Cited by 68Plant Stress Responses and TolerancePlant-Microbe Interactions and ImmunityPlant Growth Enhancement Techniques

Exogenous abscisic acid mediates ROS homeostasis and maintains glandular trichome to enhance artemisinin biosynthesis in Artemisia annua under copper toxicity

Zehra, Andleeb, Choudhary, Sadaf, Wani, Kaiser Iqbal, Naeem, M., Khan, M. Masroor A., Aftab, Tariq·2020·Plant Physiology and Biochemistry

Abstract

One of the major abiotic stresses that cause environmental pollution is heavy metal stress. In the present investigation, copper (Cu) toxicity caused morphological and cellular damages to the Artemisia annua L. plants but supplementation of abscisic acid (ABA) ameliorated the damaging effect of Cu. Copper toxicity significantly reduced the shoot and root lengths; fresh and dry weights of shoot. However, exogenous application of ABA to Cu-treated plants significantly attenuated the damaging effects on plants caused by Cu toxicity. Copper stress also reduced the physiological and biochemical parameters, but ABA application ameliorated the negative effects of Cu in the affected plant. Accumulation of Cu in plant tissues significantly increased the membrane damage and oxidative enzyme activities such as catalase (CAT), peroxidase (POX) and superoxide dismutase (SOD). Further, the impact of high concentration of Cu on density, area and ultrastructure of glandular trichomes and artemisinin content was studied. Moreover, the foliar application of ABA improved the area, density of glandular trichomes and secured the plant cells from Cu toxicity. Therefore, this investigation indicated that the exogenous application of ABA protects A. annua plant by increasing antioxidant enzymes activity, which helps in maintaining cell integrity of leaves and results in increased artemisinin production.

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Crossref · 10.1016/j.plaphy.2020.08.048

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  • Abscisic acid positively affects artemisinin content and yield in plants as well as in suspension cultures by increasing expression of key artemisinin biosynthetic genes including ADS, CYP71AV1, DBR2 and ALDH1.

    “Abscisic acid positively affects artemisinin content and yield in plants as well as in suspension cultures by increasing expression of certain key artemisinin biosynthetic genes including ADS, CYP71AV1, DBR2 and ALDH1 (Zehra et al. 2020; Zebarjadi et al. 2018; Jing et al. 2009).”

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Authors
Zehra, A., Choudhary, S., Wani, K. I., Naeem, M., Khan, M. M. A., & Aftab, T.
Affiliations
Aligarh Muslim University (IN)
Corresponding author
Aftab, Tariq
Venue
Plant Physiology and Biochemistry
Publisher
Elsevier BV
Published
2020-11
Volume
156
Pages
125-134
ISSN
0981-9428 (ISSN-L)
OpenAlex
W3084389578
Cited by
67
References
100
Citations by year
2026: 6 · 2025: 13 · 2024: 13 · 2023: 12 · 2022: 11 · 2021: 12
FWCI
5.65
Type
journal article
Language
en
Open access
closed
Locations
  • Plant Physiology and Biochemistry (publishedVersion)
  • PubMed (publishedVersion)
Funders
University Grants Commission
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Stress Responses and Tolerance
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant-Microbe Interactions and Immunity
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Growth Enhancement Techniques
Keywords
abscisic acid, copper toxicity, heavy metal stress, Artemisia annua, artemisinin biosynthesis, glandular trichomes, reactive oxygen species homeostasis, antioxidant enzymes, oxidative stress, stress reduction, foliar application
MeSH terms
Abscisic Acid, Copper, Homeostasis, Reactive Oxygen Species, Plant Leaves, Artemisia annua, Artemisinins, Trichomes

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