The DOI matches its Crossref record; 63 of the 63 references it cites were found in a registry or an index.
Sleep deprivation reduces default mode network connectivity and anti-correlation during rest and task performance
Abstract
Sleep deprivation (SD) can alter extrinsic, task-related fMRI signal involved in attention, memory and executive function. However, its effects on intrinsic low-frequency connectivity within the Default Mode Network (DMN) and its related anti-correlated network (ACN) have not been well characterized. We investigated the effect of SD on functional connectivity within the DMN, and on DMN-ACN anti-correlation, both during the resting state and during performance of a visual attention task (VAT). 26 healthy participants underwent fMRI twice: once after a normal night of sleep in rested wakefulness (RW) and once following approximately 24h of total SD. A seed-based approach was used to examine pairwise correlations of low-frequency fMRI signal across different nodes in each state. SD was associated with significant selective reductions in DMN functional connectivity and DMN-ACN anti-correlation. This was congruent across resting state and VAT analyses, suggesting that SD induces a robust alteration in the intrinsic connectivity within and between these networks.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Both studies found that sleep deprivation reduced resting functional connectivity within the default mode network (DMN) and between DMN and its anticorrelated network”
From Circadian rhythms, sleep deprivation, and human performance (2013) · cites this paper as [254]
Citations
Cites
Control of goal-directed and stimulus-driven attention in the brain
Corbetta, M., & Shulman, G. L. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn755 · Cited by 12,881
A default mode of brain function
Raichle, M. E., MacLeod, A. M., Snyder, A. Z., Powers, W. J., Gusnard, D. A., & Shulman, G. L. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.2.676 · Cited by 12,190
Co-Planar Stereotaxic Atlas of the Human Brain
Talairach, J., & Tournoux, P. (1988) · Medical Entomology and Zoology · Cited by 11,798
The Brain's Default Network: Anatomy, Function, and Relevance to Disease
Buckner, R. L., Andrews‐Hanna, J. R., & Schacter, D. L. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1440.011 · Cited by 9,761
The human brain is intrinsically organized into dynamic, anticorrelated functional networks
Fox, M. D., Snyder, A. Z., Vincent, J. L., Corbetta, M., Van Essen, D. C., & Raichle, M. E. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504136102 · Cited by 8,553
Co-planar stereotaxic atlas of the human brain
Laitinen, L. (1989) · Clinical Neurology and Neurosurgery · doi:10.1016/0303-8467(89)90128-5 · Cited by 7,565
Dissociable intrinsic connectivity networks for salience processing and executive control
Seeley, W. W., Menon, V., Schatzberg, A. F., Keller, J., Glover, G. H., Kenna, H., Reiss, A. L., & Greicius, M. D. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.5587-06.2007 · Cited by 7,426
Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging
Fox, M. D., & Raichle, M. E. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2201 · Cited by 6,700
Neuronal Oscillations in Cortical Networks
Buzsáki, G., & Draguhn, A. (2004) · Science · doi:10.1126/science.1099745 · Cited by 6,576
Functional connectivity in the resting brain: a network analysis of the default mode hypothesis
Greicius, M. D., Krasnow, B., Reiss, A. L., & Menon, V. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0135058100 · Cited by 6,358
A self-assessment questionnaire to determine morningness- eveningness in human circadian rhythms
Home, J. K. (1976) · Medical Entomology and Zoology · Cited by 4,783
Binder, J. R., Desai, R. H., Graves, W. W., & Conant, L. L. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhp055 · Cited by 4,060
Forest before trees: The precedence of global features in visual perception
Navon, D. (1977) · Cognitive Psychology · doi:10.1016/0010-0285(77)90012-3 · Cited by 4,005
(1976) · PubMed · Cited by 3,979
Sridharan, D., Levitin, D. J., & Menon, V. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0800005105 · Cited by 2,892
Neurocognitive consequences of sleep deprivation
Goel, N., Rao, H., Durmer, J., & Dinges, D. (2009) · Seminars in Neurology · doi:10.1055/s-0029-1237117 · Cited by 2,154
Spontaneous neuronal activity distinguishes human dorsal and ventral attention systems
Fox, M. D., Corbetta, M., Snyder, A. Z., Vincent, J. L., & Raichle, M. E. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0604187103 · Cited by 2,101
Common blood flow changes across visual tasks: II. Decreases in cerebral cortex
Shulman, G. L., Fiez, J. A., Corbetta, M., Buckner, R. L., Miezin, F. M., Raichle, M. E., & Petersen, S. E. (1997) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.1997.9.5.648 · Cited by 1,890
Default-mode brain dysfunction in mental disorders: A systematic review
Broyd, S. J., Demanuele, C., Debener, S., Helps, S. K., James, C. J., & Sonuga-Barke, E. J. S. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.09.002 · Cited by 1,675
Disruption of Large-Scale Brain Systems in Advanced Aging
Andrews-Hanna, J. R., Snyder, A. Z., Vincent, J. L., Lustig, C., Head, D., Raichle, M. E., & Buckner, R. L. (2007) · Neuron · doi:10.1016/j.neuron.2007.10.038 · Cited by 1,592
The neural bases of momentary lapses in attention
Weissman, D. H., Roberts, K. C., Visscher, K. M., & Woldorff, M. G. (2006) · Nature Neuroscience · doi:10.1038/nn1727 · Cited by 1,566
Functional connectivity in single and multislice echoplanar imaging using resting-state fluctuations
Lowe, M. J., Mock, B. J., & Sorenson, J. A. (1998) · NeuroImage · doi:10.1006/nimg.1997.0315 · Cited by 1,394
Competition between functional brain networks mediates behavioral variability
Kelly, A. M. C., Uddin, L. Q., Biswal, B. B., Castellanos, F. X., & Milham, M. P. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2007.08.008 · Cited by 1,287
Deconstructing episodic memory with construction
Hassabis, D., & Maguire, E. A. (2007) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2007.05.001 · Cited by 1,229
Clinical applications of resting state functional connectivity
Fox, M. (2010) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2010.00019 · Cited by 1,219
Sleep Deprivation and Vigilant Attention
Lim, J., & Dinges, D. F. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1417.002 · Cited by 1,213
The proactive brain: using analogies and associations to generate predictions
Bar, M. (2007) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2007.05.005 · Cited by 1,144
Intrinsic Fluctuations within Cortical Systems Account for Intertrial Variability in Human Behavior
Fox, M., Snyder, A. Z., Vincent, J. L., & Raichle, M. E. (2007) · Neuron · doi:10.1016/j.neuron.2007.08.023 · Cited by 773
Decoupling of the brain's default mode network during deep sleep
Horovitz, S. G., Braun, A. R., Carr, W. S., Picchioni, D., Balkin, T. J., Fukunaga, M., & Duyn, J. H. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0901435106 · Cited by 685
Greicius, M. D., & Menon, V. (2004) · Journal of Cognitive Neuroscience · doi:10.1162/0898929042568532 · Cited by 684
Very Slow Activity Fluctuations in Monkey Visual Cortex: Implications for Functional Brain Imaging
Leopold, D. A. (2003) · Cerebral Cortex · doi:10.1093/cercor/13.4.422 · Cited by 675
Fox, M. D., Snyder, A. Z., Zacks, J. M., & Raichle, M. E. (2006) · Nature Neuroscience · doi:10.1038/nn1616 · Cited by 660
Boveroux, P., Vanhaudenhuyse, A., Bruno, M.-A., Noirhomme, Q., Lauwick, S., Luxen, A., Degueldre, C., Plenevaux, A., Schnakers, C., Phillips, C., et al. (2010) · Anesthesiology · doi:10.1097/aln.0b013e3181f697f5 · Cited by 630
Fair, D. A., Schlaggar, B. L., Cohen, A. L., Miezin, F. M., Dosenbach, N. U. F., Wenger, K. K., Fox, M., Snyder, A. Z., Raichle, M. E., & Petersen, S. E. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2006.11.051 · Cited by 615
How default is the default mode of brain function?
Fransson, P. (2006) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2006.06.017 · Cited by 611
Laird, A. R., Eickhoff, S. B., Li, K., Robin, D. A., Glahn, D. C., & Fox, P. T. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.4004-09.2009 · Cited by 561
Persistent default‐mode network connectivity during light sedation
Greicius, M. D., Kiviniemi, V. J., Tervonen, O. A., Vainionpää, V., Alahuhta, S., Reiss, A. L., & Menon, V. (2008) · Human Brain Mapping · doi:10.1002/hbm.20537 · Cited by 514
Functional Imaging of Working Memory after 24 Hr of Total Sleep Deprivation
Chee, M. W. L., & Choo, W. C. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.0007-04.2004 · Cited by 509
Self-citationSelf-referential reflective activity and its relationship with rest: a PET study
D’Argembeau, A., Collette, F., der Linden, M. V., Laureys, S., Fiore, G. D., Degueldre, C., Luxen, A., & Salmon, É. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2004.11.048 · Cited by 498
Neural foundations to moral reasoning and antisocial behavior.
Raine, A., & Yang, Y. (2006) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsl033 · Cited by 479
Lim, J., Wu, W., Wang, J., Detre, J. A., Dinges, D. F., & Rao, H. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.11.020 · Cited by 419
Development of the Brain's Default Mode Network from Wakefulness to Slow Wave Sleep
Sämann, P. G., Wehrle, R., Hoehn, D., Spoormaker, V. I., Peters, H., Tully, C., Holsboer, F., & Czisch, M. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhq295 · Cited by 399
Less effective executive functioning after one night's sleep deprivation
Nilsson, J., Söderström, M., KARLSSON, A. U., Lekander, M., Åkerstedt, T., Erixon-Lindroth, N., & Axelsson, J. (2005) · Journal of Sleep Research · doi:10.1111/j.1365-2869.2005.00442.x · Cited by 371
Consequences, Action, and Intention as Factors in Moral Judgments: An fMRI Investigation
Schaich Borg, J., Hynes, C., Van Horn, J., Grafton, S., & Sinnott-Armstrong, W. (2006) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2006.18.5.803 · Cited by 355
Lapsing during Sleep Deprivation Is Associated with Distributed Changes in Brain Activation
Chee, M. W. L., Tan, J. C., Zheng, H., Parimal, S., Weissman, D. H., Zagorodnov, V., & Dinges, D. F. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.0733-08.2008 · Cited by 293
Self-citationFunctional neuroimaging insights into how sleep and sleep deprivation affect memory and cognition
Chee, M. W. L., & Chuah, L. Y. M. (2008) · Current Opinion in Neurology · doi:10.1097/wco.0b013e3283052cf7 · Cited by 267
Self-citationRest-stimulus interaction in the brain: a review
Northoff, G., Qin, P., & Nakao, T. (2010) · Trends in Neurosciences · doi:10.1016/j.tins.2010.02.006 · Cited by 248
Esposito, F., Bertolino, A., Scarabino, T., Latorre, V., Blasi, G., Popolizio, T., Tedeschi, G., Cirillo, S., Goebel, R., & Salle, F. D. (2006) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2006.06.012 · Cited by 235
The effects of 53 hours of sleep deprivation on moral judgment
Killgore, W. D. S., Killgore, D. B., Day, L. M., Li, C., Kamimori, G. H., & Balkin, T. J. (2007) · SLEEP · doi:10.1093/sleep/30.3.345 · Cited by 225
Greater activation of the “default” brain regions predicts stop signal errors
Li, C. R., Yan, P., Bergquist, K. L., & Sinha, R. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.07.021 · Cited by 204
Choo, W.-C., Lee, W.-W., Venkatraman, V., Sheu, F.-S., & Chee, M. W. L. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2004.11.029 · Cited by 203
Self-citationImpairment of Attentional Networks after 1 Night of Sleep Deprivation
Tomasi, D. G., Wang, R. L., Telang, F., Boronikolas, V., Jayne, M. C., Wang, G., Fowler, J. S., & Volkow, N. D. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhn073 · Cited by 201
Sleep deprivation adversely affects interpersonal responses to frustration
Kahn-Greene, E. T., Lipizzi, E. L., Conrad, A. K., Kamimori, G. H., & Killgore, W. D. S. (2006) · Personality and Individual Differences · doi:10.1016/j.paid.2006.06.002 · Cited by 200
Arfanakis, K., Cordes, D., Haughton, V. M., Moritz, C. H., Quigley, M. A., & Meyerand, M. E. (2000) · Magnetic Resonance Imaging · doi:10.1016/s0730-725x(00)00190-9 · Cited by 191
Chee, M. W. L., & Chuah, Y. M. L. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610712104 · Cited by 172
Self-citationIncreased sleep pressure reduces resting state functional connectivity
Sämann, P. G., Tully, C., Spoormaker, V. I., Wetter, T. C., Holsboer, F., Wehrle, R., & Czisch, M. (2010) · Magnetic Resonance Materials in Physics Biology and Medicine · doi:10.1007/s10334-010-0213-z · Cited by 157
The Unrested Resting Brain: Sleep Deprivation Alters Activity within the Default-mode Network
Gujar, N., Yoo, S., Hu, P. T., & Walker, M. P. (2009) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2009.21331 · Cited by 156
Caldwell, J. A., Prazinko, B., & Caldwell, J. L. (2003) · Clinical Neurophysiology · doi:10.1016/s1388-2457(02)00283-3 · Cited by 150 · cited 1×
“This comparison is important in SD studies because sleepiness increases in the supine position (Caldwell et al., 2003) and is expected to be accentuated following sleep deprivation, particularly in the absence of task performance.”
BackgroundImproved Detection of Event-Related Functional MRI Signals Using Probability Functions
Hagberg, G. E., Zito, G., Patria, F., & Sanes, J. N. (2001) · NeuroImage · doi:10.1006/nimg.2001.0880 · Cited by 103
Acute dissociation after 1 night of sleep loss.
Giesbrecht, T., Smeets, T., Leppink, J., Jelícic, M., & Merckelbach, H. L. G. J. (2007) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.116.3.599 · Cited by 101
Altered local coherence in the default mode network due to sevoflurane anesthesia
Deshpande, G., Kerssens, C., Sebel, P. S., & Hu, X. P. (2010) · Brain Research · doi:10.1016/j.brainres.2009.12.075 · Cited by 88
Esposito, F., Aragri, A., Latorre, V., Popolizio, T., Scarabino, T., Cirillo, S., Marciano, E., Tedeschi, G., & Salle, F. D. (2009) · PubMed · Cited by 82
Where is your shoulder? Neural correlates of localizing others’ body parts
Félician, O., Anton, J., Nazarian, B., Roth, M., Roll, J., & Romaiguère, P. (2009) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2009.03.001 · Cited by 27
Flagged first, then by citations
Cited by
Sorted by citations
The sleep-deprived human brain
Krause, A. J., Simon, E. B., Mander, B. A., Greer, S. M., Saletin, J. M., Goldstein-Piekarski, A. N., & Walker, M. P. (2017) · Nature Reviews Neuroscience · doi:10.1038/nrn.2017.55 · Cited by 1,200
Large-scale brain systems in ADHD: beyond the prefrontal–striatal model
Castellanos, F. X., & Proal, E. (2012) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2011.11.007 · Cited by 831
Memory loss in Alzheimer's disease
Jahn, H. (2013) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2013.15.4/hjahn · Cited by 653
Circadian rhythms, sleep deprivation, and human performance
Goel, N., Basner, M., Rao, H., & Dinges, D. F. (2013) · Progress in Molecular Biology and Translational Science · doi:10.1016/b978-0-12-396971-2.00007-5 · Cited by 400
“Two recent studies have used FC-fMRI to investigate the effect of one night of either total or partial sleep deprivation on functional connectivity.(253,254) Both studies found that sleep deprivation reduced”
Sleep deprivation, vigilant attention, and brain function: a review
Hudson, A. N., Dongen, H. P. A. V., & Honn, K. A. (2019) · Neuropsychopharmacology · doi:10.1038/s41386-019-0432-6 · Cited by 426
Metadata
- Authors
- De Havas, J. A., Parimal, S., Soon, C. S., & Chee, M. W. L.
- Affiliations
- National University of Singapore (SG)
- Corresponding author
- Chee, Michael W.L.
- Venue
- NeuroImage
- Publisher
- Elsevier BV
- Published
- 2012-01
- Volume
- 59
- Issue
- 2
- Pages
- 1745-1751
- ISSN
- 1053-8119 (ISSN-L)
- OpenAlex
- W2102436032
- Cited by
- 363
- References
- 63
- Citations by year
- 2026: 24 · 2025: 17 · 2024: 21 · 2023: 18 · 2022: 27 · 2021: 27 · 2020: 25 · 2019: 27 · 2018: 34 · 2017: 33 · 2016: 23 · 2015: 29 · 2014: 19 · 2013: 30 · 2012: 7
- FWCI
- 9.26
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- NeuroImage (publishedVersion)
- PubMed (publishedVersion)
- National University of Singapore (submittedVersion)
- Funders
- Defense Science and Technology Agency Singapore (POD0713897)
- National Research Foundation Singapore
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Keywords
- sleep deprivation, default mode network, functional connectivity, resting state, intrinsic brain connectivity, seed-based correlation analysis
- MeSH terms
- Attention, Brain, Female, Humans, Magnetic Resonance Imaging, Male, Nerve Net, Rest, Sleep Deprivation, Statistics as Topic, Task Performance and Analysis, Visual Perception, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
