The DOI matches its Crossref record; 57 of the 57 references it cites were found in a registry or an index.
Amygdala hyperreactivity in restrictive anorexia nervosa
Abstract
Functional imaging studies had often investigated heterogeneous samples of anorexia nervosa (AN) patients with varying paradigms and methodologies that had resulted in divergent results. The present study aimed to examine these issues by studying a well-defined sample of restrictive AN patients with a disorder-specific paradigm which had been used previously. Subjects showed increased blood oxygen level dependent responses of the cingulate, frontal, insular and parietal cortices. Group comparisons demonstrated increased activity of the right amygdala in the sample of restrictive AN patients. Our results are in support of other recently published functional imaging studies and point to a pivotal role of the right amygdala in AN. Signals of the midcingulum were reduced in comparison to healthy controls. The constellation of increased activity of the amygdala and decreased activity of the cingulate cortex likely represents parts of a negative feedback loop of emotional processing. Disgust ratings correlated with the amygdala signal negatively, which points to the complex role of this structure within eating disorders.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Several studies have reported reduced reward motivation for food rewards in eating disorders.”
From Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings (2012) · cites this paper as [321]
In the citing paper
“Joos and colleagues [321] found reduced activation of the ACC in individuals with concurrent BN during the presentation of visual food cues”
From Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings (2012) · cites this paper as [321]
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
International Affective Picture System (IAPS) : Technical Manual and Affective Ratings
Lang, P. J. (1995) · Medical Entomology and Zoology · Cited by 2,870
Development of the adolescent brain: implications for executive function and social cognition
Blakemore, S., & Choudhury, S. (2006) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2006.01611.x · Cited by 2,328
Neurobiology of emotion perception I: the neural basis of normal emotion perception
Phillips, M. L., Drevets, W. C., Rauch, S. L., & Lane, R. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00168-9 · Cited by 2,173
Fairburn, C. G., & Harrison, P. J. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12378-1 · Cited by 1,396
Diagnostic and Statistical Manual of Mental Disorders
Preedy, V., & Watson, R. (2010) · Springer eBooks · doi:10.1007/978-0-387-78665-0_5485 · Cited by 1,146
Sergerie, K., Chochol, C., & Armony, J. L. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2007.12.002 · Cited by 917
Costafreda, S. G., Brammer, M. J., David, A. S., & Fu, C. H. Y. (2008) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.10.012 · Cited by 772
Hautzinger, M., Keller, F., & Kühner, C. (2006) · Cited by 663
Neurobiology of anorexia and bulimia nervosa
Kaye, W. (2008) · Physiology & Behavior · doi:10.1016/j.physbeh.2007.11.037 · Cited by 625
Neural Correlates of Positive and Negative Emotion Regulation
Kim, S. H., & Hamann, S. (2007) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2007.19.5.776 · Cited by 615 · cited 1×
“With respect to laterality of amygdala function, an investigation of neural correlates of emotion regulation yielded differences between right- and left-sided amygdalae, the former being particularly active in response to positive stimuli (Kim and Hamann, 2007).”
BackgroundNyman‐Carlsson, E., & Garner, D. M. (2017) · Springer eBooks · doi:10.1007/978-981-287-104-6_192 · Cited by 595
Individual Differences in Reward Drive Predict Neural Responses to Images of Food
Beaver, J. D., Lawrence, A. D., van Ditzhuijzen, J., Davis, M. H., Woods, A., & Calder, A. J. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.0350-06.2006 · Cited by 594
Cortical and limbic activation during viewing of high- versus low-calorie foods
Killgore, W. D. S., Young, A. D., Femia, L. A., Bogorodzki, P., Rogowska, J., & Yurgelun-Todd, D. A. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00191-5 · Cited by 581
Medial prefrontal cortex activity associated with symptom provocation in eating disorders
Uher, R., Murphy, T., Brammer, M. J., Dalgleish, T., Phillips, M. L., Ng, V. W., Andrew, C. M., Williams, S. C. R., Campbell, I. C., & Treasure, J. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.7.1238 · Cited by 452
Binge-Eating Disorder: Reward Sensitivity and Brain Activation to Images of Food
Schienle, A., Schäfer, A., Hermann, A., & Vaitl, D. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.09.028 · Cited by 447
Hunger selectively modulates corticolimbic activation to food stimuli in humans
LaBar, K. S., Gitelman, D. R., Parrish, T. B., Kim, Y.-H., Nobre, A. C., & Mesulam, M. M. (2001) · Behavioral Neuroscience · doi:10.1037/0735-7044.115.2.493 · Cited by 444
A validated network of effective amygdala connectivity
Stein, J. L., Wiedholz, L. M., Bassett, D. S., Weinberger, D. R., Zink, C. F., Mattay, V. S., & Meyer-Lindenberg, A. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.03.022 · Cited by 392
Siep, N., Roefs, A., Roebroeck, A., Havermans, R., Bonte, M. L., & Jansen, A. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.10.035 · Cited by 375
Medial prefrontal cortex activity associated with symptom provocation in eating disorders
Uher, R., Murphy, T. L., Brammer, M. J., Dalgleish, T., Phillips, M. L., Ng, V., Andrew, C., Williams, S., Campbell, I. C., & Treasure, J. L. (2004) · Research Portal (King's College London) · Cited by 361
Friborg, O., Clausen, L., & Rosenvinge, J. H. (2013) · PsycTESTS Dataset · doi:10.1037/t62782-000 · Cited by 359
More accurate Talairach coordinates for neuroimaging using non-linear registration
Lacadie, C., Fulbright, R. K., Rajeevan, N., Constable, R. T., & Papademetris, X. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.04.240 · Cited by 351
Effect of a single dose of citalopram on amygdala response to emotional faces
Murphy, S. E., Norbury, R., O'Sullivan, U., Cowen, P. J., & Harmer, C. J. (2009) · British Journal of Psychiatry · doi:10.1192/bjp.bp.108.056093 · Cited by 255
Functional Neuroanatomy of Body Shape Perception in Healthy and Eating-Disordered Women
Uher, R., Murphy, T. L., Friederich, H., Dalgleish, T., Brammer, M. J., Giampietro, V., Phillips, M. L., Andrew, C. M., Ng, V., Williams, S., et al. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.06.001 · Cited by 247
A Neural Signature of Anorexia Nervosa in the Ventral Striatal Reward System
Fladung, A.-K., Grön, G., Grammer, K., Herrnberger, B., Schilly, E., Grasteit, S., Wolf, R. C., Walter, H., & von Wietersheim, J. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2009.09010071 · Cited by 220
Recovery and chronicity in anorexia nervosa
Uher, R., Brammer, M. J., Murphy, T. L., Campbell, I. C., Ng, V., Williams, S., & Treasure, J. L. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00172-0 · Cited by 219
Brain activity in hunger and satiety: an exploratory visually stimulated fMRI study
Führer, D., Zysset, S., & Stumvoll, M. (2008) · Obesity · doi:10.1038/oby.2008.33 · Cited by 218
Born, J. R., Lemmens, S. G. T., Rutters, F., Nieuwenhuizen, A. G., Formisano, E., Goebel, R., & Westerterp‐Plantenga, M. S. (2009) · International Journal of Obesity · doi:10.1038/ijo.2009.221 · Cited by 200
Hunger and satiety in anorexia nervosa: fMRI during cognitive processing of food pictures
Santel, S., Baving, L., Krauel, K., Münte, T. F., & Rotte, M. (2006) · Brain Research · doi:10.1016/j.brainres.2006.07.045 · Cited by 194
Functional anatomy of calorie fear in anorexia nervosa
Ellison, Z., Foong, J., Howard, R. J., Bullmore, E. T., Williams, S., & Treasure, J. L. (1998) · The Lancet · doi:10.1016/s0140-6736(05)60529-6 · Cited by 186
A cross-sectional and follow-up voxel-based morphometric MRI study in adolescent anorexia nervosa
Castro‐Fornieles, J., Bargalló, N., Lázaro, L., Andrés, S., Falcón, C., Plana, M. T., & Junqué, C. (2008) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2008.03.013 · Cited by 177
Ball, T., Rahm, B., Eickhoff, S. B., Schulze-Bonhage, A., Speck, O., & Mutschler, I. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000307 · Cited by 176
Vocks, S., Busch, M., Grönemeyer, D. H. W., Schulte, D., Herpertz, S., & Boris Suchan, A. (2010) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.090048 · Cited by 174
Seeger, G., Braus, D. F., Ruf, M., Goldberger, U., & Schmidt, M. H. (2002) · Neuroscience Letters · doi:10.1016/s0304-3940(02)00312-9 · Cited by 173
Sachdev, P. S., Mondraty, N., Wen, W. X., & Gulliford, K. (2008) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2008.02.031 · Cited by 169
Gray Matter Decrease of the Anterior Cingulate Cortex in Anorexia Nervosa
Mühlau, M., Gaser, C., Ilg, R., Conrad, B., Leibl, C., Cebulla, M. H., Backmund, H., Gerlinghoff, M., Lommer, P., Schnebel, A., et al. (2007) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.06111861 · Cited by 169
Psychophysiological indices of cerebral maturation
Hudspeth, W. J., & Pribram, K. H. (1992) · International Journal of Psychophysiology · doi:10.1016/0167-8760(92)90039-e · Cited by 167
Neuronal activity changes and body image distortion in anorexia nervosa
Wagner, A., Ruf, M., Braus, D. F., & Schmidt, M. H. (2003) · Neuroreport · doi:10.1097/00001756-200312020-00012 · Cited by 162
The neuropsychological impact of insular cortex lesions
Jones, C. L., Ward, J., & Critchley, H. D. (2010) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.2009.193672 · Cited by 158
Separating two components of body image in anorexia nervosa using fMRI
Mohr, H., Zimmermann, J., Röder, C. H., Lenz, C., Overbeck, G., & Grabhorn, R. (2009) · Psychological Medicine · doi:10.1017/s0033291709991826 · Cited by 157
Validity and utility of subtyping anorexia nervosa
Peat, C. M., Mitchell, J. E., Hoek, H. W., & Wonderlich, S. A. (2009) · International Journal of Eating Disorders · doi:10.1002/eat.20717 · Cited by 140
Voxel-based morphometry in eating disorders: Correlation of psychopathology with grey matter volume
Joos, A. A. B., Klöppel, S., Hartmann, A., Glauche, V., Tüscher, O., Perlov, E., Saum, B., Freyer, T., Zeeck, A., & van Elst, L. T. (2010) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2010.02.004 · Cited by 125
Self-citationAbnormal neuronal network in anorexia nervosa studied with I-123-IMP SPECT
Takano, A., Shiga, T., Kitagawa, N., Koyama, T., Katoh, C., Tsukamoto, E., & Tamaki, N. (2001) · Psychiatry Research Neuroimaging · doi:10.1016/s0925-4927(01)00093-2 · Cited by 121
Brain activation during the perception of distorted body images in eating disorders
Miyake, Y., Okamoto, Y., Onoda, K., Kurosaki, M., Shirao, N., Okamoto, Y., & Yamawaki, S. (2010) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2009.09.001 · Cited by 118
Windischberger, C., Lanzenberger, R., Holik, A., Spindelegger, C., Stein, P., Moser, U., Gerstl, F., Fink, M., Moser, E., & Kasper, S. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2009.10.013 · Cited by 114
Towards a neurocircuitry in anorexia nervosa: Evidence from functional neuroimaging studies
van Kuyck, K., Gérard, N., Laere, K. V., Casteels, C., Pieters, G., Gabriëls, L. A., & Nuttin, B. (2009) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2009.04.005 · Cited by 106
Townsend, J. D., Eberhart, N. K., Bookheimer, S. Y., Eisenberger, N. I., Foland-Ross, L. C., Cook, I. A., Sugar, C. A., & Altshuler, L. L. (2010) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2010.06.001 · Cited by 105
Miyake, Y., Okamoto, Y., Onoda, K., Shirao, N., Okamoto, Y., Otagaki, Y., & Yamawaki, S. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2009.12.095 · Cited by 102
Anatomical changes in the emerging adult brain: A voxel‐based morphometry study
Bennett, C. M., & Baird, A. A. (2005) · Human Brain Mapping · doi:10.1002/hbm.20218 · Cited by 99
Ball, T., Derix, J., Wentlandt, J., Wieckhorst, B., Speck, O., Schulze‐Bonhage, A., & Mutschler, I. (2009) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2009.02.022 · Cited by 89
Naruo, T., Nakabeppu, Y., Deguchi, D., Nagai, N., Tsutsui, J., Nakajo, M., & Nozoe, S.-I. (2001) · BMC Psychiatry · doi:10.1186/1471-244x-1-2 · Cited by 83
Vocks, S., Herpertz, S., Rosenberger, C., Senf, W., & Gizewski, E. R. (2010) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2010.07.012 · Cited by 82
Gizewski, E. R., Rosenberger, C., de Greiff, A., Moll, A., Senf, W., Wanke, I., Forsting, M., & Herpertz, S. (2010) · Neuropsychobiology · doi:10.1159/000319360 · Cited by 69
Emotional perception in eating disorders
Joos, A. A. B., Cabrillac, E., Hartmann, A., Wirsching, M., & Zeeck, A. (2008) · International Journal of Eating Disorders · doi:10.1002/eat.20621 · Cited by 47
Self-citation[The multiple selection vocabulary test (MSVT-B)--an accelerated intelligence test].
Merz, J., Lehrl, S., Galster, V., & Erzigkeit, H. (1975) · PubMed · Cited by 39
ANOREXIA NERVOSA SUBTYPES: DIFFERENCES IN RECOVERY
Ward, A., Campbell, I. C., Brown, N. W., & Treasure, J. L. (2003) · The Journal of Nervous and Mental Disease · doi:10.1097/01.nmd.0000055082.75337.21 · Cited by 14
Anorexia nervosa subtypes: Differences in recovery
Ward, A., Campbell, I. C., Brown, N. W., & Treasure, J. L. (2003) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-200303000-00011 · Cited by 3
Research works printed but not linked: 1
- Merz, 1975, MWT-B - ein Intelligenzkurztest, Psychiatrie, Neurologie und Medizinische Psychologie, 27, 423
Cited by
Sorted by citations
Dichter, G. S., Damiano, C. A., & Allen, J. A. (2012) · Journal of Neurodevelopmental Disorders · doi:10.1186/1866-1955-4-19 · Cited by 299
“[321] found reduced activation of the ACC in individuals with concurrent BN during the presentation of visual food”
BackgroundO'Hara, C., Campbell, I. C., & Schmidt, U. H. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.02.012 · Cited by 271
Increased neural processing of rewarding and aversive food stimuli in recovered anorexia nervosa
Cowdrey, F. A., Park, R. J., Harmer, C. J., & McCabe, C. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.05.028 · Cited by 233
Holsen, L. M., Lawson, E. A., Blum, J. I., Ko, E., Makris, N., Fazeli, P. K., Klibanski, A., & Goldstein, J. M. (2012) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.110156 · Cited by 183
Neural basis of a multidimensional model of body image distortion in anorexia nervosa
Gaudio, S., & Quattrocchi, C. C. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2012.05.003 · Cited by 182
Metadata
- Authors
- Joos, A. A. B., Saum, B., van Elst, L. T., Perlov, E., Glauche, V., Hartmann, A., Freyer, T., Tüscher, O., & Zeeck, A.
- Affiliations
- University of Freiburg (DE)
- Corresponding author
- Joos, Andreas A.B.
- Venue
- Psychiatry Research: Neuroimaging
- Publisher
- Elsevier BV
- Published
- 2011-03
- Volume
- 191
- Issue
- 3
- Pages
- 189-195
- ISSN
- 0925-4927 (ISSN-L)
- OpenAlex
- W2126841876
- Cited by
- 124
- References
- 57
- Citations by year
- 2026: 5 · 2025: 10 · 2024: 8 · 2023: 9 · 2022: 10 · 2021: 12 · 2020: 5 · 2019: 9 · 2018: 9 · 2017: 3 · 2016: 8 · 2015: 6 · 2014: 6 · 2013: 9 · 2012: 12
- FWCI
- 10.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychiatry Research Neuroimaging (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Albert-Ludwigs-Universität Freiburg
- Topics
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Keywords
- anorexia nervosa, restrictive anorexia nervosa, right amygdala, midcingulate cortex, emotional processing, disgust, eating disorders, brain activity
- MeSH terms
- Adult, Amygdala, Anorexia Nervosa, Brain Mapping, Cerebral Cortex, Emotions, Female, Food, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Oxygen, Photic Stimulation, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
