The DOI matches its Crossref record; 60 of the 60 references it cites were found in a registry or an index.
Functional Architecture of an Optic Flow-Responsive Area that Drives Horizontal Eye Movements in Zebrafish
Open accessAbstract
Animals respond to whole-field visual motion with compensatory eye and body movements in order to stabilize both their gaze and position with respect to their surroundings. In zebrafish, rotational stimuli need to be distinguished from translational stimuli to drive the optokinetic and the optomotor responses, respectively. Here, we systematically characterize the neural circuits responsible for these operations using a combination of optogenetic manipulation and in vivo calcium imaging during optic flow stimulation. By recording the activity of thousands of neurons within the area pretectalis (APT), we find four bilateral pairs of clusters that process horizontal whole-field motion and functionally classify eleven prominent neuron types with highly selective response profiles. APT neurons are prevalently direction selective, either monocularly or binocularly driven, and hierarchically organized to distinguish between rotational and translational optic flow. Our data predict a wiring diagram of a neural circuit tailored to drive behavior that compensates for self-motion.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“recently identified as involved in processing whole-field motion in zebrafish (Kubo et al., 2014; Portugues et al., 2014).”
From Neural control and modulation of swimming speed in the larval zebrafish (2014) · cites this paper as Kubo et al., 2014
The cited source says what the claim attributes to it.
In the citing paper
“Benefitting from detailed experimental data (25, 29–34) and recent advances in physics simulation technologies (35), our open-source simZFish faithfully reproduces the zebrafish OMR, utilizing experimentally observed neural activity (25).”
From Artificial embodied circuits uncover neural architectures of vertebrate visuomotor behaviors (2025) · cites this paper as [33]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A Global Geometric Framework for Nonlinear Dimensionality Reduction
Tenenbaum, J. B., Silva, V. D., & Langford, J. C. (2000) · Science · doi:10.1126/science.290.5500.2319 · Cited by 13,585
Whole-brain functional imaging at cellular resolution using light-sheet microscopy
Ahrens, M. B., Orger, M. B., Robson, D. N., Li, J. M., & Keller, P. J. (2013) · Nature Methods · doi:10.1038/nmeth.2434 · Cited by 1,392
Optimization of a GCaMP Calcium Indicator for Neural Activity Imaging
Akerboom, J., Chen, T., Wardill, T. J., Tian, L., Marvin, J. S., Mutlu, S., Calderón, N. C., Esposti, F., Borghuis, B. G., Sun, X. R., et al. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.2601-12.2012 · Cited by 1,289
Self-citationForebrain gene expression domains and the evolving prosomeric model
Puelles, L., & Rubenstein, J. L. R. (2003) · Trends in Neurosciences · doi:10.1016/s0166-2236(03)00234-0 · Cited by 734
Higashijima, S., Hotta, Y., & Okamoto, H. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-01-00206.2000 · Cited by 562
A behavioral screen for isolating zebrafish mutants with visual system defects.
Brockerhoff, S. E., Hurley, J. B., Janssen‐Bienhold, U., Neuhauss, S. C. F., Driever, W., & Dowling, J. E. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.23.10545 · Cited by 481
Self-citationSelective Sensitivity to Direction of Movement in Ganglion Cells of the Rabbit Retina
Barlow, H. B., & Hill, R. M. (1963) · Science · doi:10.1126/science.139.3553.412 · Cited by 435
Genetic disorders of vision revealed by a behavioral screen of 400 essential loci in zebrafish
Neuhauss, S. C. F., Biehlmaier, O., Seeliger, M. W., Das, T., Kohler, K., Harris, W. A., & Baier, H. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-19-08603.1999 · Cited by 414
Self-citationThe accessory optic system of rabbit. II. Spatial organization of direction selectivity
Simpson, J. I., Leonard, C. S., & Soodak, R. E. (1988) · Journal of Neurophysiology · doi:10.1152/jn.1988.60.6.2055 · Cited by 333
Direction selectivity in the retina: symmetry and asymmetry in structure and function
Vaney, D. I., Sivyer, B., & Taylor, W. R. (2012) · Nature reviews. Neuroscience · doi:10.1038/nrn3165 · Cited by 330
Flagged first, then by citations
Cited by
Sorted by citations
Items 101–182 of 182
Boulanger-Weill, J., Kämpf, F., Schuhknecht, G. F. P., Schalek, R. L., Garza, R., Petkova, M. D., Vohra, S. K., Wu, Y., Savaliya, J. H., Tiller, R., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.03.14.643363 · Cited by 10
“A prime example of such a lack of topographic representation is the zebrafish pretectum, where binocular and monocular neurons are intermingled (Kubo et al. , 2014a; Naumann et al. , 2016).”
Visuomotor decision-making through multifeature convergence in the larval zebrafish hindbrain
Slangewal, K., Aimon, S., Capelle, M. Q., Kämpf, F., Naumann, H., Slanchev, K., Baier, H., & Bahl, A. (2026) · Nature Communications · doi:10.1038/s41467-026-69633-4 · Cited by 12
Self-citationDifferent ways of evolving tool-using brains in teleosts and amniotes
Estienne, P., Simion, M., Hagio, H., Yamamoto, N., Jenett, A., & Yamamoto, K. (2024) · Communications Biology · doi:10.1038/s42003-023-05663-8 · Cited by 9
“The major connectivity of the IL of other fish like trout, Astyanax surface fish, and zebrafish is with the PT, which is involved in stereotyped movements such as the optokinetic response (Kubo et al., 2014; Portugues et al., 2014) or the prey detection J-turn in larval zebrafish (Fajardo et al.”
BackgroundGenetic and Neurological Deficiencies in the Visual System of mct8 Mutant Zebrafish
Rozenblat, R., Tovin, A., Zada, D., Lebenthal-Loinger, I., Lerer‐Goldshtein, T., & Appelbaum, L. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23052464 · Cited by 9
Visual odometry of Rhinecanthus aculeatus depends on the visual density of the environment
Karlsson, C., Willis, J. K., Patel, M., & de Perera, T. B. (2022) · Communications Biology · doi:10.1038/s42003-022-03925-5 · Cited by 9
Artificial embodied circuits uncover neural architectures of vertebrate visuomotor behaviors
Liu, X., Loring, M. D., Zunino, L., Fouke, K. E., Longchamp, F. A., Bernardino, A., Ijspeert, A. J., & Naumann, E. A. (2025) · Science Robotics · doi:10.1126/scirobotics.adv4408 · Cited by 8
Correlating Whole Brain Neural Activity with Behavior in Head-Fixed Larval Zebrafish
Orger, M. B., & Portugues, R. (2016) · Methods in molecular biology · doi:10.1007/978-1-4939-3771-4_21 · Cited by 9
Fourier Motion Processing in the Optic Tectum and Pretectum of the Zebrafish Larva
Duchemin, A., Privat, M., & Sumbre, G. (2022) · Frontiers in Neural Circuits · doi:10.3389/fncir.2021.814128 · Cited by 8
“It has been shown that the pretectum is necessary and sufficient for the OKR (Kubo et al., 2014).”
BackgroundResultInfluentialSparse coding predicts optic flow specificities of zebrafish pretectal neurons
Ecke, G. A., Bruijns, S. A., Hölscher, J., Mikulasch, F. A., Witschel, T., Arrenberg, A. B., & Mallot, H. A. (2019) · Neural Computing and Applications · doi:10.1007/s00521-019-04500-6 · Cited by 8
“The whitened sparse coding approach yields the interesting results in terms of egomotion recovery but does not reflect the properties of zebrafish APT neurons.”
BackgroundMethodInfluentialSelf-citationRobles, E. (2017) · Journal of Neurogenetics · doi:10.1080/01677063.2017.1359834 · Cited by 7
Reduction of visual stimulus artifacts using a spherical tank for small, aquatic animals
Wang, K., Arrenberg, B., Hinz, J., & Arrenberg, A. B. (2021) · Scientific Reports · doi:10.1038/s41598-021-81904-2 · Cited by 7
Self-citationSeparate brainstem circuits for fast steering and slow exploratory turns
Xu, L., Zhu, B., Zhu, Z., Tao, X., Zhang, T., Manira, A. E., & Song, J. (2025) · Nature Communications · doi:10.1038/s41467-025-58621-9 · Cited by 6
“A sub-set of neurons in the pretectum that serve as direction-translation neurons, receiving synaptic inputs from direction-selective retinal ganglion cells (RGCs) that detect the visual fl ow 33,34,36,37,50,51,61,62 .”
Horstick, E. J., Tabor, K. M., Jordan, D. C., & Burgess, H. A. (2016) · Methods in molecular biology · doi:10.1007/978-1-4939-3771-4_25 · Cited by 6
Motor context coordinates visually guided walking in DrosophilaPreprint
Cruz, T. L., Fujiwara, T., Varela, N., Mohammad, F., Claridge‐Chang, A., & Chiappe, M. E. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/572792 · Cited by 7
“sensitive neurons are found universally across species, from insects to non-human primates, and exhibit large receptive fields selective for specific patterns of visual flow (Britto et al., 1981; Duffy and Wurtz, 1991; Grasse and Cynader, 1982; Hausen, 1982a; Hengstenberg et al., 1982; Joesch et al., 2008; Kano et al.…”
BackgroundA cerebellar internal model calibrates a feedback controller involved in sensorimotor controlPreprint
Markov, D. A., Petrucco, L., Kist, A. M., & Portugues, R. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.02.12.945956 · Cited by 6
Vertical optokinetic eye movements in the larval zebrafish
Burkhardt, D.-S., Möller, G., Deligand, L., Fichtner, C., Hladnik, T. C., & Arrenberg, A. B. (2026) · Journal of Experimental Biology · doi:10.1242/jeb.251770 · Cited by 5
“Both optokinetic and optomotor responses stabilize fish gaze and posture based on optic flow mediated self-motion estimation (Britten, 2008; Festl et al., 2012; Kubo et al., 2014; Wang et al., 2019, 2020; Warren and Hannon, 1988).”
Self-citationOn analogies in vertebrate and insect visual systems
Tanaka, R., & Portugues, R. (2025) · Nature reviews. Neuroscience · doi:10.1038/s41583-025-00932-3 · Cited by 5
“The eye movements triggered by optic flow are called the optokinetic reflex (OKR) or nystagmus (OKN) 112–115 , whereas body movements triggered by optic flow are called the opto-motor response (OMR) 115–117 .”
InfluentialZhang, Y., & Arrenberg, A. B. (2019) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2019.108366 · Cited by 5
Self-citationTsuda, S. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-817528-6.00017-6 · Cited by 5
Zebrafish Swimming into Neuroscience Research: A Visible Mind in A Transparent Brain
Shang, C., Mu, Y., & Du, J. (2015) · Scientia Sinica Vitae · doi:10.1360/n052014-00203 · Cited by 4
A brainstem integrator for self-localization and positional homeostasisPreprint
Yang, E., Zwart, M., Rubinov, M., James, B., Wei, Z., Narayan, S., Vladimirov, N., Mensh, B. D., Fitzgerald, J. E., & Ahrens, M. B. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.11.26.468907 · Cited by 5
“2H) 33,58–60 .”
Monocular nasotemporal optokinetic asymmetry—unraveling the mystery
Brodsky, M. C. (2019) · Journal of American Association for Pediatric Ophthalmology and Strabismus · doi:10.1016/j.jaapos.2019.07.001 · Cited by 4
Multi-species community platform for comparative neuroscience in teleost fishPreprint
Vohra, S. K., Herrera, K. J., Tavhelidse, T., Wittbrodt, J., Knoblich, S., Seleit, A., Aulehla, A., Boulanger-Weill, J., Chambule, S., Aspiras, A. C., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.02.14.580400 · Cited by 4
“This is aligned with most behavioral research in zebrafish larvae, which is usually conducted at 5-7 dpf (Oteiza et al. 2017; X. Chen and Engert 2014; Kubo et al. 2014).”
MethodReynolds, P., Marchi, D., Ling, Y. T., Slangewal, K., Capelle, M. Q., Chalakova, Z., Bahl, A., & Hindges, R. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.04.29.651180 · Cited by 4
Synchronization of behavioral and cardiac dynamics in larval zebrafish
Herrera, K. J., Zarghani-Shiraz, A., Ahrens, M. B., Engert, F., & Fishman, M. C. (2026) · Cell Reports · doi:10.1016/j.celrep.2026.116947 · Cited by 6
Binocular integration of prey stimuli in the zebrafish visual system
Tian, G., Lam, T. K. C., Yan, G., He, Y., Khan, B., Qu, J. Y., & Semmelhack, J. L. (2025) · Current Biology · doi:10.1016/j.cub.2025.05.063 · Cited by 3
Insect Neurobiology: An Eye to Forward Motion
Tomsic, D., & Theobald, J. C. (2017) · Current Biology · doi:10.1016/j.cub.2017.09.038 · Cited by 3
Motor-Driven Modulation in Visual Neural Circuits
Fujiwara, T., & Chiappe, M. E. (2017) · Springer eBooks · doi:10.1007/978-3-319-57363-2_10 · Cited by 3
Spatial Mapping in Perpetual Darkness
Santacruz, A., Garcia, O. M., Tinoco‐Cuellar, M., Rangel‐Huerta, E., & Maldonado, E. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-802148-4.00018-9 · Cited by 3
Neural circuits mediating visual stabilization during active motion in zebrafishPreprint
Sun, S., Zuo, Z., Manxiu, M., Qian, C., Chen, L., Zhou, W., Drasbek, K. R., & Liu, Z. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/566760 · Cited by 2
“…motor integration (Knogler et al., 2017; Koyama et al., 2011; Mu et al., 2012; Schoonheim et al., 2010; Wolf et al., 2017; Yao et al., 2016), OKR (Kubo et al., 2014; Portugues et al., 2014), VPNI (Goncalves et al., 2014; Miri et al., 2011), motion after effect (Perez-Schuster et al., 2016), and…”
BackgroundMethodInfluentialEarly visual experience elicits cellular and functional plasticity in the retina and alters behavior
Reynolds, P., Marchi, D., Ling, Y. T., Slangewal, K., Capelle, M. Q., Chalakova, Z., Bahl, A., & Hindges, R. (2026) · Neuron · doi:10.1016/j.neuron.2026.05.001 · Cited by 9
Sparse Coding Predicts Optic Flow Specifities of Zebrafish Pretectal Neurons
Ecke, G. A., Mikulasch, F. A., Bruijns, S. A., Witschel, T., Arrenberg, A. B., & Mallot, H. A. (2018) · Lecture notes in computer science · doi:10.1007/978-3-030-01424-7_64 · Cited by 2
Self-citationSpatial Subdomains in the Optic Tectum for the Encoding of Visual Information
Shallcross, T., Diana, G., Burrone, J., & Meyer, M. P. (2026) · Journal of Neuroscience · doi:10.1523/jneurosci.1438-24.2025 · Cited by 2
Minicerebellum, now available for reductionists’ functional study
Okamoto, H. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1411821111 · Cited by 2
Zebrafish Dscaml1 is Essential for Retinal Patterning and Function of Oculomotor SubcircuitsPreprint
Ma, M., Ramirez, A. D., Wang, T., Roberts, R. L., Harmon, K. E., Schoppik, D., Sharma, A., Kuang, C., Goei, S. L., Gagnon, J. A., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/658161 · Cited by 2
Fouke, K. E., He, Z., Loring, M. D., & Naumann, E. A. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.11.22.624938 · Cited by 2
Cardiac interoception impacts behavior and brain-wide neuronal dynamicsPreprint
Herrera, K. J., Zarghani-Shiraz, A., Ahrens, M. B., Engert, F., & Fishman, M. C. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.04.25.650721 · Cited by 2
Matsuda, K., Wang, C., Kakinuma, H., Toyoda, A., Shiraki, T., Kawakami, K., & Kubo, F. (2026) · Nature Communications · doi:10.1038/s41467-026-71371-6 · Cited by 1
Self-citationBhattacharya, B., Roy, S., Bal, B., Mukherjee, S., Bhat, A., & Ghosh, K. (2025) · Zebrafish · doi:10.1177/15458547251365847 · Cited by 1
Color modulation of motion aftereffect on optomotor response in zebrafish larvae
Ulhaq, Z. S. (2026) · Neuroscience Letters · doi:10.1016/j.neulet.2026.138538 · Cited by 1
Guilbeault, N. C., Westbrook, M. E., Krishna, V. S., Ansari, R., Keth, A., Arrenberg, A. B., Juntti, S. A., & Thiele, T. R. (2026) · iScience · doi:10.1016/j.isci.2026.117136 · Cited by 1
Self-citationNeuroimaging Phenotypes in Zebrafish
Ullmann, J. F. P., & Janke, A. L. (2017) · Springer eBooks · doi:10.1007/978-3-319-33774-6_13 · Cited by 1
Transcriptional control of visual neural circuit development by GS homeobox 1
Schmidt, A. R., Placer, H. J., Muhammad, I., Shephard, R., Patrick, R. L., Saurborn, T., Horstick, E. J., & Bergeron, S. A. (2024) · PLoS Genetics · doi:10.1371/journal.pgen.1011139 · Cited by 1
Control algorithms underlying the translational optomotor responsePreprint
Holman, J. G., Lai, W. W. K., Pichler, P., Saska, D., Lagnado, L., & Buckley, C. L. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.03.16.484575 · Cited by 1
“There is neurobiological evidence for the first (11,12,14,32,33) and last of these (16,39) but less evidence relevant to the proposed intermediate processes.”
BackgroundBinocular integration of prey stimuli in the zebrafish visual systemPreprint
Tian, G., Lam, T. K. C., Yan, G., He, Y., Khan, B., Qu, J. Y., & Semmelhack, J. L. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.09.08.611846 · Cited by 1
“So far, although binocular interactions have been identified in the visual response to whole-field motion and luminance stimuli, 20–22 bin-ocular prey-responsive neurons (bino-PRNs) have not been found in zebrafish.”
Slangewal, K., Aimon, S., Capelle, M. Q., Kämpf, F., Naumann, H., Baier, H., Slanchev, K., & Bahl, A. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.08.12.669772 · Cited by 1
“Visual motion is encoded retinotopically in direction-selective layers of the tectum 48 and pretectum 31,35,49 , and then further refined and temporally integrated in the anterior hindbrain to produce motor output 17,18 .”
Self-citationBrain-Wide Neural Dynamics Underlying Looming-Evoked Escapes and Spontaneous Exploration
Dunn, T. (2015) · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
Optogenetic Interpellation of Behavior Employing Unrestrained Zebrafish Larvae
Ryu, S., & Marco, R. J. D. (2017) · Neuromethods · doi:10.1007/978-1-4939-7417-7_7
Anatomical and functional analysis of non-retinal tectal afferents in larval zebrafish
Heap, L. A. (2017) · The University of Queensland · doi:10.14264/uql.2017.805
“In the case of optophysiology data, the analysis determines whether a stimulus feature causes a fluorescent change that is significantly higher than the baseline level of firing (Kubo et al., 2014; Naumann et al., 2016).”
BackgroundDynamic neural computation during movement
FUJIWARA, T. (2020) · Hikaku seiri seikagaku(Comparative Physiology and Biochemistry) · doi:10.3330/hikakuseiriseika.37.62
Legorreta, E. M. (2020) · The University of Queensland · doi:10.14264/uql.2020.647
1 ニラの生理障害「葉先枯れ」の原因究明(第1報) : 水耕での要素過剰処理による「葉先枯れ」の再現(関西支部講演会,2009年度各支部会)
森永, 茂., 岡林, 美., 飯田, 佳., & 大崎, 佳. (2010) · 日本土壌肥料学会講演要旨集
Motion vision: Course control in the developing visual system
Ali, M. A., & Bollmann, J. H. (2022) · Current Biology · doi:10.1016/j.cub.2022.04.084
Fu, R., Liu, H., Zhang, Y., Mao, L., Zhu, L., Jiang, H., Zhang, L. H., & Liu, X. (2023) · SSRN Electronic Journal · doi:10.2139/ssrn.4597360
Forsthofer, M., Gordy, C., Kolluri, M., & Straka, H. (2023) · eNeuro · doi:10.1523/eneuro.0371-23.2023
“Appropriately wired fi bers to contralateral temporally selective pretectal neurons in the left pretectum will then initiate a rightward OKR (Kubo et al., 2014; Wu et al., 2020).”
BackgroundSaccade subtypes: Eyes on the prize
Bellegarda, C., & Schoppik, D. (2025) · Current Biology · doi:10.1016/j.cub.2024.11.045
Klusmann, F. S., Kögler, A. C., Slangewal, K., Önder, O., Naumann, H., Marx, A., Bahl, A., & Müller, P. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.01.691575
Fornetto, C., Tiso, N., Pavone, F. S., & Vanzi, F. (2020) · Figshare · doi:10.6084/m9.figshare.13294517
Fornetto, C., Tiso, N., Pavone, F. S., & Vanzi, F. (2020) · Figshare · doi:10.6084/m9.figshare.13294520
Fornetto, C., Tiso, N., Pavone, F. S., & Vanzi, F. (2020) · Figshare · doi:10.6084/m9.figshare.13294532
Fornetto, C., Tiso, N., Pavone, F. S., & Vanzi, F. (2020) · Figshare · doi:10.6084/m9.figshare.13294529
Fornetto, C., Tiso, N., Pavone, F. S., & Vanzi, F. (2020) · Figshare · doi:10.6084/m9.figshare.13294511
Fornetto, C., Tiso, N., Pavone, F. S., & Vanzi, F. (2020) · Figshare · doi:10.6084/m9.figshare.13294538
Fornetto, C., Tiso, N., Pavone, F. S., & Vanzi, F. (2020) · Figshare · doi:10.6084/m9.figshare.13294535
Fornetto, C., Tiso, N., Pavone, F. S., & Vanzi, F. (2020) · Figshare · doi:10.6084/m9.figshare.13294526
Fornetto, C., Tiso, N., Pavone, F. S., & Vanzi, F. (2020) · Figshare · doi:10.6084/m9.figshare.13294514
Decoding Neural Circuits for Visually Guided Behavior in Zebrafish: Development of CaMPARIseq
Matsuda, K. (2025) · Hikaku seiri seikagaku(Comparative Physiology and Biochemistry) · doi:10.3330/hikakuseiriseika.42.158
Pannexin 1a regulates visual system development and ocular integrity in zebrafish
Sabour, S., Houshangi-Tabrizi, S., Zoidl, G., Zoidl, G., & Tabatabaei, N. (2026) · iScience · doi:10.1016/j.isci.2026.114925
“43,44 Electrophysiological studies have demonstrated that deficits in any component of this circuit, including reduced retinal contrast sensitivity, altered pretectal activation, or disrupted tegmental firing, can impair OKR gain and saccade timing.”
Boulanger-Weill, J. (2015) · theses.fr (ABES) · doi:10.70675/2e2345c3z54b6z40bbzbb39z21007cd16800
“Optogentic tools can also be used to map connectivity (Kubo et al., 2014), or suppress neuronal activity (Arrenberg et al., 2010).”
Neural circuits for decision-making based on pineal photoreception in zebrafish
Wada, S., Yamamoto, Y., Saito, T., Hibi, M., Koyanagi, M., & Terakita, A. (2026) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2520290123
“This indicates that the tegmentum neurons may be affected by neural responses in the arborization fields (AFs 1 to10), the direct projection area of retinal ganglion cells, including the tectum (AF10) and pretectum (AFs 1 to 9), with left and right spatial properties (17, 24, 42–44).”
Kulkarni, A. (2017) · theses.fr (ABES) · doi:10.70675/b28867a5zcc5dz4649z8912za9ace126d231
Neuronal populations underlying locomotion in zebrafish
Sternberg, J. R. (2016) · theses.fr (ABES) · doi:10.70675/4672b940zaeefz4dc4zadc5z91d95b993c6f
Cohen, L., Cohen-Duwek, H., & Tsur, E. E. (2026) · iScience · doi:10.1016/j.isci.2026.115824
“However, there are several possible mechanisms for depth perception in fish, 22 among them using visual parallax, i.e., how objects shift on the retina as they move, 23 and optical flow 24 that may be used to estimate distances from walls or boundaries.”
Origin of Schooling and Collective Environmental Adaptation in ZebrafishPreprint
Chen, M., Wang, P., & Li, B. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.07.01.732092
Huang, Y., Wu, J., Yang, J., Zhang, Z., & Lan, Y. (2026) · Aquatic Toxicology · doi:10.1016/j.aquatox.2026.107992
Zhao, Z., Szydlo-Shein, A., Darnet, L., Trevers, K. E., & Hindges, R. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.08.28.747855
“41,66,70 In these regions, as well as in regions involved in interhemispheric communication, Tenm4 exhibits moderate expression, suggesting involvement in the construction of visual circuits and visual behavioral phenotypes, which is consistent with our observed OKR and OMR phenotypes in tenm4…”
A dopaminergic visuomotor gateway to the zebrafish optic tectumPreprint
Brehm, N., Chakraborty, S., & Bollmann, J. H. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.09.15.751684
Wagner, F., Kopecki, I., Elings, J., Enders, U., Lindig, A., Maltzahn, K., Roessger, T., Roth, M. S., Royan, M., Stamm, J., et al. (2026) · PLoS ONE · doi:10.1371/journal.pone.0348737
“In daylight, fish can track their movement using visual markers [51,87,88], but this sense is likely to be severely restricted in darkness.”
Metadata
- Authors
- Kubo, F., Hablitzel, B., Dal Maschio, M., Driever, W., Baier, H., & Arrenberg, A. B.
- Affiliations
- Max Planck Institute of Neurobiology (DE)
- University of Freiburg (DE)
- Max Planck Society (DE)
- Corresponding author
- Baier, Herwig
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2014-03
- Volume
- 81
- Issue
- 6
- Pages
- 1344-1359
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W2067473018
- Cited by
- 182
- References
- 60
- Citations by year
- 2026: 16 · 2025: 14 · 2024: 8 · 2023: 12 · 2022: 14 · 2021: 12 · 2020: 21 · 2019: 16 · 2018: 12 · 2017: 19 · 2016: 14 · 2015: 13 · 2014: 10
- FWCI
- 10.39
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- Max Planck Digital Library (submittedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- Padua Research Archive (University of Padova) (submittedVersion)
- Funders
- Deutsche Forschungsgemeinschaft (EXC‐294‐BIOSS, SFB780, (EXC 294))
- Max-Planck-Gesellschaft
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurobiology and Insect Physiology Research
- Keywords
- optical flow, horizontal eye movements, optokinetic response, optomotor response, zebrafish, direction selectivity, binocular vision, neural circuit organization, optogenetic manipulation, in vivo calcium imaging
- MeSH terms
- Animals, Eye Movements, Motion Perception, Neurons, Photic Stimulation, Visual Fields, Visual Pathways, Zebrafish, Nystagmus, Optokinetic, Optic Flow
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
