The Science of Stroke: Mechanisms in Search of Treatments

Moskowitz, Michael A., Lo, Eng H., Iadecola, Costantino·2010·Neuron

DOI 10.1016/j.neuron.2010.07.002

Cited by (1,002)

Items 401–500 of 1,002

Activation of Wnt/Beta-Catenin Signaling Pathway as a Promising Therapeutic Candidate for Cerebral Ischemia/Reperfusion Injury
Zhizhun Mo, Zhongyi Zeng, Yuxiang Liu, Linsheng Zeng, Jiansong Fang, Yinzhong Ma · 2022 · Frontiers in Pharmacology
Ellagic Acid and Its Anti-Aging Effects on Central Nervous System
Heyu Zhu, Yuanmei Yan, Yi Jiang, Xianfang Meng · 2022 · International Journal of Molecular Sciences
Targeting PI3K/Akt in Cerebral Ischemia Reperfusion Injury Alleviation: From Signaling Networks to Targeted Therapy
Ting Zheng, Taotao Jiang, Hongxiang Ma, Yanping Zhu, M.Y. Wang · 2024 · Molecular Neurobiology
The inhibitory effect of S‐nitrosoglutathione on blood–brain barrier disruption and peroxynitrite formation in a rat model of experimental stroke
Mushfiquddin Khan, Tajinder S. Dhammu, Harutoshi Sakakima, Anadakumar Shunmugavel, Anne Genevieve Gilg, Avtar Kaur Singh, Inderjit Singh · 2012 · Journal of Neurochemistry
Vascular cognitive impairment and Alzheimer’s disease: role of cerebral hypoperfusion and oxidative stress
Hyun Ah Kim, Alyson A. Miller, Grant Raymond Drummond, Amanda Gay Thrift, Thiruma Valavan Arumugam, Thanh G. Phan, Velandai K. Srikanth, Christopher Graeme Sobey · 2012 · Naunyn-Schmiedeberg s Archives of Pharmacology
Neuroprotection and Disease Modification by Astrocytes and Microglia in Parkinson Disease
Shinichi Takahashi, Kyoko Mashima · 2022 · Antioxidants
Myeloid-derived MIF drives RIPK1-mediated cerebromicrovascular endothelial cell death to exacerbate ischemic brain injury
Yan Li, Chengyu Zou, Chen Chen, Sixuan Li, Ziyu Zhu, Qiuyue Fan, Rui Pang, Fengshi Li, Zengai Chen, Zhenghong Wang et al. · 2023 · Proceedings of the National Academy of Sciences
A Functional Requirement for Astroglia in Promoting Blood Vessel Development in the Early Postnatal Brain
Shang Ma, Hyo Jun Kwon, Zhen Huang · 2012 · PLoS ONE
NADPH Oxidase: A Potential Target for Treatment of Stroke
Li Zhang, Jie Wu, Xiaochun Duan, Xiaodi Tian, Haitao Shen, Qing Sun, Gang Chen · 2016 · Oxidative Medicine and Cellular Longevity
Function of neural stem cells in ischemic brain repair processes
Ruilan Zhang, Zhenggang Zhang, Michael Chopp · 2016 · Journal of Cerebral Blood Flow & Metabolism
Therapeutic Potential of Annexin A1 in Ischemia Reperfusion Injury
Junaid Ansari, Gaganpreet Kaur, Felicity N. E. Gavins · 2018 · International Journal of Molecular Sciences
PPAR-γ Ameliorates Neuronal Apoptosis and Ischemic Brain Injury via Suppressing NF-κB-Driven p22phox Transcription
Jui‐Sheng Wu, Hsin Da Tsai, Wai-Mui Cheung, Chung Y. Hsu, Teng‐Nan Lin · 2015 · Molecular Neurobiology
Role of Perivascular Oligodendrocyte Precursor Cells in Angiogenesis After Brain Ischemia
Natsue Kishida, Takakuni Maki, Yasushi Takagi, Ken Yasuda, Hisanori Kinoshita, Takashi Ayaki, Takayuki Noro, Yusuke Kinoshita, Yūichi Ono, Hiroharu Kataoka et al. · 2019 · Journal of the American Heart Association
Survivin Is a Transcriptional Target of STAT3 Critical to Estradiol Neuroprotection in Global Ischemia
Yoshihide Sehara, Kirsty Sawicka, Jee-Yeon Hwang, Adrianna Latuszek-Barrantes, Anne M. Etgen, Ruth Suzanne Zukin · 2013 · Journal of Neuroscience
A Critical Role for Interferon Regulatory Factor 9 in Cerebral Ischemic Stroke
Hou‐Zao Chen, Sen Guo, Zuo-Zhi Li, Yanyun Lu, Ding-Sheng Jiang, Ran Zhang, Hao Chuan Lei, Lu Gao, Xiaofei Zhang, Yan Zhang et al. · 2014 · Journal of Neuroscience
IP3, a small molecule with a powerful message
Elke Decrock, Marijke De Bock, Nan Wang, Ashish Kumar Gadicherla, Mélissa Bol, Tinneke Delvaeye, Peter Vandenabeele, Mathieu Vinken, Geert Bultynck, Dmitri V. Krysko et al. · 2013 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Sphingosine Kinase 2 Mediates Cerebral Preconditioning and Protects the Mouse Brain Against Ischemic Injury
Lai‐Ming Yung, Ying Wei, Tao Qin, Yumei Wang, Charles D. Smith, Christian Waeber · 2011 · Stroke
Lentivirus-mediated overexpression of OTULIN ameliorates microglia activation and neuroinflammation by depressing the activation of the NF-κB signaling pathway in cerebral ischemia/reperfusion rats
Hongbei Xu, Wenyi Qin, Hu Xiao, Song Mu, Jun Zhu, Wenhao Lu, Yong Luo · 2018 · Journal of Neuroinflammation
Liposomes for drug delivery in stroke
Gisele Eva Bruch, Lorena Figueiredo Fernandes, Beatriz Lopes Tecedor Bassi, Marco Túllio Rodrigues Alves, Isabelle O. Pereira, Fréderic Frézard, André Ricardo Massensini · 2019 · Brain Research Bulletin
Hypoxia Inducible Factor-1α binds and activates γ-secretase for Aβ production under hypoxia and cerebral hypoperfusion
Alexander, Courtney, Li, Thomas, Hattori, Yorito, Chiu, Danica, Frost, Georgia R., Jonas, Lauren, Liu, Chenge, Anderson, Corey J., Wong, Eitan, Park, Laibaik et al. · 2022 · Molecular Psychiatry
Micro‐RNA‐30a regulates ischemia‐induced cell death by targeting heat shock protein HSPA5 in primary cultured cortical neurons and mouse brain after stroke
Peng Wang, Nan Zhang, Jia Liang, Jiefei Li, Song Han, Junfa Li · 2015 · Journal of Neuroscience Research
Roles of Pericytes in Stroke Pathogenesis
Jyoti Gautam, Yao Yao · 2018 · Cell Transplantation
The Innate Immune System After Ischemic Injury
Gabriel Courties, Michael A. Moskowitz, Matthias Nahrendorf · 2013 · JAMA Neurology
Roles for HIF-1α in neural stem cell function and the regenerative response to stroke
Lee Anna Cunningham, Kate M. Candelario, Lu Li · 2011 · Behavioural Brain Research
Necroptosis: Who Knew There were so Many Interesting Ways to Die?
S. M. Fayaz, V. S. Suvanish Kumar, Golgodu Krishnamurthy Rajanikant · 2014 · CNS & Neurological Disorders - Drug Targets
Reverse NCX Attenuates Cellular Sodium Loading in Metabolically Compromised Cortex
Niklas J. Gerkau, Cordula Rakers, Simone Durry, Gabor C. Petzold, Christine R. Rose · 2017 · Cerebral Cortex
Rosmarinic Acid Mitigates Lipopolysaccharide-Induced Neuroinflammatory Responses through the Inhibition of TLR4 and CD14 Expression and NF-κB and NLRP3 Inflammasome Activation
Yicong Wei, Jian‐Xiong Chen, Yonghong Hu, Wei Lu, Xiaoqin Zhang, Ruiguo Wang, Kedan Chu · 2018 · Inflammation
Silencing of Long Non-coding RNA GAS5 Suppresses Neuron Cell Apoptosis and Nerve Injury in Ischemic Stroke Through Inhibiting DNMT3B-Dependent MAP4K4 Methylation
Yiming Deng, Duanduan Chen, Feng Gao, Hong Lv, Guojun Zhang, Xuan Sun, Lian Liu, Dapeng Mo, Ning Ma, Ligang Song et al. · 2020 · Translational Stroke Research
Blocking a vicious cycle nNOS/peroxynitrite/AMPK by S-nitrosoglutathione: implication for stroke therapy
Mushfiquddin Khan, Tajinder S. Dhammu, Fumiyo Matsuda, Avtar Kaur Singh, Inderjit Singh · 2015 · BMC Neuroscience
Visualizing Oxidative Stress Level for Timely Assessment of Ischemic Stroke via a Ratiometric Near-Infrared-II Luminescent Nanoprobe
Meng Zhang, Zijun Wang, Caixia Wang, Yuting Wu, Zhen Li, Zhihong Liu · 2021 · ACS Nano
Gut Microbiota in Ischemic Stroke: Role of Gut Bacteria-Derived Metabolites
Wei Zhang, Xiao Yu Dong, Rui Huang · 2022 · Translational Stroke Research
Acidosis, Acid-Sensing Ion Channels, and Neuronal Cell Death
Yizhi Wang, Tian‐Le Xu · 2011 · Molecular Neurobiology
Neuroprotection targeting ischemic penumbra and beyond for the treatment of ischemic stroke
Ran Liu, Hui Yuan, Fang Yuan, Shao‐Hua Yang · 2012 · Neurological Research
Neuroprotective effects of (−)-linalool against oxygen-glucose deprivation-induced neuronal injury
Hyeon Hwan Park, Geun Hee Seol, Sangwoo Ryu, In-Young Choi · 2016 · Archives of Pharmacal Research
Nrf2 promotes reparative angiogenesis through regulation of NADPH oxidase-2 in oxygen-induced retinopathy
Yanhong Wei, Junsong Gong, Zhenhua Xu, Elia J. Duh · 2016 · Free Radical Biology and Medicine
Down-regulation of microRNA-142-5p attenuates oxygen-glucose deprivation and reoxygenation-induced neuron injury through up-regulating Nrf2/ARE signaling pathway
Ning Wang, Lingmin Zhang, Yang Lu, Mingxin Zhang, Zhenni Zhang, Kui Wang, Jianrui Lv · 2017 · Biomedicine & Pharmacotherapy
Early Reperfusion After Brain Ischemia Has Beneficial Effects Beyond Rescuing Neurons
Masaki Tachibana, Tetsuro Ago, Yoshinobu Wakisaka, Junya Kuroda, Masahiro Shijo, Yoji Yoshikawa, Motohiro Komori, Ataru Nishimura, Noriko Makihara, Kuniyuki Nakamura et al. · 2017 · Stroke
Nampt/PBEF/Visfatin Exerts Neuroprotective Effects Against Ischemia/Reperfusion Injury via Modulation of Bax/Bcl-2 Ratio and Prevention of Caspase-3 Activation
Sohaila Erfani, Mehdi Khaksari, Shahrbanoo Oryan, Nabi Shamsaei, Nahid Aboutaleb, Farnaz Nikbakht · 2015 · Journal of Molecular Neuroscience
Treadmill exercise promotes neurogenesis and myelin repair via upregulating Wnt/β‑catenin signaling pathways in the juvenile brain following focal cerebral ischemia/reperfusion
Jing‐Yan Cheng, Weimin Shen, Lingqin Jin, Juanjuan Pan, Yan Zhou, Guoyuan Pan, Qingfeng Xie, Quan Hu, Shamin Wu, Hongmei Zhang et al. · 2020 · International Journal of Molecular Medicine
Enhancing stroke assessment simulation experience in clinical training using augmented reality
Ci‐Jyun Liang, Charles Start, Hanna Boley, Vineet R. Kamat, Carol C. Menassa, Michelle Aebersold · 2020 · Virtual Reality
Imbalance between IL-17A-Producing Cells and Regulatory T Cells during Ischemic Stroke
Yuehua Hu, Yanhua Zheng, Ya Wu, Bing Ni, Shugui Shi · 2014 · Mediators of Inflammation
Translational MR Neuroimaging of Stroke and Recovery
Emiri T. Mandeville, Cenk Ayata, Yi Zhou Zheng, Joseph B. Mandeville · 2016 · Translational Stroke Research
Cannabinoid Type-2 Receptor Drives Neurogenesis and Improves Functional Outcome After Stroke
Isabel Bravo‐Ferrer, María Isabel Cuartero, Juan Guillermo Zarruk, Jesus Miguel Pradillo, Olivia Hurtado, Víctor G. Romera, Javier Díaz-Alonso, Juan Manuel García-Segura, Manuel Guzmán, Ignacio Lizasoaín et al. · 2016 · Stroke
Brain ischemic preconditioning protects against ischemic injury and preserves the blood-brain barrier via oxidative signaling and Nrf2 activation
Tuo Yang, Yang Sun, Leilei Mao, Meijuan Zhang, Qianqian Li, Lili Zhang, Yejie Shi, Rehana K. Leak, Jun Chen, Feng Zhang · 2018 · Redox Biology
PLA2G2E-mediated lipid metabolism triggers brain-autonomous neural repair after ischemic stroke
Akari Nakamura, Seiichiro Sakai, Yoshitaka Taketomi, Jun Tsuyama, Yoshimi Miki, Yuichiro Hara, Nobutaka Arai, Yuki Sugiura, Hideya Kawaji, Makoto Murakami et al. · 2023 · Neuron
Qingda granule alleviates cerebral ischemia/reperfusion injury by inhibiting TLR4/NF-κB/NLRP3 signaling in microglia
Qiaoyan Cai, Chunyu Zhao, Yaoyao Xu, Haowei Lin, Beibei Jia, Bin Huang, Shan Lin, Daxin Chen, Peizhi Jia, Meiling Wang et al. · 2024 · Journal of Ethnopharmacology
In vivo Contributions of BH3-Only Proteins to Neuronal Death Following Seizures, Ischemia, and Traumatic Brain Injury
Tobías Engel, Nikolaus Plesnila, Jochen H.M. Prehn, David Clifford Henshall · 2011 · Journal of Cerebral Blood Flow & Metabolism
Participation of MCP-induced protein 1 in lipopolysaccharide preconditioning-induced ischemic stroke tolerance by regulating the expression of proinflammatory cytokines
Jian Liang, Jing Wang, Yasser Saad, Logan Warble, Edilu Becerra, Pappachan E. Kolattukudy · 2011 · Journal of Neuroinflammation
Resveratrol ameliorates oxidative stress and inhibits aquaporin 4 expression following rat cerebral ischemia-reperfusion injury
Weina Li, Changhong Tan, YI LIU, Xi Liu, XIN WANG, Yuejiang Gui, Qin Lu, Fen Deng, Zhen Yu, HU Chang-lin et al. · 2015 · Molecular Medicine Reports
Crosstalk of Astrocytes and Other Cells during Ischemic Stroke
Tingting He, Guo‐Yuan Yang, Zhijun Zhang · 2022 · Life
Estrogen plays an important role by influencing the NLRP3 inflammasome
Wanglin Dong, Qianwen Peng, Zhuoxin Liu, Zhenxing Xie, Xiajun Guo, Yuanyuan Li, Chaoran Chen · 2023 · Biomedicine & Pharmacotherapy
Neuroprotective effect of aquaporin-4 deficiency in a mouse model of severe global cerebral ischemia produced by transient 4-vessel occlusion
Gökhan Akdemir, Julien Ratelade, Nithi Asavapanumas, A.S. Verkman · 2014 · Neuroscience Letters
Experimental animal models and inflammatory cellular changes in cerebral ischemic and hemorrhagic stroke
Tao Yan, Michael Chopp, Jieli Chen · 2015 · Neuroscience Bulletin
Thomas Willis Lecture: Is Translational Stroke Research Broken, and if So, How Can We Fix It?
Dirnagl, Ulrich · 2016 · Stroke
Hydrogel Scaffolds: Towards Restitution of Ischemic Stroke-Injured Brain
Aswathi Gopalakrishnan, Sahadev A. Shankarappa, Golgodu Krishnamurthy Rajanikant · 2018 · Translational Stroke Research
Enhancement of Functionality and Therapeutic Efficacy of Cell-Based Therapy Using Mesenchymal Stem Cells for Cardiovascular Disease
Chul Won Yun, Sang Hun Lee · 2019 · International Journal of Molecular Sciences
LRG1 Promotes Apoptosis and Autophagy through the TGFβ-smad1/5 Signaling Pathway to Exacerbate Ischemia/Reperfusion Injury
Jing Jin, Hongxue Sun, Dan Liu, Haining Wang, Qingqing Liu, Hongping Chen, Di Zhong, Guozhong Li · 2019 · Neuroscience
Stimulation of functional recovery via the mechanisms of neurorepair by S-nitrosoglutathione and motor exercise in a rat model of transient cerebral ischemia and reperfusion
Harutoshi Sakakima, Mushfiquddin Khan, Tajinder S. Dhammu, Anandakumar Shunmugavel, Yoshihiro Yoshida, Inderjit Singh, Avtar Kaur Singh · 2012 · Restorative Neurology and Neuroscience
Quantitative Neuroproteomics of an In Vivo Rodent Model of Focal Cerebral Ischemia/Reperfusion Injury Reveals a Temporal Regulation of Novel Pathophysiological Molecular Markers
Arnab Datta, Jingru Qian, Tze Hsin Khor, Muh Tyng Teo, Klaus Heese, Siu Kwan Sze · 2011 · Journal of Proteome Research
AMP-Activated Protein Kinase (AMPK) and Energy-Sensing in the Brain
Santosh Ramamurthy, Gabriele V. Ronnett · 2012 · Experimental Neurobiology
Trasmembrane chemokines CX3CL1 and CXCL16 drive interplay between neurons, microglia and astrocytes to counteract pMCAO and excitotoxic neuronal death
Maria Rosito, Clotilde Lauro, Giuseppina Chece, Alessandra Porzia, Lucia Monaco, Fabrizio Mainiero, Myriam Catalano, Cristina Limatola, Flavia Trettel · 2014 · Frontiers in Cellular Neuroscience
Hydroxysafflor yellow A exerts neuroprotective effects in cerebral ischemia reperfusion-injured mice by suppressing the innate immune TLR4-inducing pathway
Yanni Lv, Yisong Qian, Longsheng Fu, Xuanying Chen, Haili Zhong, Xiaohua Wei · 2015 · European Journal of Pharmacology
Modulating Astrocyte Transition after Stroke to Promote Brain Rescue and Functional Recovery: Emerging Targets Include Rho Kinase
Hima C. S. Abeysinghe, Ellie Phillips, Heung Chin-Cheng, Philip M. Beart, Carli L. Roulston · 2016 · International Journal of Molecular Sciences
Inhibition of Histone Deacetylase 3 (HDAC3) Mediates Ischemic Preconditioning and Protects Cortical Neurons against Ischemia in Rats
Xiaoyu Yang, Qimei Wu, Lei Zhang, Linyin Feng · 2016 · Frontiers in Molecular Neuroscience
Reducing myeloperoxidase activity decreases inflammation and increases cellular protection in ischemic stroke
Hyeon J Kim, Ying Wei, Gregory R. Wojtkiewicz, Ji Yeon Lee, Michael A. Moskowitz, John W. Chen · 2018 · Journal of Cerebral Blood Flow & Metabolism
Pretreatment with Korean red ginseng or dimethyl fumarate attenuates reactive gliosis and confers sustained neuroprotection against cerebral hypoxic-ischemic damage by an Nrf2-dependent mechanism
Lei Liu, Mary K. Vollmer, Abdullah Shafique Ahmad, Victoria M. Fernandez, Hocheol Kim, Sylvain Doré · 2018 · Free Radical Biology and Medicine
Repurposing metformin to treat age-related neurodegenerative disorders and ischemic stroke
Sejal Sharma, Saeideh Nozohouri, Bhuvaneshwar Vaidya, Thomas J. Abbruscato · 2021 · Life Sciences
The Role of Sirt1 in Ischemic Stroke: Pathogenesis and Therapeutic Strategies
Junfang Zhang, Yulei Zhang, Yun‐Cheng Wu · 2018 · Frontiers in Neuroscience
Cathodal tDCS exerts neuroprotective effect in rat brain after acute ischemic stroke
Keying Zhang, Gang Rui, Junping Zhang, Ling T. Guo, Guangzhou An, Jiajin Lin, Wei He, Guirong Ding · 2020 · BMC Neuroscience
Sex differences in stroke outcome correspond to rapid and severe changes in gut permeability in adult Sprague-Dawley rats
Yumna El-Hakim, Kathiresh Kumar Mani, Amir Eldouh, Sivani Pandey, Maria T. Grimaldo, Alan R. Dabney, Rachel Pilla, Farida Sohrabji · 2021 · Biology of Sex Differences
Cellular Mechanisms Participating in Brain Repair of Adult Zebrafish and Mammals after Injury
Batoul Ghaddar, Luisa Lübke, David Couret, Sepand Rastegar, Nicolas Diotel · 2021 · Cells
Neural Stem Cells for Early Ischemic Stroke
Milton H. Hamblin, Jean‐Pyo Lee · 2021 · International Journal of Molecular Sciences
Alpha-linolenic acid: A promising nutraceutical for the prevention of stroke
Carine Nguemeni, Elsa Gouix, Miled Bourourou, Catherine Heurteaux, Nicolas Blondeau · 2013 · PharmaNutrition
High-mobility group box1 protein promotes neuroinflammation after intracerebral hemorrhage in rats
Chunyan Lei, Sen Lin, Chenze Zhang, Tao Wu, Wei Dong, Zilong Hao, M. Liu, Bo Wu · 2012 · Neuroscience
Blood-Brain Barrier: A Dual Life of MFSD2A?
Zhao, Zhen, Zlokovic, Berislav V. · 2014 · Neuron
Myeloperoxidase Inhibition Increases Neurogenesis after Ischemic Stroke
Hyeon-Ju Kim, Ying Wei, Ji Yong Lee, Yue Wu, Yi Zhou Zheng, Michael A. Moskowitz, John W. Chen · 2016 · Journal of Pharmacology and Experimental Therapeutics
Neutrophil-Biomimetic “Nanobuffer” for Remodeling the Microenvironment in the Infarct Core and Protecting Neurons in the Penumbra via Neutralization of Detrimental Factors to Treat Ischemic Stroke
Liu, Shanshan, Xu, Jianpei, Liu, Yipu, You, Yang, Xie, Laozhi, Tong, Shiqiang, Chen, Yu, Liang, Kaifan, Zhou, Songlei, Li, Fengan et al. · 2022 · ACS Applied Materials & Interfaces
CTRP3 Activates the AMPK/SIRT1-PGC-1α Pathway to Protect Mitochondrial Biogenesis and Functions in Cerebral Ischemic Stroke
Jianfei Gao, Tingting Qian, Wei Wang · 2020 · Neurochemical Research
Vascular pathology and pathogenesis of cognitive impairment and dementia in older adults
Sonal Agrawal, Julie A. Schneider · 2022 · Cerebral Circulation - Cognition and Behavior
Self-healing hydrogel as an injectable implant: translation in brain diseases
Junpeng Xu, Shan‐hui Hsu · 2023 · Journal of Biomedical Science
Cerebral endothelial derived vascular endothelial growth factor promotes the migration but not the proliferation of oligodendrocyte precursor cells in vitro
Kazuhide Hayakawa, Ji Hae Seo, Loc−Duyen D. Pham, Nobukazu Miyamoto, Angel T. Som, Shuzhen Guo, Kyu‐Won Kim, Eng H. Lo, Ken Arai · 2012 · Neuroscience Letters
Fullerenols and glucosamine fullerenes reduce infarct volume and cerebral inflammation after ischemic stroke in normotensive and hypertensive rats
Felix Fluri, Dan Grünstein, Ertugrul Cam, Udo Ungethuem, Florian Hatz, Juliane Schäfer, Samuel Samnick, Ina Israel, Christoph Kleinschnitz, Guillermo Orts‐Gil et al. · 2015 · Experimental Neurology
A Systematic Review and Meta-Analysis of Buyang Huanwu Decoction in Animal Model of Focal Cerebral Ischemia
Ruili Wei, Hai-juan Teng, Bo Yin, Yang Xu, Yue Du, Fang-pin He, Ketan Chu, Benyan Luo, Guo‐qing Zheng · 2013 · Evidence-based Complementary and Alternative Medicine
Honokiol protects brain against ischemia–reperfusion injury in rats through disrupting PSD95–nNOS interaction
Zhenyu Hu, Xiling Bian, Xiaoyan Liu, Yuanjun Zhu, Xiaoyi Zhang, Shizhong Chen, KeWei Wang, Yinye Wang · 2012 · Brain Research
MicroRNA-1906, a Novel Regulator of Toll-Like Receptor 4, Ameliorates Ischemic Injury after Experimental Stroke in Mice
Xiaomeng Xu, Zhuoyu Wen, Nan Zhao, Xiaohui Xu, Fang Wang, Jie Gao, Yongjun Jiang, Xinfeng Liu · 2017 · Journal of Neuroscience
Puerarin partly counteracts the inflammatory response after cerebral ischemia/reperfusion via activating the cholinergic anti-inflammatory pathway.
Xiaojie Liu, Zhigang Mei, Jingping Qian, Yongbao Zeng, Mingzhi Wang · 2013 · PubMed Central
Elovanoids are a novel class of homeostatic lipid mediators that protect neural cell integrity upon injury
Bhattacharjee, Surjyadipta, Jun, Bokkyoo, Belayev, Ludmila, Heap, Jessica, Kautzmann, Marie-Audrey, Obenaus, Andre, Menghani, Hemant, Marcell, Shawn J., Khoutorova, Larissa, Yang, Rong et al. · 2017 · Science Advances
Signaling pathways in brain ischemia: Mechanisms and therapeutic implications
Wen Lin, Xiaosu Zhao, Jiawen Cheng, Litao Li, Quan Jiang, Yixuan Zhang, Feng Han · 2023 · Pharmacology & Therapeutics
Magnolol protects neurons against ischemia injury via the downregulation of p38/MAPK, CHOP and nitrotyrosine
Jiann‐Hwa Chen, Hsing‐Chun Kuo, Kam-Fai Lee, Tung‐Hu Tsai · 2014 · Toxicology and Applied Pharmacology
Cofilin as a Promising Therapeutic Target for Ischemic and Hemorrhagic Stroke
Qasim Alhadidi, Muhammad Shahdaat Bin Sayeed, Zahoor A. Shah · 2015 · Translational Stroke Research
Buyang Huanwu Decoction ameliorates ischemic stroke by modulating multiple targets with multiple components: In vitro evidences
Weiwei Zhang, Feng Xu, Ding Wang, Jia Ye, Shao‐Qing Cai · 2018 · Chinese Journal of Natural Medicines
Hes1 Knockdown Exacerbates Ischemic Stroke Following tMCAO by Increasing ER Stress-Dependent Apoptosis via the PERK/eIF2α/ATF4/CHOP Signaling Pathway
Yueyong Li, Yingjun Zhang, Huangde Fu, Huadong Huang, Qifeng Lu, Houji Qin, Yingning Wu, Huatuo Huang, Guizhen Mao, Zhongheng Wei et al. · 2019 · Neuroscience Bulletin
The Heart-Brain Connection: A Multidisciplinary Approach Targeting a Missing Link in the Pathophysiology of Vascular Cognitive Impairment
Mark A. van Buchem, Geert Jan Biessels, Hans‐Peter Brunner‐La Rocca, Anton J.M. de Craen, Wiesje M. van der Flier, M. Arfan Ikram, Laurens Jaap Kappelle, Peter J. Koudstaal, Simon P. Mooijaart, Wiro J. Niessen et al. · 2014 · Journal of Alzheimer s Disease
Exosomes Treatment Mitigates Ischemic Brain Damage but Does Not Improve PostStroke Neurological Outcome
Koteswara Rao Nalamolu, Ishwarya Venkatesh, Adithya Mohandass, Jeffrey D. Klopfenstein, David M. Pinson, David Z. Wang, Krishna Kumar Veeravalli · 2019 · Cellular Physiology and Biochemistry
Neovascularization and functional recovery after intracerebral hemorrhage is conditioned by the Tp53 Arg72Pro single-nucleotide polymorphism
Cristina Rodríguez, Tomás Sobrino, Jesús Agulla, Verónica Bobo-Jiménez, María E. Ramos-Araque, Juan J Duarte, José Carlos Gómez Sánchez, Juan Pedro Bolaños, José Castillo, Ángeles Almeida · 2016 · Cell Death and Differentiation
Gasdermin Family: a Promising Therapeutic Target for Stroke
Sheng Chen, Shuhao Mei, Yujie Luo, Hemmings Wu, Jianmin Zhang, Junming Zhu · 2018 · Translational Stroke Research
Pharmacological Stimulation of Mitochondrial Biogenesis Using the Food and Drug Administration-Approved β 2 -Adrenoreceptor Agonist Formoterol for the Treatment of Spinal Cord Injury
Natalie E. Scholpa, Hannah C. Williams, Wenxue Wang, Daniel G. Corum, Aarti Narang, Stephen Tomlinson, Patrick G. Sullivan, Alexander G. Rabchevsky, Rick G. Schnellmann · 2018 · Journal of Neurotrauma
Inhibition of Connexin 43 Hemichannels Alleviates Cerebral Ischemia/Reperfusion Injury via the TLR4 Signaling Pathway
Yingzhu Chen, Liangzhu Wang, Lingling Zhang, Beilei Chen, Yang Liu, Xiaobo Li, Yuping Li, Hailong Yu · 2018 · Frontiers in Cellular Neuroscience
Lysophosphatidic acid receptor 1 (LPA1) plays critical roles in microglial activation and brain damage after transient focal cerebral ischemia
Bhakta Prasad Gaire, Arjun Sapkota, Mi‐Ryoung Song, Ji Woong Choi · 2019 · Journal of Neuroinflammation
Hemorrhagic Transformation After Tissue Plasminogen Activator Treatment in Acute Ischemic Stroke
Chengli Liu, Jie Xie, Shanshan Sun, Hui Li, Tianyu Li, Chao Qiang Jiang, Xuemei Chen, Junmin Wang, Anh Le, Jiarui Wang et al. · 2020 · Cellular and Molecular Neurobiology