Effects of widely used drugs on micronutrients: A story rarely told
Open accessAbstract
Vitamins and trace elements are essential to the body, however, deficiencies are frequently observed in the general population. Diet is mostly responsible for these deficiencies but drugs also may play a significant role by influencing their metabolism. These effects are rarely assessed in clinical practice, in part because of limited data available in the literature. Drug-induced micronutrient depletions, however, may be the origin of otherwise unexplained symptoms that might sometimes influence medication compliance. We present various examples of widely prescribed drugs that can precipitate micronutrient deficiencies. This review aims at sensitizing physicians on drug-micronutrient interactions. High-risk population groups also are presented and supplementation protocols are suggested.
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- Authors
- Samaras, D., Samaras, N., Lang, P.-O., Genton, L., Frangos, E., & Pichard, C.
- Affiliations
- University Hospital of Geneva (CH)
- University of Geneva (CH)
- Clinique de Genolier (CH)
- Corresponding author
- Pichard, Claude
- ORCID
- Venue
- Nutrition
- Publisher
- Elsevier BV
- Published
- 2013-04
- Volume
- 29
- Issue
- 4
- Pages
- 605-610
- ISSN
- 0899-9007 (ISSN-L)
- OpenAlex
- W1994444904
- Cited by
- 36
- References
- 78
- Citations by year
- 2026: 4 · 2025: 3 · 2024: 2 · 2023: 2 · 2022: 2 · 2021: 1 · 2020: 3 · 2019: 3 · 2018: 4 · 2017: 2 · 2016: 3 · 2015: 4 · 2014: 2 · 2013: 1
- FWCI
- 0.38
- Type
- journal article
- Language
- en
- Open access
- Licence
- Locations
- Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Archive ouverte UNIGE (University of Geneva) (submittedVersion, cc-by)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Trace Elements in Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutrition and Health Studies
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Keywords
- micronutrient deficiency, vitamins, trace elements, medication adherence, supplementation, vulnerable populations, drug metabolism
- MeSH terms
- Animals, Deficiency Diseases, Humans, Risk, Food-Drug Interactions, Micronutrients, Dietary Supplements, Prescription Drugs
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