Cited by 149Schizophrenia research and treatmentPhysical Activity and HealthObesity, Physical Activity, Diet

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Associations between sedentary behaviour and metabolic parameters in patients with schizophrenia

Vancampfort, Davy, Probst, Michel, Knapen, Jan, Carraro, Attilio, De Hert, Marc·2012·Psychiatry Research

DOI 10.1016/j.psychres.2012.03.046

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Abstract

This study examined the association between sedentary behaviour and metabolic parameters among patients with schizophrenia. A total of 76 patients and 38 healthy age-, gender- and BMI-matched volunteers were included. Participants were asked for their overall sitting and physical activity behaviour using the International Physical Activity Questionnaire. Patients were additionally screened for psychiatric symptoms and extrapyramidal side-effects of antipsychotic medication. On average, patients with schizophrenia spent 8.5h per day sitting (versus 6.21h in healthy controls). Patients sitting more than 10.4h per day had a higher BMI, waist circumference and fasting glucose concentrations and experienced more negative and cognitive symptoms than those sitting less than 5.8h per day. Overall sitting time was associated with a significantly greater likelihood of metabolic syndrome. A stepwise backward-elimination multivariate regression analysis demonstrated that sitting time is a significant predictor for BMI. Current results suggest patients with schizophrenia may benefit from reducing total sitting time.

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Authors: Vancampfort, D., Probst, M., Knapen, J., Carraro, A., & De Hert, M.
Affiliations: KU Leuven (BE)
University of Padua (IT)
Corresponding author: Vancampfort, Davy
ORCID: Vancampfort, Davy
Probst, Michel
Carraro, Attilio
Venue: Psychiatry Research
Publisher: Elsevier BV
Published: 2012-12
Volume: 200
Issue: 2-3
Pages: 73-78
ISSN: 0165-1781 (ISSN-L)
DOI: 10.1016/j.psychres.2012.03.046
OpenAlex: W2155434312
Cited by: 149
References: 40
Citations by year: 2026: 1 · 2025: 2 · 2024: 2 · 2023: 17 · 2022: 10 · 2021: 9 · 2020: 11 · 2019: 7 · 2018: 20 · 2017: 15 · 2016: 19 · 2015: 11 · 2014: 9 · 2013: 13 · 2012: 3
FWCI: 8.20
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Psychiatry Research (publishedVersion)
PubMed (publishedVersion)
Lirias (submittedVersion)
Open Research (University of Surrey) (submittedVersion)
Padua Research Archive (University of Padova) (submittedVersion)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Keywords: sedentary behavior, sitting time, schizophrenia, metabolic parameters, metabolic syndrome, body mass index, waist circumference, fasting blood glucose, physical activity, negative symptoms, cognitive symptoms, antipsychotic adverse effects, extrapyramidal symptoms
MeSH terms: Adult, Female, Humans, Male, Middle Aged, Motor Activity, Surveys and Questionnaires, Risk Factors, Schizophrenia, Antipsychotic Agents, Body Mass Index, Metabolic Syndrome, Waist Circumference, Sedentary Behavior

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Associations between sedentary behaviour and metabolic parameters in patients with schizophrenia

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