Hormone in Hypoxia-Ischemia in Neonatal Rats
Gustafson, K., Hagberg, H., Bengtsson, B., Brantsing, C., & Isgaard, J. (1999) · Pediatric Research · doi:10.1203/00006450-199903000-00005 · Cited by 90 · see citing works
Growth hormone (GH) and brain trauma
Devesa, J., Reimunde, P., Devesa, P., Barberá, M., & Arce, V. (2013) · Hormones and Behavior · doi:10.1016/j.yhbeh.2012.02.022 · Cited by 87 · see citing works
Self-citationNeural stem cells: From fly to vertebrates
Doe, C. Q., Fuerstenberg, S., & Peng, C. (1998) · Journal of Neurobiology · doi:10.1002/(sici)1097-4695(199808)36:2 · Cited by 85 · see citing works
Transcriptional profiling reveals regulated genes in the hippocampus during memory formation
Donahue, C. P., Jensen, R. V., Ochiishi, T., Eisenstein, I., Zhao, M., Shors, T. J., & Kosik, K. S. (2002) · Hippocampus · doi:10.1002/hipo.10058 · Cited by 85 · see citing works
Harvey, S., & Hull, K. (1997) · Endocrine · doi:10.1007/bf02801319 · Cited by 83 · see citing works
Aimone, J. B., & Gage, F. H. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07615.x · Cited by 77 · see citing works
Shin, D. H., Lee, E., Kim, J.-W., Kwon, B. S., Jung, M. K., Jee, Y. H., Kim, J., Bae, S.-R., & Chang, Y. P. (2003) · Neuroscience Letters · doi:10.1016/j.neulet.2003.09.070 · Cited by 75 · see citing works
Neurological sequelae of hypoxic-ischemic brain injury
Lu‐Emerson, C., & Khot, S. P. (2010) · Neurorehabilitation · doi:10.3233/nre-2010-0534 · Cited by 73 · see citing works
Neurogenesis in the human hippocampus and its relevance to temporal lobe epilepsies
Siebzehnrübl, F. A., & Blümcke, I. (2008) · Epilepsia · doi:10.1111/j.1528-1167.2008.01638.x · Cited by 73 · see citing works
Exogenous growth hormone attenuates cognitive deficits induced by intermittent hypoxia in rats
Li, R. C., Guo, S. Z., Raccurt, M., Moudilou, E., Morel, G., Brittian, K. R., & Gozal, D. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.08.029 · Cited by 72 · see citing works
Lichtenwalner, R. J., Forbes, M. E., Sonntag, W. E., & Riddle, D. R. (2005) · Journal of Neuroscience Research · doi:10.1002/jnr.20719 · Cited by 70 · see citing works
Recombinant growth hormone treatment of amyotrophic lateral sclerosis
Smith, R. A., Melmed, S. K., Sherman, B. M., France, J., Munsat, T. L., & Festoff, B. W. (1993) · Muscle & Nerve · doi:10.1002/mus.880160608 · Cited by 70 · see citing works
High, W. M., Roebuck‐Spencer, T., Sander, A. M., Struchen, M. A., & Sherer, M. (2006) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2005.11.028 · Cited by 69 · see citing works
Schneider-Rivas, S., Rivas-Arancibia, S., Vázquez-Pereyra, F., Vázquez-Sandoval, R., & Borgonio-Pérez, G. (1995) · Life Sciences · doi:10.1016/0024-3205(95)00171-2 · Cited by 69 · see citing works
Laron Syndrome: Clinical Features, Molecular Pathology and Treatment
Laron, Z., & Klinger, B. (2008) · Hormone Research · doi:10.1159/000184193 · Cited by 68 · see citing works
Kreitschmann-Andermahr, I., Poll, E. M., Reineke, A., Gilsbach, J. M., Brabant, G., Buchfelder, M., Faßbender, W., Faust, M., Kann, P. H., & Wallaschofski, H. (2008) · Growth Hormone & IGF Research · doi:10.1016/j.ghir.2008.08.007 · Cited by 68 · see citing works
Yoshizato, H., Fujikawa, T., Soya, H., Tanaka, M., & Nakashima, K. (1998) · Endocrinology · doi:10.1210/endo.139.5.6009 · Cited by 66 · see citing works
Åberg, N. D., Johansson, I., Åberg, M., Lind, J., Johansson, U. E., Cooper‐Kuhn, C. M., Kuhn, H. G., & Isgaard, J. (2009) · Journal of Endocrinology · doi:10.1677/joe-08-0495 · Cited by 65 · see citing works
Alterations in the neural growth hormone axis following hypoxic–ischemic brain injury
Scheepens, A., Sirimanne, E. S., Beilharz, E. J., Breier, B. H., Waters, M. J., Gluckman, P. D., & Williams, C. E. (1999) · Molecular Brain Research · doi:10.1016/s0169-328x(99)00051-0 · Cited by 64 · see citing works
Seale, G., Caroselli, J., High, W., Becker, C., Neese, L., & Scheibel, R. (2002) · Brain Injury · doi:10.1080/02699050210155258 · Cited by 64 · see citing works
Cyclosporin A disposition following acute traumatic brain injury
Empey, P. E., McNamara, P. J., Young, B., Rosbolt, M. B., & Hatton, J. (2006) · Journal of Neurotrauma · doi:10.1089/neu.2006.23.109 · Cited by 58 · see citing works
Sander, A. M., Roebuck, T. M., Struchen, M. A., Sherer, M., & High, W. M. (2001) · Journal of Head Trauma Rehabilitation · doi:10.1097/00001199-200108000-00006 · Cited by 58 · see citing works
Growth hormone prevents human immunodeficiency virus–induced neuronal p53 expression
Silva, C., Zhang, K., Tsutsui, S., Holden, J. K., Gill, M. J., & Power, C. (2003) · Annals of Neurology · doi:10.1002/ana.10729 · Cited by 57 · see citing works
Tanriverdi, F., Unluhizarci, K., Karaca, Z., Casanueva, F. F., & Kelestimur, F. (2010) · Pituitary · doi:10.1007/s11102-009-0204-0 · Cited by 56 · see citing works
Saccà, F., Quarantelli, M., Rinaldi, C., Tucci, T., Piro, R., Perrotta, G., Carotenuto, B., Marsili, A., Palma, V., Michele, G., et al. (2011) · Journal of Neurology · doi:10.1007/s00415-011-6146-2 · Cited by 56 · see citing works
Effects of Growth Hormone on Cerebral Development: Morphological Studies
Noguchi, T. (2008) · Hormone Research · doi:10.1159/000184752 · Cited by 54 · see citing works
Devesa, P., Reimunde, P., Gallego, R., Devesa, J., & Arce, V. M. (2011) · Brain Injury · doi:10.3109/02699052.2011.559611 · Cited by 52 · see citing works
Self-citationGrowth hormone: neurocrine and neuroendocrine perspectives.
Harvey, S., Hull, K., & Fräser, R. A. (1993) · PubMed · Cited by 51 · see citing works
Christophidis, L. J., Gorba, T., Gustavsson, M., Williams, C. E., Werther, G. A., Russo, V. C., & Scheepens, A. (2009) · Growth Hormone & IGF Research · doi:10.1016/j.ghir.2009.05.001 · Cited by 50 · see citing works
Growth hormone promotes proliferation of adult neurosphere cultures
McLenachan, S., Lum, M., Waters, M. J., & Turnley, A. M. (2008) · Growth Hormone & IGF Research · doi:10.1016/j.ghir.2008.09.003 · Cited by 49 · see citing works
Pelton, E. W., Grindeland, R. E., Young, E. A., & Bass, N. H. (1977) · Neurology · doi:10.1212/wnl.27.3.282 · Cited by 49 · see citing works
Fujikawa, T., Soya, H., Fukuoka, H., Alam, K. S. M., Yoshizato, H., McEwen, B. S., & Nakashima, K. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02576-2 · Cited by 48 · see citing works
Hatton, J., Kryscio, R., Ryan, M., Ott, L., & Young, B. (2006) · Journal of Neurosurgery · doi:10.3171/jns.2006.105.6.843 · Cited by 48 · see citing works
Growth Hormone, Fatigue, Poor Sleep, and Disability in HIV Infection
Darko, D. F., Mitler, M. M., & Miller, J. C. (1998) · Neuroendocrinology · doi:10.1159/000054329 · Cited by 47 · see citing works
Cognitive Function in Growth Hormone Deficiency and Growth Hormone Replacement
Maruff, P. T., & Downing, M. G. (2005) · Hormone Research in Paediatrics · doi:10.1159/000089325 · Cited by 46 · see citing works
Pavlovic, D., Pekić, S., Stojanović, M., Zivkovic, V., Djurovic, B., Jovanovic, V., Miljic, N., Medic‐Stojanoska, M., Doknić, M., Miljić, D., et al. (2009) · European Journal of Neurology · doi:10.1111/j.1468-1331.2009.02910.x · Cited by 44 · see citing works
Expression of growth hormone receptor in the human brain
Castro, J. R., Costoya, J. A., Gallego, R., Prieto, A., Arce, V. M., & Señarís, R. M. (2000) · Neuroscience Letters · doi:10.1016/s0304-3940(00)00830-2 · Cited by 43 · see citing works
Self-citationThe response of growth hormone and prolactin of rats to hypoxia
Zhang, Y. (2000) · Neuroscience Letters · doi:10.1016/s0304-3940(99)00968-4 · Cited by 43 · see citing works
Puberty, statural growth, and growth hormone release in children with cerebral palsy
Kuperminc, M. N., Gurka, M. J., Houlihan, C. M., Henderson, R. C., Roemmich, J. N., Rogol, A. D., & Stevenson, R. D. (2009) · Journal of Pediatric Rehabilitation Medicine · doi:10.3233/prm-2009-0072 · Cited by 40 · see citing works
Growth hormone secretion is impaired in amyotrophic lateral sclerosis
Morselli, L. L., Bongioanni, P., Genovesi, M., Licitra, R., Rossi, B., Murri, L., Rossi, G., Martino, E., & Gasperi, M. (2006) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2006.02609.x · Cited by 39 · see citing works
Growth hormone deficiency and cerebral palsy
Devesa, J., & Casteleiro, N. (2010) · Therapeutics and Clinical Risk Management · doi:10.2147/tcrm.s12312 · Cited by 38 · see citing works
Self-citationÅberg, N. D., Johansson, U. E., Åberg, M., Erkenstam, N. H., Lind, J., Bull, C., Isgaard, J., Anderson, M. F., Oscarsson, J., & Eriksson, P. S. (2007) · Endocrinology · doi:10.1210/en.2006-1556 · Cited by 38 · see citing works
Adult Neurogenesis in the Hippocampus of Long-Lived Mice During Aging
Sun, L. Y., & Bartke, A. (2007) · The Journals of Gerontology Series A · doi:10.1093/gerona/62.2.117 · Cited by 37 · see citing works
Marchesi, V. T. (2012) · American Journal Of Pathology · doi:10.1016/j.ajpath.2012.03.004 · Cited by 36 · see citing works
Lyuh, E., Kim, H., Kim, M., Lee, J., Park, K. S., Yoo, K., Lee, K., & Ahn, Y. (2007) · Growth Hormone & IGF Research · doi:10.1016/j.ghir.2007.03.002 · Cited by 35 · see citing works
Bhagia, V., Gilkison, C., Fitts, R. H., Zgaljardic, D. J., High, W. M., Masel, B. E., Urban, R. J., & Mossberg, K. A. (2010) · Brain Injury · doi:10.3109/02699051003601705 · Cited by 35 · see citing works
Sm, H., McKenna, S. P., & Doward, L. C. (1993) · PubMed · Cited by 35 · see citing works
Delayed and chronic treatment with growth hormone after endothelin-induced stroke in the adult rat
Pathipati, P., Surus, A., Williams, C. E., & Scheepens, A. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.05.023 · Cited by 34 · see citing works
Growth hormone signaling and hippocampal neurogenesis: Insights from genetic models
Ransome, M. I., & Turnley, A. M. (2008) · Hippocampus · doi:10.1002/hipo.20463 · Cited by 33 · see citing works
Links between Growth Hormone Deficiency, Adaptation and Social Phobia
Stabler, B., Clopper, R. R., Siegel, P. T., Nicholas, L. M., Silva, S. G., Tancer, M. E., & Underwood, L. E. (2008) · Hormone Research · doi:10.1159/000184755 · Cited by 32 · see citing works
van Marle, G., Antony, J. M., Silva, C., Sullivan, A., & Power, C. (2005) · AIDS · doi:10.1097/01.aids.0000189854.06194.87 · Cited by 32 · see citing works
Devesa, J., Alonso, Casteleiro, Couto, Castanón, Zas, & Reimunde, P. (2011) · Therapeutics and Clinical Risk Management · doi:10.2147/tcrm.s21403 · Cited by 30 · see citing works
Self-citationIs treatment with growth hormone effective in children with cerebral palsy?
Shim, M. L., Moshang, T., Oppenheim, W. L., & Cohen, P. (2004) · Developmental Medicine & Child Neurology · doi:10.1017/s0012162204000945 · Cited by 27 · see citing works
Hormona de crecimiento: acciones y aplicaciones preventivas y terapéuticas
Devesa, J., Devesa, P., & Reimunde, P. (2010) · Medicina Clínica · doi:10.1016/j.medcli.2009.10.017 · Cited by 26 · see citing works
Self-citationDistinct role of growth hormone on epilepsy progression in a model of temporal lobe epilepsy
Kato, K., Suzuki, M., Kanno, H., Sekino, S., Kusakabe, K. T., Okada, T., Mori, T., Yoshida, K., & Hirabayashi, Y. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.06132.x · Cited by 25 · see citing works
Devesa, J., & Casteleiro, N. (2010) · Therapeutics and Clinical Risk Management · doi:10.2147/tcrm.s14919 · Cited by 22 · see citing works
Self-citationEvaluation of the Errorless Learning Technique in Children With Traumatic Brain Injury
Landis, J., Hanten, G. R., Levin, H. S., Li, X., Ewing‐Cobbs, L., Duron, J., & High, W. M. (2006) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2006.02.017 · Cited by 22 · see citing works
Doulah, A., Rohani, A. H., Khaksari, M., Motamedi, F., Farbood, Y., Badavi, M., Malek, M., & Sarkaki, A. (2009) · Neuroscience Letters · doi:10.1016/j.neulet.2009.09.016 · Cited by 21 · see citing works
Ling, F. A., Hui, D. Z., & Ji, S. M. (2007) · Growth Hormone & IGF Research · doi:10.1016/j.ghir.2007.04.012 · Cited by 21 · see citing works
Song, J., Park, K., Lee, H.-I., & Kim, M. (2012) · Annals of Rehabilitation Medicine · doi:10.5535/arm.2012.36.4.447 · Cited by 21 · see citing works
Retarded cerebral growth of hormone-deficient mice
Noguchi, T. (1991) · Comparative Biochemistry and Physiology Part C Comparative Pharmacology · doi:10.1016/0742-8413(91)90200-d · Cited by 20 · see citing works
Is treatment with growth hormone effective in children with cerebral palsy?
Shim, M. L., Moshang, T., Oppenheim, W. L., et al. (2004) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.2004.tb01016.x · Cited by 20 · see citing works
Distinct neuronal growth hormone receptor ligand specificity in the rat brain
Möderscheim, T. A. E., Christophidis, L. J., Williams, C. E., & Scheepens, A. (2006) · Brain Research · doi:10.1016/j.brainres.2006.12.040 · Cited by 18 · see citing works
Growth Hormone Deficiency in Two Children with Cerebral Palsy
Coniglio, S. J., & Stevenson, R. D. (1995) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.1995.tb11957.x · Cited by 17 · see citing works
Endocrine Changes in a Rat Model of Chronic Hypoxia Mimicking Cyanotic Heart Disease
Zayour, D. H., Azar, S. T., Azar, N. J., Nasser, M., Obeid, M. Y., Mroueh, S. M., Dbaibo, G. S., & Bitar, F. F. (2003) · Endocrine Research · doi:10.1081/erc-120022301 · Cited by 16 · see citing works
Christman, G. M., & Halme, J. K. (1992) · Fertility and Sterility · doi:10.1016/s0015-0282(16)54768-2 · Cited by 16 · see citing works
Han, T. R., Chun, M. H., Jang, D. H., Kim, K. S., Lim, K. H., & Cho, H. J. (2007) · Journal of Korean Medical Science · doi:10.3346/jkms.2007.22.1.122 · Cited by 13 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Pituitary Dysfunction After Traumatic Brain Injury: A Clinical and Pathophysiological Approach
Tanriverdi, F., Schneider, H. J., Aimaretti, G., Masel, B. E., Casanueva, F. F., & Kelestimur, F. (2015) · Endocrine Reviews · doi:10.1210/er.2014-1065 · Cited by 218 · see citing works
Multiple Effects of Growth Hormone in the Body: Is it Really the Hormone for Growth?
Devesa, J., Almengló, C., & Devesa, P. (2016) · Clinical Medicine Insights Endocrinology and Diabetes · doi:10.4137/cmed.s38201 · Cited by 153 · see citing works
Self-citationHarguindey, S., Stanciu, D., Devesa, J., Alfarouk, K. O., Cardone, R. A., Orozco, J. D. P., Devesa, P., Rauch, C., Orive, G., Anitua, E., et al. (2017) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2017.02.003 · Cited by 75 · see citing works
Self-citationvan der Spoel, E., Jansen, S. W. M., Akintola, A. A., Ballieux, B. E. P. B., Cobbaert, C. M., Slagboom, P. E., Blauw, G. J., Westendorp, R. G. J., Pijl, H., Roelfsema, F., et al. (2016) · Aging Cell · doi:10.1111/acel.12519 · Cited by 64 · see citing works
Expression and function of growth hormone in the nervous system: A brief review
Arámburo, C., Betancourt, C. A., Luna, M., & Harvey, S. (2014) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2014.04.035 · Cited by 55 · see citing works
Martínez-Moreno, C. G., Calderón-Vallejo, D., Harvey, S., Arámburo, C., & Quintanar, J. L. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19020375 · Cited by 51 · see citing works
Treatment of autistic spectrum disorder with insulin-like growth factors
Riikonen, R. (2016) · European Journal of Paediatric Neurology · doi:10.1016/j.ejpn.2016.08.005 · Cited by 50 · see citing works
Devesa, P., Agasse, F., Xapelli, S., Almengló, C., Devesa, J., Malva, J. O., & Arce, V. M. (2014) · BMC Neuroscience · doi:10.1186/1471-2202-15-100 · Cited by 47 · see citing works
Self-citationDetection of Growth Hormone Deficiency in Adults with Chronic Traumatic Brain Injury
Kreber, L. A., Griesbach, G. S., & Ashley, M. J. (2016) · Journal of Neurotrauma · doi:10.1089/neu.2015.4127 · Cited by 44 · see citing works
Wright, T. J., Urban, R. J., Durham, W., Dillon, E. L., Randolph, K. M., Danesi, C. P., Gilkison, C. R., Karmonik, C., Zgaljardic, D. J., Masel, B. E., et al. (2019) · Journal of Neurotrauma · doi:10.1089/neu.2019.6690 · Cited by 39 · see citing works
Martínez-Moreno, C. G., Fleming, T., Carranza, M., Ávila-Mendoza, J., Luna, M., Harvey, S., & Arámburo, C. (2017) · Experimental Eye Research · doi:10.1016/j.exer.2017.10.005 · Cited by 38 · see citing works
Clinical picture and the treatment of TBI-induced hypopituitarism
Caputo, M., Mele, C., Prodam, F., Marzullo, P., & Aimaretti, G. (2019) · Pituitary · doi:10.1007/s11102-019-00956-w · Cited by 39 · see citing works
Devesa, J., Díaz-Getino, G., Rey, P., García-Cancela, J., Loures, I., Nogueiras, S., de Mendoza, A. H., Salgado, L., González, M., Pablos, T., et al. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms161226244 · Cited by 35 · see citing works
Self-citationStelzhammer, V., Alsaif, M., Chan, M. K., Rahmoune, H., Steeb, H., Guest, P. C., & Bahn, S. (2014) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2014.09.022 · Cited by 33 · see citing works
Neuroprotection by GH against excitotoxic-induced cell death in retinal ganglion cells
Martínez-Moreno, C. G., Ávila-Mendoza, J., Wu, Y., Arellanes-Licea, E. D. C., Louie, M., Luna, M., Arámburo, C., & Harvey, S. (2016) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2016.03.023 · Cited by 26 · see citing works
Learning and Memory Recoveries in a Young Girl Treated with Growth Hormone and Neurorehabilitation
Devesa, J., Lema, H., Zas, E., Munín, B., Taboada, P., & Devesa, P. (2016) · Journal of Clinical Medicine · doi:10.3390/jcm5020014 · Cited by 25 · see citing works
Self-citationKuppens, R. J., Mahabier, E. F., Bakker, N. E., Siemensma, E. P. C., Donze, S., & Hokken‐Koelega, A. C. S. (2016) · Orphanet Journal of Rare Diseases · doi:10.1186/s13023-016-0535-7 · Cited by 23 · see citing works
Growth hormone (GH) and synaptogenesis
Martínez-Moreno, C. G., & Arámburo, C. (2020) · Vitamins and hormones · doi:10.1016/bs.vh.2020.04.001 · Cited by 23 · see citing works
Devesa, J., Alonso, A., López, N., García, J., Puell, C. I., Pablos, T., & Devesa, P. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18010230 · Cited by 22 · see citing works
Self-citationPharmacological management of secondary chronic spinal cord injury: a systematic review
Migliorini, F., Cocconi, F., Schäfer, L., Simeone, F., Jeyaraman, M., & Maffulli, N. (2024) · British Medical Bulletin · doi:10.1093/bmb/ldae009 · Cited by 21 · see citing works
Growth hormone reverses excitotoxic damage induced by kainic acid in the green iguana neuroretina
Ávila-Mendoza, J., Mora‐Zenil, J., Carranza, M., Luna, M., & Arámburo, C. (2016) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2016.04.004 · Cited by 21 · see citing works
Burkhart, A., Andresen, T. L., Aigner, A. M., Thomsen, L. B., & Moos, T. (2017) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-017-2501-5 · Cited by 18 · see citing works
Growth hormone and ocular dysfunction: Endocrine, paracrine or autocrine etiologies?
Harvey, S., & Martínez-Moreno, C. G. (2016) · Growth Hormone & IGF Research · doi:10.1016/j.ghir.2016.03.004 · Cited by 18 · see citing works
Kim, M., Chung, J.-Y., Sunwoo, J., & Kim, M.-W. (2015) · Neural Regeneration Research · doi:10.4103/1673-5374.162690 · Cited by 17 · see citing works
Almengló, C., Devesa, P., Devesa, J., & Arce, V. M. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18061280 · Cited by 16 · see citing works
Self-citationOlivares‐Hernández, J. D., Balderas-Márquez, J. E., Carranza, M., Luna, M., Martínez-Moreno, C. G., & Arámburo, C. (2021) · Neural Plasticity · doi:10.1155/2021/9990166 · Cited by 16 · see citing works
Baltazar-Lara, R., Mora‐Zenil, J., Carranza, M., Ávila-Mendoza, J., Martínez-Moreno, C. G., Arámburo, C., & Luna, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231911546 · Cited by 16 · see citing works
Jung, S., Terörde, K., Dörr, H., & Trollmann, R. (2021) · Endocrinology · doi:10.1210/endocr/bqab008 · Cited by 14 · see citing works
Olivares‐Hernández, J. D., Carranza, M., Balderas-Márquez, J. E., Epardo, D., Baltazar-Lara, R., Ávila-Mendoza, J., Martínez-Moreno, C. G., Luna, M., & Arámburo, C. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23169054 · Cited by 16 · see citing works
Hou, C., Zhang, R., Zhang, K., & Chen, X. (2017) · Metabolic Brain Disease · doi:10.1007/s11011-017-0082-5 · Cited by 14 · see citing works
Barceló, P., Nicolau, C., Gamundı́, A., Fiol-deRoque, M. A., Tresguerres, J. A. F., Akaârir, M., & Rial, R. V. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/5863402 · Cited by 11 · see citing works
Heredia, M., Rodríguez, N., Sánchez‐Robledo, V., Criado, J. M., de la Fuente, A., Devesa, J., Devesa, P., & Riolobos, A. S. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20225770 · Cited by 10 · see citing works
Self-citationJung, S., Boie, G., Doerr, H.-G., & Trollmann, R. (2017) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00477.2016 · Cited by 10 · see citing works
Trueba-Timmermans, D. J., Grootjen, L. N., Juriaans, A. F., Mahabier, E. F., Kerkhof, G. F., Rings, E. H. H. M., & Hokken-Koelega, A. (2023) · European Journal of Endocrinology · doi:10.1093/ejendo/lvad084 · Cited by 10 · see citing works
Upregulation of GH, but not IGF1, in the hippocampus of the lactating dam after kainic acid injury
Arellanes-Licea, E. D. C., Ávila-Mendoza, J., Ramírez-Martínez, E. C., Ramos, E., Uribe-González, N., Arámburo, C., Morales, T., & Luna, M. (2018) · Endocrine Connections · doi:10.1530/ec-17-0380 · Cited by 9 · see citing works
Growth hormone rescue cerebellar degeneration in SCA3 transgenic mice
Wu, S., Liu, K., Cheng, W., Su, S., Lin, Y.-S., Lin, T., Cheng, Y., Chang, J., Wu, Y., & Liu, C. (2020) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2020.05.116 · Cited by 7 · see citing works
Ávila-Mendoza, J., Delgado-Rueda, K., Urban-Sosa, V. A., Carranza, M., Luna, M., Martínez-Moreno, C. G., & Arámburo, C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241311187 · Cited by 6 · see citing works
Neural stem cells and glioblastoma stem cells: Redefining concepts
Arce, V. M., Gonzalez-Rendo, L., Porres-Ventin, L., González-Álvarez, V., Caamaño-Teixeira, S., Almengló, C., Señarís, R. M., & Costoya, J. A. (2026) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2026.105187 · Cited by 5 · see citing works
Self-citationGrowth Hormone Neuroprotective Effects After an Optic Nerve Crush in the Male Rat
Epardo, D., Balderas-Márquez, J. E., Rodríguez-Arzate, C. A., Thébault, S. C., Carranza, M., Luna, M., Ávila-Mendoza, J., Calderón-Vallejo, D., Quintanar, J. L., Arámburo, C., et al. (2024) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.65.13.17 · Cited by 5 · see citing works
Quintana, A., Agra, C., Outeiral, L., Devesa, A., Llorente, D., & Devesa, J. (2018) · Reports — Medical Cases Images and Videos · doi:10.3390/reports1010002 · Cited by 4 · see citing works
Self-citationHarguindey, S., Alfarouk, K. O., Orozco, J. D. P., Reshkin, S. J., & Devesa, J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23052454 · Cited by 7 · see citing works
Self-citationFrom neural stem cells to glioblastoma: A natural history of GBM recapitulated in vitro
Almengló, C., Caamaño, P., Fraga, M., Devesa, J., Costoya, J. A., & Arce, V. M. (2021) · Journal of Cellular Physiology · doi:10.1002/jcp.30409 · Cited by 5 · see citing works
Self-citationDevesa, J., Fresco, C., Devesa, A., Rodríguez, A., & de Souza, D. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26041627 · Cited by 3 · see citing works
Self-citationRen, Y., Ren, Z., Zhao, S., Wu, W., Wang, J., He, F., Zhong, Q., Zhang, H., Chen, J., Xu, K., et al. (2025) · Translational Psychiatry · doi:10.1038/s41398-025-03750-4 · Cited by 3 · see citing works
Approach to the Patient With Traumatic Brain Injury–induced Pituitary Dysfunction
Keleştimur, F., Agha, A., Ioachimescu, A. G., McDonald, D., Karaca, Z., & Yuen, K. C. J. (2026) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgag090 · Cited by 3 · see citing works
The role of growth hormone in hippocampal function
Juárez‐Aguilar, E., Olivares‐Hernández, J. D., Regalado‐Santiago, C., & García‐García, F. (2022) · Vitamins and hormones · doi:10.1016/bs.vh.2021.11.007 · Cited by 3 · see citing works
Growth Hormone and the Auditory Pathway: Neuromodulation and Neuroregeneration
Guerra, J., & Devesa, J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22062829 · Cited by 3 · see citing works
Self-citationChen, G., Shao, H., & Pan, X. (2016) · Biomedical Reports · doi:10.3892/br.2016.635 · Cited by 2 · see citing works
The interplay between neuroendocrine and sleep alterations following traumatic brain injury
Howell, S., & Griesbach, G. S. (2018) · Neurorehabilitation · doi:10.3233/nre-182483 · Cited by 2 · see citing works
Zamora-Bello, I., Martínez, A. L., Beltrán‐Parrazal, L., Roque, I. S., Juárez‐Aguilar, E., & López‐Meraz, M. L. (2021) · Neurología · doi:10.1016/j.nrl.2021.03.010 · Cited by 2 · see citing works
de Ruz, A. E., Rodríguez-Carrión, I., Ceruelo-Abajo, S., García, R. P., Loro, F. A., Carrasco-López, C., Alcobendas-Maestro, M., Casado-López, R., Talavera-Díaz, F., Soto-León, V., et al. (2021) · Spinal Cord · doi:10.1038/s41393-021-00662-0 · Cited by 2 · see citing works
Woo, Q. Y., Lee, B. T. K., Lim, L. W., Zhang, J., Tashiro, A., Lau, P. K., Thibault, G., Wang, Y., & Lin, V. C. L. (2025) · Nutritional Neuroscience · doi:10.1080/1028415x.2025.2546946 · Cited by 2 · see citing works
Heredia, M., Sánchez‐Robledo, V., Gómez, I., Criado, J. M., de la Fuente, A., Devesa, J., Devesa, P., & Riolobos, A. S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22115440 · Cited by 2 · see citing works
Self-citationMechanisms of Circadian Rhythm Regulation in Humans
Kanarskii, M. M., Nekrasova, J. Y., Kurova, N. A., & Редкин, И. В. (2022) · Human Physiology · doi:10.1134/s0362119722020098 · Cited by 1 · see citing works
Kirazlı, Ö., Özkan, M., Verimli, U., Aker, R. G., Arman, A., & Sehirli, U. S. (2024) · Anatomical Science International · doi:10.1007/s12565-024-00790-6 · Cited by 1 · see citing works
Neuroprotection, Photoperiod, and Sleep
Martínez-Vargas, M., Villalobos, M. G. P., Estrada-Rojo, F., Tapia, R., Pérez-Arredondo, A., Barajas‐Martínez, A., & Navarro, L. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.85013 · Cited by 1 · see citing works
Hernández, M. I. M., & Luz, E. (2015)
Fever Due to Infection or Muscle Heat?
Devesa, J. (2017) · MOJ Anatomy & Physiology · doi:10.15406/mojap.2017.03.00118
Self-citationDevesa, J., Alonso, A., Porto, P., Quintana, A., Carrillo, M., Devesa, P., & Puell, C. I. (2017) · Preprints.org · doi:10.20944/preprints201708.0106.v1
Self-citationGrowth Hormone and Synaptogenesis in the Chick Retina
Fleming, T. (2018) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r3cj8818f
Growth Hormone Deficiency: Is It Just a Problem of Growth Impairment? Part I
Devesa, J. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.88837
Self-citationFrom Neural Stem Cells (NSC) to Glioblastoma (GBM): A Natural History of GBM Recapitulated in VitroPreprint
Almengló, C., Caamaño, P., Fraga, M., Devesa, J., Costoya, J. A., & Arce, V. M. (2020) · Preprints.org · doi:10.20944/preprints202008.0637.v1
Self-citationBasic considerations on growth hormone deficiency in traumatic brain injury
Lozada-Martínez, I. D., Ortega-Sierra, M. G., Daza-Vega, M. M., Cárdenas-Hormiga, L. N., Contreras-Saldarriaga, J. E., Garcia-Moron, C. E., Serna–Trejos, J. S., Nuñez-Gamez, J. A., Gómez-Murillo, D., Rosero-Burgos, M. E., et al. (2021) · Romanian Neurosurgery · doi:10.33962/roneuro-2021-082
Zamora-Bello, I., & López‐Meraz, M. L. (2020) · eNeurobiología · doi:10.25009/eb.v11i28.2560
Growth Hormone and Visual Stimulation Restore Normal Vision in Children with Cerebral Palsy
Myradova, S., Devesa, P., Guerra, J., & Devesa, J. (2022) · Medical Research Archives · doi:10.18103/mra.v10i9.3069
Self-citationZamora-Bello, I., Martínez, A. L., Beltrán‐Parrazal, L., Roque, I. S., Juárez‐Aguilar, E., & López‐Meraz, M. L. (2023) · Neurología (English Edition) · doi:10.1016/j.nrleng.2023.12.003
Kirazlı, Ö., Efekan, H., Acinikli, M., Öztürk, M., Demir, S., Büyükyılmaz, Z., & Sehirli, U. S. (2025) · Marmara medical journal · doi:10.5472/marumj.1627842
Woo, Q. Y., Lee, B. T. K., Lim, L. W., Zhang, J., Tashiro, A., Lau, P. K., Thibault, G., Wang, Y., & Lin, V. C. L. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.05.22.655437
Haddock, M. L., Krishna, G., Yuen, K. C. J., & Thomas, T. C. (2026) · Growth Hormone & IGF Research · doi:10.1016/j.ghir.2026.101729
- Authors
- Arce, V. M., Devesa, P., & Devesa, J.
- Affiliations
- Universidade de Santiago de Compostela (ES)
- Corresponding author
- Devesa, Jesús
- ORCID
- Devesa, Jesús
- Venue
- Neuroscience Research
- Publisher
- Elsevier BV
- Published
- 2013-08
- Volume
- 76
- Issue
- 4
- Pages
- 179-186
- ISSN
- 0168-0102 (ISSN-L)
- OpenAlex
- W2086179172
- Cited by
- 70
- References
- 123
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 3 · 2023: 3 · 2022: 6 · 2021: 8 · 2020: 4 · 2019: 5 · 2018: 5 · 2017: 9 · 2016: 10 · 2015: 6 · 2014: 3
- FWCI
- 0.93
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Neuroscience Research (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Growth Hormone and Insulin-like Growth Factors
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Nerve injury and regeneration
- Health Sciences › Medicine › Neurology › Traumatic Brain Injury and Neurovascular Disturbances
- Keywords
- growth hormone, neuroprotection, nerve regeneration, neurological disorders, brain injury, neuronal differentiation, neurotransmitters, brain development, neurological recovery
- MeSH terms
- Animals, Brain Injuries, Cognition, Humans, Nerve Regeneration, Neurons, Growth Hormone, Neuroprotective Agents
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review