Exercise training intensity/volume affects plasma and tissue adiponectin concentrations in the male rat

Garekani, Elahe Talebi; Mohebbi, Hamid; Kraemer, Robert R.; Fathi, Rozita

doi:10.1016/j.peptides.2011.01.027

Cited by 77Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and MetabolismExercise and Physiological Responses

Exercise training intensity/volume affects plasma and tissue adiponectin concentrations in the male rat

Garekani, Elahe Talebi, Mohebbi, Hamid, Kraemer, Robert R., Fathi, Rozita·2011·Peptides

DOI 10.1016/j.peptides.2011.01.027

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Abstract

The objective of the study was to determine the effects of exercise training intensity/volume on plasma total and high molecular weight (HMW) adiponectin and tissue total adiponectin concentrations. Thirty-two, eight week-old male Wistar rats (185 ± 5g) were randomly assigned to one of four groups: high intensity (HI: 34 m/min ∼%80-%85 VO(2)max), moderate intensity (MI: 28 m/min ∼%70-%75 VO(2)max), low intensity (LI: 20 m/min ∼ %50-%55 VO(2)max), and sedentary control (SED). Experimental groups completed a 12-week exercise program of treadmill running at 0° slope, 1h/day, 5 days/week. Since frequency and duration of exercise were identical among training groups, the volume of training was highest in the HI group followed by the MI and LI groups. Compared with SED animals, fasting plasma total and HMW adiponectin and adipose tissue total adiponectin concentrations were significantly higher in the HI and MI groups, but total adiponectin concentrations in liver and soleus muscle were not significantly lower than the SED rats. There were significantly lower plasma total testosterone levels in the HI group vs. SED group. Plasma total and HMW adiponectin were negatively correlated with HOMA-IR and insulin whereas total adiponectin was inversely related to TNF-α and HMW adiponectin was negatively correlated with total testosterone. Thus, data suggest there is a dose effect for exercise training intensity and accompanying volume for the adaptation of adipose tissue and circulating total and HMW adiponectin concentrations, whereas the changes of adiponectin concentrations in skeletal muscle and liver tissue may depend on the body's energy balance in the recovery period.

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From Adiponectin and Its Mimics on Skeletal Muscle: Insulin Sensitizers, Fat Burners, Exercise Mimickers, Muscling Pills … or Everything Together? (2020) · cites this paper as [79]
These rises correlated with insulin sensitivity.
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From Adiponectin and Its Mimics on Skeletal Muscle: Insulin Sensitizers, Fat Burners, Exercise Mimickers, Muscling Pills … or Everything Together? (2020) · cites this paper as [79]

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Authors: Garekani, E. T., Mohebbi, H., Kraemer, R. R., & Fathi, R.
Affiliations: University of Guilan (IR)
Southeastern Louisiana University (US)
University of Mazandaran (IR)
Corresponding author: Kraemer, Robert R.
ORCID: Mohebbi, Hamid
Kraemer, Robert R.
Fathi, Rozita
Venue: Peptides
Publisher: Elsevier BV
Published: 2011-05
Volume: 32
Issue: 5
Pages: 1008-1012
ISSN: 0196-9781 (ISSN-L)
DOI: 10.1016/j.peptides.2011.01.027
OpenAlex: W2088690141
Cited by: 77
References: 48
Citations by year: 2026: 2 · 2025: 3 · 2024: 3 · 2023: 3 · 2022: 4 · 2021: 9 · 2020: 6 · 2019: 9 · 2018: 6 · 2017: 3 · 2016: 9 · 2015: 3 · 2014: 7 · 2013: 6 · 2012: 3
FWCI: 4.10
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Peptides (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
Health Sciences › Medicine › Physiology › Adipose Tissue and Metabolism
Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
Keywords: adiponectin, high molecular weight adiponectin, exercise training intensity, exercise volume, treadmill running, adipose tissue, liver, soleus muscle, testosterone, insulin resistance, HOMA-IR, TNF-α, dose-response relationship, energy balance, rats
MeSH terms: Animals, Male, Physical Conditioning, Animal, Rats, Wistar, Muscle, Skeletal, Rats, Adiponectin

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Exercise training intensity/volume affects plasma and tissue adiponectin concentrations in the male rat

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