Cited by 113Coffee research and impactsSleep and Work-Related FatigueSleep and related disorders

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Early effects of caffeinated and decaffeinated coffee on subjective state and gender differences

Adan, Ana, Prat, Gemma, Fabbri, Marco, Sànchez-Turet, Miquel·2008·Progress in Neuro-Psychopharmacology and Biological Psychiatry

DOI 10.1016/j.pnpbp.2008.07.005

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Abstract

Objectives Some previous studies have demonstrated an early effect of caffeine administration on subjective state, but none of them has explored its existence after the administration of decaffeinated coffee, or the possible differences depending on the gender and circadian typology of the subjects. The aim of the present work is to investigate the early effects (10-30 min post-consumption) of a single low dose of caffeine (100 mg) and decaffeinated coffee on sleepiness, subjective activation and affect using a realistic design. The influence of gender and circadian typology is also explored.Methods A randomized double-blind informed placebo controlled procedure was applied to 688 healthy undergraduate volunteers, mean age 22.03+/-2.21 years, 238 men and 450 women. Measures were recorded before and after beverage consumption (10, 20 and 30 min), in two experimental sessions: morning 11:00-13:00 h or afternoon 16:00-18:00 h.Results Caffeine administration induced arousing effects (lesser somnolence and greater activation) in all post-consumption records, while the effects of decaffeinated drink were only apparent at 10 min. Caffeine effects were greater in men, and the decaffeinated beverage produced greater effects in women. Circadian typology only showed effects for time of day (morning/afternoon) related with rhythmic expression.Conclusion Future works should study more accurately the early effect of coffee beverages and the influence of gender, using other parameters which have proven to be sensitive to their administration. The effect of several caffeine doses should also be studied.

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Authors: Adan, A., Prat, G., Fabbri, M., & Sànchez-Turet, M.
Affiliations: Universitat de Barcelona (ES)
ORCID: Prat, Gemma
Fabbri, Marco
Venue: Progress in Neuro-Psychopharmacology and Biological Psychiatry
Publisher: Elsevier BV
Published: 2008-10
Volume: 32
Issue: 7
Pages: 1698-1703
ISSN: 0278-5846 (ISSN-L)
DOI: 10.1016/j.pnpbp.2008.07.005
OpenAlex: W2089667241
Cited by: 113
References: 42
Citations by year: 2026: 3 · 2025: 4 · 2024: 6 · 2023: 10 · 2022: 12 · 2021: 5 · 2020: 5 · 2019: 9 · 2018: 11 · 2017: 7 · 2016: 4 · 2015: 7 · 2014: 5 · 2013: 3 · 2012: 10
FWCI: 2.77
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Progress in Neuro-Psychopharmacology and Biological Psychiatry (publishedVersion)
PubMed (publishedVersion)
Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna) (submittedVersion)
Archivio Istituzionale della Ricerca - Università degli Studi della Campania "Luigi Vanvitelli" (submittedVersion)
Topics: Health Sciences › Medicine › Pharmacology (medical) › Coffee research and impacts
Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
Keywords: caffeine, decaffeinated coffee, sleepiness, affect, gender differences, chronotype, time of day
MeSH terms: Adult, Central Nervous System Stimulants, Beverages, Caffeine, Circadian Rhythm, Double-Blind Method, Female, Humans, Male, Pain Measurement, Surveys and Questionnaires, Sex Characteristics, Sleep, Time Factors, Multivariate Analysis

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Early effects of caffeinated and decaffeinated coffee on subjective state and gender differences

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