CoChat
Sign Up
Cited by 251Schizophrenia research and treatmentPsychological Testing and AssessmentMental Health and Psychiatry

The DOI matches its Crossref record; 31 of the 32 references it cites were found in a registry or an index.

The MCCB impairment profile for schizophrenia outpatients: Results from the MATRICS psychometric and standardization study

Open access
Kern, Robert S., Gold, James M., Dickinson, Dwight, Green, Michael F., Nuechterlein, Keith H., Baade, Lyle E., Keefe, Richard S.E., Mesholam-Gately, Raquelle I., Seidman, Larry J., Lee, Cathy, Sugar, Catherine A., Marder, Stephen R.·2011·Schizophrenia Research
DOI 10.1016/j.schres.2010.11.008PMC PMC3050090
Open this paper in CoChat — free account

Abstract

The MATRICS Psychometric and Standardization Study was conducted as a final stage in the development of the MATRICS Consensus Cognitive Battery (MCCB). The study included 176 persons with schizophrenia or schizoaffective disorder and 300 community residents. Data were analyzed to examine the cognitive profile of clinically stable schizophrenia patients on the MCCB. Secondarily, the data were analyzed to identify which combination of cognitive domains and corresponding cut-off scores best discriminated patients from community residents, and patients competitively employed vs. those not. Raw scores on the ten MCCB tests were entered into the MCCB scoring program which provided age- and gender-corrected T-scores on seven cognitive domains. To test for between-group differences, we conducted a 2 (group)×7 (cognitive domain) MANOVA with follow-up independent t-tests on the individual domains. Classification and regression trees (CART) were used for the discrimination analyses. Examination of patient T-scores across the seven cognitive domains revealed a relatively compact profile with T-scores ranging from 33.4 for speed of processing to 39.3 for reasoning and problem-solving. Speed of processing and social cognition best distinguished individuals with schizophrenia from community residents; speed of processing along with visual learning and attention/vigilance optimally distinguished patients competitively employed from those who were not. The cognitive profile findings provide a standard to which future studies can compare results from other schizophrenia samples and related disorders; the classification results point to specific areas and levels of cognitive impairment that may advance work rehabilitation efforts.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.schres.2010.11.008

Cites

31 of 31 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Research works printed but not linked: 1

  1. Lukoff, 1986, Appendix A: manual for the expanded brief psychiatric rating scale (BPRS), Schizophr. Bull., 12, 594

Cited by

Sorted by citations

See all 251

Related

See all

Metadata

Authors
Kern, R. S., Gold, J. M., Dickinson, D., Green, M. F., Nuechterlein, K. H., Baade, L. E., Keefe, R. S. E., Mesholam-Gately, R. I., Seidman, L. J., Lee, C., Sugar, C. A., & Marder, S. R.
Affiliations
  • University of California, Los Angeles (US)
  • University of Maryland, Baltimore (US)
  • National Institutes of Health (US)
  • University of Kansas (US)
  • Duke University (US)
  • Beth Israel Deaconess Medical Center (US)
Corresponding author
Kern, Robert S.
ORCID
Venue
Schizophrenia Research
Publisher
Elsevier BV
Published
2011-03
Volume
126
Issue
1-3
Pages
124-131
ISSN
0920-9964 (ISSN-L)
DOI
10.1016/j.schres.2010.11.008
PMC
PMC3050090
OpenAlex
W2128456675
Cited by
251
References
32
Citations by year
2026: 9 · 2025: 17 · 2024: 14 · 2023: 13 · 2022: 16 · 2021: 23 · 2020: 24 · 2019: 20 · 2018: 20 · 2017: 14 · 2016: 10 · 2015: 24 · 2014: 18 · 2013: 12 · 2012: 6
FWCI
6.34
Type
journal article
Language
en
Open access
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Schizophrenia Research (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institutes of Health (n01mh022006-001)
  • National Institute of Mental Health (N01 MH022006)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Social Sciences › Psychology › Applied Psychology › Psychological Testing and Assessment
  • Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
Keywords
schizophrenia, schizoaffective disorder
MeSH terms
Adolescent, Adult, Cognition Disorders, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Outpatients, Psychiatric Status Rating Scales, Psychometrics, Psychotic Disorders, Reference Values, Schizophrenia, Social Adjustment, Young Adult

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review