Cited by 36Trace Elements in HealthNutrition and Health StudiesNutrition and Health in Aging

Effects of widely used drugs on micronutrients: A story rarely told

Open access
Samaras, Dimitrios, Samaras, Nikolaos, Lang, Pierre-Olivier, Genton, Laurence, Frangos, Emilia, Pichard, Claude·2013·Nutrition

Abstract

Vitamins and trace elements are essential to the body, however, deficiencies are frequently observed in the general population. Diet is mostly responsible for these deficiencies but drugs also may play a significant role by influencing their metabolism. These effects are rarely assessed in clinical practice, in part because of limited data available in the literature. Drug-induced micronutrient depletions, however, may be the origin of otherwise unexplained symptoms that might sometimes influence medication compliance. We present various examples of widely prescribed drugs that can precipitate micronutrient deficiencies. This review aims at sensitizing physicians on drug-micronutrient interactions. High-risk population groups also are presented and supplementation protocols are suggested.

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Crossref · 10.1016/j.nut.2012.11.011

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Authors
Samaras, D., Samaras, N., Lang, P.-O., Genton, L., Frangos, E., & Pichard, C.
Affiliations
  • University Hospital of Geneva (CH)
  • University of Geneva (CH)
  • Clinique de Genolier (CH)
Corresponding author
Pichard, Claude
Venue
Nutrition
Publisher
Elsevier BV
Published
2013-04
Volume
29
Issue
4
Pages
605-610
ISSN
0899-9007 (ISSN-L)
OpenAlex
W1994444904
Cited by
36
References
78
Citations by year
2026: 4 · 2025: 3 · 2024: 2 · 2023: 2 · 2022: 2 · 2021: 1 · 2020: 3 · 2019: 3 · 2018: 4 · 2017: 2 · 2016: 3 · 2015: 4 · 2014: 2 · 2013: 1
FWCI
0.38
Type
journal article
Language
en
Open access
Locations
  • Nutrition (publishedVersion)
  • PubMed (publishedVersion)
  • Archive ouverte UNIGE (University of Geneva) (submittedVersion, cc-by)
Topics
  • Health Sciences › Nursing › Nutrition and Dietetics › Trace Elements in Health
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutrition and Health Studies
  • Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
Keywords
micronutrient deficiency, vitamins, trace elements, medication adherence, supplementation, vulnerable populations, drug metabolism
MeSH terms
Animals, Deficiency Diseases, Humans, Risk, Food-Drug Interactions, Micronutrients, Dietary Supplements, Prescription Drugs

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