CoChat
Sign Up
Cited by 65Heart Rate Variability and Autonomic ControlNeuroscience of respiration and sleepCardiovascular and exercise physiology

Increased cardio-respiratory coupling evoked by slow deep breathing can persist in normal humans

Open access
Dick, Thomas E., Mims, Joseph R., Hsieh, Yee-Hsee, Morris, Kendall F., Wehrwein, Erica A.·2014·Respiratory Physiology & Neurobiology
DOI 10.1016/j.resp.2014.09.013PMC PMC4252616
Open this paper in CoChat — free account

Abstract

Slow deep breathing (SDB) has a therapeutic effect on autonomic tone. Our previous studies suggested that coupling of the cardiovascular to the respiratory system mediates plasticity expressed in sympathetic nerve activity. We hypothesized that SDB evokes short-term plasticity of cardiorespiratory coupling (CRC). We analyzed respiratory frequency (fr), heart rate and its variability (HR&HRV), the power spectral density (PSD) of blood pressure (BP) and the ventilatory pattern before, during, and after a 20-min epoch of SDB. During SDB, CRC and the relative PSD of BP at fr increased; mean arterial pressure decreased; but HR varied; increasing (n=3), or decreasing (n=2) or remaining the same (n=5). After SDB, short-term plasticity was not apparent for the group but for individuals differences existed between baseline and recovery periods. We conclude that a repeated practice, like pranayama, may strengthen CRC and evoke short-term plasticity effectively in a subset of individuals.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.resp.2014.09.013

Cites

87 of 87 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Several studies have reported significantly decreased mean blood pressure during controlled slow respiration.

    “Several studies have also reported significantly decreased mean blood pressure during controlled slow respiration, which would support this hypothesis [30, 41, 43, 44].”

    From The physiological effects of slow breathing in the healthy human (2017) · cites this paper as [30]

  • Slow breathing towards a rate of 6 breaths per min results in increased venous return.

    “Slow breathing towards a rate of 6 breaths per min has been said to result in increased venous return [30].”

    From The physiological effects of slow breathing in the healthy human (2017) · cites this paper as [30]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

1 of the 88 references couldn’t be matched to a known paper.

Research works printed but not linked: 2

  1. Koepchen HP Thurau K Origin of respiratory arrhythmia Pflugers Arch 1957 266 22 23 13527110
  2. Taylor JA Studinger P Counterpoint: cardiovascular variability is not an index of autonomic control of the circulation J Appl Physiol 2006 101 678 681 discussion 681 16892500

Cited by

Sorted by citations

Related

Authors
Dick, T. E., Mims, J. R., Hsieh, Y.-H., Morris, K. F., & Wehrwein, E. A.
Affiliations
  • Case Western Reserve University (US)
  • University of South Florida (US)
  • Michigan State University (US)
Corresponding author
Dick, Thomas E.
ORCID
Venue
Respiratory Physiology & Neurobiology
Publisher
Elsevier BV
Published
2014-12
Volume
204
Pages
99-111
ISSN
1569-9048 (ISSN-L)
DOI
10.1016/j.resp.2014.09.013
PMC
PMC4252616
OpenAlex
W2059659527
Semantic Scholar
72b6368c687952d7df4ef95e6348b2a631e32ea7
Cited by
65
References
88
Citations by year
2025: 4 · 2024: 15 · 2023: 8 · 2022: 3 · 2021: 7 · 2020: 7 · 2019: 5 · 2018: 5 · 2017: 3 · 2016: 4 · 2015: 3 · 2014: 1
FWCI
2.50
Type
journal article
Language
en
Open access
Licence
Locations
  • Respiratory Physiology & Neurobiology (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • NS069220
  • R25-HL03152
  • HL 083947
  • T32-DK07352
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroscience of respiration and sleep
  • Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
Keywords
cardiorespiratory coupling, slow deep breathing, pranayama, autonomic tone, short-term plasticity, heart rate variability, respiratory rate, sympathetic activity, individual differences
MeSH terms
Adult, Blood Pressure, Breathing Exercises, Heart Rate, Humans, Male, Respiratory Rate

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review