Pre- and postsynaptic twists in BDNF secretion and action in synaptic plasticity.

A synaptic model of memory: long-term potentiation in the hippocampus

Bliss, T. V. P., & Collingridge, G. L. (1993) · Nature · doi:10.1038/361031a0 · Cited by 11,566

LTP and LTD

Malenka, R. C., & Bear, M. F. (2004) · Neuron · doi:10.1016/j.neuron.2004.09.012 · Cited by 3,968

The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function

Egan, M. F., Kojima, M., Callicott, J. H., Goldberg, T. E., Kolachana, B. S., Bertolino, A., Zaitsev, E., Gold, B., Goldman, D., Dean, M., et al. (2003) · Cell · doi:10.1016/s0092-8674(03)00035-7 · Cited by 3,888

Neurotrophin regulation of neural circuit development and function

Park, H., & Poo, M.-M. (2013) · Nature Reviews Neuroscience · doi:10.1038/nrn3379 · Cited by 2,060

Spike Timing–Dependent Plasticity: A Hebbian Learning Rule

Caporale, N., & Dan, Y. (2008) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.31.060407.125639 · Cited by 1,997

BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain

Coull, J. A. M., Beggs, S., Boudreau, D., Boivin, D., Tsuda, M., Inoue, K., Gravel, C., Salter, M. W., & De Koninck, Y. (2005) · Nature · doi:10.1038/nature04223 · Cited by 1,965

Synaptic tagging and long-term potentiation

Frey, U., & Morris, R. G. M. (1997) · Nature · doi:10.1038/385533a0 · Cited by 1,736

Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition

Vaynman, S., Ying, Z., & Gomez‐Pinilla, F. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03720.x · Cited by 1,460

Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus

Smith, M., Makino, S., Květňanský, R., & Post, R. M. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-03-01768.1995 · Cited by 1,449

Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor.

Korte, M., Carroll, P., Wolf, E., Brem, G., Thoenen, H., & Bonhoeffer, T. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.19.8856 · Cited by 1,426

The Microbiota-Gut-Brain Axis

Cryan, J. F., O'Riordan, K. J., Cowan, C. S. M., Sandhu, K. V., Bastiaanssen, T. F. S., Boehme, M., Codagnone, M. G., Cussotto, S., Fulling, C., Golubeva, A. V., et al. (2019) · Physiological Reviews · doi:10.1152/physrev.00018.2018 · Cited by 5,286

BDNF: A Key Factor with Multipotent Impact on Brain Signaling and Synaptic Plasticity

Kowiański, P., Lietzau, G., Czuba, E., Waśkow, M., Steliga, A., & Moryś, J. (2018) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-017-0510-4 · Cited by 1,359

Neurotrophic Factor BDNF, Physiological Functions and Therapeutic Potential in Depression, Neurodegeneration and Brain Cancer

Colucci-D’Amato, L., Speranza, L., & Volpicelli, F. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21207777 · Cited by 991

Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on Neuroinflammation

Lima Giacobbo, B., Doorduin, J., Klein, H. C., Dierckx, R. A. J. O., Bromberg, E., & de Vries, E. F. J. (2019) · Molecular Neurobiology · doi:10.1007/s12035-018-1283-6 · Cited by 750

BDNF and Hippocampal Synaptic Plasticity

Leal, G., Bramham, C. R., & Duarte, C. B. (2017) · Vitamins and Hormones · doi:10.1016/bs.vh.2016.10.004 · Cited by 425

Regulation of hippocampal synaptic plasticity by BDNF

Leal, G., Afonso, P. M., Salazar, I. L., & Duarte, C. B. (2015) · Brain Research · doi:10.1016/j.brainres.2014.10.019 · Cited by 410

Neurobiology of local and intercellular BDNF signaling

Sasi, M., Vignoli, B., Canossa, M., & Blum, R. (2017) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-017-1964-4 · Cited by 324

Role of BDNF in the Pathophysiology and Treatment of Depression: Activity-Dependent Effects Distinguish Rapid-Acting Antidepressants

Duman, R. S., Deyama, S., & Fogaça, M. V. (2021) · European Journal of Neuroscience · doi:10.1111/ejn.14630 · Cited by 321

Dance training is superior to repetitive physical exercise in inducing brain plasticity in the elderly

Rehfeld, K., Lüders, A., Hökelmann, A., Leßmann, V., Kaufmann, J., Brigadski, T., Müller, P., & Müller, N. G. (2018) · PLoS ONE · doi:10.1371/journal.pone.0196636 · Cited by 300

Neuromodulation of Spike-Timing-Dependent Plasticity: Past, Present, and Future

Brzosko, Z., Mierau, S. B., & Paulsen, O. (2019) · Neuron · doi:10.1016/j.neuron.2019.05.041 · Cited by 267

Lactate and BDNF: Key Mediators of Exercise Induced Neuroplasticity?

Müller, P., Duderstadt, Y., Lessmann, V., & Müller, N. G. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9041136 · Cited by 241

Modulation of Intestinal Microbiota by the Probiotic VSL#3 Resets Brain Gene Expression and Ameliorates the Age-Related Deficit in LTP

Distrutti, E., O’Reilly, J.-A., McDonald, C., Cipriani, S., Renga, B., Lynch, M. A., & Fiorucci, S. (2014) · PLoS ONE · doi:10.1371/journal.pone.0106503 · Cited by 237

JAK-STAT signaling in inflammation and stress-related diseases: implications for therapeutic interventions

Sarapultsev, A., Gusev, E., Komelkova, M. V., Utepova, I. A., Luo, S., & Hu, D. (2023) · Molecular Biomedicine · doi:10.1186/s43556-023-00151-1 · Cited by 254

Evolution of Neuroplasticity in Response to Physical Activity in Old Age: The Case for Dancing

Müller, P., Rehfeld, K., Schmicker, M., Hökelmann, A., Dordevic, M., Leßmann, V., Brigadski, T., Kaufmann, J., & Müller, N. G. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00056 · Cited by 249

The physiology of regulated BDNF release

Brigadski, T., & Leßmann, V. (2020) · Cell and Tissue Research · doi:10.1007/s00441-020-03253-2 · Cited by 218

The Aerobic and Cognitive Exercise Study (ACES) for Community-Dwelling Older Adults With or At-Risk for Mild Cognitive Impairment (MCI): Neuropsychological, Neurobiological and Neuroimaging Outcomes of a Randomized Clinical Trial

Anderson‐Hanley, C., Barcelos, N. M., Zimmerman, E. A., Gillen, R. W., Dunnam, M., Cohen, B. D., Yerokhin, V., Miller, K. E., Hayes, D. J., Arciero, P. J., et al. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00076 · Cited by 194

New insight in expression, transport, and secretion of brain-derived neurotrophic factor: Implications in brain-related diseases

Adachi, N. (2014) · World Journal of Biological Chemistry · doi:10.4331/wjbc.v5.i4.409 · Cited by 171

Aerobic Exercise as a Tool to Improve Hippocampal Plasticity and Function in Humans: Practical Implications for Mental Health Treatment

Kandola, A., Hendrikse, J., Lucassen, P. J., & Yücel, M. (2016) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2016.00373 · Cited by 155

Cellular and molecular mechanisms regulating neuronal growth by brain‐derived neurotrophic factor

González‐Gutiérrez, A., Moya‐Alvarado, G., González-Billault, C. E., & Bronfman, F. C. (2016) · Cytoskeleton · doi:10.1002/cm.21312 · Cited by 164

Can fear extinction be enhanced? A review of pharmacological and behavioral findings

Fitzgerald, P. J., Seemann, J. R., & Maren, S. (2013) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2013.12.007 · Cited by 167

Direct current stimulation boosts hebbian plasticity in vitro

Kronberg, G., Rahman, A., Sharma, M., Bikson, M., & Parra, L. C. (2019) · Brain stimulation · doi:10.1016/j.brs.2019.10.014 · Cited by 159

Two-Stage Translational Control of Dentate Gyrus LTP Consolidation Is Mediated by Sustained BDNF-TrkB Signaling to MNK

Panja, D., Kenney, J. W., D’Andrea, L., Zalfa, F., Vedeler, A., Wibrand, K., Fukunaga, R., Bagni, C., Proud, C. G., & Bramham, C. R. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.10.016 · Cited by 143

Brain-derived neurotrophic factor

Benarroch, E. E. (2015) · Neurology · doi:10.1212/wnl.0000000000001507 · Cited by 138

Theta Burst Firing Recruits BDNF Release and Signaling in Postsynaptic CA1 Neurons in Spike-Timing-Dependent LTP

Edelmann, E., Cepeda-Prado, E., Franck, M., Lichtenecker, P., Brigadski, T., & Leßmann, V. (2015) · Neuron · doi:10.1016/j.neuron.2015.04.007 · Cited by 132

Extracellular proteolysis in structural and functional plasticity of mossy fiber synapses in hippocampus

Wiera, G., & Mozrzymas, J. W. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00427 · Cited by 121

Pleiotropic effects of BDNF on the cerebellum and hippocampus: Implications for neurodevelopmental disorders

Camuso, S., Rosa, P. L., Fiorenza, M. T., & Canterini, S. (2021) · Neurobiology of Disease · doi:10.1016/j.nbd.2021.105606 · Cited by 126

Dopaminergic innervation and modulation of hippocampal networks

Edelmann, E., & Leßmann, V. (2018) · Cell and Tissue Research · doi:10.1007/s00441-018-2800-7 · Cited by 117

Peri-Synaptic Glia Recycles Brain-Derived Neurotrophic Factor for LTP Stabilization and Memory Retention

Vignoli, B., Battistini, G., Melani, R., Blum, R., Santi, S., Berardi, N., & Canossa, M. (2016) · Neuron · doi:10.1016/j.neuron.2016.09.031 · Cited by 113

The Role of BDNF as a Biomarker in Cognitive and Sensory Neurodegeneration

Pisani, A., Paciello, F., VECCHIO, V. D., Malesci, R., Corso, E. D., Cantone, E., & Fetoni, A. R. (2023) · Journal of Personalized Medicine · doi:10.3390/jpm13040652 · Cited by 127

Moderate treadmill exercise ameliorates amyloid-β-induced learning and memory impairment, possibly via increasing AMPK activity and up-regulation of the PGC-1α/FNDC5/BDNF pathway

Azimi, M., Gharakhanlou, R., Naghdi, N., Khodadadi, D., & Heysieattalab, S. (2018) · Peptides · doi:10.1016/j.peptides.2017.12.027 · Cited by 112

All for One But Not One for All: Excitatory Synaptic Scaling and Intrinsic Excitability Are Coregulated by CaMKIV, Whereas Inhibitory Synaptic Scaling Is Under Independent Control

Joseph, A., & Turrigiano, G. G. (2017) · The Journal of Neuroscience · doi:10.1523/jneurosci.0618-17.2017 · Cited by 94

LTP at Hilar Mossy Cell-Dentate Granule Cell Synapses Modulates Dentate Gyrus Output by Increasing Excitation/Inhibition Balance

Hashimotodani, Y., Nasrallah, K., Jensen, K. R., Chávez, A. E., Carrera, D., & Castillo, P. E. (2017) · Neuron · doi:10.1016/j.neuron.2017.07.028 · Cited by 104

BDNF impact on synaptic dynamics: extra or intracellular long-term release differently regulates cultured hippocampal synapses

Rauti, R., Cellot, G., D’Andrea, P., Colliva, A., Scaini, D., Tongiorgi, E., & Ballerini, L. (2020) · Molecular Brain · doi:10.1186/s13041-020-00582-9 · Cited by 78

Synaptotagmin-11 mediates a vesicle trafficking pathway that is essential for development and synaptic plasticityPreprint

Shimojo, M., Madara, J., Pankow, S., Liu, X., Yates, J., Südhof, T. C., & Maximov, A. (2019) · Genes & Development · doi:10.1101/gad.320077.118 · Cited by 80

Mechanisms Controlling the Expression and Secretion of BDNF

Arévalo, J. C., & Deogracias, R. (2023) · Biomolecules · doi:10.3390/biom13050789 · Cited by 89

Sleep and protein synthesis-dependent synaptic plasticity: impacts of sleep loss and stress

Grønli, J., Soule, J. D., & Bramham, C. R. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2013.00224 · Cited by 79

Neurotrophin Signaling and Stem Cells—Implications for Neurodegenerative Diseases and Stem Cell Therapy

Pramanik, S., Sulistio, Y. A., & Heese, K. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-0214-7 · Cited by 77

The Role of Neurotrophin Signaling in Age-Related Cognitive Decline and Cognitive Diseases

Numakawa, T., & Odaka, H. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23147726 · Cited by 101

Aerobic exercise and a BDNF-mimetic therapy rescue learning and memory in a mouse model of Down syndrome

Parrini, M., Ghezzi, D., Deidda, G., Medrihan, L., Castroflorio, E., Alberti, M., Baldelli, P., Cancedda, L., & Contestabile, A. (2017) · Scientific Reports · doi:10.1038/s41598-017-17201-8 · Cited by 77

Methylome-wide association findings for major depressive disorder overlap in blood and brain and replicate in independent brain samples

Aberg, K. A., Dean, B., Shabalin, A. A., Chan, R. F., Han, L. K. M., Zhao, M., van Grootheest, G., Xie, L. Y., Milaneschi, Y., Clark, S. L., et al. (2020) · Molecular Psychiatry · doi:10.1038/s41380-018-0247-6 · Cited by 73

The RNA-Binding Protein hnRNP K Mediates the Effect of BDNF on Dendritic mRNA Metabolism and Regulates Synaptic NMDA Receptors in Hippocampal Neurons

Leal, G., Comprido, D., Luca, P. D., de Morais, E. C. C., Rodrigues, L., Mele, M., Santos, A. R., Costa, R. O., Pinto, M. J., Patil, S. S., et al. (2017) · eNeuro · doi:10.1523/eneuro.0268-17.2017 · Cited by 71

Elevated Plasma microRNA-206 Levels Predict Cognitive Decline and Progression to Dementia from Mild Cognitive Impairment

Kenny, A., McArdle, H., Calero, M., Rábano, A., Madden, S. F., Adamson, K., Forster, R. J., Spain, E., Prehn, J. H. M., Henshall, D. C., et al. (2019) · Biomolecules · doi:10.3390/biom9110734 · Cited by 77

Stress-Related Dysfunction of Adult Hippocampal Neurogenesis—An Attempt for Understanding Resilience?

Leschik, J., Lutz, B., & Gentile, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22147339 · Cited by 77

Targeting BDNF signaling by natural products: Novel synaptic repair therapeutics for neurodegeneration and behavior disorders

Bawari, S., Tewari, D., Argüelles, S., Sah, A. N., Nabavi, S. F., Xu, S., Vacca, R. A., Nabavi, S. M., & Shirooie, S. (2019) · Pharmacological Research · doi:10.1016/j.phrs.2019.104458 · Cited by 69

Toward a unified biological hypothesis for the BDNF Val66Met-associated memory deficits in humans: a model of impaired dendritic mRNA trafficking

Baj, G., Carlino, D., Gardossi, L., & Tongiorgi, E. (2013) · Frontiers in Neuroscience · doi:10.3389/fnins.2013.00188 · Cited by 69

BDNF contributes to the development of neuropathic pain by induction of spinal long-term potentiation via SHP2 associated GluN2B-containing NMDA receptors activation in rats with spinal nerve ligation

Ding, X., Cai, J., Li, S., Liu, X., Wan, Y., & Xing, G. (2014) · Neurobiology of Disease · doi:10.1016/j.nbd.2014.10.025 · Cited by 67

Increased Hippocampal ProBDNF Contributes to Memory Impairments in Aged Mice

Buhusi, M. C., Etheredge, C., Granholm, A., & Buhusi, C. V. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00284 · Cited by 67

Ketamine-induced changes in plasma brain-derived neurotrophic factor (BDNF) levels are associated with the resting-state functional connectivity of the prefrontal cortex

Woelfer, M., Li, M., Colic, L., Liebe, T., Di, X., Biswal, B., Murrough, J., Lessmann, V., Brigadski, T., & Walter, M. (2020) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2019.1679391 · Cited by 64

Sleep and memory: The impact of sleep deprivation on transcription, translational control, and protein synthesis in the brain

Lyons, L. C., Vanrobaeys, Y. S., & Abel, T. G. (2023) · Journal of Neurochemistry · doi:10.1111/jnc.15787 · Cited by 69

Brain-derived neurotrophic factor expression in serotonergic neurons improves stress resilience and promotes adult hippocampal neurogenesis.

Leschik, J., Gentile, A., Cicek, C., Péron, S., Tevosian, M., Beer, A., Radyushkin, K., Bludau, A., Ebner, K., Neumann, I., et al. (2022) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2022.102333 · Cited by 58

Modulation of Spike-Timing Dependent Plasticity: Towards the Inclusion of a Third Factor in Computational Models

Foncelle, A., Mendes, A., Jędrzejewska‐Szmek, J., Valtcheva, S., Berry, H., Blackwell, K. T., & Venance, L. (2018) · Frontiers in Computational Neuroscience · doi:10.3389/fncom.2018.00049 · Cited by 67

PAR2-Mediated Upregulation of BDNF Contributes to Central Sensitization in Bone Cancer Pain

Bao, Y., Hou, W., Liu, R., Gao, Y., Kong, X., Yang, L., Shi, Z., Li, W., Zheng, H., Jiang, S., et al. (2014) · Molecular Pain · doi:10.1186/1744-8069-10-28 · Cited by 57

Oxidative stress in drug-naïve first episode patients with schizophrenia and major depression: effects of disease acuity and potential confounders

Jordan, W., Dobrowolny, H., Bahn, S., Bernstein, H., Brigadski, T., Frodl, T., Isermann, B., Leßmann, V., Pilz, J., Rodenbeck, A., et al. (2016) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-016-0749-7 · Cited by 59

Brain-Derived Neurotrophic Factor: A Novel Dynamically Regulated Therapeutic Modulator in Neurological Disorders

Sharma, V., Singh, T. G., Kaur, A., Mannan, A., & Dhiman, S. (2022) · Neurochemical Research · doi:10.1007/s11064-022-03755-1 · Cited by 58

The tumor-nerve circuit in breast cancer

Cui, Q., Jiang, D., Zhang, Y., & Chen, C. (2023) · Cancer and Metastasis Reviews · doi:10.1007/s10555-023-10095-1 · Cited by 55

Acetylcholine-modulated plasticity in reward-driven navigation: a computational study

Zannone, S., Brzosko, Z., Paulsen, O., & Clopath, C. (2018) · Scientific Reports · doi:10.1038/s41598-018-27393-2 · Cited by 51

Pea3 Transcription Factors, Etv4 and Etv5, Are Required for Proper Hippocampal Dendrite Development and Plasticity

Fontanet, P., Ríos, A. S., Alsina, F. C., Paratcha, G., & Ledda, F. (2016) · Cerebral Cortex · doi:10.1093/cercor/bhw372 · Cited by 51

Coexistence of Multiple Types of Synaptic Plasticity in Individual Hippocampal CA1 Pyramidal Neurons

Edelmann, E., Cepeda-Prado, E., & Leßmann, V. (2017) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2017.00007 · Cited by 48

Brothers in Arms: ProBDNF/BDNF and sAPPα/Aβ-Signaling and Their Common Interplay with ADAM10, TrkB, p75NTR, Sortilin, and sorLA in the Progression of Alzheimer’s Disease

Eggert, S., Kins, S., Endres, K., & Brigadski, T. (2022) · Biological Chemistry · doi:10.1515/hsz-2021-0330 · Cited by 46

Use it and boost it with physical and mental activity.

Korol, D. L., Gold, P. E., & Scavuzzo, C. J. (2013) · Hippocampus · doi:10.1002/hipo.22197 · Cited by 45

BDNF regulation of synaptic structure, function, and plasticity

Bramham, C. R., & Panja, D. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.08.012 · Cited by 45

A Jacob/Nsmf Gene Knockout Results in Hippocampal Dysplasia and Impaired BDNF Signaling in Dendritogenesis

Spilker, C., Nullmeier, S., Grochowska, K. M., Schumacher, A., Butnaru, I., Macharadze, T., Gomes, G. M., Yuanxiang, P., Bayraktar, G., Rodenstein, C., et al. (2016) · PLoS Genetics · doi:10.1371/journal.pgen.1005907 · Cited by 43

Abnormal TDP‐43 function impairs activity‐dependent BDNF secretion, synaptic plasticity, and cognitive behavior through altered Sortilin splicing

Tann, J. Y., Wong, L., Sajikumar, S., & Ibáñez, C. F. (2019) · The EMBO Journal · doi:10.15252/embj.2018100989 · Cited by 42

Brain‐derived neurotrophic factor ‐induced regulation of RNA metabolism in neuronal development and synaptic plasticity

Costa, R. O., Martins, L. F., Tahiri, E., & Duarte, C. B. (2022) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1713 · Cited by 45

Rapid regulation of sialidase activity in response to neural activity and sialic acid removal during memory processing in rat hippocampus

Minami, A., Meguro, Y., Ishibashi, S., Ishii, A., Shiratori, M., Sai, S., Horii, Y., Shimizu, H., Fukumoto, H., Shimba, S., et al. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.764357 · Cited by 42

Synaptic membrane rafts: traffic lights for local neurotrophin signaling?

Zonta, B., & Minichiello, L. (2013) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2013.00009 · Cited by 41

Caffeine‐mediated BDNF release regulates long‐term synaptic plasticity through activation of IRS2 signaling

Lao‐Peregrín, C., Ballesteros, J. J., Fernández, M., Zamora‐Moratalla, A., Saavedra, A., Gómez-Lázaro, M., Pérez‐Navarro, E., Burks, D. J., & Martín, E. D. (2016) · Addiction Biology · doi:10.1111/adb.12433 · Cited by 41

The ins and outs of inhibitory synaptic plasticity: Neuron types, molecular mechanisms and functional roles

Capogna, M., Castillo, P. E., & Maffei, A. (2020) · European Journal of Neuroscience · doi:10.1111/ejn.14907 · Cited by 45

Increased production of BDNF in colonic epithelial cells induced by fecal supernatants from diarrheic IBS patients

Wang, P., Chen, F.-X., Du, C., Li, C., Yu, Y., Zuo, X., & Li, Y. (2015) · Scientific Reports · doi:10.1038/srep10121 · Cited by 41

Mahuang-Fuzi-XixinDecoction Reverses Depression-Like Behavior in LPS-Induced Mice by Regulating NLRP3 Inflammasome and Neurogenesis

Jing, W., Song, S., Sun, H., Chen, Y., Zhao, Q., Zhang, Y., Dai, G., & Ju, W. (2019) · Neural Plasticity · doi:10.1155/2019/1571392 · Cited by 40

Comparison of the effects of open vs. closed skill exercise on the acute and chronic BDNF, IGF-1 and IL-6 response in older healthy adults

Behrendt, T., Kirschnick, F., Kröger, L., Beileke, P., Rezepin, M., Brigadski, T., Leßmann, V., & Schega, L. (2021) · BMC Neuroscience · doi:10.1186/s12868-021-00675-8 · Cited by 48

Requirement of an Early Activation of BDNF/c-Fos Cascade in the Retrosplenial Cortex for the Persistence of a Long-Lasting Aversive Memory

Katche, C., & Medina, J. H. (2015) · Cerebral Cortex · doi:10.1093/cercor/bhv284 · Cited by 38

BDNF: a regulator of learning and memory processes with clinical potential

Brigadski, T., & Leßmann, V. (2014) · e-Neuroforum · doi:10.1007/s13295-014-0053-9 · Cited by 42

Signaling pathways controlling activity-dependent local translation of BDNF and their localization in dendritic arbors

Baj, G., Pinhero, V., Vaghi, V., & Tongiorgi, E. (2016) · Journal of Cell Science · doi:10.1242/jcs.177626 · Cited by 37

BDNF-endocannabinoid interactions at neocortical inhibitory synapses require phospholipase C signaling

Zhao, L., & Levine, E. S. (2013) · Journal of Neurophysiology · doi:10.1152/jn.00554.2013 · Cited by 36

Lipid Rafts: The Maestros of Normal Brain Development

Viljetić, B., Blažetić, S., Labak, I., Ivić, V., Zjalić, M., Heffer, M., & Balog, M. (2024) · Biomolecules · doi:10.3390/biom14030362 · Cited by 36

Impact of an additional chronic BDNF reduction on learning performance in an Alzheimer mouse model

Psotta, L., Rockahr, C., Gruß, M., Kirches, E., Braun, K., Leßmann, V., Bock, J., & Endres, T. (2015) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2015.00058 · Cited by 35

Activin Signaling in the Pathogenesis and Therapy of Neuropsychiatric Diseases

Link, A. S., Zheng, F., & Alzheimer, C. (2016) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2016.00032 · Cited by 38

Neurotrophin signalling in amygdala-dependent cued fear learning

Meis, S., Endres, T., & Leßmann, V. (2020) · Cell and Tissue Research · doi:10.1007/s00441-020-03260-3 · Cited by 40

Stepping Out of the Shade: Control of Neuronal Activity by the Scaffold Protein Kidins220/ARMS

Scholz‐Starke, J., & Cesca, F. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00068 · Cited by 35

Hydroxysafflor yellow A increases BDNF and NMDARs in the hippocampus in a vascular dementia rat model

Xing, M., Sun, Q., Wang, Y., Cheng, Y., & Zhang, N. (2016) · Brain Research · doi:10.1016/j.brainres.2016.04.030 · Cited by 34

Remote limb ischemic conditioning enhances motor learning in healthy humans

Cherry‐Allen, K. M., Gidday, J. M., Lee, J., Hershey, T. G., & Lang, C. E. (2015) · Journal of Neurophysiology · doi:10.1152/jn.01028.2014 · Cited by 34

Altered Cytokine and BDNF Levels in Individuals with Autism Spectrum Disorders

Han, Y. M. Y., Yau, S., Chan, M. M. Y., Wong, C. K., & Chan, A. S.-Y. (2022) · Brain Sciences · doi:10.3390/brainsci12040460 · Cited by 35

Non-invasive Brain Delivery and Efficacy of BDNF in APP/PS1 Transgenic Mice

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TrkB signaling regulates the cold-shock protein RBM3-mediated neuroprotection

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HIV-1 Tat protein promotes neuronal dysregulation by inhibiting E2F transcription factor 3 (E2F3)

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Amyloid-Beta Induced Changes in Vesicular Transport of BDNF in Hippocampal Neurons

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Adenosine A2A Receptors as novel upstream regulators of BDNF-mediated attenuation of hippocampal Long-Term Depression (LTD)

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Both secreted and the cellular levels of BDNF attenuated due to tau hyperphosphorylation in primary cultures of cortical neurons

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Arc 3′ UTR Splicing Leads to Dual and Antagonistic Effects in Fine-Tuning Arc Expression Upon BDNF Signaling

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Individual differences and knockout in zebrafish reveal similar cognitive effects of BDNF between teleosts and mammals

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Regulation of neuronal excitability by release of proteins from glial cells

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BDNF-induced nitric oxide signals in cultured rat hippocampal neurons: time course, mechanism of generation, and effect on neurotrophin secretion

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Prominent Postsynaptic and Dendritic Exocytosis of Endogenous BDNF Vesicles in BDNF-GFP Knock-in Mice

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Activity‐dependent dendritic secretion of brain‐derived neurotrophic factor modulates synaptic plasticity

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BDNF induces its own release to mediate presynaptic plasticityPreprint

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Role of Brain-Derived Neurotrophic Factor as a Modulator of Synaptic Plasticity

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