The DOI matches its Crossref record; 245 of the 246 references it cites were found in a registry or an index.
Pre- and postsynaptic twists in BDNF secretion and action in synaptic plasticity.
Abstract
Overwhelming evidence collected since the early 1990's strongly supports the notion that BDNF is among the key regulators of synaptic plasticity in many areas of the mammalian central nervous system. Still, due to the extremely low expression levels of endogenous BDNF in most brain areas, surprisingly little data i) pinpointing pre- and postsynaptic release sites, ii) unraveling the time course of release, and iii) elucidating the physiological levels of synaptic activity driving this secretion are available. Likewise, our knowledge regarding pre- and postsynaptic effects of endogenous BDNF at the single cell level in mediating long-term potentiation still is sparse. Thus, our review will discuss the data currently available regarding synaptic BDNF secretion in response to physiologically relevant levels of activity, and will discuss how endogenously secreted BDNF affects synaptic plasticity, giving a special focus on spike timing-dependent types of LTP and on mossy fiber LTP. We will attempt to open up perspectives how the remaining challenging questions regarding synaptic BDNF release and action might be addressed by future experiments. This article is part of the Special Issue entitled 'BDNF Regulation of Synaptic Structure, Function, and Plasticity'.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Especially in the hippocampus, this neurotrophin is thought to act on both the pre- and post-synaptic compartments, modulating synaptic efficacy, either by changing the pre-synaptic transmitter release, or by increasing post-synaptic transmitter sensitivity [15,16] to induce a long-lasting increase in synaptic plasticity.”
From Neurotrophic Factor BDNF, Physiological Functions and Therapeutic Potential in Depression, Neurodegeneration and Brain Cancer (2020) · cites this paper as [16]
In the citing paper
“The effects of BDNF on LTP are mediated by the TrkB receptor.”
From Neurotrophic Factor BDNF, Physiological Functions and Therapeutic Potential in Depression, Neurodegeneration and Brain Cancer (2020) · cites this paper as [16]
In the citing paper
“In addition, studies also show that BDNF is an important regulator of synaptic transmission and long-term potentiation (LTP) in the hippocampus and in other brain regions.”
From Neurotrophic Factor BDNF, Physiological Functions and Therapeutic Potential in Depression, Neurodegeneration and Brain Cancer (2020) · cites this paper as [16]
In the citing paper
“In particular, in the hippocampus the neurotrophin is thought to act at pre- and post-synaptic levels, modulating synaptic efficacy either by changes in pre-synaptic transmitter release, or by increased post-synaptic transmitter sensitivity (see e.g., [15,16]) to induce a long-lasting increase in synaptic plasticity.”
From Neurotrophic Factor BDNF, Physiological Functions and Therapeutic Potential in Depression, Neurodegeneration and Brain Cancer (2020) · cites this paper as [16]
In the citing paper
“The protein is thought to interact with energy metabolism to facilitate both pre- and post-synaptic mechanisms and the induction of LTP (Gomez-Pinilla and Hillman, 2013; Edelmann et al., 2014), as well as promoting the proliferation and survival of adult-born granule cells (Korol et al., 2013; Park and Poo, 2013).”
From Aerobic Exercise as a Tool to Improve Hippocampal Plasticity and Function in Humans: Practical Implications for Mental Health Treatment (2016) · cites this paper as Edelmann et al., 2014
In the citing paper
“In the brain, BDNF is involved in plasticity, neuronal survival, formation of new synapses, dendritic branching, and modulation of excitatory and inhibitory neurotransmitter profiles [11, 12].”
From Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on Neuroinflammation (2019) · cites this paper as [11]
Citations
Cites
A synaptic model of memory: long-term potentiation in the hippocampus
Bliss, T. V. P., & Collingridge, G. L. (1993) · Nature · doi:10.1038/361031a0 · Cited by 11,566
Malenka, R. C., & Bear, M. F. (2004) · Neuron · doi:10.1016/j.neuron.2004.09.012 · Cited by 3,968
Egan, M. F., Kojima, M., Callicott, J. H., Goldberg, T. E., Kolachana, B. S., Bertolino, A., Zaitsev, E., Gold, B., Goldman, D., Dean, M., et al. (2003) · Cell · doi:10.1016/s0092-8674(03)00035-7 · Cited by 3,888
Neurotrophin regulation of neural circuit development and function
Park, H., & Poo, M.-M. (2013) · Nature Reviews Neuroscience · doi:10.1038/nrn3379 · Cited by 2,060
Spike Timing–Dependent Plasticity: A Hebbian Learning Rule
Caporale, N., & Dan, Y. (2008) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.31.060407.125639 · Cited by 1,997
BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain
Coull, J. A. M., Beggs, S., Boudreau, D., Boivin, D., Tsuda, M., Inoue, K., Gravel, C., Salter, M. W., & De Koninck, Y. (2005) · Nature · doi:10.1038/nature04223 · Cited by 1,965
Synaptic tagging and long-term potentiation
Frey, U., & Morris, R. G. M. (1997) · Nature · doi:10.1038/385533a0 · Cited by 1,736
Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition
Vaynman, S., Ying, Z., & Gomez‐Pinilla, F. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03720.x · Cited by 1,460
Smith, M., Makino, S., Květňanský, R., & Post, R. M. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-03-01768.1995 · Cited by 1,449
Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor.
Korte, M., Carroll, P., Wolf, E., Brem, G., Thoenen, H., & Bonhoeffer, T. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.19.8856 · Cited by 1,426
Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior
Chen, Z.-Y., Jing, D., Bath, K. G., Ieraci, A., Khan, T., Siao, C.-J., Herrera, D. G., Toth, M., Yang, C., McEwen, B. S., et al. (2006) · Science · doi:10.1126/science.1129663 · Cited by 1,340
Patterson, S. L., Abel, T., Deuel, T. A. S., Martin, K. C., Rose, J. C., & Kandel, E. R. (1996) · Neuron · doi:10.1016/s0896-6273(00)80140-3 · Cited by 1,233
BDNF function in adult synaptic plasticity: The synaptic consolidation hypothesis
Bramham, C. R., & Messaoudi, E. (2005) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2005.06.003 · Cited by 1,193
Metaplasticity: tuning synapses and networks for plasticity
Abraham, W. C. (2008) · Nature reviews. Neuroscience · doi:10.1038/nrn2356 · Cited by 1,166
Cleavage of proBDNF by tPA/Plasmin Is Essential for Long-Term Hippocampal Plasticity
Pang, P. T., Teng, H. K., Zaitsev, E., Woo, N. T., Sakata, K., Zhen, S., Teng, K. K., Yung, W.-H., Hempstead, B. L., & Lu, B. (2004) · Science · doi:10.1126/science.1100135 · Cited by 1,136
Figurov, A., Pozzo-Miller, L. D., Olafsson, P., Wang, T., & Lu, B. (1996) · Nature · doi:10.1038/381706a0 · Cited by 1,106
Conner, J. M., Lauterborn, J. C., Yan, Q., Gall, C. M., & Varon, S. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-07-02295.1997 · Cited by 1,097
Definition of the readily releasable pool of vesicles at hippocampal synapses.
Rosenmund, C., & Stevens, C. (1996) · Neuron · doi:10.1016/s0896-6273(00)80146-4 · Cited by 1,084
The Spike-Timing Dependence of Plasticity
Feldman, D. E. (2012) · Neuron · doi:10.1016/j.neuron.2012.08.001 · Cited by 1,071
Regional distribution of brain‐derived neurotrophic factor mRNA in the adult mouse brain.
Hofer, M., Pagliusi, S. R., Hohn, A., Leibrock, J., & Barde, Y. (1990) · The EMBO Journal · doi:10.1002/j.1460-2075.1990.tb07423.x · Cited by 1,039
Multiple promoters direct tissue-specific expression of the rat BDNF gene
Timmusk, T., Palm, K., Metsis, M., Reintam, T., Paalme, V., Saarma, M., & Persson, H. (1993) · Neuron · doi:10.1016/0896-6273(93)90335-o · Cited by 858
Ernfors, P., Wetmore, C., Olson, L., & Persson, H. (1990) · Neuron · doi:10.1016/0896-6273(90)90090-3 · Cited by 819
BDNF: A key regulator for protein synthesis-dependent LTP and long-term memory?
Lü, Y., Christian, K. M., & Lu, B. (2007) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2007.08.018 · Cited by 807
Making memories last: the synaptic tagging and capture hypothesis
Redondo, R. L., & Morris, R. G. M. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn2963 · Cited by 792
Brain-derived Neurotrophic Factor Is Stored in Human Platelets and Released by Agonist Stimulation
Fujimura, H., Chen, R., Nakamura, T., Nakahashi, T., Kambayashi, J.-I., Sun, B., Altar, C., & Tandon, N. (2002) · Thrombosis and Haemostasis · doi:10.1055/s-0037-1613072 · Cited by 777
Postsynaptic BDNF‐TrkB signaling in synapse maturation, plasticity, and disease
Yoshii, A., & Constantine‐Paton, M. (2010) · Developmental Neurobiology · doi:10.1002/dneu.20765 · Cited by 744
An, J. J., Gharami, K., Liao, G., Woo, N. H., Lau, A. G., Vanevski, F., Torre, E. R., Jones, K. R., Feng, Y., Lu, B., et al. (2008) · Cell · doi:10.1016/j.cell.2008.05.045 · Cited by 698
Neurotrophin secretion: current facts and future prospects
Leßmann, V., Gottmann, K., & Malcangio, M. (2003) · Progress in Neurobiology · doi:10.1016/s0301-0082(03)00019-4 · Cited by 683
Self-citationSynaptic plasticity at hippocampal mossy fibre synapses
Nicoll, R. A., & Schmitz, D. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1786 · Cited by 653
Protein synthesis and neurotrophin-dependent structural plasticity of single dendritic spines
Tanaka, J.-I., Horiike, Y., Matsuzaki, M., Miyazaki, T., Ellis-Davies, G. C. R., & Kasai, H. (2008) · Science · doi:10.1126/science.1152864 · Cited by 615
Levine, E. S., Dreyfus, C. F., Black, I. B., & Plummer, M. R. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.17.8074 · Cited by 611
Translational Regulatory Mechanisms in Persistent Forms of Synaptic Plasticity
Kelleher, R. J., Govindarajan, A., & Tonegawa, S. (2004) · Neuron · doi:10.1016/j.neuron.2004.09.013 · Cited by 592
Patterson, S. L., Grover, L. M., Schwartzkroin, P. A., & Bothwell, M. (1992) · Neuron · doi:10.1016/0896-6273(92)90067-n · Cited by 555
Long-Term Environmental Enrichment Leads to Regional Increases in Neurotrophin Levels in Rat Brain
Ickes, B. R., Pham, T. M., Sanders, L., Albeck, D. S., Mohammed, A. H. S., & Granholm, A. (2000) · Experimental Neurology · doi:10.1006/exnr.2000.7415 · Cited by 541
Widespread Expression of BDNF But Not NT3 by Target Areas of Basal Forebrain Cholinergic Neurons
PHILLIPS, H. S., Hains, J. M., Laramee, G. R., Rosenthal, A., & Winslow, J. W. (1990) · Science · doi:10.1126/science.1688328 · Cited by 539
The role of neuronal growth factors in neurodegenerative disorders of the human brain
Connor, B. J., & Dragunow, M. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(98)00004-6 · Cited by 538
Synaptic secretion of BDNF after high‐frequency stimulation of glutamatergic synapses
Hartmann, M., Heumann, R., & Leßmann, V. (2001) · The EMBO Journal · doi:10.1093/emboj/20.21.5887 · Cited by 528
Self-citationMichael, G. J., Averill, S., Nitkunan, A., Rattray, M., Bennett, D., Yan, Q., & Priestley, J. V. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-21-08476.1997 · Cited by 512
Mechanism of TrkB-Mediated Hippocampal Long-Term Potentiation
Minichiello, L., Calella, A. M., Medina, D. L., Bonhoeffer, T., Klein, R., & Korte, M. (2002) · Neuron · doi:10.1016/s0896-6273(02)00942-x · Cited by 506
Expression of brain-derived neurotrophic factor protein in the adult rat central nervous system
Yan, Q., Rosenfeld, R. D., Matheson, C. R., Hawkins, N., Lopez, O. T., Bennett, L., & Welcher, A. A. (1997) · Neuroscience · doi:10.1016/s0306-4522(96)00613-6 · Cited by 498
Neurotrophins and Time: Different Roles for TrkB Signaling in Hippocampal Long-Term Potentiation
Kang, H., Welcher, A. A., Shelton, D., & Schuman, E. M. (1997) · Neuron · doi:10.1016/s0896-6273(00)80378-5 · Cited by 481
Huang, Y.-Y., & Kandel, E. R. (1994) · Learning & Memory · doi:10.1101/lm.1.1.74 · Cited by 477
Pozzo‐Miller, L. D., Gottschalk, W., Zhang, L., McDermott, K., Du, J., Gopalakrishnan, R., Oho, C., Sheng, Z., & Lu, B. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-12-04972.1999 · Cited by 476
Trang, T., Beggs, S., Wan, X., & Salter, M. W. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.5714-08.2009 · Cited by 474
A history of spike-timing-dependent plasticity
Markram, H. (2011) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2011.00004 · Cited by 454
Yang, J., Siao, C.-J., Nagappan, G., Marinic, T., Jing, D., McGrath, K., Chen, Z.-Y., Mark, W., Tessarollo, L., Lee, F. S., et al. (2009) · Nature Neuroscience · doi:10.1038/nn.2244 · Cited by 449
Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl− homeostasis
Ferrini, F., Trang, T., Mattioli, T.-A. M., Laffray, S., Del’Guidice, T., Lorenzo, L.-É., Castonguay, A., Doyon, N., Zhang, W., Godin, A. G., et al. (2013) · Nature Neuroscience · doi:10.1038/nn.3295 · Cited by 441
Kerr, B. J., Bradbury, E. J., Bennett, D., Trivedi, P. M., Dassan, P., French, J., Shelton, D., McMahon, S. B., & Thompson, S. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-12-05138.1999 · Cited by 439
Dopamine Receptor Activation Is Required for Corticostriatal Spike-Timing-Dependent Plasticity
Pawlak, V., & Kerr, J. N. D. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.4402-07.2008 · Cited by 430
Neuromodulators control the polarity of spike-timing-dependent synaptic plasticity
Seol, G. H., Ziburkus, J., Huang, S., Song, L., Kim, I. T., Takamiya, K., Huganir, R. L., Lee, H.-K., & Kirkwood, A. (2007) · Neuron · doi:10.1016/j.neuron.2007.08.013 · Cited by 429
Bałkowiec, A., & Katz, D. M. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-23-10399.2002 · Cited by 411
Xu, B., Gottschalk, W., Chow, A., Wilson, R. I., Schnell, E., Zang, K., Wang, D., Nicoll, R. A., Lu, B., & Reichardt, L. F. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-18-06888.2000 · Cited by 404
Shelton, D., Sutherland, J. S., Gripp, J. T., Camerato, T., Armanini, M. P., Phillips, H., Carroll, K., Spencer, S., & Levinson, A. D. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-01-00477.1995 · Cited by 403
Wetmore, C., Ernfors, P., Persson, H., & Olson, L. (1990) · Experimental Neurology · doi:10.1016/0014-4886(90)90068-4 · Cited by 370
Spike-Timing-Dependent Plasticity: A Comprehensive Overview
Markram, H., Gerstner, W., & Sjöström, P. J. (2012) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2012.00002 · Cited by 367
BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons
Dieni, S., Matsumoto, T., Dekkers, M. P. J., Rauskolb, S., Ionescu, M. S., Deogracias, R., Gundelfinger, E. D., Kojima, M., Nestel, S., Frotscher, M., et al. (2012) · The Journal of Cell Biology · doi:10.1083/jcb.201201038 · Cited by 362
Mechanisms, locations, and kinetics of synaptic BDNF secretion: An update
Leßmann, V., & Brigadski, T. (2009) · Neuroscience Research · doi:10.1016/j.neures.2009.06.004 · Cited by 360
Self-citationPang, P. T., & Lu, B. (2004) · Ageing Research Reviews · doi:10.1016/j.arr.2004.07.002 · Cited by 356
Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF
Matsumoto, T., Rauskolb, S., Polack, M., Klose, J., Kolbeck, R., Körte, M., & Barde, Y. (2008) · Nature Neuroscience · doi:10.1038/nn2038 · Cited by 355
Activity-Dependent Transfer of Brain-Derived Neurotrophic Factor to Postsynaptic Neurons
Kohara, K., Kitamura, A., Morishima, M., & Tsumoto, T. (2001) · Science · doi:10.1126/science.1057415 · Cited by 354
Natural patterns of activity and long-term synaptic plasticity
Paulsen, O. (2000) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00076-3 · Cited by 354
Korte, M., Griesbeck, O., Gravel, C., Carroll, P., Staiger, V, Thoenen, H., & Bonhoeffer, T. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.22.12547 · Cited by 351
Zakharenko, S. S., Patterson, S. L., Dragatsis, I., Zeitlin, S. O., Siegelbaum, S. A., Kandel, E. R., & Morozov, A. (2003) · Neuron · doi:10.1016/s0896-6273(03)00543-9 · Cited by 334
Patterson, S. L., Pittenger, C., Morozov, A., Martin, K. C., Scanlin, H., Drake, C., & Kandel, E. R. (2001) · Neuron · doi:10.1016/s0896-6273(01)00443-3 · Cited by 334
Long-term potentiation in the amygdala: A cellular mechanism of fear learning and memory
Sigurdsson, T., Doyère, V., Cain, C. K., & LeDoux, J. E. (2006) · Neuropharmacology · doi:10.1016/j.neuropharm.2006.06.022 · Cited by 333
Bałkowiec, A., & Katz, D. M. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-19-07417.2000 · Cited by 330
Activity-Dependent Dendritic Targeting of BDNF and TrkB mRNAs in Hippocampal Neurons
Tongiorgi, E., Righi, M., & Cattaneo, A. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-24-09492.1997 · Cited by 328
Goodman, L. J., Valverde, J., Lim, F., Geschwind, M. D., Federoff, H. J., Geller, A. I., & Hefti, F. F. (1996) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.1996.0017 · Cited by 323
BDNF signaling in the formation, maturation and plasticity of glutamatergic and GABAergic synapses
Gottmann, K., Mittmann, T., & Leßmann, V. (2009) · Experimental Brain Research · doi:10.1007/s00221-009-1994-z · Cited by 314
Self-citationPKM-ζ is not required for hippocampal synaptic plasticity, learning and memory
Volk, L. J., Bachman, J. L., Johnson, R., Yu, Y., & Huganir, R. L. (2013) · Nature · doi:10.1038/nature11802 · Cited by 310
Blockade of Endogenous Ligands of TrkB Inhibits Formation of Ocular Dominance Columns
Cabelli, R. J., Shelton, D. L., Segal, R. A., & Shatz, C. J. (1997) · Neuron · doi:10.1016/s0896-6273(00)80348-7 · Cited by 306
Barco, A., Patterson, S., Alarcon, J. M., Gromova, P., Mata-Roig, M., Morozov, A., & Kandel, E. R. (2005) · Neuron · doi:10.1016/j.neuron.2005.09.005 · Cited by 305
Lever, I. J., Bradbury, E. J., Cunningham, J. R., Adelson, D. W., Jones, M. G., McMahon, S. B., Marvizón, J. C. G., & Malcangio, M. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-12-04469.2001 · Cited by 300
BDNF promotes differentiation and maturation of adult-born neurons through GABAergic transmission
Waterhouse, E. G., An, J. J., Orefice, L. L., Baydyuk, M., Liao, G.-Y., Zheng, K., Lu, B., & Xu, B. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.0709-12.2012 · Cited by 287
Brain-Derived Neurotrophic Factor Enhances Long-Term Potentiation in Rat Visual Cortex
Akaneya, Y., Tsumoto, T., Kinoshita, S., & Hatanaka, H. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-17-06707.1997 · Cited by 286
Griesbach, G. S., Hovda, D. A., & Gómez‐Pinilla, F. (2009) · Brain Research · doi:10.1016/j.brainres.2009.06.045 · Cited by 282
Control of extracellular cleavage of ProBDNF by high frequency neuronal activity
Nagappan, G., Zaitsev, E. N., Senatorov, V. V., Yang, J., Hempstead, B. L., & Lu, B. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0807322106 · Cited by 278
Clarkson, A. N., Overman, J. J., Zhong, S., Mueller, R., Lynch, G., & Carmichael, S. T. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.5780-10.2011 · Cited by 276
Zinc-Mediated Transactivation of TrkB Potentiates the Hippocampal Mossy Fiber-CA3 Pyramid Synapse
Huang, Y. Z., Pan, E., Xiong, Z., & McNamara, J. O. (2008) · Neuron · doi:10.1016/j.neuron.2007.11.026 · Cited by 275
Associative long-term potentiation in hippocampal slices.
Barrionuevo, G., & Brown, T. H. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.23.7347 · Cited by 273
A role for BDNF in the late-phase of hippocampal long-term potentiation
Körte, M., Kang, H., Bonhoeffer, T., & Schuman, E. M. (1998) · Neuropharmacology · doi:10.1016/s0028-3908(98)00035-5 · Cited by 269
Neurotrophin release by neurotrophins: Implications for activity-dependent neuronal plasticity
Canossa, M., Griesbeck, O., Berninger, B., Campana, G., Kolbeck, R., & Thoenen, H. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.24.13279 · Cited by 269
Matsuda, N., Lü, H., Fukata, Y., Noritake, J., Gao, H., Mukherjee, S., Nemoto, T., Fukata, M., & Poo, M. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.1863-09.2009 · Cited by 268
Prkcz null mice show normal learning and memory
Lee, A. M., Kanter, B. R., Wang, D., Lim, J. P., Zou, M. E., Qiu, C., McMahon, T., Dadgar, J., Fischbach-Weiss, S., & Messing, R. O. (2013) · Nature · doi:10.1038/nature11803 · Cited by 259
Caldeira, M. V., Melo, C. V., Pereira, D. B., Carvalho, R., Correia, S. S., Backos, D. S., Carvalho, A. L., Esteban, J. A., & Duarte, C. B. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m700607200 · Cited by 251
Aicardi, G., Argilli, E., Cappello, S., Santi, S., Riccio, M., Thoenen, H., & Canossa, M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0406960101 · Cited by 246
Gomes, C. A., Ferreira, R., George, J., Sanches, R., Rodrigues, D. I., Gonçalves, N., & Cunha, R. A. (2013) · Journal of Neuroinflammation · doi:10.1186/1742-2094-10-16 · Cited by 244
Relative Contribution of Endogenous Neurotrophins in Hippocampal Long-Term Potentiation
Chen, G., Kolbeck, R., Barde, Y., Bonhoeffer, T., & Kossel, A. H. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-18-07983.1999 · Cited by 243
Zhang, J.-C., Lau, P.-M., & Bi, G. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0900546106 · Cited by 241
Lau, A. G., Irier, H. A., Gu, J., Tian, D., Ku, L., Liu, G., Xia, M., Fritsch, B., Zheng, J. Q., Dingledine, R. J., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1002929107 · Cited by 225
Amaral, M. D., & Pozzo-Miller, L. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.5499-06.2007 · Cited by 214
Synaptotagmin-IV modulates synaptic function and long-term potentiation by regulating BDNF release
Dean, C., Liu, H., Dunning, F. M., Chang, P. Y., Jackson, M. B., & Chapman, E. R. (2009) · Nature Neuroscience · doi:10.1038/nn.2315 · Cited by 214
Barg, S., Olofsson, C. S., Schriever-Abeln, J., Wendt, A., Gebre-Medhin, S., Renström, E., & Rorsman, P. (2002) · Neuron · doi:10.1016/s0896-6273(02)00563-9 · Cited by 210
Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin
Liao, G., An, J. J., Gharami, K., Waterhouse, E. G., Vanevski, F., Jones, K. R., & Xu, B. (2012) · Nature Medicine · doi:10.1038/nm.2687 · Cited by 208
Wetmore, C., Olson, L., & Bean, A. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-03-01688.1994 · Cited by 207
Kolarow, R., Brigadski, T., & Lessmann, V. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.0692-07.2007 · Cited by 203
Self-citationSakata, K., Woo, N. H., Martinowich, K., Greene, J. S., Schloesser, R. J., Shen, L., & Lu, B. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811431106 · Cited by 200
Sajikumar, S. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.1104-05.2005 · Cited by 199
Gärtner, A., & Staiger, V. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.092129699 · Cited by 195
Redondo, R. L., Okuno, H., Spooner, P. A., Frenguelli, B. G., Bito, H., & Morris, R. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.3140-09.2010 · Cited by 186
Lou, H., Kim, S., Zaitsev, E. N., SNELL, C. R., Lu, B., & Loh, Y. P. (2005) · Neuron · doi:10.1016/j.neuron.2004.12.037 · Cited by 185
Lai, K., Wong, A. S. L., Cheung, M. C., Xu, P., Liang, Z., Lok, K.-C., Xie, H., Palko, M. E., Yung, W., Tessarollo, L., et al. (2012) · Nature Neuroscience · doi:10.1038/nn.3237 · Cited by 175
Brain-derived neurotrophic factor and control of synaptic consolidation in the adult brain
Soule, J. D., Messaoudi, E., & Bramham, C. R. (2006) · Biochemical Society Transactions · doi:10.1042/bst0340600 · Cited by 174
Artola, A., & Singer, W. (1990) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1990.tb00417.x · Cited by 173
Uptake and recycling of pro-BDNF for transmitter-induced secretion by cortical astrocytes
Bergami, M., Santi, S., Formaggio, E., Cagnoli, C. M., Verderio, C., Blum, R., Berninger, B., Matteoli, M., & Canossa, M. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200806137 · Cited by 173
Jakawich, S. K., Nasser, H. B., Strong, M. J., McCartney, A. J., Perez, A. S., Rakesh, N., Carruthers, C. J. L., & Sutton, M. A. (2010) · Neuron · doi:10.1016/j.neuron.2010.11.034 · Cited by 171
Haubensak, W. E., Narz, F., Heumann, R., & Lemann, V. (1998) · Journal of Cell Science · doi:10.1242/jcs.111.11.1483 · Cited by 170
Self-citationMu, Y., & Poo, M.-M. (2006) · Neuron · doi:10.1016/j.neuron.2006.03.009 · Cited by 164
Slack, S. E., Pezet, S., McMahon, S. B., Thompson, S., & Malcangio, M. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03656.x · Cited by 159
Pattwell, S. S., Bath, K. G., Perez-Castro, R., Lee, F. S., Chao, M. V., & Ninan, I. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.5205-11.2012 · Cited by 156
Tongiorgi, E., Armellin, M., Giulianini, P. G., Bregola, G., Zucchini, S., Paradiso, B., Steward, O., Cattaneo, A., & Simonato, M. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.5471-03.2004 · Cited by 143
Lin, Y., Ro, L. S., Wang, H., & Chen, J. (2011) · Journal of Neuroinflammation · doi:10.1186/1742-2094-8-126 · Cited by 143
Kuczewski, N., Porcher, C., Ferrand, N., Fiorentino, H., Pellegrino, C., Kolarow, R., Leßmann, V., Medina, I., & Gaïarsa, J. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1673-08.2008 · Cited by 142
Self-citationBrigadski, T., Hartmann, M., & Leßmann, V. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.1776-05.2005 · Cited by 142
Self-citationWetmore, C., Cao, Y. H., Pettersson, R. F., & Olson, L. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.21.9843 · Cited by 141
Schmidt‐Kastner, R., Wetmore, C., & OLSON, L. (1996) · Neuroscience · doi:10.1016/0306-4522(96)00093-0 · Cited by 139
Gärtner, A., Polnau, D. G., Staiger, V., Sciarretta, C., Minichiello, L., Thoenen, H., Bonhoeffer, T., & Körte, M. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3792-05.2006 · Cited by 138
Tyler, W. J., Zhang, X., Hartman, K. N., Winterer, J., Müller, W. S., Stanton, P. K., & Pozzo‐Miller, L. D. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.111310 · Cited by 137
Lü, H., Cheng, P., Lim, B. K., Khoshnevisrad, N., & Poo, M. (2010) · Neuron · doi:10.1016/j.neuron.2010.08.012 · Cited by 137
Ying, Z., Roy, R. R., Zhong, H., Zdunowski, S., Edgerton, V. R., & Gómez‐Pinilla, F. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.06.057 · Cited by 136
Anterograde Axonal Transport, Transcytosis, and Recycling of Neurotrophic Factors
von Bartheld, C. S., Wang, X., & Butowt, R. (2001) · Molecular Neurobiology · doi:10.1385/mn:24:1-3:001 · Cited by 135
TrkB as a Potential Synaptic and Behavioral Tag
Lü, Y., Ji, Y., Ganesan, S., Schloesser, R. J., Martinowich, K., Sun, M., Mei, F., Chao, M. V., & Lu, B. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.2707-11.2011 · Cited by 133
Noxious Stimulation Induces Trk Receptor and Downstream ERK Phosphorylation in Spinal Dorsal Horn
Pezet, S. (2002) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.2002.1205 · Cited by 133
Ramachandran, B., & Frey, J. U. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.2045-09.2009 · Cited by 133
Kojima, M., Takei, N., Numakawa, T., Ishikawa, Y., Suzuki, S., Matsumoto, T., Katoh‐Semba, R., Nawa, H., & Hatanaka, H. (2001) · Journal of Neuroscience Research · doi:10.1002/jnr.1080 · Cited by 130
Pro-BDNF–induced synaptic depression and retraction at developing neuromuscular synapses
Yang, F., Je, H.-S., Ji, Y., Nagappan, G., Hempstead, B., & Lu, B. (2009) · Journal of Cell Biology · doi:10.1083/jcb.200811147 · Cited by 130
Timing and efficacy of transmitter release at mossy fiber synapses in the hippocampal network
Bischofberger, J., Engel, D., Frotscher, M., & Jónás, P. (2006) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-006-0093-2 · Cited by 129
Detection of Brain-derived Neurotrophic Factor in a Vesicular Fraction of Brain Synaptosomes
Fawcett, J. P., Aloyz, R. S., McLean, J. H., Pareek, S., Miller, F. D., McPherson, P. S., & Murphy, R. A. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.14.8837 · Cited by 127
Novel presynaptic mechanisms for coincidence detection in synaptic plasticity
Duguid, I., & Sjöström, P. J. (2006) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2006.05.008 · Cited by 127
Sajikumar, S., & Körte, M. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1016849108 · Cited by 126
Kohara, K., Yasuda, H., Huang, Y. Y., Adachi, N., Sohya, K., & Tsumoto, T. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1943-07.2007 · Cited by 124
Anterograde transport of endogenous brain-derived neurotrophic factor in hippocampal mossy fibers
Smith, M. A., Zhang, L., Lyons, W. E., & Mamounas, L. A. (1997) · Neuroreport · doi:10.1097/00001756-199705260-00008 · Cited by 122
Presynaptic BDNF Promotes Postsynaptic Long-Term Potentiation in the Dorsal Striatum
Jia, Y., Gall, C. M., & LYNCH, G. S. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.3310-10.2010 · Cited by 122
Righi, M., Tongiorgi, E., & Cattaneo, A. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-09-03165.2000 · Cited by 121
Fortin, D. A., Srivastava, T., Dwarakanath, D., Pierre, P., Nygaard, S., Derkach, V. A., & Soderling, T. R. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.6034-11.2012 · Cited by 120
Itami, C., Kimura, F., Kohno, T., Matsuoka, M., Ichikawa, M., Tsumoto, T., & Nakamura, S. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2131948100 · Cited by 120
Ou, L.-C., & Gean, P. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300830 · Cited by 120
Human Immunodeficiency Virus Type 1 Alters Brain-Derived Neurotrophic Factor Processing in Neurons
Bachis, A., Avdoshina, V., Zecca, L., Parsadanian, M., & Mocchetti, I. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.0865-12.2012 · Cited by 117
Tongiorgi, E. (2008) · Neuroscience Research · doi:10.1016/j.neures.2008.04.013 · Cited by 116
Chourbaji, S., Brandwein, C., & Gass, P. (2010) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.07.003 · Cited by 114
Buldyrev, I., Tanner, N. M., Hsieh, H., Dodd, E. G., Nguyen, L. T., & Bałkowiec, A. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.04161.x · Cited by 114
Mohajerani, M. H., Sivakumaran, S., Zacchi, P., Aguilera, P. A., & Cherubini, E. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0704533104 · Cited by 113
Noga, O., Englmann, C., Hanf, G., Grützkau, A., Seybold, J., & Kunkel, G. (2003) · Clinical & Experimental Allergy · doi:10.1046/j.1365-2222.2003.01586.x · Cited by 113
Munson, J. B., Shelton, D. L., & McMahon, S. B. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-01-00470.1997 · Cited by 111
Hippocampal neurons recycle BDNF for activity‐dependent secretion and LTP maintenance
Santi, S., Cappello, S., Riccio, M., Bergami, M., Aicardi, G., Schenk, U., Matteoli, M., & Canossa, M. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601303 · Cited by 110
Canossa, M., Giordano, E., Cappello, S., Guarnieri, C., & Ferri, S. S. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.042504299 · Cited by 110
Jean, Y. Y., Lercher, L. D., & Dreyfus, C. F. (2008) · Neuron Glia Biology · doi:10.1017/s1740925x09000052 · Cited by 107
Canossa, M., Gärtner, A., Campana, G., Inagaki, N., & Thoenen, H. (2001) · The EMBO Journal · doi:10.1093/emboj/20.7.1640 · Cited by 105
Memory maintenance by PKMζ — an evolutionary perspective
Sacktor, T. C. (2012) · Molecular Brain · doi:10.1186/1756-6606-5-31 · Cited by 102
Su, C., Cunningham, R. L., Rybalchenko, N., & Singh, M. (2012) · Endocrinology · doi:10.1210/en.2011-2177 · Cited by 101
GABA B Receptor Activation Triggers BDNF Release and Promotes the Maturation of GABAergic Synapses
Fiorentino, H., Kuczewski, N., Diabira, D., Ferrand, N., Pangalos, M. N., Porcher, C., & Gaïarsa, J. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.3587-09.2009 · Cited by 100
A caged Ab reveals an immediate/instructive effect of BDNF during hippocampal synaptic potentiation
Kossel, A. H., Cambridge, S. B., Wagner, U., & Bonhoeffer, T. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.251326998 · Cited by 100
Madara, J. C., & Levine, E. S. (2008) · Journal of Neurophysiology · doi:10.1152/jn.90880.2008 · Cited by 98
Jung, S., Kim, J., Kwon, O. B., Jung, J. H., An, K., Jeong, A. Y., Lee, C. J., Choi, Y., Bailey, C. H., Kandel, E. R., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1001084107 · Cited by 97
Immunohistochemical Visualization of Brain‐derived Neurotrophic Factor in the Rat Brain
Dugich‐Djordjevic, M. M., Peterson, C. M., Isono, F., Ohsawa, F., Widmer, H. R., Denton, T. L., Bennett, G. L., & Hefti, F. F. (1995) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1995.tb00703.x · Cited by 97
Gangliosides Activate Trk Receptors by Inducing the Release of Neurotrophins
Rabin, S. J., Bachis, A., & Mocchetti, I. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m203240200 · Cited by 91
Rind, H. B., Butowt, R., & von Bartheld, C. S. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.4322-04.2005 · Cited by 91
Shinoda, Y., Sadakata, T., Nakao, K., Katoh‐Semba, R., Kinameri, E., Furuya, A., Yanagawa, Y., Hirase, H., & Furuichi, T. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1012220108 · Cited by 89
Salio, C., Averill, S., Priestley, J. V., & Merighi, A. (2007) · Developmental Neurobiology · doi:10.1002/dneu.20358 · Cited by 89
Nakajima, K., Tohyama, Y., Kohsaka, S., & Kurihara, T. (2002) · Journal of Neurochemistry · doi:10.1046/j.0022-3042.2001.00752.x · Cited by 88
Synaptic plasticity: Going through phases with LTP
Huang, E. P. (1998) · Current Biology · doi:10.1016/s0960-9822(98)70219-2 · Cited by 87
Sivakumaran, S., Mohajerani, M. H., & Cherubini, E. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.5019-08.2009 · Cited by 84
Butowt, R., & von Bartheld, C. S. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-22-08915.2001 · Cited by 83
Secretion of brain‐derived neurotrophic factor from brain microvascular endothelial cells
Wang, H., Ward, N., Boswell, M., & Katz, D. M. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04682.x · Cited by 81
Barco, Á., de Armentia, M. L., & Alarcón, J. M. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.01.002 · Cited by 81
Sajikumar, S., Li, Q., Abraham, W. C., & Xiao, Z. (2009) · Learning & Memory · doi:10.1101/lm.1255909 · Cited by 80
Ultrastructural localization of brain-derived neurotrophic factor in rat primary sensory neurons
Luo, X., Rush, R. A., & Zhou, X. (2001) · Neuroscience Research · doi:10.1016/s0168-0102(00)00238-8 · Cited by 79
Postsynaptic BDNF signalling regulates long‐term potentiation at thalamo‐amygdala afferents
Meis, S., Endres, T., & Leßmann, V. (2011) · The Journal of Physiology · doi:10.1113/jphysiol.2011.220434 · Cited by 78
Self-citationBabu, H. (2009) · Frontiers in Neuroscience · doi:10.3389/neuro.22.001.2009 · Cited by 78
Wu, L. L., Fan, Y., Li, S., Li, X., & Zhou, X. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.073197 · Cited by 78
Skucas, V., Duffy, Á. M., Harte-Hargrove, L., Magagna-Poveda, A., Radman, T., Chakraborty, G., Schroeder, C., MacLusky, N., & Scharfman, H. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.3857-12.2013 · Cited by 78
Ou, L.-C., Yeh, S.-H., & Gean, P. (2009) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2009.12.003 · Cited by 77
Miladi‐Gorji, H., Rashidy‐Pour, A., Fathollahi, Y., Akhavan, M. M., Semnanian, S., & Safari, M. (2011) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2011.08.001 · Cited by 76
The activity requirements for spike timing-dependent plasticity in the hippocampus
Buchanan, K. A. (2010) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2010.00011 · Cited by 76
Exercise normalizes levels of MAG and Nogo‐A growth inhibitors after brain trauma
Chytrova, G., Ying, Z., & Gómez‐Pinilla, F. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05982.x · Cited by 75
Huntley, G. W., Benson, D. L., Jones, E. G., & Isackson, P. J. (1992) · Developmental Brain Research · doi:10.1016/0165-3806(92)90103-4 · Cited by 75
GABAA Receptor Blockade Enhances Memory Consolidation by Increasing Hippocampal BDNF Levels
Kim, D. H., Kim, J. M., Park, S. J., Cai, M., Liu, X., Lee, S., Shin, C. Y., & Ryu, J. H. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2011.189 · Cited by 75
Matrix-Dependent Local Retention of Secretory Vesicle Cargo in Cortical Neurons
de Wit, J., Toonen, R. F. G., & Verhage, M. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.3931-08.2009 · Cited by 75
Sadakata, T., Shinoda, Y., Oka, M., Sekine, Y., Sato, Y., Saruta, C., Miwa, H., Tanaka, M., Itohara, S., & Furuichi, T. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1210055109 · Cited by 75
BDNF Facilitates L-LTP Maintenance in the Absence of Protein Synthesis through PKMζ
Mei, F., Nagappan, G., Ke, Y., Sacktor, T. C., & Lu, B. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021568 · Cited by 73
Single-Cell Characterization of Retrograde Signaling by Brain-Derived Neurotrophic Factor
Magby, J. P., Bi, C., Chen, Z.-Y., Lee, F. S., & Plummer, M. R. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.4576-06.2006 · Cited by 72
Xia, X., Leßmann, V., & Martin, T. F. J. (2008) · Journal of Cell Science · doi:10.1242/jcs.034603 · Cited by 70
Self-citationAlder, J., Thakker‐Varia, S., Crozier, R. A., Shaheen, A., Plummer, M. R., & Black, I. B. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.2970-04.2005 · Cited by 70
NMDA receptor–dependent metaplasticity at hippocampal mossy fiber synapses
Rebola, N., Carta, M., Lanore, F., Blanchet, C., & Mulle, C. (2011) · Nature Neuroscience · doi:10.1038/nn.2809 · Cited by 68
Ma, L., Wang, D., Zhang, T.-Y., Yu, H. J., Wang, Y., Huang, S., Lee, F. S., & Chen, Z.-Y. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.5348-10.2011 · Cited by 66
Tamura, S., Suzuki, H., Hirowatari, Y., Hatase, M., Nagasawa, A., Matsuno, K., Kobayashi, S., & Moriyama, T. (2011) · Thrombosis Research · doi:10.1016/j.thromres.2011.06.002 · Cited by 64
Co-infusion with a TrkB-Fc Receptor Body Carrier Enhances BDNF Distribution in the Adult Rat Brain
Croll, S. D., Chesnutt, C. R., Rudge, J. S., Acheson, A. L., RYAN, T. E., Siuciak, J. A., DiStefano, P. S., Wiegand, S. J., & Lindsay, R. M. (1998) · Experimental Neurology · doi:10.1006/exnr.1998.6836 · Cited by 63
Vazquez-Sanroman, D. B., Sanchis‐Segura, C., Toledo‐Cárdenas, M. R., Hernández‐Aguilar, M. E., Manzo, J. G., & Miquel, M. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.12.047 · Cited by 63
Li, Y., Calfa, G. D., Inoue, T., Amaral, M. D., & Pozzo‐Miller, L. D. (2010) · Journal of Neurophysiology · doi:10.1152/jn.01140.2009 · Cited by 63
Activation of Adenosine A2A Receptor Up-Regulates BDNF Expression in Rat Primary Cortical Neurons
Jeon, S. J., Rhee, S. Y., Ryu, J. H., Cheong, J. H., Kwon, K.-J., Yang, S., Park, S. H., Lee, J., Kim, H. Y., Han, S., et al. (2011) · Neurochemical Research · doi:10.1007/s11064-011-0550-y · Cited by 62
Li, C., Dabrowska, J., Hazra, R., & Rainnie, D. G. (2011) · PLoS ONE · doi:10.1371/journal.pone.0026065 · Cited by 62
Long-range retrograde spread of LTP and LTD from optic tectum to retina
Du, J., Wei, H., Wang, Z., Wong, S. T., & Poo, M. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0910659106 · Cited by 61
Wu, Y. J., Krüttgen, A., Möller, J. C., Shine, D., Chan, J. R., Shooter, E. M., & Cosgaya, J. M. (2004) · Journal of Neuroscience Research · doi:10.1002/jnr.20048 · Cited by 60
Effects of BDNF and NT-3 on Development of Ia/Motoneuron Functional Connectivity in Neonatal Rats
Seebach, B. S., Arvanov, V. L., & Mendell, L. M. (1999) · Journal of Neurophysiology · doi:10.1152/jn.1999.81.5.2398 · Cited by 60
Kokaia, M., Ferencz, I., Leanza, G., Elmér, E., METSIS, M. L., Kokaia, Z., Wiley, R. G., & Lindvall, O. (1996) · Neuroscience · doi:10.1016/0306-4522(95)00384-3 · Cited by 58
Dean, C., Liu, H., Staudt, T., Stahlberg, M. A., Vingill, S., Bückers, J., Kamin, D., Engelhardt, J., Jackson, M. B., Hell, S. W., et al. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.4515-11.2012 · Cited by 58
Huie, J. R., Garraway, S. M., Baumbauer, K. M., Hoy, K. C., Beas, B. S., Montgomery, K. S., Bizon, J. L., & Grau, J. W. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.10.028 · Cited by 58
Tongiorgi, E., Domenici, L., & Simonato, M. (2005) · Molecular Neurobiology · doi:10.1385/mn:33:1:017 · Cited by 58
The effects of amyloid-β42 oligomer on the proliferation and activation of astrocytes in vitro
Hou, L., Liu, Y., Wang, X., Ma, H., He, J., Zhang, Y., Yu, C.-H., Guan, W., & Ma, Y.-H. (2011) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-011-9439-y · Cited by 57
Schildt, S., Endres, T., Leßmann, V., & Edelmann, E. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.03.041 · Cited by 57
Self-citation
Cited by
Sorted by citations
Cryan, J. F., O'Riordan, K. J., Cowan, C. S. M., Sandhu, K. V., Bastiaanssen, T. F. S., Boehme, M., Codagnone, M. G., Cussotto, S., Fulling, C., Golubeva, A. V., et al. (2019) · Physiological Reviews · doi:10.1152/physrev.00018.2018 · Cited by 5,286
BDNF: A Key Factor with Multipotent Impact on Brain Signaling and Synaptic Plasticity
Kowiański, P., Lietzau, G., Czuba, E., Waśkow, M., Steliga, A., & Moryś, J. (2018) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-017-0510-4 · Cited by 1,359
Colucci-D’Amato, L., Speranza, L., & Volpicelli, F. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21207777 · Cited by 991
Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on Neuroinflammation
Lima Giacobbo, B., Doorduin, J., Klein, H. C., Dierckx, R. A. J. O., Bromberg, E., & de Vries, E. F. J. (2019) · Molecular Neurobiology · doi:10.1007/s12035-018-1283-6 · Cited by 750
BDNF and Hippocampal Synaptic Plasticity
Leal, G., Bramham, C. R., & Duarte, C. B. (2017) · Vitamins and Hormones · doi:10.1016/bs.vh.2016.10.004 · Cited by 425
Metadata
- Authors
- Edelmann, E., Leßmann, V., & Brigadski, T.
- Affiliations
- Otto-von-Guericke-Universität Magdeburg (DE)
- Center for Behavioral Brain Sciences (DE)
- Corresponding author
- Leßmann, Volkmar
- Venue
- Neuropharmacology
- Publisher
- Elsevier BV
- Published
- 2014-01
- Volume
- 76
- Pages
- 610-627
- ISSN
- 0028-3908 (ISSN-L)
- OpenAlex
- W1973883693
- Cited by
- 248
- References
- 246
- Citations by year
- 2026: 9 · 2025: 10 · 2024: 23 · 2023: 23 · 2022: 19 · 2021: 24 · 2020: 18 · 2019: 22 · 2018: 23 · 2017: 20 · 2016: 24 · 2015: 12 · 2014: 14
- FWCI
- 1.93
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuropharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Nerve injury and regeneration
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- brain-derived neurotrophic factor, BDNF secretion, synaptic plasticity, long-term potentiation, spike-timing-dependent plasticity, presynaptic neurotransmitter release, postsynaptic effects, central nervous system
- MeSH terms
- Animals, Neuronal Plasticity, Presynaptic Terminals, Brain-Derived Neurotrophic Factor, Post-Synaptic Density
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
