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Cited by 58Resilience and Mental HealthPersonality Traits and PsychologyOptimism, Hope, and Well-being

Personality, cognitive/psychological traits and psychiatric resilience: a multivariate twin study

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Amstadter, Ananda B., Moscati, Arden, Maes, Hermine H., Myers, John M., Kendler, Kenneth S.·2016·Personality and Individual Differences
DOI 10.1016/j.paid.2015.11.041PMC PMC5667653
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Abstract

The purpose of this paper is to determine the phenotypic relationships, and etiologic underpinnings, of cognitive/psychological traits with psychiatric resilience. Resilience was defined as the difference between the twins' total score on a broad measure of internalizing symptoms and their predicted score based on their cumulative exposure to stressful life events (SLEs). Cholesky decompositions were performed in a large twin sample (n=7,500 individuals) to quantify the overlap in genetic and environmental factors between resilience and six traits (neuroticism, optimism, self-esteem, mastery, interpersonal dependency, altruism) in bivariate analyses, and in a multivariate model. On a phenotypic level, each trait accounted for variance in resilience in univariate analyses. In the multivariate regression neuroticism accounted for the majority of the variance and attenuated the relationships between the other traits and resilience. The genetic factors that influence the traits account for between 7-60% of the heritability of resilience. In the multivariate genetic model neuroticism accounted for all of the genetic covariance between the traits and resilience; 40% of the genetic influence on resilience was independent. Neuroticism evidenced the largest phenotypic and genetic relationship with resilience, and accounted for nearly all of the phenotypic and genetic variance between resilience and the other traits.

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  • The heritability of resilience is low to moderate, varying in research reports from 25% to 60%.

    “Similarly, the heritability of resilience is low to moderate, varying in research reports from 25% to 60% (32–34).”

    From Epigenetic Modifications in Stress Response Genes Associated With Childhood Trauma (2019) · cites this paper as [34]

    The Introduction (p. not supplied) describes resilience heritability as modest to moderate, reporting approximately 31% in univariate models and 50% for a latent construct; Results §3.2 reports 33–34%. The paper does not substantiate the claimed 25%–60% range. Its 60% figure in Results §3.3 is the share of genetic variance overlapping with other traits, not resilience heritability. (LLM, conf=0.88)

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Research works printed but not linked: 1

  1. [10]Rutter M Implications of resilience concepts for scientific understanding Annals of the New York Academy of Sciences 1094 1 12 10.1196/annals.1376.002 2006 17347337 · DOI · Paper page

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Authors
Amstadter, A. B., Moscati, A., Maes, H. H., Myers, J. M., & Kendler, K. S.
Affiliations
Virginia Commonwealth University (US)
Corresponding author
Amstadter, Ananda B.
ORCID
Venue
Personality and Individual Differences
Publisher
Elsevier BV
Published
2016-03
Volume
91
Pages
74-79
ISSN
0191-8869 (ISSN-L)
DOI
10.1016/j.paid.2015.11.041
PMC
PMC5667653
OpenAlex
W2189435176
Cited by
58
References
45
Citations by year
2026: 2 · 2025: 4 · 2024: 2 · 2023: 6 · 2022: 6 · 2021: 11 · 2020: 10 · 2019: 6 · 2018: 3 · 2017: 5 · 2016: 3
FWCI
4.55
Type
journal article
Language
en
Open access
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Personality and Individual Differences (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
NIH (K02AA023239, R01 AA020179, P20 AA107828, R37 AA011408)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Resilience and Mental Health
  • Social Sciences › Psychology › Clinical Psychology › Personality Traits and Psychology
  • Social Sciences › Psychology › Applied Psychology › Optimism, Hope, and Well-being
Keywords
neuroticism, optimism, self-esteem, mastery, interpersonal dependency, altruism, internalizing problems, life events, heritability, genetic covariance, personality traits, twin studies

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